• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Chc-0747
CHC_T00009314001

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Adenylosuccinate synthetase
Gene Name: CHC_T00009314001
Ensembl Gene: CHC_T00009314001
Ensembl Protein: CDF32632
Organism: Chondrus crispus
Taxa ID: 2769
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCDF32632CDF32632
UniProtR7Q219, R7Q219_CHOCR
GeneBankHG001531CDF32632.1
RefSeqXM_005712346.1XP_005712403.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRPPGEVLVV  LGAQWGDEGK  GKLIDLLTSQ  YDILARAAGG  ANAGHTIVVD  GVKYAFHLLP  60
61    SGLLNPHCLA  LIGNGVVLHV  PKFLSELASL  SEKGVRNVVP  RVRISDRAHL  LFDYHQIVDG  120
121   LREVERGHAK  IGTTGKGIGP  CYSSKANRTN  MRVGDLRHFR  DFPDAFRRSL  ASKHKRFHNF  180
181   DYDVRAEIAR  YYEYAQVLEP  NITDTVAELN  HAISNKEHAV  LVEGANAALL  DIDFGTYPFV  240
241   TSSNCTAGGV  ITGLGIPPTA  IDKVVGVVKA  YTTRVGQGPF  PTELHDKSGV  TLQVEGHEYG  300
301   TTTARPRRCG  WLDTFMLNYT  HSVNGYTEVC  LTKLDVLSHF  ETIKIGVGYI  VRGRKMTYYP  360
361   ASLKLLAEAE  VEYVEMPGWK  GVDIMGVRKF  EDLPENAQKY  VIQVEKLINV  PIRYVGVGPG  420
421   RDAIIYRD  428
Nucleotide CDS Sequence (FASTA)
1     ATGCGCCCGC  CGGGCGAGGT  TCTCGTCGTC  CTGGGTGCGC  AGTGGGGCGA  CGAAGGCAAA  60
61    GGCAAGCTCA  TCGACCTGCT  CACGTCGCAG  TACGACATCC  TGGCCCGCGC  TGCGGGCGGT  120
121   GCCAACGCCG  GCCACACCAT  TGTCGTCGAC  GGCGTCAAGT  ACGCGTTCCA  TCTCCTTCCC  180
181   TCGGGCCTGC  TCAATCCGCA  CTGCCTGGCC  CTCATCGGCA  ACGGCGTCGT  CCTCCACGTC  240
241   CCCAAGTTCC  TCTCCGAGCT  CGCCTCCCTC  TCGGAGAAGG  GCGTGCGCAA  CGTCGTCCCG  300
301   CGCGTCAGGA  TTTCGGACCG  CGCGCATCTG  CTGTTTGACT  ACCACCAGAT  TGTCGACGGA  360
361   TTGCGCGAGG  TCGAGAGGGG  GCACGCCAAG  ATCGGCACCA  CCGGCAAGGG  CATCGGCCCG  420
421   TGTTACTCGT  CCAAAGCGAA  CCGCACCAAC  ATGCGTGTCG  GTGACTTGCG  CCACTTTAGA  480
481   GACTTTCCGG  ACGCTTTTCG  CCGCTCGCTC  GCGTCCAAGC  ACAAGCGCTT  TCACAACTTT  540
541   GATTACGACG  TTCGCGCGGA  GATTGCACGC  TATTACGAGT  ATGCGCAGGT  GCTGGAACCG  600
601   AACATCACCG  ACACCGTCGC  GGAGCTCAAC  CATGCCATTT  CGAACAAGGA  GCATGCTGTT  660
661   TTGGTGGAAG  GCGCCAATGC  AGCGTTGCTG  GACATCGATT  TTGGCACCTA  CCCCTTTGTT  720
721   ACCTCAAGTA  ATTGCACAGC  GGGCGGCGTG  ATTACCGGTC  TGGGCATTCC  GCCAACTGCC  780
781   ATAGACAAGG  TTGTCGGCGT  CGTCAAGGCC  TACACCACCC  GCGTCGGCCA  GGGGCCGTTT  840
841   CCGACCGAGC  TGCATGATAA  ATCTGGCGTC  ACGCTCCAGG  TCGAGGGACA  TGAGTATGGC  900
901   ACCACCACGG  CCCGTCCGAG  GCGTTGTGGA  TGGCTGGATA  CGTTCATGCT  CAACTATACA  960
961   CATTCTGTGA  ATGGGTATAC  CGAGGTTTGT  CTTACAAAGT  TGGATGTGCT  TTCGCATTTT  1020
1021  GAGACTATTA  AGATTGGCGT  CGGATACATT  GTTCGTGGCA  GGAAGATGAC  CTACTATCCG  1080
1081  GCATCTTTGA  AGCTACTTGC  CGAGGCAGAA  GTTGAATATG  TGGAGATGCC  AGGCTGGAAG  1140
