• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pap-1643
VBP1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Prefoldin subunit 3
Gene Name: VBP1
Ensembl Gene: ENSPPAG00000036017.1
Ensembl Protein: ENSPPAP00000025780.1
Organism: Pan paniscus
Taxa ID: 9597
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAVKDSCGK  GEMATGNGRR  LHLGIPEAVF  VEDVDSFMKQ  PGNETADTVL  KKLDEQYQKY  60
61    KFMELNLAQK  KRRLKGQIPE  IKQTLEILKY  MQKKKESTNS  METRFLLADN  LYCKASVPPT  120
121   DKVCLWLGAN  VMLEYDIDEA  QALLEKNLST  ATKNLDSLEE  DLDFLRDQFT  TTEVNMARVY  180
181   NWDVKRRNKD  DSTKNKA  197
Nucleotide CDS Sequence (FASTA)
1     ATGGCACCTC  AACCCATGAT  TCATACCCAG  CAAGGCCTAA  GGACCAGTAG  TCCTTCCACT  60
61    CCATCCCCAG  AACATCAGGA  AGATGTAGAT  TCCTTCATGA  AACAGCCTGG  GAATGAGACT  120
121   GCAGATACAG  TATTAAAGAA  GCTGGATGAA  CAGTACCAGA  AGTATAAGTT  TATGGAACTC  180
181   AACCTTGCTC  AAAAGAAAAG  AAGGCTAAAA  GGTCAGATTC  CTGAAATTAA  ACAGACTTTG  240
241   GAAATTCTAA  AATACATGCA  GAAGAAAAAA  GAGTCCACCA  ACTCAATGGA  GACCAGATTC  300
301   TTGCTGGCAG  ATAACCTGTA  TTGCAAAGCT  TCAGTTCCTC  CTACCGATAA  AGTGTGTCTG  360
361   TGGTTGGGGG  CTAATGTAAT  GCTTGAATAT  GATATTGATG  AAGCTCAGGC  ATTGTTGGAA  420
421   AAGAATTTAT  CGACTGCCAC  AAAGAATCTT  GATTCCCTGG  AGGAAGACCT  TGACTTTCTT  480
481   CGAGATCAAT  TTACTACCAC  AGAAGTCAAT  ATGGCCAGGG  TTTATAATTG  GGATGTAAAA  540
541   AGAAGAAACA  AGGATGACTC  TACCAAGAAC  AAAGCATAA  579

▼ KEYWORD

ID
Family
Chaperone
Coiled coil
Complete proteome
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytosol
Cellular Component
Intracellular membrane-bounded organelle
Cellular Component
Prefoldin complex
Biological Process
Protein folding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Poa-3596Pongo abelii100.03e-144 407
LLPS-Nol-2834Nomascus leucogenys100.03e-144 407
LLPS-Pat-3142Pan troglodytes100.03e-144 407
LLPS-Hos-0555Homo sapiens100.03e-144 407
LLPS-Gog-1861Gorilla gorilla100.03e-144 407
LLPS-Mam-4616Macaca mulatta99.498e-144 406
LLPS-Man-3236Macaca nemestrina99.498e-144 406
LLPS-Mal-1787Mandrillus leucophaeus99.498e-144 406
LLPS-Paa-4142Papio anubis99.494e-143 406
LLPS-Cea-2219Cercocebus atys99.493e-143 406
LLPS-Maf-1328Macaca fascicularis99.498e-144 406
LLPS-Urm-1628Ursus maritimus98.756e-112 323
LLPS-Caj-3724Callithrix jacchus97.974e-141 399
LLPS-Chs-1240Chlorocebus sabaeus97.492e-140 399
LLPS-Eqc-0808Equus caballus97.461e-140 398
LLPS-Mum-4073Mus musculus96.953e-137 389
LLPS-Caf-3695Canis familiaris96.456e-139 393
LLPS-Otg-0664Otolemur garnettii96.393e-115 333
LLPS-Loa-3569Loxodonta africana95.962e-137 390
LLPS-Cap-2047Cavia porcellus95.949e-138 390
LLPS-Fec-2707Felis catus95.941e-138 392
LLPS-Tut-1608Tursiops truncatus95.944e-137 389
LLPS-Mup-2383Mustela putorius furo95.942e-138 392
LLPS-Sus-1203Sus scrofa95.941e-137 392
LLPS-Ict-3866Ictidomys tridecemlineatus95.432e-135 384
LLPS-Cas-1705Carlito syrichta95.435e-137 389
LLPS-Bot-3970Bos taurus95.435e-137 389
LLPS-Ova-1562Ovis aries95.435e-137 389
LLPS-Gaga-3288Gallus gallus95.03e-108 314
