DrLLPS - Data resource of LLPS

LLPS-Icp-2754
vbp1

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Prefoldin subunit 3
Gene Name:	vbp1
Ensembl Gene:	ENSIPUG00000020555.1
Ensembl Protein:	ENSIPUP00000030421.1
Organism:	Ictalurus punctatus
Taxa ID:	7998
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0555	P61758	Client	Stress granule	79.67	4e-107	312

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSIPUT00000031646.1	ENSIPUP00000030421.1
Ensembl	ENSIPUT00000031661.1	ENSIPUP00000030435.1
UniProt		A0A2D0RCN4, A0A2D0RCN4_ICTPU
RefSeq	, XM_017472815.1	, XP_017328304.1, XP_017328304.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAATIENNSA AAANKKKHLG IPEAVFVEDV DSFMKKPGND TADVVLRKLD EQYQKYKYME 60 61 VNLVQKKMRL KNQIPQIKQT LEILRHMQEK RDTTDPMETH FLLADNVYCK ASVPPTDKVC 120 121 LWLGANVMLE YDIDEAQTLL EKNLGTASRN LESLEEDLDF LRDQFTTTEV NMARVYNWDV 180 181 KRRSKDNLLK SAERS 195
Nucleotide CDS Sequence (FASTA)
1 ATGGCGGCCA CCATAGAGAA CAATAGCGCT GCAGCTGCGA ATAAGAAAAA ACATTTAGGA 60 61 ATTCCTGAAG CAGTGTTTGT AGAGGATGTG GATTCGTTTA TGAAGAAGCC CGGCAACGAC 120 121 ACGGCGGACG TCGTACTGAG GAAGCTTGAT GAACAGTACC AGAAATATAA ATACATGGAA 180 181 GTCAACCTGG TTCAGAAAAA AATGAGGTTG AAAAACCAGA TTCCACAAAT CAAGCAGACG 240 241 TTAGAAATCT TACGGCACAT GCAGGAGAAA AGGGACACTA CAGATCCAAT GGAGACGCAC 300 301 TTCCTATTGG CTGATAATGT GTACTGCAAG GCCTCTGTCC CGCCCACGGA TAAAGTGTGT 360 361 TTGTGGCTTG GGGCCAATGT AATGTTGGAG TATGACATAG ATGAAGCTCA GACACTGCTG 420 421 GAGAAGAATC TCGGCACGGC CTCTCGAAAC CTGGAGTCTC TGGAGGAGGA CCTGGACTTC 480 481 CTCCGAGACC AATTCACAAC CACTGAAGTC AATATGGCAC GTGTGTACAA CTGGGATGTC 540 541 AAGAGGAGGA GCAAAGACAA CCTTCTTAAA TCAGCTGAGA GGTCTTAG 588

▼ KEYWORD

ID	Family
KW-0143	Chaperone
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0016272	Cellular Component	Prefoldin complex
GO:0006457	Biological Process	Protein folding

