• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Osl-0169
PURA

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Adenylosuccinate synthetase, chloroplastic
Gene Name: PURA, OSTLU_19549
Ensembl Gene: OSTLU_19549
Ensembl Protein: ABO96441
Organism: Ostreococcus lucimarinus
Taxa ID: 436017
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblABO96441ABO96441
UniProtA4RYD2, PURA_OSTLU
GeneBankCP000586ABO96441.1
RefSeqXM_001418111.1XP_001418148.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRGREDANAR  VLGSQWGDEG  KGKLVDILAR  EYDVVARCQG  GANAGHTIYD  DDGKKYALHL  60
61    VPSGILNENA  TCVVGNGVVV  HLPGMFDEID  ALLKAGVDAR  GRMMVSDRAH  LLFDLHKEID  120
121   GLREAELSGN  KIGTTKRGIG  PAYASKATRN  GVRLGDIRDA  DKFANALRTL  AADAAARFDG  180
181   FEYDVEAEIV  RYREIASRIE  PFIADTVEYV  NDAHRNGKKI  LVEGANATML  DLDFGTYPFV  240
241   TSSNPAIGGV  SNGLGLAPRK  FETIIGVAKA  YTTRVGAGPY  PTELFGDVAD  KLRELGYEYG  300
301   TTTGRPRRIG  WLDMVALNYA  NQINGFTHLN  ITKLDVLSEM  DELKIGVAYE  LPNGKTTTAF  360
361   PADIATLENV  KVVYETLPGW  KTDIANVRSW  DDMPENAKKY  ILRCEELSGV  ECRYIGVGPG  420
421   RDAMVIKP  428
Nucleotide CDS Sequence (FASTA)
1     ATGCGAGGGC  GCGAGGACGC  GAACGCGCGC  GTGCTCGGAA  GCCAGTGGGG  CGACGAGGGC  60
61    AAGGGGAAAT  TAGTGGATAT  TTTGGCGCGC  GAATACGACG  TCGTGGCGAG  ATGTCAAGGC  120
121   GGTGCGAACG  CGGGTCACAC  TATTTATGAC  GATGATGGGA  AGAAGTACGC  GCTGCATCTC  180
181   GTTCCGAGCG  GGATTTTGAA  TGAAAACGCG  ACGTGCGTCG  TCGGCAACGG  CGTCGTGGTG  240
241   CACCTTCCGG  GGATGTTTGA  TGAGATTGAC  GCTTTATTAA  AGGCTGGTGT  GGACGCTCGA  300
301   GGGCGTATGA  TGGTGTCTGA  TCGCGCGCAT  TTGTTGTTCG  ATCTTCATAA  AGAAATCGAT  360
361   GGCTTGCGCG  AGGCGGAGTT  GAGTGGGAAT  AAAATCGGTA  CGACGAAGCG  CGGCATCGGT  420
421   CCCGCGTACG  CCTCCAAAGC  GACGCGCAAC  GGGGTTCGTT  TGGGGGATAT  TCGAGACGCC  480
481   GATAAGTTTG  CGAACGCTTT  GCGCACGCTT  GCGGCGGACG  CGGCGGCTCG  ATTCGATGGT  540
541   TTCGAGTACG  ATGTCGAGGC  GGAGATTGTG  CGATACAGAG  AAATCGCGTC  GCGCATCGAG  600
601   CCGTTCATCG  CGGACACGGT  CGAGTACGTC  AACGACGCGC  ACAGGAACGG  GAAGAAGATC  660
661   TTAGTCGAGG  GTGCGAACGC  GACCATGCTT  GATTTGGATT  TCGGTACGTA  TCCGTTCGTG  720
721   ACGTCCTCCA  ACCCAGCGAT  TGGTGGCGTT  AGCAATGGCC  TCGGTTTGGC  GCCGAGAAAG  780
781   TTTGAAACCA  TCATCGGCGT  CGCCAAGGCG  TACACCACGC  GCGTCGGTGC  GGGTCCGTAC  840
841   CCGACTGAAC  TTTTCGGTGA  CGTCGCCGAT  AAACTCCGCG  AACTCGGCTA  CGAGTACGGC  900
901   ACCACCACCG  GTCGCCCTCG  TCGCATCGGT  TGGTTGGACA  TGGTGGCGTT  GAACTACGCC  960
961   AACCAAATCA  ACGGCTTCAC  GCACTTGAAT  ATCACCAAGC  TCGACGTATT  GAGCGAGATG  1020
1021  GACGAGCTCA  AAATCGGCGT  CGCCTACGAG  CTTCCTAACG  GAAAGACCAC  GACTGCGTTC  1080
1081  CCGGCCGACA  TCGCCACCTT  GGAAAATGTC  AAGGTGGTTT  ACGAAACCTT  GCCCGGTTGG  1140
