• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orr-0955
PURA

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Adenylosuccinate synthetase, chloroplastic
Gene Name: PURA
Ensembl Gene: ORUFI03G05340
Ensembl Protein: ORUFI03G05340.1
Organism: Oryza rufipogon
Taxa ID: 4529
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblORUFI03G05340.1ORUFI03G05340.1
UniProtA0A0E0NQE7, A0A0E0NQE7_ORYRU

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSLSTVNHAA  AAAAAAAAGS  GKSFSAAAPA  APSVRLPRTR  APAAAAVSAA  AVGADRAADR  60
61    VSALSQVSGV  LGSQWGDEGK  GKLVDVLAPR  FDIVARCQGG  ANAGHTIYNS  EGKKFALHLV  120
121   PSGILHEGTL  CVVGNGAVIH  VPGFFNEIDG  LESNGVNCNG  RILVSDRAHL  LFDLHQAVDG  180
181   LREAELANSF  IGTTKRGIGP  CYSSKVTRNG  LRVCDLRHMD  TFGDKLDVLF  KDAASRFEGF  240
241   EYSKSMLREE  VERYKRFAER  LEPFIADTVH  VLNESIQQKK  KILVEGGQAT  MLDIDFGTYP  300
301   FVTSSSPSAG  GICTGLGIAP  RCIGDLIGVV  KAYTTRVGSG  PFPTELFGEE  GDLLRKSGME  360
361   FGTTTGRPRR  CGWLDIVALK  YCCEINGFSS  LNLTKLDVLS  GLPEVKLGVS  YNQPDGQKLQ  420
421   SFPGDLDTLE  QVQVKYEVLP  GWQSDISSVR  SYSELPLAAQ  RYVERIEELV  GVPVHYIGVG  480
481   PGRDALIYK  489
Nucleotide CDS Sequence (FASTA)
1     ATGTCGCTCT  CCACTGTCAA  CCACGCCGCC  GCCGCCGCCG  CCGCCGCCGC  AGCGGGGTCG  60
61    GGGAAATCCT  TCTCCGCGGC  TGCGCCTGCG  GCGCCATCGG  TGCGCCTGCC  AAGGACACGG  120
121   GCTCCTGCTG  CCGCCGCGGT  GTCCGCGGCG  GCTGTGGGGG  CGGACCGCGC  GGCGGACAGG  180
181   GTGTCGGCGC  TGAGCCAGGT  CTCCGGGGTG  CTGGGGTCGC  AGTGGGGCGA  CGAGGGGAAG  240
241   GGGAAGCTCG  TCGACGTGCT  CGCCCCTCGC  TTCGACATCG  TCGCGCGTTG  CCAGGGCGGA  300
301   GCAAATGCTG  GACACACCAT  TTACAATTCT  GAAGGAAAGA  AATTTGCTCT  TCATCTTGTT  360
361   CCATCTGGTA  TTCTCCATGA  AGGAACGCTG  TGTGTTGTTG  GCAATGGAGC  GGTGATCCAT  420
421   GTTCCAGGAT  TTTTTAATGA  AATTGATGGT  CTTGAATCCA  ATGGAGTCAA  TTGCAATGGA  480
481   AGAATATTGG  TCTCTGACCG  GGCACATTTA  CTCTTTGATC  TGCATCAGGC  TGTAGATGGA  540
541   CTTAGGGAAG  CAGAGCTTGC  TAATTCCTTT  ATAGGGACGA  CTAAGAGAGG  CATTGGACCA  600
601   TGTTATTCCA  GCAAGGTCAC  TCGAAACGGA  CTGCGAGTCT  GTGATCTAAG  GCACATGGAC  660
661   ACTTTTGGGG  ATAAGCTTGA  TGTCTTGTTT  AAAGATGCCG  CTTCAAGGTT  TGAAGGCTTT  720
721   GAGTACAGCA  AAAGCATGCT  CAGGGAGGAG  GTTGAGAGGT  ACAAAAGATT  TGCAGAGCGC  780
781   TTGGAGCCGT  TCATTGCTGA  TACTGTTCAT  GTGTTGAATG  AATCTATCCA  ACAGAAGAAG  840
841   AAAATTCTGG  TTGAAGGTGG  TCAAGCAACA  ATGTTGGATA  TTGATTTTGG  AACTTACCCA  900
901   TTTGTGACTT  CTTCTAGCCC  TTCAGCTGGT  GGGATATGCA  CTGGCCTTGG  GATTGCCCCA  960
961   AGGTGTATTG  GTGACCTGAT  TGGAGTGGTA  AAAGCTTATA  CAACAAGGGT  TGGTTCTGGG  1020
1021  CCTTTTCCAA  CTGAACTGTT  TGGAGAGGAA  GGTGATCTCC  TTAGGAAATC  AGGAATGGAA  1080
1081  TTTGGGACGA  CAACAGGCCG  CCCAAGGCGT  TGTGGCTGGC  TTGACATTGT  TGCACTAAAG  1140
1141  TACTGCTGCG  AGATAAATGG  GTTTTCATCT  CTTAATCTGA  CCAAACTTGA  TGTTCTGTCT  1200
