LLPS-Ict-3866
VBP1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Prefoldin subunit 3 |
| Gene Name: | VBP1 |
| Ensembl Gene: | ENSSTOG00000006684.3 |
| Ensembl Protein: | ENSSTOP00000005969.3 |
| Organism: | Ictidomys tridecemlineatus |
| Taxa ID: | 43179 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSSTOT00000006676.3 | ENSSTOP00000005969.3 |
| UniProt | I3M8C1, I3M8C1_ICTTR | |
| GeneBank | AGTP01117769, AGTP01117767, AGTP01117768 | |
| RefSeq | XM_005342016.2 | XP_005342073.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAASKHGCGV EVAAGNGRRL HLGIPEAVFV EDVDSFMKQP GNETADTVLK KLDEQYQKYK 60 61 FMELNLAQKK RRLKGQIPEI KQTLEILKYM QKKKESTSSL ETRFLLADNL YCKASVPPTD 120 121 KVCLWLGANV MLEYDIDEAQ ALLEKNLSTA TKNLDSLEED LDFLRDQFTT TEVNMARVYN 180 181 WDVKRRNKDD STKNKA 196 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCCT CTAAGCACGG TTGCGGCGTC GAAGTGGCTG CAGGGAATGG GCGGCGGCTC 60 61 CACCTGGGGA TTCCTGAGGC TGTATTTGTG GAAGATGTAG ACTCCTTCAT GAAACAGCCT 120 121 GGGAATGAGA CTGCAGATAC AGTACTAAAG AAGCTGGATG AACAATACCA AAAGTATAAG 180 181 TTTATGGAAC TCAACCTTGC TCAAAAGAAA AGAAGGCTAA AAGGTCAGAT TCCTGAAATT 240 241 AAGCAGACTC TGGAAATTCT AAAATACATG CAGAAGAAAA AAGAGTCCAC CAGTTCACTA 300 301 GAGACCAGAT TCTTATTGGC AGATAACCTG TACTGCAAAG CTTCAGTTCC TCCTACTGAT 360 361 AAAGTTTGTC TGTGGTTGGG GGCTAATGTA ATGCTCGAAT ATGATATTGA TGAAGCTCAG 420 421 GCATTGTTGG AAAAGAATTT ATCAACTGCT ACAAAGAATC TTGATTCTCT TGAGGAAGAC 480 481 CTTGACTTTC TTCGAGATCA GTTTACTACT ACAGAAGTCA ATATGGCCAG GGTTTATAAT 540 541 TGGGATGTAA AGAGAAGAAA CAAAGACGAT TCTACCAAGA ACAAAGCGTA A 591 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Intracellular membrane-bounded organelle | |
Cellular Component | Prefoldin complex | |
Biological Process | Protein folding |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-1628 | Ursus maritimus | 100.0 | 3e-113 | 327 |
| LLPS-Bot-3970 | Bos taurus | 97.97 | 1e-138 | 392 |
| LLPS-Ova-1562 | Ovis aries | 97.97 | 1e-138 | 392 |
| LLPS-Mup-2383 | Mustela putorius furo | 97.46 | 1e-138 | 392 |
| LLPS-Sus-1203 | Sus scrofa | 97.46 | 9e-138 | 392 |
| LLPS-Eqc-0808 | Equus caballus | 96.95 | 7e-138 | 390 |
| LLPS-Mum-4073 | Mus musculus | 96.94 | 1e-139 | 395 |
| LLPS-Tut-1608 | Tursiops truncatus | 96.45 | 1e-136 | 387 |
| LLPS-Caf-3695 | Canis familiaris | 96.45 | 3e-137 | 389 |