1141  AAAACCGACA  TCGCAAACGT  GCGCTCTTGG  GACGACATGC  CCGAAAACGC  CAAAAAGTAC  1200
1201  ATTCTTCGCT  GCGAGGAGCT  CTCGGGCGTC  GAGTGTCGCT  ACATTGGCGT  CGGCCCGGGT  1260
1261  CGCGACGCCA  TGGTAATTAA  ACCGTAA  1287

▼ KEYWORD

ID
Family
Chloroplast
Complete proteome
GTP-binding
Ligase
Magnesium
Metal-binding
Nucleotide-binding
Plastid
Purine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apoplast
Cellular Component
Chloroplast stroma
Molecular Function
Adenylosuccinate synthase activity
Molecular Function
GTP binding
Molecular Function
Magnesium ion binding
Biological Process
'de novo' AMP biosynthetic process
Biological Process
Response to cadmium ion

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Php-1841Physcomitrella patens65.950.0 571
LLPS-Sem-0453Selaginella moellendorffii65.00.0 560
LLPS-Chr-1273Chlamydomonas reinhardtii63.90.0 566
LLPS-Orr-0955Oryza rufipogon63.330.0 548
LLPS-Orbr-0602Oryza brachyantha63.330.0 544
LLPS-Orgl-2078Oryza glumaepatula63.330.0 547
LLPS-Mae-0815Manihot esculenta63.10.0 541
LLPS-Orni-1991Oryza nivara63.10.0 545
LLPS-Hov-1464Hordeum vulgare62.950.0 534
LLPS-Coc-1423Corchorus capsularis62.860.0 543
LLPS-Sot-0966Solanum tuberosum62.860.0 546
LLPS-Sei-2295Setaria italica62.80.0 544
LLPS-Prp-1925Prunus persica62.620.0 536
LLPS-Hea-2379Helianthus annuus62.620.0 542
LLPS-Bro-1915Brassica oleracea62.380.0 540
LLPS-Brr-1112Brassica rapa62.380.0 541
LLPS-Nia-2586Nicotiana attenuata62.380.0 547
LLPS-Arl-0264Arabidopsis lyrata62.380.0 540
LLPS-Brn-2145Brassica napus62.230.0 538
LLPS-Pot-2036Populus trichocarpa62.140.0 540
LLPS-Gor-2149Gossypium raimondii62.140.0 536
LLPS-Art-1169Arabidopsis thaliana62.140.0 540
LLPS-Thc-1009Theobroma cacao62.140.0 535
LLPS-Zem-0333Zea mays62.040.0 548
LLPS-Cus-1099Cucumis sativus61.90.0 541
LLPS-Glm-0680Glycine max61.90.0 538
LLPS-Dac-1813Daucus carota61.90.0 539
LLPS-Orp-0898Oryza punctata61.850.0 536
LLPS-Viv-2237Vitis vinifera61.670.0 538
LLPS-Met-2355Medicago truncatula61.670.0 538
LLPS-Ors-1970Oryza sativa61.610.0 533
LLPS-Lep-2353Leersia perrieri61.610.0 535
LLPS-Sob-1512Sorghum bicolor61.570.0 545
LLPS-Org-1697Oryza glaberrima61.370.0 532
LLPS-Orb-2409Oryza barthii61.370.0 532
LLPS-Tra-2903Triticum aestivum61.340.0 537
LLPS-Vir-1620Vigna radiata61.190.0 540
LLPS-Amt-2199Amborella trichopoda60.952e-177 513
LLPS-Via-1972Vigna angularis60.950.0 536
LLPS-Brd-2360Brachypodium distachyon60.880.0 532
LLPS-Phv-0405Phaseolus vulgaris60.710.0 536
LLPS-Sol-2459Solanum lycopersicum60.50.0 548
LLPS-Mua-0127Musa acuminata60.50.0 530
LLPS-Ori-0464Oryza indica60.140.0 532
LLPS-Abg-1763Absidia glauca55.021e-159 464
LLPS-Scp-1463Schizosaccharomyces pombe54.743e-162 471
LLPS-Miv-1011Microbotryum violaceum54.693e-159 464
