DrLLPS - Data resource of LLPS

LLPS-Hea-0170
PFD3

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Prefoldin subunit 3
Gene Name:	PFD3, HannXRQ_Chr17g0569361
Ensembl Gene:	HannXRQ_Chr17g0569361
Ensembl Protein:	OTF88104
Organism:	Helianthus annuus
Taxa ID:	4232
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0555	P61758	Client	Stress granule	45.61	1e-45	155

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	OTF88104	OTF88104
UniProt		A0A251RW80, A0A251RW80_HELAN
GeneBank	CM007906	OTF88104.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MATSSPPQIG SEVVAERRGI PAASFVKDVQ AYLNQLGLDV NNTLAFLQER LQQYKVVEMK 60 61 LLAQQRDLQA KIPDIEKCLD VVATLQAKKD SDEALLTDFE VSEGIYARAR IENADSVCLW 120 121 LGANVMLEYS CEEATTLLQN NLENAKASLE VLVADLQFLR DQVTITQVTI ARVYNWDVHQ 180 181 RRVKSTSSSQ DS 192
Nucleotide CDS Sequence (FASTA)
1 ATGGCTACAT CATCGCCGCC GCAGATCGGC AGTGAAGTGG TGGCCGAACG GCGGGGAATA 60 61 CCGGCGGCAT CTTTCGTCAA AGATGTGCAA GCTTATTTGA ATCAATTAGG GCTCGATGTT 120 121 AACAATACAC TCGCCTTTCT TCAAGAAAGG CTTCAGCAAT ACAAAGTGGT TGAGATGAAA 180 181 CTTCTTGCCC AGCAGAGAGA TCTTCAGGCG AAGATTCCAG ATATCGAGAA GTGCTTAGAC 240 241 GTTGTTGCTA CTTTACAAGC TAAGAAAGAC AGTGATGAGG CATTGCTTAC AGATTTTGAA 300 301 GTATCTGAAG GCATCTATGC CCGGGCCCGG ATCGAGAATG CAGATTCTGT GTGCTTATGG 360 361 TTGGGAGCAA ACGTAATGCT AGAGTACTCA TGTGAAGAGG CCACTACTCT GCTCCAGAAC 420 421 AACCTTGAGA ATGCAAAAGC CAGTTTAGAA GTACTAGTTG CTGATCTACA GTTCTTAAGA 480 481 GATCAAGTTA CCATTACACA GGTAACGATT GCTCGGGTCT ACAATTGGGA TGTCCATCAA 540 541 CGAAGAGTTA AAAGCACTTC TTCCTCACAA GATTCATGA 579

▼ KEYWORD

ID	Family
KW-0143	Chaperone
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005829	Cellular Component	Cytosol
GO:0016272	Cellular Component	Prefoldin complex
GO:0006457	Biological Process	Protein folding