LLPS-Mea-1808Mesocricetus auratus94.922e-136 387
LLPS-Meg-1915Meleagris gallopavo94.641e-113 328
LLPS-Pes-3587Pelodiscus sinensis94.584e-112 324
LLPS-Aon-4066Aotus nancymaae94.254e-116 335
LLPS-Aim-2086Ailuropoda melanoleuca93.941e-132 377
LLPS-Orc-3626Oryctolagus cuniculus93.914e-133 380
LLPS-Ora-3123Ornithorhynchus anatinus93.14e-95 280
LLPS-Fud-0979Fukomys damarensis92.893e-133 379
LLPS-Myl-2125Myotis lucifugus92.462e-132 377
LLPS-Fia-2828Ficedula albicollis92.186e-117 339
LLPS-Tag-2291Taeniopygia guttata91.627e-117 337
LLPS-Anc-3584Anolis carolinensis90.535e-124 355
LLPS-Lac-1705Latimeria chalumnae87.361e-113 330
LLPS-Anp-0765Anas platyrhynchos86.321e-112 327
LLPS-Dio-3278Dipodomys ordii84.267e-115 332
LLPS-Xet-2986Xenopus tropicalis83.253e-117 338
LLPS-Rhb-1684Rhinopithecus bieti82.933e-87 261
LLPS-Leo-1983Lepisosteus oculatus81.038e-114 330
LLPS-Sah-0547Sarcophilus harrisii80.932e-114 332
LLPS-Dar-3929Danio rerio80.546e-109 317
LLPS-Icp-2754Ictalurus punctatus79.674e-107 312
LLPS-Orn-0484Oreochromis niloticus79.494e-112 325
LLPS-Ran-1786Rattus norvegicus77.352e-100 295
LLPS-Gaa-2723Gasterosteus aculeatus77.322e-107 313
LLPS-Orl-4003Oryzias latipes76.418e-107 312
LLPS-Scf-2814Scleropages formosus76.291e-107 313
LLPS-Asm-4015Astyanax mexicanus76.143e-95 283
LLPS-Pof-2098Poecilia formosa75.03e-104 305
LLPS-Tar-3876Takifugu rubripes65.648e-89 266
LLPS-Abg-1477Absidia glauca62.53e-1469.3
LLPS-Ten-3499Tetraodon nigroviridis60.516e-78 238
LLPS-Cii-2299Ciona intestinalis56.92e-68 214
LLPS-Spr-1570Sporisorium reilianum52.86e-52 172
LLPS-Drm-1995Drosophila melanogaster51.876e-64 202
LLPS-Usm-0924Ustilago maydis51.851e-49 174
LLPS-Asni-0269Aspergillus niger50.745e-40 140
LLPS-Amt-1737Amborella trichopoda50.03e-50 167
LLPS-Vir-1351Vigna radiata48.673e-33 123
LLPS-Ved-1479Verticillium dahliae48.58e-48 161
LLPS-Org-2046Oryza glaberrima47.451e-38 136
LLPS-Sem-0857Selaginella moellendorffii47.49e-41 143
LLPS-Orb-0811Oryza barthii47.061e-37 134
LLPS-Lep-0908Leersia perrieri46.957e-47 159
LLPS-Met-0886Medicago truncatula46.955e-47 159
LLPS-Ori-0913Oryza indica46.924e-35 126
LLPS-Coo-1605Colletotrichum orbiculare46.673e-49 165
LLPS-Nec-0645Neurospora crassa46.582e-46 160
LLPS-Php-0576Physcomitrella patens46.565e-49 164
LLPS-Gag-0855Gaeumannomyces graminis46.551e-47 161
LLPS-Miv-0992Microbotryum violaceum46.391e-42 152
LLPS-Prp-1329Prunus persica46.343e-47 160
LLPS-Cog-0986Colletotrichum gloeosporioides46.241e-48 164
LLPS-Orr-1408Oryza rufipogon46.29e-48 161
LLPS-Orp-0301Oryza punctata46.29e-48 161
LLPS-Ors-2366Oryza sativa46.29e-48 161
LLPS-Sob-2237Sorghum bicolor46.21e-48 163
LLPS-Orni-2227Oryza nivara46.29e-48 161
LLPS-Cogr-0992Colletotrichum graminicola45.951e-48 164
LLPS-Orbr-1007Oryza brachyantha45.881e-47 160
LLPS-Cus-2068Cucumis sativus45.786e-44 151
LLPS-Pyt-1157Pyrenophora teres45.765e-49 164
LLPS-Mae-0299Manihot esculenta45.735e-46 156
LLPS-Phv-0905Phaseolus vulgaris45.732e-45 155
LLPS-Via-0512Vigna angularis45.737e-46 156
