LLPS-Ova-1562
VBP1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Prefoldin subunit 3 |
| Gene Name: | VBP1 |
| Ensembl Gene: | ENSOARG00000003674.1 |
| Ensembl Protein: | ENSOARP00000003916.1 |
| Organism: | Ovis aries |
| Taxa ID: | 9940 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSOART00000003985.1 | ENSOARP00000003916.1 |
| UniProt | W5P0G8, W5P0G8_SHEEP | |
| GeneBank | AMGL01116741 | |
| RefSeq | XM_004022244.2 | XP_004022293.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAASKDGCGV GEVAAGNGRR LHLGIPEAVF VEDVDSFMKQ PGNETADIVL KKLDEQYQKY 60 61 KFMELNLAQK KRRLKGQIPE IKQTLEILKY MQKKKESTSS LETRFLLADN LYCKASVPPT 120 121 DKVCLWLGAN VMLEYDIDEA QALLEKNLLT ATKNLDSLEE DLDFLRDQFT TTEVNMARVY 180 181 NWDVKRRNKD DSTKNKA 197 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCCT CTAAGGACGG TTGTGGTGTA GGAGAAGTGG CTGCGGGGAA CGGGAGGCGA 60 61 CTCCACCTGG GGATTCCTGA AGCGGTTTTT GTGGAAGATG TAGATTCCTT CATGAAACAG 120 121 CCTGGGAATG AGACTGCAGA TATTGTACTG AAGAAGCTGG ATGAACAGTA CCAGAAGTAT 180 181 AAGTTTATGG AACTCAATCT TGCCCAAAAA AAAAGGAGGC TAAAGGGCCA GATTCCTGAA 240 241 ATTAAGCAGA CTTTAGAAAT TCTAAAATAC ATGCAGAAGA AAAAAGAGTC CACCAGTTCA 300 301 CTGGAGACCA GGTTCTTATT GGCAGATAAC CTGTATTGCA AAGCTTCAGT TCCTCCTACC 360 361 GATAAAGTGT GTCTGTGGTT GGGGGCAAAC GTAATGCTTG AATATGATAT TGATGAAGCT 420 421 CAGGCGTTGT TGGAAAAGAA TTTATTGACG GCCACAAAGA ATCTTGATTC TCTTGAGGAA 480 481 GACCTCGACT TTCTTCGAGA TCAGTTTACT ACCACGGAAG TCAATATGGC CAGAGTTTAT 540 541 AATTGGGATG TTAAGAGAAG AAACAAAGAT GATTCTACCA AGAACAAAGC A 591 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Intracellular membrane-bounded organelle | |
Cellular Component | Prefoldin complex | |
Biological Process | Protein folding |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Bot-3970 | Bos taurus | 100.0 | 8e-144 | 406 |
| LLPS-Urm-1628 | Ursus maritimus | 98.75 | 4e-111 | 322 |
| LLPS-Ict-3866 | Ictidomys tridecemlineatus | 97.97 | 1e-138 | 392 |
| LLPS-Fec-2707 | Felis catus | 97.46 | 3e-140 | 397 |
| LLPS-Sus-1203 | Sus scrofa | 97.46 | 2e-139 | 396 |
| LLPS-Mup-2383 | Mustela putorius furo | 97.46 | 2e-140 | 397 |
| LLPS-Eqc-0808 | Equus caballus | 96.95 | 1e-139 | 395 |
| LLPS-Orc-3626 | Oryctolagus cuniculus | 96.94 | 6e-137 | 390 |
| LLPS-Cas-1705 | Carlito syrichta | 96.45 | 8e-139 | 393 |