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Dac-1820	Daucus carota	88.31	1e-41	142
LLPS-Sol-1091	Solanum lycopersicum	85.07	9e-80	241
LLPS-Ori-0913	Oryza indica	84.92	2e-72	222
LLPS-Orb-0811	Oryza barthii	84.85	2e-76	233
LLPS-Sob-2237	Sorghum bicolor	84.8	2e-103	303
LLPS-Met-0886	Medicago truncatula	84.62	5e-100	294
LLPS-Vir-1351	Vigna radiata	84.17	1e-68	214
LLPS-Nia-1893	Nicotiana attenuata	83.71	1e-107	313
LLPS-Orr-1408	Oryza rufipogon	83.63	9e-101	296
LLPS-Orp-0301	Oryza punctata	83.63	9e-101	296
LLPS-Ors-2366	Oryza sativa	83.63	9e-101	296
LLPS-Sei-1912	Setaria italica	83.63	2e-101	298
LLPS-Orni-2227	Oryza nivara	83.63	9e-101	296
LLPS-Sot-1061	Solanum tuberosum	83.24	1e-107	314
LLPS-Prp-1329	Prunus persica	82.86	2e-103	303
LLPS-Org-2046	Oryza glaberrima	82.52	8e-81	244
LLPS-Mae-0299	Manihot esculenta	82.51	2e-106	310
LLPS-Via-0512	Vigna angularis	82.29	7e-102	299
LLPS-Art-2479	Arabidopsis thaliana	81.82	2e-102	300
LLPS-Orbr-1007	Oryza brachyantha	81.71	4e-101	297
LLPS-Phv-0905	Phaseolus vulgaris	81.5	4e-101	297
LLPS-Arl-0722	Arabidopsis lyrata	81.25	6e-102	299
LLPS-Orgl-2052	Oryza glumaepatula	81.01	4e-88	263
LLPS-Coc-0266	Corchorus capsularis	80.98	9e-108	314
LLPS-Lep-0908	Leersia perrieri	80.46	7e-99	291
LLPS-Mua-2169	Musa acuminata	80.23	1e-102	301
LLPS-Pot-2704	Populus trichocarpa	80.22	6e-103	301
LLPS-Glm-1736	Glycine max	80.0	6e-101	296
LLPS-Zem-1881	Zea mays	79.78	5e-103	301
LLPS-Viv-1946	Vitis vinifera	79.69	6e-108	314
LLPS-Brr-0133	Brassica rapa	79.55	8e-101	296
LLPS-Hov-0114	Hordeum vulgare	79.53	8e-98	289
LLPS-Thc-2491	Theobroma cacao	79.27	9e-107	311
LLPS-Tra-1573	Triticum aestivum	79.19	1e-98	291
LLPS-Brn-2960	Brassica napus	78.98	1e-99	293
LLPS-Brd-0484	Brachypodium distachyon	78.74	5e-98	289
LLPS-Bro-2664	Brassica oleracea	78.41	7e-98	289
LLPS-Orm-0296	Oryza meridionalis	77.05	7e-95	282
LLPS-Cus-2068	Cucumis sativus	76.96	6e-99	291
LLPS-Gor-2541	Gossypium raimondii	76.68	2e-103	303
LLPS-Amt-1737	Amborella trichopoda	76.09	1e-97	288
LLPS-Tru-1909	Triticum urartu	74.32	1e-94	281
LLPS-Php-0576	Physcomitrella patens	66.67	9e-76	232
LLPS-Sem-0857	Selaginella moellendorffii	65.56	1e-72	224
LLPS-Abg-1477	Absidia glauca	59.38	3e-17	77.8
LLPS-Fuv-1435	Fusarium verticillioides	48.48	1e-45	156
LLPS-Fuo-1015	Fusarium oxysporum	47.85	1e-43	150
LLPS-Sah-0547	Sarcophilus harrisii	47.56	2e-45	155
LLPS-Usm-0924	Ustilago maydis	46.43	9e-44	157
LLPS-Nec-0645	Neurospora crassa	46.39	2e-40	144
LLPS-Sus-1203	Sus scrofa	46.34	1e-45	156
LLPS-Orc-3626	Oryctolagus cuniculus	46.07	4e-45	155
LLPS-Ved-1479	Verticillium dahliae	46.06	2e-41	144
LLPS-Trr-0547	Trichoderma reesei	46.01	1e-40	143
LLPS-Map-1409	Magnaporthe poae	46.01	1e-40	143
LLPS-Chs-1240	Chlorocebus sabaeus	45.78	1e-43	152
LLPS-Spr-1570	Sporisorium reilianum	45.76	2e-47	160
LLPS-Asc-1694	Aspergillus clavatus	45.76	4e-41	144
LLPS-Paa-4142	Papio anubis	45.73	2e-45	156
LLPS-Caj-3724	Callithrix jacchus	45.73	1e-45	155
LLPS-Cea-2219	Cercocebus atys	45.73	2e-45	156
LLPS-Nol-2834	Nomascus leucogenys	45.61	1e-45	155
LLPS-Mam-4616	Macaca mulatta	45.61	1e-45	155
LLPS-Poa-3596	Pongo abelii	45.61	1e-45	155
LLPS-Man-3236	Macaca nemestrina	45.61	1e-45	155
LLPS-Hos-0555	Homo sapiens	45.61	1e-45	155
LLPS-Pat-3142	Pan troglodytes	45.61	1e-45	155
LLPS-Pap-1643	Pan paniscus	45.61	1e-45	155
LLPS-Mal-1787	Mandrillus leucophaeus	45.61	1e-45	155
LLPS-Gog-1861	Gorilla gorilla	45.61	1e-45	155
LLPS-Maf-1328	Macaca fascicularis	45.61	1e-45	155