1201  GGATTACCAG  AAGTTAAGCT  GGGGGTTTCT  TATAACCAAC  CTGATGGGCA  GAAGCTACAA  1260
1261  TCCTTCCCAG  GGGATCTTGA  TACTCTGGAG  CAAGTACAGG  TCAAATATGA  GGTGTTGCCT  1320
1321  GGGTGGCAAA  GTGACATTTC  GTCTGTCCGG  AGTTACAGTG  AACTTCCCCT  AGCTGCCCAA  1380
1381  CGCTATGTCG  AGAGGATAGA  AGAGCTCGTT  GGTGTTCCAG  TCCACTACAT  TGGTGTTGGA  1440
1441  CCTGGGAGGG  ATGCTCTAAT  ATACAAGTAA  1470

▼ KEYWORD

ID
Family
Chloroplast
Complete proteome
GTP-binding
Ligase
Magnesium
Metal-binding
Nucleotide-binding
Plastid
Purine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Apoplast
Cellular Component
Chloroplast stroma
Molecular Function
Adenylosuccinate synthase activity
Molecular Function
GTP binding
Molecular Function
Magnesium ion binding
Biological Process
'de novo' AMP biosynthetic process
Biological Process
Response to cadmium ion

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orni-1991Oryza nivara97.140.0 874
LLPS-Orgl-2078Oryza glumaepatula96.930.0 875
LLPS-Hov-1464Hordeum vulgare94.610.0 827
LLPS-Ori-0464Oryza indica93.310.0 862
LLPS-Orbr-0602Oryza brachyantha93.250.0 862
LLPS-Coc-1423Corchorus capsularis83.80.0 748
LLPS-Mae-0815Manihot esculenta83.10.0 744
LLPS-Thc-1009Theobroma cacao82.860.0 742
LLPS-Brd-2360Brachypodium distachyon82.860.0 737
LLPS-Orp-0898Oryza punctata82.630.0 744
LLPS-Ors-1970Oryza sativa82.630.0 743
LLPS-Nia-2586Nicotiana attenuata82.630.0 742
LLPS-Orb-2409Oryza barthii82.390.0 741
LLPS-Hea-2379Helianthus annuus82.390.0 734
LLPS-Tra-2903Triticum aestivum82.390.0 743
LLPS-Sob-1512Sorghum bicolor82.390.0 744
LLPS-Org-1697Oryza glaberrima82.390.0 743
LLPS-Zem-0333Zea mays82.390.0 741
LLPS-Pot-2036Populus trichocarpa82.160.0 736
LLPS-Lep-2353Leersia perrieri81.920.0 741
LLPS-Sei-2295Setaria italica81.920.0 737
LLPS-Dac-1813Daucus carota81.690.0 739
LLPS-Sot-0966Solanum tuberosum81.690.0 739
LLPS-Vir-1620Vigna radiata81.220.0 723
LLPS-Prp-1925Prunus persica81.220.0 728
LLPS-Via-1972Vigna angularis80.990.0 719
LLPS-Viv-2237Vitis vinifera80.990.0 723
LLPS-Gor-2149Gossypium raimondii80.990.0 724
LLPS-Glm-0680Glycine max80.750.0 720
LLPS-Phv-0405Phaseolus vulgaris80.750.0 720
LLPS-Arl-0264Arabidopsis lyrata80.520.0 717
LLPS-Mua-0127Musa acuminata80.320.0 734
LLPS-Art-1169Arabidopsis thaliana80.280.0 718
LLPS-Brr-1112Brassica rapa80.050.0 706
LLPS-Bro-1915Brassica oleracea80.050.0 721
LLPS-Brn-2145Brassica napus79.860.0 717
LLPS-Met-2355Medicago truncatula79.580.0 696
LLPS-Sol-2459Solanum lycopersicum78.60.0 732
LLPS-Cus-1099Cucumis sativus78.170.0 706
LLPS-Amt-2199Amborella trichopoda76.060.0 675
LLPS-Php-1841Physcomitrella patens74.180.0 684
LLPS-Sem-0453Selaginella moellendorffii69.720.0 635
LLPS-Osl-0169Ostreococcus lucimarinus63.330.0 571
LLPS-Chr-1273Chlamydomonas reinhardtii62.760.0 557