LLPS-Scc-0109Schizosaccharomyces cryophilus54.442e-162 472
LLPS-Mel-0588Melampsora laricipopulina54.443e-155 454
LLPS-Cym-0464Cyanidioschyzon merolae53.832e-145 429
LLPS-Crn-0994Cryptococcus neoformans53.817e-154 450
LLPS-Chc-0747Chondrus crispus53.576e-140 414
LLPS-Scj-1492Schizosaccharomyces japonicus52.846e-161 468
LLPS-Yal-0927Yarrowia lipolytica52.832e-152 446
LLPS-Spr-0335Sporisorium reilianum52.633e-154 451
LLPS-Bot-3997Bos taurus52.491e-146 432
LLPS-Usm-0054Ustilago maydis52.399e-154 450
LLPS-Gas-1383Galdieria sulphuraria52.362e-152 446
LLPS-Sus-1919Sus scrofa52.265e-146 431
LLPS-Asg-0922Ashbya gossypii52.11e-144 426
LLPS-Fec-3598Felis catus51.782e-146 432
LLPS-Fia-2442Ficedula albicollis51.785e-143 426
LLPS-Mup-3445Mustela putorius furo51.784e-146 431
LLPS-Anc-2966Anolis carolinensis51.542e-144 426
LLPS-Gaga-1964Gallus gallus51.545e-144 426
LLPS-Orl-3833Oryzias latipes51.543e-142 421
LLPS-Scf-0454Scleropages formosus51.53e-145 428
LLPS-Gaa-1243Gasterosteus aculeatus51.58e-145 428
LLPS-Mea-0780Mesocricetus auratus51.317e-145 428
LLPS-Leo-2410Lepisosteus oculatus51.278e-146 430
LLPS-Aim-0685Ailuropoda melanoleuca51.184e-145 429
LLPS-Poa-3715Pongo abelii51.076e-144 426
LLPS-Nol-0675Nomascus leucogenys51.077e-144 426
LLPS-Cas-1462Carlito syrichta51.077e-145 428
LLPS-Mod-3700Monodelphis domestica51.072e-144 427
LLPS-Pes-2532Pelodiscus sinensis51.072e-144 426
LLPS-Ran-1046Rattus norvegicus51.074e-144 426
LLPS-Orn-2937Oreochromis niloticus51.041e-143 424
LLPS-Asc-1389Aspergillus clavatus50.953e-137 407
LLPS-Kop-0984Komagataella pastoris50.942e-148 436
LLPS-Put-1310Puccinia triticina50.922e-149 439
LLPS-Scm-2202Scophthalmus maximus50.922e-142 422
LLPS-Pug-0609Puccinia graminis50.926e-151 443
LLPS-Drm-2081Drosophila melanogaster50.845e-150 441
LLPS-Cap-0471Cavia porcellus50.834e-144 426
LLPS-Cea-1553Cercocebus atys50.839e-144 425
LLPS-Chs-4116Chlorocebus sabaeus50.833e-143 424
LLPS-Icp-0440Ictalurus punctatus50.838e-143 423
LLPS-Lac-1985Latimeria chalumnae50.591e-142 422
LLPS-Asni-0729Aspergillus niger50.484e-137 407
LLPS-Sac-1612Saccharomyces cerevisiae50.471e-145 429
LLPS-Pof-4180Poecilia formosa50.462e-140 417
LLPS-Dar-0993Danio rerio50.352e-144 427
LLPS-Tar-1307Takifugu rubripes50.349e-141 417
LLPS-Meg-2327Meleagris gallopavo50.133e-129 386
LLPS-Xim-2450Xiphophorus maculatus50.129e-140 415
LLPS-Tag-2953Taeniopygia guttata49.883e-137 408
LLPS-Tum-1600Tuber melanosporum49.762e-139 413
LLPS-Asn-1158Aspergillus nidulans49.761e-134 400
LLPS-Mam-4127Macaca mulatta49.751e-130 392
LLPS-Man-1930Macaca nemestrina49.751e-130 392
LLPS-Maf-4153Macaca fascicularis49.751e-130 392
LLPS-Xet-2209Xenopus tropicalis49.643e-140 416