1141  GGGGTTGACA  TCATGGGTGT  GAGAAAGTTT  GAAGACTTAC  CCGAGAACGC  ACAAAAGTAC  1200
1201  GTGATTCAGG  TTGAAAAGCT  CATCAACGTG  CCGATCCGTT  ATGTTGGCGT  CGGTCCGGGT  1260
1261  AGAGATGCAA  TCATCTACCG  CGACTGA  1287

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
GTP-binding
Ligase
Magnesium
Metal-binding
Nucleotide-binding
Purine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast stroma
Molecular Function
Adenylosuccinate synthase activity
Molecular Function
GTP binding
Molecular Function
Magnesium ion binding
Biological Process
'de novo' AMP biosynthetic process
Biological Process
Response to cadmium ion

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cym-0464Cyanidioschyzon merolae61.240.0 546
LLPS-Gas-1383Galdieria sulphuraria60.190.0 535
LLPS-Miv-1011Microbotryum violaceum56.412e-161 469
LLPS-Usm-0054Ustilago maydis55.975e-164 476
LLPS-Abg-1763Absidia glauca55.665e-170 491
LLPS-Put-1310Puccinia triticina55.057e-164 476
LLPS-Spr-0335Sporisorium reilianum55.041e-162 473
LLPS-Phv-0405Phaseolus vulgaris54.85e-160 468
LLPS-Brn-2145Brassica napus54.86e-158 462
LLPS-Vir-1620Vigna radiata54.81e-160 469
LLPS-Brr-1112Brassica rapa54.572e-155 456
LLPS-Bro-1915Brassica oleracea54.575e-156 457
LLPS-Met-2355Medicago truncatula54.573e-157 461
LLPS-Pug-0609Puccinia graminis54.363e-163 474
LLPS-Mel-0588Melampsora laricipopulina54.342e-162 472
LLPS-Via-1972Vigna angularis54.333e-158 463
LLPS-Scp-1463Schizosaccharomyces pombe54.279e-163 473
LLPS-Crn-0994Cryptococcus neoformans54.193e-154 451
LLPS-Glm-0680Glycine max54.11e-159 467
LLPS-Asg-0922Ashbya gossypii53.947e-161 468
LLPS-Art-1169Arabidopsis thaliana53.868e-153 449
LLPS-Prp-1925Prunus persica53.869e-155 454
LLPS-Hea-2379Helianthus annuus53.866e-158 463
LLPS-Arl-0264Arabidopsis lyrata53.866e-153 450
LLPS-Bot-3997Bos taurus53.779e-156 456
LLPS-Mup-3445Mustela putorius furo53.775e-154 452
LLPS-Pot-2036Populus trichocarpa53.632e-156 459
LLPS-Nia-2586Nicotiana attenuata53.632e-155 457
LLPS-Orbr-0602Oryza brachyantha53.632e-154 453
LLPS-Sot-0966Solanum tuberosum53.631e-155 457
LLPS-Osl-0169Ostreococcus lucimarinus53.576e-154 450
LLPS-Drm-2081Drosophila melanogaster53.551e-156 458
LLPS-Fec-3598Felis catus53.542e-154 452
LLPS-Ran-1046Rattus norvegicus53.546e-153 449
LLPS-Sac-1612Saccharomyces cerevisiae53.478e-166 481
LLPS-Gor-2149Gossypium raimondii53.47e-156 457
LLPS-Orr-0955Oryza rufipogon53.43e-154 453
LLPS-Dac-1813Daucus carota53.41e-157 461
LLPS-Orni-1991Oryza nivara53.41e-154 454
LLPS-Orgl-2078Oryza glumaepatula53.46e-154 452
LLPS-Cus-1099Cucumis sativus53.47e-156 457
LLPS-Sus-1919Sus scrofa53.31e-153 450
LLPS-Scj-1492Schizosaccharomyces japonicus53.212e-158 462
LLPS-Gaga-1964Gallus gallus53.186e-156 456
LLPS-Viv-2237Vitis vinifera53.162e-156 459
