• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xet-2986
vbp1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Prefoldin subunit 3
Gene Name: vbp1, LOC100145749
Ensembl Gene: ENSXETG00000001529.3
Ensembl Protein: ENSXETP00000003195.3
Organism: Xenopus tropicalis
Taxa ID: 8364
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAVTSEGAGV  AGLKRTHLGI  PEAVFVEDVD  AFMKKPGNET  ADAVLKKLDE  QYQKYKFMEL  60
61    NLTQKKRRLK  SQIPEIKQTL  EILKHMQKKK  DTTEPMKTRF  LLADNLYCKA  SVPPTDKVCL  120
121   WLGANVMLEY  DIDEAQALLE  KNLSTATRNL  DSTEEDLDFL  RDQFTTTEVN  MARVYNWDVK  180
181   RRNKDDPSKS  KA  192
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGTGA  CCAGTGAGGG  AGCCGGTGTT  GCTGGACTGA  AACGGACTCA  TTTGGGAATT  60
61    CCGGAGGCAG  TGTTTGTGGA  AGATGTAGAT  GCTTTTATGA  AGAAACCTGG  AAATGAGACA  120
121   GCAGATGCAG  TACTCAAGAA  ACTGGATGAG  CAGTATCAGA  AATATAAATT  TATGGAACTT  180
181   AATTTGACCC  AGAAAAAAAG  AAGGCTAAAG  AGCCAGATTC  CAGAAATTAA  GCAGACCTTA  240
241   GAAATTTTAA  AACACATGCA  GAAGAAAAAG  GATACTACTG  AACCAATGAA  AACTAGGTTT  300
301   CTGCTAGCCG  ATAATCTGTA  CTGTAAAGCA  TCTGTGCCAC  CTACAGACAA  AGTCTGCCTG  360
361   TGGTTGGGGG  CAAATGTTAT  GCTTGAGTAC  GATATTGATG  AAGCTCAGGC  TTTACTTGAA  420
421   AAGAATCTTT  CAACTGCTAC  AAGAAACCTT  GATTCTACAG  AAGAAGACCT  CGACTTCCTT  480
481   AGGGACCAGT  TCACTACTAC  AGAAGTCAAT  ATGGCTAGAG  TTTATAATTG  GGATGTAAAA  540
541   AGAAGAAACA  AAGACGATCC  TTCAAAAAGC  AAAGCATAA  579

▼ KEYWORD

ID
Family
Chaperone
Coiled coil
Complete proteome
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Polysome
Cellular Component
Prefoldin complex
Molecular Function
Tubulin binding
Biological Process
Microtubule-based process
Biological Process
Protein folding
Biological Process
Tubulin complex assembly

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pes-3587Pelodiscus sinensis92.773e-111 322
LLPS-Gaga-3288Gallus gallus92.53e-106 309
LLPS-Ora-3123Ornithorhynchus anatinus91.723e-93 275
LLPS-Meg-1915Meleagris gallopavo91.673e-111 322
LLPS-Tag-2291Taeniopygia guttata91.061e-117 339
LLPS-Fia-2828Ficedula albicollis90.51e-116 338
LLPS-Urm-1628Ursus maritimus90.08e-103 300
LLPS-Cea-2219Cercocebus atys89.942e-116 338
LLPS-Paa-4142Papio anubis89.942e-116 337
LLPS-Anc-3584Anolis carolinensis88.489e-123 352
LLPS-Chs-1240Chlorocebus sabaeus87.851e-113 331
LLPS-Lac-1705Latimeria chalumnae87.52e-122 351
LLPS-Tut-1608Tursiops truncatus86.398e-118 340
LLPS-Otg-0664Otolemur garnettii86.231e-101 298
LLPS-Leo-1983Lepisosteus oculatus85.865e-118 340
LLPS-Mea-1808Mesocricetus auratus84.262e-119 344
LLPS-Cap-2047Cavia porcellus84.265e-119 343
LLPS-Mum-4073Mus musculus84.181e-118 342
LLPS-Ict-3866Ictidomys tridecemlineatus84.189e-119 342
LLPS-Dar-3929Danio rerio83.771e-114 332
LLPS-Caj-3724Callithrix jacchus83.761e-118 342
LLPS-Aon-4066Aotus nancymaae83.437e-107 311
LLPS-Sus-1203Sus scrofa83.257e-117 338
LLPS-Maf-1328Macaca fascicularis83.253e-117 338
LLPS-Gog-1861Gorilla gorilla83.253e-117 338
LLPS-Bot-3970Bos taurus83.258e-118 340
LLPS-Ova-1562Ovis aries83.258e-118 340