| LLPS-Fec-2707 | Felis catus | 96.45 | 6e-137 | 388 |
| LLPS-Orc-3626 | Oryctolagus cuniculus | 96.43 | 1e-137 | 392 |
| LLPS-Otg-0664 | Otolemur garnettii | 96.36 | 9e-114 | 328 |
| LLPS-Cap-2047 | Cavia porcellus | 95.94 | 5e-137 | 389 |
| LLPS-Cas-1705 | Carlito syrichta | 95.94 | 1e-136 | 387 |
| LLPS-Loa-3569 | Loxodonta africana | 95.45 | 6e-135 | 383 |
| LLPS-Mal-1787 | Mandrillus leucophaeus | 95.43 | 8e-136 | 385 |
| LLPS-Paa-4142 | Papio anubis | 95.43 | 4e-135 | 385 |
| LLPS-Cea-2219 | Cercocebus atys | 95.43 | 4e-135 | 385 |
| LLPS-Maf-1328 | Macaca fascicularis | 95.43 | 8e-136 | 385 |
| LLPS-Gog-1861 | Gorilla gorilla | 95.43 | 2e-135 | 384 |
| LLPS-Mam-4616 | Macaca mulatta | 95.43 | 8e-136 | 385 |
| LLPS-Poa-3596 | Pongo abelii | 95.43 | 2e-135 | 384 |
| LLPS-Nol-2834 | Nomascus leucogenys | 95.43 | 2e-135 | 384 |
| LLPS-Man-3236 | Macaca nemestrina | 95.43 | 8e-136 | 385 |
| LLPS-Pat-3142 | Pan troglodytes | 95.43 | 2e-135 | 384 |
| LLPS-Pap-1643 | Pan paniscus | 95.43 | 2e-135 | 384 |
| LLPS-Hos-0555 | Homo sapiens | 95.43 | 2e-135 | 384 |
| LLPS-Mea-1808 | Mesocricetus auratus | 94.92 | 2e-136 | 387 |
| LLPS-Caj-3724 | Callithrix jacchus | 94.92 | 8e-135 | 383 |
| LLPS-Aim-2086 | Ailuropoda melanoleuca | 94.44 | 2e-131 | 374 |
| LLPS-Aon-4066 | Aotus nancymaae | 94.25 | 9e-116 | 334 |
| LLPS-Ora-3123 | Ornithorhynchus anatinus | 93.79 | 4e-95 | 280 |
| LLPS-Gaga-3288 | Gallus gallus | 93.75 | 6e-107 | 311 |
| LLPS-Chs-1240 | Chlorocebus sabaeus | 93.47 | 1e-132 | 379 |
| LLPS-Meg-1915 | Meleagris gallopavo | 93.45 | 3e-112 | 325 |
| LLPS-Fud-0979 | Fukomys damarensis | 93.4 | 2e-132 | 377 |
| LLPS-Pes-3587 | Pelodiscus sinensis | 93.37 | 8e-111 | 321 |
| LLPS-Fia-2828 | Ficedula albicollis | 91.62 | 3e-116 | 337 |
| LLPS-Tag-2291 | Taeniopygia guttata | 91.06 | 3e-116 | 336 |
| LLPS-Myl-2125 | Myotis lucifugus | 90.45 | 4e-128 | 366 |
| LLPS-Anc-3584 | Anolis carolinensis | 87.0 | 1e-123 | 354 |
| LLPS-Lac-1705 | Latimeria chalumnae | 86.89 | 1e-113 | 330 |
| LLPS-Dio-3278 | Dipodomys ordii | 85.28 | 2e-115 | 333 |
| LLPS-Xet-2986 | Xenopus tropicalis | 84.18 | 9e-119 | 342 |
| LLPS-Orn-0484 | Oreochromis niloticus | 84.18 | 2e-110 | 321 |
| LLPS-Anp-0765 | Anas platyrhynchos | 84.1 | 2e-113 | 329 |