LLPS-Gas-1383Galdieria sulphuraria56.341e-168 490
LLPS-Spr-0335Sporisorium reilianum55.562e-162 474
LLPS-Cym-0464Cyanidioschyzon merolae55.326e-154 453
LLPS-Usm-0054Ustilago maydis55.083e-162 474
LLPS-Miv-1011Microbotryum violaceum53.972e-159 467
LLPS-Asg-0922Ashbya gossypii53.465e-149 440
LLPS-Chc-0747Chondrus crispus53.43e-146 433
LLPS-Crn-0994Cryptococcus neoformans53.323e-152 448
LLPS-Phn-1421Phaeosphaeria nodorum52.121e-152 449
LLPS-Put-1310Puccinia triticina52.051e-150 444
LLPS-Scp-1463Schizosaccharomyces pombe52.011e-159 467
LLPS-Sac-1612Saccharomyces cerevisiae51.842e-152 449
LLPS-Mel-0588Melampsora laricipopulina51.728e-152 447
LLPS-Pug-0609Puccinia graminis51.63e-151 446
LLPS-Drm-2081Drosophila melanogaster51.533e-152 449
LLPS-Mup-3445Mustela putorius furo51.521e-148 440
LLPS-Cap-0471Cavia porcellus51.522e-148 440
LLPS-Sus-1919Sus scrofa51.284e-147 436
LLPS-Mea-0780Mesocricetus auratus51.282e-147 437
LLPS-Ran-1046Rattus norvegicus51.283e-147 436
LLPS-Poa-3715Pongo abelii51.282e-147 437
LLPS-Nol-0675Nomascus leucogenys51.282e-147 437
LLPS-Cas-1462Carlito syrichta51.284e-148 439
LLPS-Aim-0685Ailuropoda melanoleuca51.167e-147 436
LLPS-Orl-3833Oryzias latipes51.156e-148 438
LLPS-Orn-2937Oreochromis niloticus51.151e-148 440
LLPS-Scj-1492Schizosaccharomyces japonicus51.063e-159 466
LLPS-Cea-1553Cercocebus atys51.053e-147 436
LLPS-Yal-0927Yarrowia lipolytica51.058e-151 444
LLPS-Chs-4116Chlorocebus sabaeus51.057e-147 436
LLPS-Otg-0311Otolemur garnettii51.053e-146 434
LLPS-Tag-2953Taeniopygia guttata50.931e-144 429
LLPS-Kop-0984Komagataella pastoris50.822e-151 446
LLPS-Fec-3598Felis catus50.822e-147 437
LLPS-Pof-4180Poecilia formosa50.82e-144 429
LLPS-Abg-1763Absidia glauca50.717e-154 452
LLPS-Tum-1600Tuber melanosporum50.712e-147 435
LLPS-Xim-2450Xiphophorus maculatus50.691e-144 430
LLPS-Lem-0930Leptosphaeria maculans50.592e-146 433
LLPS-Bot-3997Bos taurus50.587e-147 436
LLPS-Tar-1307Takifugu rubripes50.585e-146 433
LLPS-Gaa-1243Gasterosteus aculeatus50.461e-145 432
LLPS-Aon-4655Aotus nancymaae50.351e-143 427
LLPS-Mum-3906Mus musculus50.352e-144 429
LLPS-Scc-0109Schizosaccharomyces cryophilus50.358e-158 462
LLPS-Tut-1107Tursiops truncatus50.351e-143 427
LLPS-Fia-2442Ficedula albicollis50.356e-144 431
LLPS-Caf-0754Canis familiaris50.353e-143 426
LLPS-Maf-4153Macaca fascicularis50.124e-136 408
LLPS-Mal-3025Mandrillus leucophaeus50.122e-142 424
LLPS-Paa-0183Papio anubis50.122e-142 424
LLPS-Zyt-1548Zymoseptoria tritici50.122e-140 418
LLPS-Ova-0495Ovis aries50.123e-141 421
LLPS-Myl-3796Myotis lucifugus50.123e-141 421
LLPS-Man-1930Macaca nemestrina50.124e-136 408
LLPS-Dar-0993Danio rerio50.123e-145 431
LLPS-Mam-4127Macaca mulatta50.124e-136 408
LLPS-Anc-2966Anolis carolinensis50.122e-144 429