| LLPS-Caf-3695 | Canis familiaris | 96.45 | 6e-139 | 394 |
| LLPS-Loa-3569 | Loxodonta africana | 95.96 | 6e-138 | 391 |
| LLPS-Mum-4073 | Mus musculus | 95.94 | 1e-136 | 387 |
| LLPS-Tut-1608 | Tursiops truncatus | 95.94 | 3e-137 | 389 |
| LLPS-Pap-1643 | Pan paniscus | 95.43 | 5e-137 | 389 |
| LLPS-Pat-3142 | Pan troglodytes | 95.43 | 5e-137 | 389 |
| LLPS-Hos-0555 | Homo sapiens | 95.43 | 5e-137 | 389 |
| LLPS-Man-3236 | Macaca nemestrina | 95.43 | 2e-137 | 390 |
| LLPS-Nol-2834 | Nomascus leucogenys | 95.43 | 5e-137 | 389 |
| LLPS-Cap-2047 | Cavia porcellus | 95.43 | 7e-138 | 391 |
| LLPS-Poa-3596 | Pongo abelii | 95.43 | 5e-137 | 389 |
| LLPS-Mam-4616 | Macaca mulatta | 95.43 | 2e-137 | 390 |
| LLPS-Gog-1861 | Gorilla gorilla | 95.43 | 5e-137 | 389 |
| LLPS-Maf-1328 | Macaca fascicularis | 95.43 | 2e-137 | 390 |
| LLPS-Cea-2219 | Cercocebus atys | 95.43 | 5e-137 | 390 |
| LLPS-Paa-4142 | Papio anubis | 95.43 | 6e-137 | 390 |
| LLPS-Mal-1787 | Mandrillus leucophaeus | 95.43 | 2e-137 | 390 |
| LLPS-Caj-3724 | Callithrix jacchus | 94.92 | 1e-136 | 387 |
| LLPS-Otg-0664 | Otolemur garnettii | 94.61 | 1e-112 | 326 |
| LLPS-Aim-2086 | Ailuropoda melanoleuca | 94.44 | 4e-133 | 379 |
| LLPS-Mea-1808 | Mesocricetus auratus | 93.91 | 8e-136 | 385 |
| LLPS-Chs-1240 | Chlorocebus sabaeus | 93.47 | 2e-134 | 384 |
| LLPS-Gaga-3288 | Gallus gallus | 93.12 | 3e-106 | 309 |
| LLPS-Ora-3123 | Ornithorhynchus anatinus | 93.1 | 2e-94 | 278 |
| LLPS-Aon-4066 | Aotus nancymaae | 93.1 | 8e-114 | 329 |
| LLPS-Fud-0979 | Fukomys damarensis | 92.89 | 5e-133 | 378 |
| LLPS-Meg-1915 | Meleagris gallopavo | 92.86 | 1e-111 | 323 |
| LLPS-Pes-3587 | Pelodiscus sinensis | 92.77 | 3e-110 | 319 |
| LLPS-Fia-2828 | Ficedula albicollis | 91.06 | 1e-115 | 336 |
| LLPS-Myl-2125 | Myotis lucifugus | 90.95 | 2e-130 | 372 |
| LLPS-Tag-2291 | Taeniopygia guttata | 90.5 | 2e-115 | 334 |
| LLPS-Anc-3584 | Anolis carolinensis | 87.44 | 1e-123 | 355 |
| LLPS-Dio-3278 | Dipodomys ordii | 85.28 | 1e-115 | 335 |
| LLPS-Xet-2986 | Xenopus tropicalis | 83.25 | 8e-118 | 340 |
| LLPS-Anp-0765 | Anas platyrhynchos | 83.16 | 9e-111 | 322 |
| LLPS-Sah-0547 | Sarcophilus harrisii | 82.47 | 1e-115 | 334 |
| LLPS-Lac-1705 | Latimeria chalumnae | 81.82 | 6e-114 | 330 |