| LLPS-Sah-0547 | Sarcophilus harrisii | 82.47 | 2e-114 | 331 |
| LLPS-Rhb-1684 | Rhinopithecus bieti | 81.71 | 6e-86 | 258 |
| LLPS-Leo-1983 | Lepisosteus oculatus | 81.44 | 2e-113 | 328 |
| LLPS-Dar-3929 | Danio rerio | 80.77 | 3e-108 | 315 |
| LLPS-Gaa-2723 | Gasterosteus aculeatus | 80.11 | 6e-107 | 312 |
| LLPS-Asm-4015 | Astyanax mexicanus | 79.75 | 2e-94 | 281 |
| LLPS-Icp-2754 | Ictalurus punctatus | 79.67 | 5e-107 | 312 |
| LLPS-Scf-2814 | Scleropages formosus | 79.56 | 5e-107 | 312 |
| LLPS-Orl-4003 | Oryzias latipes | 79.12 | 8e-106 | 309 |
| LLPS-Ran-1786 | Rattus norvegicus | 78.33 | 6e-102 | 299 |
| LLPS-Pof-2098 | Poecilia formosa | 77.54 | 4e-103 | 303 |
| LLPS-Tar-3876 | Takifugu rubripes | 67.21 | 2e-87 | 262 |
| LLPS-Ten-3499 | Tetraodon nigroviridis | 64.74 | 4e-77 | 236 |
| LLPS-Abg-1477 | Absidia glauca | 62.5 | 3e-14 | 69.7 |
| LLPS-Drm-1995 | Drosophila melanogaster | 57.32 | 5e-64 | 202 |
| LLPS-Cii-2299 | Ciona intestinalis | 56.32 | 4e-68 | 213 |
| LLPS-Spr-1570 | Sporisorium reilianum | 52.8 | 6e-52 | 172 |
| LLPS-Asni-0269 | Aspergillus niger | 52.21 | 7e-41 | 142 |
| LLPS-Usm-0924 | Ustilago maydis | 51.85 | 1e-49 | 174 |
| LLPS-Amt-1737 | Amborella trichopoda | 50.61 | 2e-50 | 167 |
| LLPS-Vir-1351 | Vigna radiata | 49.56 | 2e-33 | 123 |
| LLPS-Ved-1479 | Verticillium dahliae | 48.5 | 8e-48 | 161 |
| LLPS-Fus-0565 | Fusarium solani | 48.47 | 2e-44 | 152 |
| LLPS-Org-2046 | Oryza glaberrima | 48.18 | 9e-39 | 136 |
| LLPS-Cog-0986 | Colletotrichum gloeosporioides | 47.95 | 9e-49 | 164 |
| LLPS-Trr-0547 | Trichoderma reesei | 47.83 | 1e-47 | 161 |
| LLPS-Orb-0811 | Oryza barthii | 47.79 | 6e-38 | 134 |
| LLPS-Ori-0913 | Oryza indica | 47.69 | 3e-35 | 127 |
| LLPS-Lep-0908 | Leersia perrieri | 47.56 | 5e-47 | 159 |
| LLPS-Met-0886 | Medicago truncatula | 47.56 | 4e-47 | 159 |
| LLPS-Fuo-1015 | Fusarium oxysporum | 47.2 | 3e-45 | 155 |
| LLPS-Fuv-1435 | Fusarium verticillioides | 46.95 | 6e-46 | 156 |
| LLPS-Prp-1329 | Prunus persica | 46.95 | 2e-47 | 160 |
| LLPS-Sem-0857 | Selaginella moellendorffii | 46.82 | 5e-40 | 141 |
| LLPS-Sei-1912 | Setaria italica | 46.78 | 6e-49 | 164 |
| LLPS-Orni-2227 | Oryza nivara | 46.78 | 7e-48 | 161 |
| LLPS-Asn-0121 | Aspergillus nidulans | 46.78 | 9e-46 | 155 |