LLPS-Mal-1787Mandrillus leucophaeus83.253e-117 338
LLPS-Man-3236Macaca nemestrina83.253e-117 338
LLPS-Hos-0555Homo sapiens83.253e-117 338
LLPS-Pat-3142Pan troglodytes83.253e-117 338
LLPS-Pap-1643Pan paniscus83.253e-117 338
LLPS-Mam-4616Macaca mulatta83.253e-117 338
LLPS-Poa-3596Pongo abelii83.253e-117 338
LLPS-Caf-3695Canis familiaris83.258e-118 340
LLPS-Nol-2834Nomascus leucogenys83.253e-117 338
LLPS-Orc-3626Oryctolagus cuniculus83.084e-116 337
LLPS-Mup-2383Mustela putorius furo82.742e-117 338
LLPS-Fec-2707Felis catus82.743e-117 338
LLPS-Eqc-0808Equus caballus82.743e-117 338
LLPS-Anp-0765Anas platyrhynchos82.381e-111 324
LLPS-Loa-3569Loxodonta africana82.329e-116 335
LLPS-Asm-4015Astyanax mexicanus82.252e-100 296
LLPS-Cas-1705Carlito syrichta82.231e-115 334
LLPS-Fud-0979Fukomys damarensis81.735e-115 333
LLPS-Orn-0484Oreochromis niloticus81.483e-114 330
LLPS-Myl-2125Myotis lucifugus81.412e-114 331
LLPS-Gaa-2723Gasterosteus aculeatus80.759e-111 322
LLPS-Icp-2754Ictalurus punctatus80.639e-112 324
LLPS-Aim-2086Ailuropoda melanoleuca80.31e-110 321
LLPS-Scf-2814Scleropages formosus79.267e-110 319
LLPS-Sah-0547Sarcophilus harrisii78.972e-109 318
LLPS-Orl-4003Oryzias latipes78.531e-108 316
LLPS-Dio-3278Dipodomys ordii78.178e-104 304
LLPS-Pof-2098Poecilia formosa77.048e-107 312
LLPS-Ran-1786Rattus norvegicus75.715e-94 279
LLPS-Rhb-1684Rhinopithecus bieti69.063e-79 241
LLPS-Tar-3876Takifugu rubripes67.383e-88 265
LLPS-Abg-1477Absidia glauca64.295e-1571.6
LLPS-Ten-3499Tetraodon nigroviridis61.93e-80 244
LLPS-Cii-2299Ciona intestinalis58.935e-69 215
LLPS-Drm-1995Drosophila melanogaster55.622e-63 201
LLPS-Vir-1351Vigna radiata49.563e-34 125
LLPS-Cog-0986Colletotrichum gloeosporioides49.418e-50 166
LLPS-Org-2046Oryza glaberrima49.231e-38 135
LLPS-Sem-0857Selaginella moellendorffii49.142e-43 150
LLPS-Ved-1479Verticillium dahliae49.18e-49 164
LLPS-Orb-0811Oryza barthii48.841e-37 134
LLPS-Ori-0913Oryza indica48.785e-35 126
LLPS-Asni-0269Aspergillus niger48.536e-39 137
LLPS-Pyt-1157Pyrenophora teres48.57e-50 166
LLPS-Pytr-1493Pyrenophora triticirepentis48.54e-50 167
LLPS-Map-1409Magnaporthe poae48.456e-47 159
LLPS-Fuo-1015Fusarium oxysporum48.453e-45 155
LLPS-Fuv-1435Fusarium verticillioides48.176e-46 156
LLPS-Sob-2237Sorghum bicolor48.173e-49 165
LLPS-Fus-0565Fusarium solani47.856e-44 151
LLPS-Spr-1570Sporisorium reilianum47.754e-51 170
LLPS-Amt-1737Amborella trichopoda47.672e-50 167
LLPS-Met-0886Medicago truncatula47.563e-47 159
LLPS-Usm-0924Ustilago maydis47.542e-50 176
LLPS-Mao-1533Magnaporthe oryzae47.318e-48 162
LLPS-Coo-1605Colletotrichum orbiculare47.222e-50 168
LLPS-Trr-0547Trichoderma reesei47.164e-49 165
LLPS-Miv-0992Microbotryum violaceum46.998e-43 152
LLPS-Orni-2227Oryza nivara46.957e-47 159
LLPS-Mel-0111Melampsora laricipopulina46.953e-45 154
LLPS-Orp-0301Oryza punctata46.957e-47 159
LLPS-Ors-2366Oryza sativa46.957e-47 159
LLPS-Phv-0905Phaseolus vulgaris46.957e-47 159
LLPS-Orr-1408Oryza rufipogon46.957e-47 159
LLPS-Zem-1881Zea mays46.784e-49 164