| LLPS-Leo-1983 | Lepisosteus oculatus | 81.03 | 7e-113 | 327 |
| LLPS-Dar-3929 | Danio rerio | 80.54 | 2e-108 | 316 |
| LLPS-Rhb-1684 | Rhinopithecus bieti | 80.49 | 4e-84 | 253 |
| LLPS-Orn-0484 | Oreochromis niloticus | 80.0 | 2e-109 | 318 |
| LLPS-Asm-4015 | Astyanax mexicanus | 79.75 | 7e-94 | 279 |
| LLPS-Icp-2754 | Ictalurus punctatus | 79.67 | 8e-107 | 312 |
| LLPS-Ran-1786 | Rattus norvegicus | 77.35 | 5e-100 | 294 |
| LLPS-Scf-2814 | Scleropages formosus | 76.29 | 5e-107 | 312 |
| LLPS-Gaa-2723 | Gasterosteus aculeatus | 76.29 | 3e-106 | 310 |
| LLPS-Orl-4003 | Oryzias latipes | 74.87 | 1e-104 | 306 |
| LLPS-Pof-2098 | Poecilia formosa | 74.0 | 2e-102 | 301 |
| LLPS-Tar-3876 | Takifugu rubripes | 67.21 | 7e-87 | 261 |
| LLPS-Abg-1477 | Absidia glauca | 62.5 | 6e-14 | 68.6 |
| LLPS-Ten-3499 | Tetraodon nigroviridis | 59.49 | 2e-77 | 237 |
| LLPS-Drm-1995 | Drosophila melanogaster | 57.32 | 4e-63 | 200 |
| LLPS-Cii-2299 | Ciona intestinalis | 56.32 | 2e-67 | 211 |
| LLPS-Usm-0924 | Ustilago maydis | 51.85 | 6e-49 | 172 |
| LLPS-Asni-0269 | Aspergillus niger | 51.47 | 1e-39 | 139 |
| LLPS-Amt-1737 | Amborella trichopoda | 50.61 | 4e-49 | 164 |
| LLPS-Vir-1351 | Vigna radiata | 49.56 | 1e-32 | 121 |
| LLPS-Spr-1570 | Sporisorium reilianum | 48.37 | 6e-52 | 172 |
| LLPS-Org-2046 | Oryza glaberrima | 48.18 | 4e-38 | 135 |
| LLPS-Ved-1479 | Verticillium dahliae | 47.9 | 2e-46 | 158 |
| LLPS-Fus-0565 | Fusarium solani | 47.85 | 6e-43 | 149 |
| LLPS-Trr-0547 | Trichoderma reesei | 47.83 | 5e-47 | 159 |
| LLPS-Orb-0811 | Oryza barthii | 47.79 | 3e-37 | 133 |
| LLPS-Ori-0913 | Oryza indica | 47.69 | 1e-34 | 125 |
| LLPS-Cog-0986 | Colletotrichum gloeosporioides | 47.65 | 2e-47 | 160 |
| LLPS-Met-0886 | Medicago truncatula | 47.56 | 1e-45 | 155 |
| LLPS-Lep-0908 | Leersia perrieri | 47.56 | 9e-46 | 156 |
| LLPS-Coo-1605 | Colletotrichum orbiculare | 47.31 | 1e-47 | 161 |
| LLPS-Nec-0645 | Neurospora crassa | 47.24 | 1e-45 | 157 |
| LLPS-Prp-1329 | Prunus persica | 46.95 | 5e-46 | 156 |
| LLPS-Sem-0857 | Selaginella moellendorffii | 46.82 | 3e-39 | 139 |
| LLPS-Sob-2237 | Sorghum bicolor | 46.78 | 2e-47 | 160 |
| LLPS-Ors-2366 | Oryza sativa | 46.78 | 1e-46 | 158 |
| LLPS-Orp-0301 | Oryza punctata | 46.78 | 1e-46 | 158 |
| LLPS-Orr-1408 | Oryza rufipogon | 46.78 | 1e-46 | 158 |