LLPS-Ict-0614Ictidomys tridecemlineatus50.122e-142 424
LLPS-Gaga-1964Gallus gallus50.121e-145 432
LLPS-Gog-2368Gorilla gorilla50.01e-127 387
LLPS-Pyt-1575Pyrenophora teres50.03e-139 432
LLPS-Scm-2202Scophthalmus maximus50.07e-146 434
LLPS-Leo-2410Lepisosteus oculatus49.881e-145 432
LLPS-Sah-2724Sarcophilus harrisii49.881e-142 425
LLPS-Caj-2039Callithrix jacchus49.886e-142 423
LLPS-Hos-3127Homo sapiens49.887e-142 422
LLPS-Pat-2324Pan troglodytes49.888e-142 422
LLPS-Pap-2800Pan paniscus49.884e-142 423
LLPS-Mod-3700Monodelphis domestica49.885e-145 431
LLPS-Pes-2532Pelodiscus sinensis49.881e-144 429
LLPS-Eqc-3422Equus caballus49.883e-140 419
LLPS-Pytr-1614Pyrenophora triticirepentis49.655e-144 427
LLPS-Xet-2209Xenopus tropicalis49.654e-144 428
LLPS-Scf-0454Scleropages formosus49.538e-146 432
LLPS-Lac-1985Latimeria chalumnae49.429e-145 430
LLPS-Rhb-1010Rhinopithecus bieti49.421e-140 420
LLPS-Ten-3754Tetraodon nigroviridis49.423e-141 421
LLPS-Asni-0729Aspergillus niger49.292e-133 400
LLPS-Dio-1426Dipodomys ordii49.255e-129 388
LLPS-Icp-0440Ictalurus punctatus49.182e-143 427
LLPS-Orc-3994Oryctolagus cuniculus49.188e-135 405
LLPS-Meg-2327Meleagris gallopavo49.04e-131 393
LLPS-Mao-0966Magnaporthe oryzae48.826e-135 404
LLPS-Anp-3143Anas platyrhynchos48.754e-129 388
LLPS-Coo-1286Colletotrichum orbiculare48.66e-139 414
LLPS-Blg-0813Blumeria graminis48.591e-130 393
LLPS-Nec-0687Neurospora crassa48.584e-138 412
LLPS-Asm-1457Astyanax mexicanus48.511e-139 417
LLPS-Fud-1741Fukomys damarensis48.498e-136 407
LLPS-Aso-0613Aspergillus oryzae48.364e-132 396
LLPS-Asf-0713Aspergillus flavus48.364e-132 396
LLPS-Asc-1389Aspergillus clavatus48.351e-131 395
LLPS-Nef-1284Neosartorya fischeri48.352e-133 400
LLPS-Loa-4079Loxodonta africana48.121e-141 423
LLPS-Dos-0332Dothistroma septosporum48.112e-138 412
LLPS-Map-1244Magnaporthe poae48.13e-133 399
LLPS-Ora-0414Ornithorhynchus anatinus47.996e-124 375
LLPS-Cogr-1261Colletotrichum graminicola47.93e-139 415
LLPS-Gag-0205Gaeumannomyces graminis47.876e-133 399
LLPS-Cis-2011Ciona savignyi47.692e-133 401
LLPS-Asfu-1448Aspergillus fumigatus47.642e-131 395
LLPS-Asn-1158Aspergillus nidulans47.412e-131 395
LLPS-Ast-0159Aspergillus terreus47.412e-128 387
LLPS-Scs-1031Sclerotinia sclerotiorum46.831e-92 292
LLPS-Fuv-1299Fusarium verticillioides46.822e-130 392
LLPS-Fuo-1421Fusarium oxysporum46.351e-127 385
LLPS-Beb-0207Beauveria bassiana46.12e-129 390
LLPS-Fus-0180Fusarium solani46.13e-124 376
LLPS-Cii-2325Ciona intestinalis45.671e-118 362
LLPS-Trv-0769Trichoderma virens44.666e-127 383
LLPS-Cae-1517Caenorhabditis elegans44.577e-122 371
LLPS-Urm-3150Ursus maritimus44.291e-116 358
LLPS-Cog-0788Colletotrichum gloeosporioides44.222e-103 324
LLPS-Ved-0635Verticillium dahliae44.211e-120 367
LLPS-Trr-0139Trichoderma reesei41.537e-109 337