▼ KEGG

ipu:108268106

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Dar-3929	Danio rerio	92.13	1e-121	349
LLPS-Asm-4015	Astyanax mexicanus	90.97	6e-103	302
LLPS-Scf-2814	Scleropages formosus	89.33	3e-118	341
LLPS-Orn-0484	Oreochromis niloticus	88.76	5e-118	340
LLPS-Orl-4003	Oryzias latipes	88.2	2e-116	336
LLPS-Pof-2098	Poecilia formosa	86.19	5e-112	325
LLPS-Gaa-2723	Gasterosteus aculeatus	85.96	4e-114	330
LLPS-Leo-1983	Lepisosteus oculatus	85.96	2e-114	331
LLPS-Anc-3584	Anolis carolinensis	85.63	2e-110	321
LLPS-Pes-3587	Pelodiscus sinensis	85.62	2e-100	294
LLPS-Xet-2986	Xenopus tropicalis	85.06	5e-109	317
LLPS-Tag-2291	Taeniopygia guttata	85.03	4e-104	305
LLPS-Fia-2828	Ficedula albicollis	85.03	1e-103	305
LLPS-Anp-0765	Anas platyrhynchos	84.38	9e-99	291
LLPS-Lac-1705	Latimeria chalumnae	84.0	8e-108	315
LLPS-Meg-1915	Meleagris gallopavo	83.95	1e-99	293
LLPS-Gaga-3288	Gallus gallus	83.77	2e-94	279
LLPS-Mam-4616	Macaca mulatta	82.76	4e-106	310
LLPS-Poa-3596	Pongo abelii	82.76	6e-106	310
LLPS-Nol-2834	Nomascus leucogenys	82.76	6e-106	310
LLPS-Man-3236	Macaca nemestrina	82.76	4e-106	310
LLPS-Hos-0555	Homo sapiens	82.76	6e-106	310
LLPS-Pap-1643	Pan paniscus	82.76	6e-106	310
LLPS-Pat-3142	Pan troglodytes	82.76	6e-106	310
LLPS-Mal-1787	Mandrillus leucophaeus	82.76	4e-106	310
LLPS-Paa-4142	Papio anubis	82.76	3e-105	309
LLPS-Cea-2219	Cercocebus atys	82.76	2e-105	310
LLPS-Mum-4073	Mus musculus	82.76	7e-106	309
LLPS-Maf-1328	Macaca fascicularis	82.76	4e-106	310
LLPS-Mea-1808	Mesocricetus auratus	82.76	5e-106	310
LLPS-Ora-3123	Ornithorhynchus anatinus	82.76	2e-86	258
LLPS-Caj-3724	Callithrix jacchus	82.76	3e-106	310
LLPS-Gog-1861	Gorilla gorilla	82.76	6e-106	310
LLPS-Fud-0979	Fukomys damarensis	82.66	8e-105	307
LLPS-Caf-3695	Canis familiaris	82.18	5e-105	307
LLPS-Cap-2047	Cavia porcellus	82.18	2e-105	308
LLPS-Eqc-0808	Equus caballus	82.18	2e-105	308
LLPS-Ict-3866	Ictidomys tridecemlineatus	82.18	3e-105	308
LLPS-Cas-1705	Carlito syrichta	82.18	1e-104	306
LLPS-Fec-2707	Felis catus	82.18	6e-106	310
LLPS-Orc-3626	Oryctolagus cuniculus	82.18	5e-104	306
LLPS-Bot-3970	Bos taurus	82.18	5e-105	307
LLPS-Tut-1608	Tursiops truncatus	82.18	2e-105	308
LLPS-Ova-1562	Ovis aries	82.18	5e-105	307
LLPS-Mup-2383	Mustela putorius furo	82.18	3e-105	308
LLPS-Sus-1203	Sus scrofa	82.18	1e-104	308
LLPS-Otg-0664	Otolemur garnettii	81.94	1e-92	275
LLPS-Loa-3569	Loxodonta africana	81.71	1e-103	304
LLPS-Chs-1240	Chlorocebus sabaeus	80.68	1e-102	303
LLPS-Myl-2125	Myotis lucifugus	80.57	1e-101	299
LLPS-Urm-1628	Ursus maritimus	80.38	5e-92	273
LLPS-Aim-2086	Ailuropoda melanoleuca	79.43	5e-98	290