| LLPS-Asn-0121 | Aspergillus nidulans | 46.78 | 4e-45 | 154 |
| LLPS-Orni-2227 | Oryza nivara | 46.78 | 1e-46 | 158 |
| LLPS-Sei-1912 | Setaria italica | 46.78 | 2e-47 | 160 |
| LLPS-Cogr-0992 | Colletotrichum graminicola | 46.71 | 5e-47 | 159 |
| LLPS-Fuo-1015 | Fusarium oxysporum | 46.58 | 7e-44 | 151 |
| LLPS-Orbr-1007 | Oryza brachyantha | 46.47 | 2e-46 | 158 |
| LLPS-Miv-0992 | Microbotryum violaceum | 46.39 | 9e-43 | 152 |
| LLPS-Cus-2068 | Cucumis sativus | 46.39 | 4e-43 | 149 |
| LLPS-Mae-0299 | Manihot esculenta | 46.34 | 9e-45 | 153 |
| LLPS-Phv-0905 | Phaseolus vulgaris | 46.34 | 1e-44 | 153 |
| LLPS-Beb-1276 | Beauveria bassiana | 46.34 | 2e-46 | 158 |
| LLPS-Fuv-1435 | Fusarium verticillioides | 46.34 | 1e-44 | 153 |
| LLPS-Via-0512 | Vigna angularis | 46.34 | 5e-45 | 154 |
| LLPS-Mao-1533 | Magnaporthe oryzae | 46.24 | 6e-48 | 162 |
| LLPS-Mua-2169 | Musa acuminata | 46.24 | 7e-48 | 161 |
| LLPS-Phn-1075 | Phaeosphaeria nodorum | 46.11 | 3e-45 | 155 |
| LLPS-Php-0576 | Physcomitrella patens | 46.03 | 4e-47 | 159 |
| LLPS-Map-1409 | Magnaporthe poae | 45.98 | 4e-46 | 157 |
| LLPS-Gag-0855 | Gaeumannomyces graminis | 45.98 | 1e-46 | 159 |
| LLPS-Pytr-1493 | Pyrenophora triticirepentis | 45.76 | 5e-48 | 162 |
| LLPS-Pyt-1157 | Pyrenophora teres | 45.76 | 4e-48 | 162 |
| LLPS-Coc-0266 | Corchorus capsularis | 45.73 | 1e-44 | 153 |
| LLPS-Thc-2491 | Theobroma cacao | 45.73 | 3e-44 | 152 |
| LLPS-Orgl-2052 | Oryza glumaepatula | 45.45 | 3e-38 | 136 |
| LLPS-Kop-0010 | Komagataella pastoris | 45.29 | 1e-36 | 132 |
| LLPS-Aso-0699 | Aspergillus oryzae | 45.29 | 2e-41 | 145 |
| LLPS-Mel-0111 | Melampsora laricipopulina | 45.18 | 9e-43 | 148 |
| LLPS-Pot-2704 | Populus trichocarpa | 45.14 | 4e-44 | 152 |
| LLPS-Gor-2541 | Gossypium raimondii | 45.12 | 2e-43 | 150 |
| LLPS-Hov-0114 | Hordeum vulgare | 45.09 | 2e-44 | 153 |
| LLPS-Zem-1881 | Zea mays | 45.08 | 1e-47 | 160 |
| LLPS-Trv-0702 | Trichoderma virens | 45.05 | 5e-48 | 162 |
| LLPS-Nef-1475 | Neosartorya fischeri | 45.03 | 3e-44 | 152 |
| LLPS-Nia-1893 | Nicotiana attenuata | 44.89 | 6e-45 | 153 |
| LLPS-Ast-0256 | Aspergillus terreus | 44.77 | 2e-41 | 145 |
| LLPS-Brd-0484 | Brachypodium distachyon | 44.77 | 7e-44 | 151 |