| LLPS-Orr-1408 | Oryza rufipogon | 46.78 | 7e-48 | 161 |
| LLPS-Zem-1881 | Zea mays | 46.78 | 7e-49 | 164 |
| LLPS-Orp-0301 | Oryza punctata | 46.78 | 6e-48 | 161 |
| LLPS-Ors-2366 | Oryza sativa | 46.78 | 7e-48 | 161 |
| LLPS-Sob-2237 | Sorghum bicolor | 46.78 | 9e-49 | 163 |
| LLPS-Php-0576 | Physcomitrella patens | 46.56 | 2e-48 | 162 |
| LLPS-Orbr-1007 | Oryza brachyantha | 46.47 | 1e-47 | 161 |
| LLPS-Cus-2068 | Cucumis sativus | 46.39 | 3e-44 | 152 |
| LLPS-Miv-0992 | Microbotryum violaceum | 46.39 | 1e-42 | 152 |
| LLPS-Via-0512 | Vigna angularis | 46.34 | 6e-46 | 156 |
| LLPS-Beb-1276 | Beauveria bassiana | 46.34 | 5e-47 | 159 |
| LLPS-Phv-0905 | Phaseolus vulgaris | 46.34 | 1e-45 | 155 |
| LLPS-Mae-0299 | Manihot esculenta | 46.34 | 5e-46 | 156 |
| LLPS-Mua-2169 | Musa acuminata | 46.24 | 3e-49 | 165 |
| LLPS-Trv-0702 | Trichoderma virens | 46.15 | 5e-49 | 165 |
| LLPS-Pyt-1157 | Pyrenophora teres | 46.11 | 1e-49 | 166 |
| LLPS-Pytr-1493 | Pyrenophora triticirepentis | 46.11 | 1e-49 | 166 |
| LLPS-Phn-1075 | Phaeosphaeria nodorum | 46.11 | 3e-46 | 157 |
| LLPS-Gag-0855 | Gaeumannomyces graminis | 46.02 | 3e-48 | 163 |
| LLPS-Map-1409 | Magnaporthe poae | 46.02 | 1e-47 | 161 |
| LLPS-Aso-0699 | Aspergillus oryzae | 45.88 | 1e-42 | 148 |
| LLPS-Thc-2491 | Theobroma cacao | 45.73 | 1e-45 | 155 |
| LLPS-Coc-0266 | Corchorus capsularis | 45.73 | 6e-46 | 156 |
| LLPS-Nef-1475 | Neosartorya fischeri | 45.61 | 2e-45 | 155 |
| LLPS-Coo-1605 | Colletotrichum orbiculare | 45.6 | 3e-49 | 165 |
| LLPS-Orgl-2052 | Oryza glumaepatula | 45.45 | 1e-39 | 139 |
| LLPS-Scc-1473 | Schizosaccharomyces cryophilus | 45.34 | 2e-37 | 133 |
| LLPS-Kop-0010 | Komagataella pastoris | 45.29 | 2e-37 | 134 |
| LLPS-Mel-0111 | Melampsora laricipopulina | 45.18 | 1e-43 | 150 |
| LLPS-Pot-2704 | Populus trichocarpa | 45.14 | 1e-45 | 155 |
| LLPS-Viv-1946 | Vitis vinifera | 45.12 | 3e-45 | 154 |
| LLPS-Gor-2541 | Gossypium raimondii | 45.12 | 9e-45 | 153 |
| LLPS-Hov-0114 | Hordeum vulgare | 45.09 | 6e-46 | 157 |
| LLPS-Cogr-0992 | Colletotrichum graminicola | 45.05 | 1e-48 | 164 |
| LLPS-Hea-0170 | Helianthus annuus | 45.03 | 4e-46 | 157 |
| LLPS-Nia-1893 | Nicotiana attenuata | 44.89 | 3e-46 | 157 |
| LLPS-Brd-0484 | Brachypodium distachyon | 44.77 | 4e-45 | 154 |