LLPS-Sah-0547	Sarcophilus harrisii	78.7	2e-98	290
LLPS-Aon-4066	Aotus nancymaae	77.33	1e-95	283
LLPS-Dio-3278	Dipodomys ordii	76.44	5e-93	276
LLPS-Ran-1786	Rattus norvegicus	73.75	1e-86	260
LLPS-Rhb-1684	Rhinopithecus bieti	72.67	1e-71	221
LLPS-Tar-3876	Takifugu rubripes	72.09	3e-92	275
LLPS-Ten-3499	Tetraodon nigroviridis	67.8	3e-85	257
LLPS-Abg-1477	Absidia glauca	62.5	2e-14	70.1
LLPS-Cii-2299	Ciona intestinalis	57.83	8e-66	207
LLPS-Drm-1995	Drosophila melanogaster	55.09	3e-58	188
LLPS-Amt-1737	Amborella trichopoda	50.3	4e-49	164
LLPS-Vir-1351	Vigna radiata	49.56	3e-33	123
LLPS-Asni-0269	Aspergillus niger	49.26	6e-39	137
LLPS-Ori-0913	Oryza indica	49.19	1e-33	122
LLPS-Sem-0857	Selaginella moellendorffii	49.1	8e-41	143
LLPS-Org-2046	Oryza glaberrima	48.87	7e-37	131
LLPS-Nec-0645	Neurospora crassa	48.47	3e-47	162
LLPS-Map-1409	Magnaporthe poae	48.47	7e-46	157
LLPS-Aso-0699	Aspergillus oryzae	48.26	3e-44	152
LLPS-Ved-1479	Verticillium dahliae	47.93	2e-46	158
LLPS-Zem-1881	Zea mays	47.9	1e-46	158
LLPS-Orbr-1007	Oryza brachyantha	47.9	4e-46	157
LLPS-Coo-1605	Colletotrichum orbiculare	47.9	1e-48	164
LLPS-Beb-1276	Beauveria bassiana	47.83	1e-47	160
LLPS-Trr-0547	Trichoderma reesei	47.83	2e-47	160
LLPS-Ast-0256	Aspergillus terreus	47.67	1e-44	153
LLPS-Usm-0924	Ustilago maydis	47.53	8e-46	163
LLPS-Orb-0811	Oryza barthii	47.41	6e-36	129
LLPS-Pytr-1493	Pyrenophora triticirepentis	47.34	2e-48	163
LLPS-Pyt-1157	Pyrenophora teres	47.34	3e-48	162
LLPS-Cog-0986	Colletotrichum gloeosporioides	47.31	8e-48	161
LLPS-Sei-1912	Setaria italica	47.31	2e-46	157
LLPS-Spr-1570	Sporisorium reilianum	47.2	3e-46	157
LLPS-Trv-0702	Trichoderma virens	47.2	8e-47	159
LLPS-Sob-2237	Sorghum bicolor	47.06	4e-47	159
LLPS-Cogr-0992	Colletotrichum graminicola	46.71	1e-47	161
LLPS-Lep-0908	Leersia perrieri	46.71	5e-45	154
LLPS-Fus-0565	Fusarium solani	46.63	2e-42	147
LLPS-Fuo-1015	Fusarium oxysporum	46.58	1e-43	150
LLPS-Orr-1408	Oryza rufipogon	46.47	1e-45	155
LLPS-Orp-0301	Oryza punctata	46.47	1e-45	155
LLPS-Ors-2366	Oryza sativa	46.47	1e-45	155
LLPS-Orni-2227	Oryza nivara	46.47	1e-45	155
LLPS-Cus-2068	Cucumis sativus	46.39	1e-43	150
LLPS-Prp-1329	Prunus persica	46.34	4e-45	154
LLPS-Mae-0299	Manihot esculenta	46.34	2e-45	155
LLPS-Phv-0905	Phaseolus vulgaris	46.34	5e-45	154
LLPS-Met-0886	Medicago truncatula	46.34	2e-45	155
LLPS-Fuv-1435	Fusarium verticillioides	46.34	2e-44	152
LLPS-Mua-2169	Musa acuminata	46.34	2e-46	157
LLPS-Phn-1075	Phaeosphaeria nodorum	46.15	4e-46	157
LLPS-Mao-1533	Magnaporthe oryzae	46.11	1e-46	159
LLPS-Gag-0855	Gaeumannomyces graminis	45.96	8e-45	154
LLPS-Coc-0266	Corchorus capsularis	45.73	3e-45	154