LLPS-Chr-1273Chlamydomonas reinhardtii53.162e-149 440
LLPS-Otg-0311Otolemur garnettii53.074e-153 449
LLPS-Cap-0471Cavia porcellus53.076e-152 446
LLPS-Poa-3715Pongo abelii53.073e-153 449
LLPS-Nol-0675Nomascus leucogenys53.073e-153 449
LLPS-Cas-1462Carlito syrichta53.076e-153 449
LLPS-Scf-0454Scleropages formosus53.071e-156 457
LLPS-Aim-0685Ailuropoda melanoleuca53.071e-154 453
LLPS-Fia-2442Ficedula albicollis52.942e-153 453
LLPS-Mae-0815Manihot esculenta52.932e-153 451
LLPS-Coc-1423Corchorus capsularis52.931e-154 454
LLPS-Php-1841Physcomitrella patens52.936e-154 453
LLPS-Cea-1553Cercocebus atys52.836e-153 449
LLPS-Chs-4116Chlorocebus sabaeus52.832e-152 447
LLPS-Hov-1464Hordeum vulgare52.88e-152 447
LLPS-Leo-2410Lepisosteus oculatus52.721e-154 452
LLPS-Mea-0780Mesocricetus auratus52.722e-152 447
LLPS-Xet-2209Xenopus tropicalis52.715e-154 451
LLPS-Thc-1009Theobroma cacao52.692e-153 451
LLPS-Sei-2295Setaria italica52.693e-155 456
LLPS-Mua-0127Musa acuminata52.62e-154 454
LLPS-Pes-2532Pelodiscus sinensis52.593e-153 449
LLPS-Tar-1307Takifugu rubripes52.598e-152 446
LLPS-Lep-2353Leersia perrieri52.466e-155 455
LLPS-Orn-2937Oreochromis niloticus52.362e-153 449
LLPS-Anc-2966Anolis carolinensis52.365e-152 446
LLPS-Orl-3833Oryzias latipes52.368e-152 446
LLPS-Asm-1457Astyanax mexicanus52.246e-145 428
LLPS-Sob-1512Sorghum bicolor52.221e-155 457
LLPS-Brd-2360Brachypodium distachyon52.228e-153 450
LLPS-Sol-2459Solanum lycopersicum52.156e-145 447
LLPS-Gaa-1243Gasterosteus aculeatus52.125e-152 446
LLPS-Ors-1970Oryza sativa52.15e-154 452
LLPS-Tum-1600Tuber melanosporum52.057e-143 422
LLPS-Orp-0898Oryza punctata51.992e-154 454
LLPS-Zem-0333Zea mays51.994e-155 455
LLPS-Tra-2903Triticum aestivum51.992e-154 454
LLPS-Lem-0930Leptosphaeria maculans51.97e-145 427
LLPS-Scm-2202Scophthalmus maximus51.893e-151 445
LLPS-Yal-0927Yarrowia lipolytica51.883e-152 446
LLPS-Org-1697Oryza glaberrima51.872e-154 452
LLPS-Orb-2409Oryza barthii51.872e-153 451
LLPS-Amt-2199Amborella trichopoda51.853e-148 438
LLPS-Gog-2368Gorilla gorilla51.793e-134 402
LLPS-Anp-3143Anas platyrhynchos51.773e-136 404
LLPS-Mod-3700Monodelphis domestica51.772e-150 442
LLPS-Pof-4180Poecilia formosa51.763e-146 432
LLPS-Dar-0993Danio rerio51.653e-150 442
LLPS-Xim-2450Xiphophorus maculatus51.656e-148 436
LLPS-Asn-1158Aspergillus nidulans51.645e-147 432
LLPS-Meg-2327Meleagris gallopavo51.631e-139 412
LLPS-Icp-0440Ictalurus punctatus51.622e-152 447
LLPS-Sem-0453Selaginella moellendorffii51.522e-151 446
LLPS-Lac-1985Latimeria chalumnae51.292e-151 444
LLPS-Kop-0984Komagataella pastoris51.291e-153 449
LLPS-Nec-0687Neurospora crassa51.184e-146 430
LLPS-Blg-0813Blumeria graminis51.171e-129 388
LLPS-Ori-0464Oryza indica51.122e-149 442