LLPS-Anp-3143Anas platyrhynchos49.624e-127 380
LLPS-Gog-2368Gorilla gorilla49.626e-125 379
LLPS-Otg-0311Otolemur garnettii49.543e-143 424
LLPS-Caf-0754Canis familiaris49.418e-138 410
LLPS-Myl-3796Myotis lucifugus49.411e-135 404
LLPS-Mum-3906Mus musculus49.413e-138 411
LLPS-Asm-1457Astyanax mexicanus49.312e-135 404
LLPS-Phn-1421Phaeosphaeria nodorum49.281e-140 416
LLPS-Tut-1107Tursiops truncatus49.172e-137 409
LLPS-Aon-4655Aotus nancymaae49.172e-137 409
LLPS-Nef-1284Neosartorya fischeri49.053e-134 400
LLPS-Aso-0613Aspergillus oryzae49.056e-134 399
LLPS-Asf-0713Aspergillus flavus49.056e-134 399
LLPS-Ict-0614Ictidomys tridecemlineatus48.943e-136 406
LLPS-Ova-0495Ovis aries48.944e-135 403
LLPS-Mal-3025Mandrillus leucophaeus48.944e-136 405
LLPS-Paa-0183Papio anubis48.944e-136 405
LLPS-Caj-2039Callithrix jacchus48.946e-136 405
LLPS-Asfu-1448Aspergillus fumigatus48.817e-134 399
LLPS-Loa-4079Loxodonta africana48.761e-139 416
LLPS-Rhb-1010Rhinopithecus bieti48.711e-135 404
LLPS-Eqc-3422Equus caballus48.77e-135 403
LLPS-Pat-2324Pan troglodytes48.71e-135 404
LLPS-Pap-2800Pan paniscus48.71e-135 404
LLPS-Hos-3127Homo sapiens48.72e-135 404
LLPS-Sah-2724Sarcophilus harrisii48.615e-138 410
LLPS-Pyt-1575Pyrenophora teres48.457e-134 415
LLPS-Ora-0414Ornithorhynchus anatinus48.351e-122 369
LLPS-Ast-0159Aspergillus terreus48.331e-130 390
LLPS-Nec-0687Neurospora crassa48.331e-132 396
LLPS-Blg-0813Blumeria graminis48.232e-120 364
LLPS-Lem-0930Leptosphaeria maculans48.214e-141 417
LLPS-Fud-1741Fukomys damarensis47.991e-128 386
LLPS-Pytr-1614Pyrenophora triticirepentis47.975e-138 409
LLPS-Orc-3994Oryctolagus cuniculus47.876e-129 388
LLPS-Map-1244Magnaporthe poae47.381e-129 388
LLPS-Fuo-1421Fusarium oxysporum47.371e-129 388
LLPS-Fuv-1299Fusarium verticillioides47.372e-130 390
LLPS-Dio-1426Dipodomys ordii47.097e-120 362
LLPS-Fus-0180Fusarium solani47.062e-122 369
LLPS-Ten-3754Tetraodon nigroviridis46.815e-129 388
LLPS-Cis-2011Ciona savignyi46.466e-126 379
LLPS-Mao-0966Magnaporthe oryzae46.431e-130 390
LLPS-Cogr-1261Colletotrichum graminicola46.148e-134 399
LLPS-Zyt-1548Zymoseptoria tritici46.144e-136 404
LLPS-Coo-1286Colletotrichum orbiculare46.142e-132 395
LLPS-Beb-0207Beauveria bassiana45.848e-123 370
LLPS-Gag-0205Gaeumannomyces graminis45.611e-126 380
LLPS-Dos-0332Dothistroma septosporum45.262e-131 392
LLPS-Scs-1031Sclerotinia sclerotiorum45.174e-82 263
LLPS-Trv-0769Trichoderma virens45.123e-121 366
LLPS-Urm-3150Ursus maritimus44.292e-115 353
LLPS-Cii-2325Ciona intestinalis44.052e-111 342
LLPS-Ved-0635Verticillium dahliae43.886e-114 347
LLPS-Cog-0788Colletotrichum gloeosporioides42.866e-100 313
LLPS-Cae-1517Caenorhabditis elegans42.255e-113 346
LLPS-Trr-0139Trichoderma reesei40.191e-100 313