| LLPS-Tra-1573 | Triticum aestivum | 44.71 | 1e-44 | 153 |
| LLPS-Sol-1091 | Solanum lycopersicum | 44.7 | 4e-33 | 121 |
| LLPS-Art-2479 | Arabidopsis thaliana | 44.51 | 2e-43 | 150 |
| LLPS-Pug-0444 | Puccinia graminis | 44.51 | 4e-43 | 149 |
| LLPS-Dos-0857 | Dothistroma septosporum | 44.44 | 3e-44 | 152 |
| LLPS-Asg-1536 | Ashbya gossypii | 44.31 | 6e-37 | 133 |
| LLPS-Zyt-1479 | Zymoseptoria tritici | 44.31 | 9e-41 | 143 |
| LLPS-Orm-0296 | Oryza meridionalis | 44.2 | 6e-43 | 149 |
| LLPS-Asc-1694 | Aspergillus clavatus | 44.2 | 2e-44 | 153 |
| LLPS-Blg-0858 | Blumeria graminis | 44.2 | 1e-42 | 147 |
| LLPS-Yal-1149 | Yarrowia lipolytica | 44.17 | 7e-39 | 138 |
| LLPS-Scc-1473 | Schizosaccharomyces cryophilus | 44.1 | 2e-35 | 128 |
| LLPS-Put-1327 | Puccinia triticina | 43.98 | 2e-42 | 147 |
| LLPS-Arl-0722 | Arabidopsis lyrata | 43.9 | 3e-43 | 149 |
| LLPS-Glm-1736 | Glycine max | 43.68 | 1e-44 | 153 |
| LLPS-Scp-1429 | Schizosaccharomyces pombe | 43.37 | 2e-33 | 123 |
| LLPS-Hea-0170 | Helianthus annuus | 43.35 | 2e-44 | 152 |
| LLPS-Sot-1061 | Solanum tuberosum | 43.35 | 3e-44 | 152 |
| LLPS-Viv-1946 | Vitis vinifera | 43.32 | 3e-44 | 152 |
| LLPS-Asfu-0489 | Aspergillus fumigatus | 43.05 | 4e-34 | 125 |
| LLPS-Sac-1216 | Saccharomyces cerevisiae | 42.77 | 2e-34 | 127 |
| LLPS-Brr-0133 | Brassica rapa | 42.68 | 4e-42 | 147 |
| LLPS-Brn-2960 | Brassica napus | 42.35 | 1e-42 | 148 |
| LLPS-Scj-1452 | Schizosaccharomyces japonicus | 42.29 | 2e-33 | 123 |
| LLPS-Tru-1909 | Triticum urartu | 42.22 | 3e-41 | 144 |
| LLPS-Bro-2664 | Brassica oleracea | 42.07 | 3e-41 | 144 |
| LLPS-Asf-0688 | Aspergillus flavus | 42.0 | 1e-29 | 116 |
| LLPS-Chc-0105 | Chondrus crispus | 40.68 | 2e-38 | 137 |
| LLPS-Cae-0436 | Caenorhabditis elegans | 40.34 | 1e-39 | 140 |
| LLPS-Gas-0783 | Galdieria sulphuraria | 39.88 | 9e-37 | 132 |
| LLPS-Crn-0936 | Cryptococcus neoformans | 38.97 | 7e-39 | 139 |
| LLPS-Chr-0693 | Chlamydomonas reinhardtii | 38.92 | 4e-36 | 130 |
| LLPS-Tum-1438 | Tuber melanosporum | 37.74 | 4e-18 | 82.0 |
| LLPS-Osl-1071 | Ostreococcus lucimarinus | 36.94 | 2e-29 | 112 |
| LLPS-Lem-1236 | Leptosphaeria maculans | 36.0 | 1e-17 | 80.5 |
| LLPS-Dac-1820 | Daucus carota | 34.41 | 1e-08 | 54.7 |
| LLPS-Cym-0780 | Cyanidioschyzon merolae | 33.73 | 2e-20 | 90.1 |