| LLPS-Tra-1573 | Triticum aestivum | 44.71 | 8e-46 | 156 |
| LLPS-Sol-1091 | Solanum lycopersicum | 44.7 | 1e-33 | 122 |
| LLPS-Put-1327 | Puccinia triticina | 44.58 | 2e-43 | 150 |
| LLPS-Art-2479 | Arabidopsis thaliana | 44.51 | 9e-45 | 153 |
| LLPS-Pug-0444 | Puccinia graminis | 44.51 | 5e-44 | 151 |
| LLPS-Dos-0857 | Dothistroma septosporum | 44.39 | 1e-44 | 153 |
| LLPS-Nec-0645 | Neurospora crassa | 44.32 | 8e-47 | 160 |
| LLPS-Asg-1536 | Ashbya gossypii | 44.31 | 5e-37 | 133 |
| LLPS-Orm-0296 | Oryza meridionalis | 44.2 | 3e-44 | 152 |
| LLPS-Yal-1149 | Yarrowia lipolytica | 44.17 | 2e-39 | 139 |
| LLPS-Blg-0858 | Blumeria graminis | 44.13 | 5e-44 | 151 |
| LLPS-Ast-0256 | Aspergillus terreus | 44.12 | 3e-42 | 147 |
| LLPS-Mao-1533 | Magnaporthe oryzae | 44.1 | 1e-49 | 166 |
| LLPS-Arl-0722 | Arabidopsis lyrata | 43.9 | 2e-44 | 152 |
| LLPS-Asfu-0489 | Aspergillus fumigatus | 43.71 | 2e-35 | 129 |
| LLPS-Glm-1736 | Glycine max | 43.68 | 1e-45 | 155 |
| LLPS-Asc-1694 | Aspergillus clavatus | 43.68 | 4e-46 | 157 |
| LLPS-Scp-1429 | Schizosaccharomyces pombe | 43.37 | 2e-34 | 126 |
| LLPS-Sot-1061 | Solanum tuberosum | 43.35 | 2e-45 | 155 |
| LLPS-Zyt-1479 | Zymoseptoria tritici | 42.86 | 1e-41 | 145 |
| LLPS-Sac-1216 | Saccharomyces cerevisiae | 42.77 | 2e-34 | 127 |
| LLPS-Brr-0133 | Brassica rapa | 42.68 | 3e-43 | 149 |
| LLPS-Asf-0688 | Aspergillus flavus | 42.67 | 5e-31 | 120 |
| LLPS-Brn-2960 | Brassica napus | 42.35 | 9e-44 | 150 |
| LLPS-Scj-1452 | Schizosaccharomyces japonicus | 42.29 | 3e-34 | 125 |
| LLPS-Tru-1909 | Triticum urartu | 42.22 | 1e-42 | 148 |
| LLPS-Bro-2664 | Brassica oleracea | 42.07 | 2e-42 | 147 |
| LLPS-Chc-0105 | Chondrus crispus | 40.68 | 4e-39 | 139 |
| LLPS-Cae-0436 | Caenorhabditis elegans | 40.34 | 9e-40 | 140 |
| LLPS-Crn-0936 | Cryptococcus neoformans | 39.49 | 1e-39 | 141 |
| LLPS-Gas-0783 | Galdieria sulphuraria | 39.29 | 2e-36 | 132 |
| LLPS-Chr-0693 | Chlamydomonas reinhardtii | 38.92 | 9e-37 | 132 |
| LLPS-Tum-1438 | Tuber melanosporum | 37.74 | 2e-18 | 82.8 |
| LLPS-Osl-1071 | Ostreococcus lucimarinus | 36.94 | 4e-30 | 114 |
| LLPS-Lem-1236 | Leptosphaeria maculans | 36.0 | 9e-18 | 80.9 |
| LLPS-Dac-1820 | Daucus carota | 35.48 | 2e-09 | 57.0 |
| LLPS-Cym-0780 | Cyanidioschyzon merolae | 33.73 | 2e-21 | 92.8 |