LLPS-Scc-1473Schizosaccharomyces cryophilus45.664e-38 135
LLPS-Mua-2169Musa acuminata45.664e-49 164
LLPS-Hea-0170Helianthus annuus45.611e-45 155
LLPS-Asn-0121Aspergillus nidulans45.616e-45 154
LLPS-Map-1409Magnaporthe poae45.568e-48 162
LLPS-Phn-1075Phaeosphaeria nodorum45.515e-46 157
LLPS-Nia-1893Nicotiana attenuata45.511e-45 155
LLPS-Beb-1276Beauveria bassiana45.32e-47 160
LLPS-Aso-0699Aspergillus oryzae45.293e-42 147
LLPS-Pytr-1493Pyrenophora triticirepentis45.262e-49 165
LLPS-Fus-0565Fusarium solani45.162e-44 152
LLPS-Thc-2491Theobroma cacao45.122e-45 155
LLPS-Trv-0702Trichoderma virens45.056e-48 162
LLPS-Orgl-2052Oryza glumaepatula44.812e-39 139
LLPS-Zem-1881Zea mays44.759e-49 163
LLPS-Sei-1912Setaria italica44.756e-49 164
LLPS-Kop-0010Komagataella pastoris44.713e-37 134
LLPS-Dos-0857Dothistroma septosporum44.677e-46 156
LLPS-Viv-1946Vitis vinifera44.515e-45 154
LLPS-Gor-2541Gossypium raimondii44.511e-44 153
LLPS-Hov-0114Hordeum vulgare44.519e-46 156
LLPS-Nef-1475Neosartorya fischeri44.441e-44 153
LLPS-Zyt-1479Zymoseptoria tritici44.312e-41 144
LLPS-Brd-0484Brachypodium distachyon44.195e-45 154
LLPS-Yal-1149Yarrowia lipolytica44.172e-39 139
LLPS-Ast-0256Aspergillus terreus44.125e-42 146
LLPS-Tra-1573Triticum aestivum44.121e-45 156
LLPS-Fuo-1015Fusarium oxysporum44.023e-45 155
LLPS-Trr-0547Trichoderma reesei44.024e-48 162
LLPS-Put-1327Puccinia triticina43.984e-43 149
LLPS-Sol-1091Solanum lycopersicum43.942e-33 122
LLPS-Art-2479Arabidopsis thaliana43.92e-44 152
LLPS-Pug-0444Puccinia graminis43.98e-44 151
LLPS-Coc-0266Corchorus capsularis43.855e-46 157
LLPS-Fuv-1435Fusarium verticillioides43.855e-46 157
LLPS-Mao-1533Magnaporthe oryzae43.817e-50 167
LLPS-Mel-0111Melampsora laricipopulina43.752e-43 150
LLPS-Asg-1536Ashbya gossypii43.711e-36 132
LLPS-Orm-0296Oryza meridionalis43.654e-44 152
LLPS-Asc-1694Aspergillus clavatus43.651e-44 153
LLPS-Arl-0722Arabidopsis lyrata43.293e-44 152
LLPS-Blg-0858Blumeria graminis43.241e-43 150
LLPS-Pot-2704Populus trichocarpa43.237e-46 156
LLPS-Glm-1736Glycine max43.11e-45 155
LLPS-Sot-1061Solanum tuberosum42.773e-45 155
LLPS-Sac-1216Saccharomyces cerevisiae42.772e-34 126
LLPS-Asfu-0489Aspergillus fumigatus42.381e-34 127
LLPS-Scp-1429Schizosaccharomyces pombe42.372e-35 128
LLPS-Brr-0133Brassica rapa42.073e-43 149
LLPS-Brn-2960Brassica napus41.769e-44 151
LLPS-Asf-0688Aspergillus flavus41.721e-30 119
LLPS-Scj-1452Schizosaccharomyces japonicus41.717e-34 124
LLPS-Tru-1909Triticum urartu41.672e-42 148
LLPS-Bro-2664Brassica oleracea41.463e-42 147
LLPS-Chc-0105Chondrus crispus40.79e-39 138
LLPS-Cae-0436Caenorhabditis elegans40.349e-40 140
LLPS-Crn-0936Cryptococcus neoformans40.03e-40 143
LLPS-Gas-0783Galdieria sulphuraria39.883e-37 133
LLPS-Chr-0693Chlamydomonas reinhardtii38.926e-37 133
LLPS-Tum-1438Tuber melanosporum37.742e-1882.4
LLPS-Osl-1071Ostreococcus lucimarinus36.944e-30 114
LLPS-Dac-1820Daucus carota35.482e-0956.6
LLPS-Lem-1236Leptosphaeria maculans34.623e-1882.4
LLPS-Cym-0780Cyanidioschyzon merolae33.133e-2192.4