LLPS-Phn-1075Phaeosphaeria nodorum46.714e-47 159
LLPS-Php-0576Physcomitrella patens46.637e-48 161
LLPS-Cus-2068Cucumis sativus46.391e-44 153
LLPS-Lep-0908Leersia perrieri46.343e-46 157
LLPS-Via-0512Vigna angularis46.341e-46 158
LLPS-Sei-1912Setaria italica46.22e-48 162
LLPS-Cogr-0992Colletotrichum graminicola46.078e-49 164
LLPS-Yal-1149Yarrowia lipolytica46.013e-41 144
LLPS-Dos-0857Dothistroma septosporum45.985e-45 154
LLPS-Orbr-1007Oryza brachyantha45.936e-47 159
LLPS-Aso-0699Aspergillus oryzae45.888e-43 148
LLPS-Glm-1736Glycine max45.732e-46 157
LLPS-Viv-1946Vitis vinifera45.733e-47 159
LLPS-Mua-2169Musa acuminata45.611e-48 163
LLPS-Sol-1091Solanum lycopersicum45.532e-33 122
LLPS-Blg-0858Blumeria graminis45.515e-43 148
LLPS-Beb-1276Beauveria bassiana45.452e-49 165
LLPS-Nec-0645Neurospora crassa45.45e-47 161
LLPS-Gag-0855Gaeumannomyces graminis45.352e-46 158
LLPS-Kop-0010Komagataella pastoris45.298e-39 137
LLPS-Thc-2491Theobroma cacao45.121e-45 155
LLPS-Gor-2541Gossypium raimondii45.127e-45 154
LLPS-Coc-0266Corchorus capsularis45.126e-46 156
LLPS-Prp-1329Prunus persica45.031e-47 160
LLPS-Trv-0702Trichoderma virens45.03e-47 160
LLPS-Zyt-1479Zymoseptoria tritici44.913e-42 147
LLPS-Nia-1893Nicotiana attenuata44.918e-46 155
LLPS-Scc-1473Schizosaccharomyces cryophilus44.727e-36 129
LLPS-Pot-2704Populus trichocarpa44.572e-46 157
LLPS-Asn-0121Aspergillus nidulans44.442e-43 150
LLPS-Asg-1536Ashbya gossypii44.311e-38 137
LLPS-Orm-0296Oryza meridionalis44.253e-43 150
LLPS-Tra-1573Triticum aestivum44.196e-45 154
LLPS-Orgl-2052Oryza glumaepatula44.165e-39 138
LLPS-Asc-1694Aspergillus clavatus44.126e-43 149
LLPS-Ast-0256Aspergillus terreus44.124e-42 146
LLPS-Mae-0299Manihot esculenta44.04e-46 156
LLPS-Pug-0444Puccinia graminis43.94e-43 149
LLPS-Art-2479Arabidopsis thaliana43.91e-44 153
LLPS-Brd-0484Brachypodium distachyon43.63e-44 152
LLPS-Hov-0114Hordeum vulgare43.537e-46 156
LLPS-Sac-1216Saccharomyces cerevisiae43.353e-37 134
LLPS-Arl-0722Arabidopsis lyrata43.293e-44 152
LLPS-Nef-1475Neosartorya fischeri43.274e-42 147
LLPS-Scj-1452Schizosaccharomyces japonicus42.861e-33 124
LLPS-Scp-1429Schizosaccharomyces pombe42.776e-34 124
LLPS-Put-1327Puccinia triticina42.773e-42 147
LLPS-Hea-0170Helianthus annuus42.73e-46 157
LLPS-Sot-1061Solanum tuberosum42.682e-44 152
LLPS-Asf-0688Aspergillus flavus42.673e-31 120
LLPS-Tru-1909Triticum urartu41.761e-41 145
LLPS-Brr-0133Brassica rapa41.466e-43 148
LLPS-Bro-2664Brassica oleracea41.463e-42 147
LLPS-Asfu-0489Aspergillus fumigatus41.061e-32 121
LLPS-Brn-2960Brassica napus40.912e-43 149
LLPS-Chc-0105Chondrus crispus40.882e-40 142
LLPS-Gas-0783Galdieria sulphuraria39.882e-37 134
LLPS-Cae-0436Caenorhabditis elegans39.764e-38 135
LLPS-Crn-0936Cryptococcus neoformans39.497e-40 142
LLPS-Chr-0693Chlamydomonas reinhardtii39.185e-39 138
LLPS-Osl-1071Ostreococcus lucimarinus37.582e-32 120
LLPS-Dac-1820Daucus carota36.841e-0957.8
LLPS-Tum-1438Tuber melanosporum36.793e-1882.0
LLPS-Lem-1236Leptosphaeria maculans36.284e-1676.3
LLPS-Cym-0780Cyanidioschyzon merolae33.339e-2087.8