LLPS-Pyt-1575Pyrenophora teres50.943e-137 424
LLPS-Man-1930Macaca nemestrina50.721e-137 410
LLPS-Mam-4127Macaca mulatta50.721e-137 410
LLPS-Maf-4153Macaca fascicularis50.721e-137 410
LLPS-Pytr-1614Pyrenophora triticirepentis50.718e-142 419
LLPS-Cis-2011Ciona savignyi50.597e-148 436
LLPS-Asni-0729Aspergillus niger50.595e-143 422
LLPS-Tag-2953Taeniopygia guttata50.581e-142 422
LLPS-Phn-1421Phaeosphaeria nodorum50.472e-142 421
LLPS-Cae-1517Caenorhabditis elegans50.473e-136 406
LLPS-Caf-0754Canis familiaris50.462e-145 429
LLPS-Aon-4655Aotus nancymaae50.463e-145 429
LLPS-Asfu-1448Aspergillus fumigatus50.353e-144 425
LLPS-Asc-1389Aspergillus clavatus50.353e-144 425
LLPS-Aso-0613Aspergillus oryzae50.358e-144 424
LLPS-Asf-0713Aspergillus flavus50.358e-144 424
LLPS-Scc-0109Schizosaccharomyces cryophilus50.246e-154 450
LLPS-Gag-0205Gaeumannomyces graminis50.248e-140 414
LLPS-Hos-3127Homo sapiens50.236e-144 426
LLPS-Pat-2324Pan troglodytes50.239e-144 425
LLPS-Pap-2800Pan paniscus50.234e-144 426
LLPS-Eqc-3422Equus caballus50.231e-143 426
LLPS-Ict-0614Ictidomys tridecemlineatus50.231e-144 427
LLPS-Sah-2724Sarcophilus harrisii50.234e-145 429
LLPS-Mum-3906Mus musculus50.231e-143 425
LLPS-Tut-1107Tursiops truncatus50.231e-144 427
LLPS-Paa-0183Papio anubis50.235e-144 426
LLPS-Mal-3025Mandrillus leucophaeus50.235e-144 426
LLPS-Nef-1284Neosartorya fischeri50.122e-145 428
LLPS-Loa-4079Loxodonta africana50.01e-147 436
LLPS-Caj-2039Callithrix jacchus50.01e-143 424
LLPS-Ova-0495Ovis aries50.01e-142 422
LLPS-Myl-3796Myotis lucifugus50.02e-142 421
LLPS-Ast-0159Aspergillus terreus49.881e-143 424
LLPS-Fud-1741Fukomys damarensis49.772e-140 416
LLPS-Map-1244Magnaporthe poae49.766e-139 412
LLPS-Mao-0966Magnaporthe oryzae49.768e-140 414
LLPS-Rhb-1010Rhinopithecus bieti49.546e-143 423
LLPS-Ora-0414Ornithorhynchus anatinus49.497e-130 387
LLPS-Ten-3754Tetraodon nigroviridis49.423e-142 421
LLPS-Orc-3994Oryctolagus cuniculus49.295e-138 411
LLPS-Trv-0769Trichoderma virens49.272e-126 379
LLPS-Dio-1426Dipodomys ordii48.986e-127 380
LLPS-Fus-0180Fusarium solani48.661e-130 390
LLPS-Fuo-1421Fusarium oxysporum48.345e-142 419
LLPS-Cogr-1261Colletotrichum graminicola48.345e-133 397
LLPS-Fuv-1299Fusarium verticillioides48.347e-142 419
LLPS-Coo-1286Colletotrichum orbiculare48.111e-133 398
LLPS-Zyt-1548Zymoseptoria tritici47.993e-129 387
LLPS-Beb-0207Beauveria bassiana47.871e-133 398
LLPS-Ved-0635Verticillium dahliae47.625e-131 391
LLPS-Dos-0332Dothistroma septosporum47.296e-131 391
LLPS-Urm-3150Ursus maritimus46.883e-125 378
LLPS-Scs-1031Sclerotinia sclerotiorum46.134e-78 253
LLPS-Cii-2325Ciona intestinalis46.15e-129 387
LLPS-Trr-0139Trichoderma reesei45.693e-113 345
LLPS-Cog-0788Colletotrichum gloeosporioides43.041e-95 302