LLPS-Via-0512	Vigna angularis	45.73	9e-45	153
LLPS-Zyt-1479	Zymoseptoria tritici	45.56	4e-42	146
LLPS-Dos-0857	Dothistroma septosporum	45.51	8e-43	148
LLPS-Asf-0688	Aspergillus flavus	45.39	8e-33	125
LLPS-Viv-1946	Vitis vinifera	45.12	6e-45	154
LLPS-Miv-0992	Microbotryum violaceum	45.12	3e-40	145
LLPS-Glm-1736	Glycine max	45.12	1e-44	153
LLPS-Hea-0170	Helianthus annuus	45.12	3e-44	152
LLPS-Mel-0111	Melampsora laricipopulina	45.12	5e-45	154
LLPS-Asn-0121	Aspergillus nidulans	45.09	1e-42	148
LLPS-Yal-1149	Yarrowia lipolytica	44.79	6e-39	138
LLPS-Sol-1091	Solanum lycopersicum	44.63	2e-31	117
LLPS-Php-0576	Physcomitrella patens	44.57	6e-45	154
LLPS-Gor-2541	Gossypium raimondii	44.51	2e-43	150
LLPS-Nia-1893	Nicotiana attenuata	44.51	2e-44	152
LLPS-Pot-2704	Populus trichocarpa	44.44	2e-44	152
LLPS-Blg-0858	Blumeria graminis	44.38	2e-40	142
LLPS-Brd-0484	Brachypodium distachyon	44.19	6e-44	151
LLPS-Asc-1694	Aspergillus clavatus	44.19	1e-41	145
LLPS-Orm-0296	Oryza meridionalis	43.89	5e-42	147
LLPS-Thc-2491	Theobroma cacao	43.75	3e-45	154
LLPS-Asg-1536	Ashbya gossypii	43.71	4e-38	136
LLPS-Tra-1573	Triticum aestivum	43.6	6e-44	151
LLPS-Orgl-2052	Oryza glumaepatula	43.51	2e-37	134
LLPS-Hov-0114	Hordeum vulgare	43.35	3e-43	149
LLPS-Art-2479	Arabidopsis thaliana	43.29	1e-42	148
LLPS-Nef-1475	Neosartorya fischeri	42.77	1e-40	143
LLPS-Kop-0010	Komagataella pastoris	42.77	3e-36	131
LLPS-Sac-1216	Saccharomyces cerevisiae	42.77	3e-36	131
LLPS-Cae-0436	Caenorhabditis elegans	42.77	2e-42	147
LLPS-Pug-0444	Puccinia graminis	42.68	2e-44	152
LLPS-Sot-1061	Solanum tuberosum	42.68	1e-42	148
LLPS-Arl-0722	Arabidopsis lyrata	42.68	2e-42	147
LLPS-Scc-1473	Schizosaccharomyces cryophilus	42.24	4e-34	125
LLPS-Osl-1071	Ostreococcus lucimarinus	42.18	1e-32	120
LLPS-Put-1327	Puccinia triticina	41.48	2e-43	150
LLPS-Brr-0133	Brassica rapa	41.46	1e-41	145
LLPS-Scp-1429	Schizosaccharomyces pombe	41.42	1e-33	124
LLPS-Tru-1909	Triticum urartu	41.21	1e-40	143
LLPS-Chc-0105	Chondrus crispus	41.21	4e-42	147
LLPS-Asfu-0489	Aspergillus fumigatus	41.18	9e-32	119
LLPS-Scj-1452	Schizosaccharomyces japonicus	41.07	6e-33	122
LLPS-Gas-0783	Galdieria sulphuraria	41.07	2e-38	136
LLPS-Bro-2664	Brassica oleracea	40.85	2e-40	142
LLPS-Chr-0693	Chlamydomonas reinhardtii	40.72	1e-39	140
LLPS-Brn-2960	Brassica napus	39.88	2e-41	144
LLPS-Crn-0936	Cryptococcus neoformans	37.95	1e-36	134
LLPS-Lem-1236	Leptosphaeria maculans	35.4	7e-15	72.8
LLPS-Tum-1438	Tuber melanosporum	34.91	3e-17	79.3
LLPS-Dac-1820	Daucus carota	34.21	3e-07	50.8
LLPS-Cym-0780	Cyanidioschyzon merolae	32.91	1e-17	82.0

LLPS-Icp-2754vbp1

Protein Sequence

Nucleotide Sequence

LLPS-Icp-2754
vbp1