LLPS-Mum-4073	Mus musculus	45.61	1e-45	155
LLPS-Fus-0565	Fusarium solani	45.45	9e-39	138
LLPS-Beb-1276	Beauveria bassiana	45.45	1e-42	148
LLPS-Myl-2125	Myotis lucifugus	45.45	1e-43	150
LLPS-Coo-1605	Colletotrichum orbiculare	45.45	5e-42	146
LLPS-Trv-0702	Trichoderma virens	45.4	1e-39	140
LLPS-Gag-0855	Gaeumannomyces graminis	45.4	1e-39	140
LLPS-Urm-1628	Ursus maritimus	45.33	4e-39	137
LLPS-Dar-3929	Danio rerio	45.12	2e-43	149
LLPS-Gaa-2723	Gasterosteus aculeatus	45.12	8e-43	148
LLPS-Icp-2754	Ictalurus punctatus	45.12	2e-44	152
LLPS-Fud-0979	Fukomys damarensis	45.09	2e-45	155
LLPS-Ict-3866	Ictidomys tridecemlineatus	45.03	4e-46	157
LLPS-Asn-0121	Aspergillus nidulans	44.97	1e-38	137
LLPS-Nef-1475	Neosartorya fischeri	44.94	4e-40	141
LLPS-Cogr-0992	Colletotrichum graminicola	44.85	9e-42	145
LLPS-Anc-3584	Anolis carolinensis	44.51	2e-45	155
LLPS-Otg-0664	Otolemur garnettii	44.44	6e-38	135
LLPS-Ran-1786	Rattus norvegicus	44.38	2e-38	137
LLPS-Leo-1983	Lepisosteus oculatus	44.26	2e-45	155
LLPS-Orn-0484	Oreochromis niloticus	44.25	2e-44	152
LLPS-Scf-2814	Scleropages formosus	44.25	2e-45	155
LLPS-Mao-1533	Magnaporthe oryzae	44.24	3e-41	144
LLPS-Gaga-3288	Gallus gallus	44.22	6e-39	137
LLPS-Pof-2098	Poecilia formosa	44.13	1e-41	145
LLPS-Asfu-0489	Aspergillus fumigatus	44.08	9e-31	116
LLPS-Ast-0256	Aspergillus terreus	44.07	1e-38	137
LLPS-Blg-0858	Blumeria graminis	43.98	1e-37	135
LLPS-Tag-2291	Taeniopygia guttata	43.93	5e-47	159
LLPS-Cas-1705	Carlito syrichta	43.93	3e-45	154
LLPS-Cap-2047	Cavia porcellus	43.93	9e-46	155
LLPS-Eqc-0808	Equus caballus	43.93	8e-46	156
LLPS-Caf-3695	Canis familiaris	43.93	1e-45	155
LLPS-Fia-2828	Ficedula albicollis	43.93	2e-46	159
LLPS-Mup-2383	Mustela putorius furo	43.93	8e-46	156
LLPS-Tut-1608	Tursiops truncatus	43.93	9e-46	155
LLPS-Cog-0986	Colletotrichum gloeosporioides	43.72	2e-43	150
LLPS-Dos-0857	Dothistroma septosporum	43.68	1e-38	137
LLPS-Yal-1149	Yarrowia lipolytica	43.65	1e-40	142
LLPS-Kop-0010	Komagataella pastoris	43.6	7e-37	132
LLPS-Asni-0269	Aspergillus niger	43.45	2e-31	117
LLPS-Pytr-1493	Pyrenophora triticirepentis	43.35	7e-41	143
LLPS-Fec-2707	Felis catus	43.35	4e-45	154
LLPS-Ova-1562	Ovis aries	43.35	2e-44	152
LLPS-Bot-3970	Bos taurus	43.35	2e-44	152
LLPS-Mea-1808	Mesocricetus auratus	43.35	2e-45	155
LLPS-Pes-3587	Pelodiscus sinensis	43.29	2e-41	144
LLPS-Aon-4066	Aotus nancymaae	43.29	5e-42	146
LLPS-Aim-2086	Ailuropoda melanoleuca	43.27	1e-41	145
LLPS-Asg-1536	Ashbya gossypii	43.27	4e-36	130
LLPS-Ora-3123	Ornithorhynchus anatinus	43.06	5e-33	121
LLPS-Phn-1075	Phaeosphaeria nodorum	43.03	4e-38	136
LLPS-Mel-0111	Melampsora laricipopulina	43.03	3e-41	144
LLPS-Cii-2299	Ciona intestinalis	42.86	2e-43	150
LLPS-Pyt-1157	Pyrenophora teres	42.77	3e-40	141
LLPS-Xet-2986	Xenopus tropicalis	42.7	3e-46	157
LLPS-Orl-4003	Oryzias latipes	42.62	3e-44	152
LLPS-Loa-3569	Loxodonta africana	42.53	1e-42	148
LLPS-Miv-0992	Microbotryum violaceum	42.42	4e-39	142
LLPS-Tar-3876	Takifugu rubripes	42.41	8e-39	138
LLPS-Aso-0699	Aspergillus oryzae	42.27	6e-40	141
LLPS-Asm-4015	Astyanax mexicanus	41.98	3e-37	134
LLPS-Chr-0693	Chlamydomonas reinhardtii	41.95	2e-39	139
LLPS-Meg-1915	Meleagris gallopavo	41.92	5e-41	142
LLPS-Zyt-1479	Zymoseptoria tritici	41.71	1e-38	137
LLPS-Lac-1705	Latimeria chalumnae	41.21	3e-43	149
LLPS-Asf-0688	Aspergillus flavus	41.07	3e-29	115
LLPS-Scj-1452	Schizosaccharomyces japonicus	40.96	1e-32	121
LLPS-Anp-0765	Anas platyrhynchos	40.8	7e-40	140
LLPS-Gas-0783	Galdieria sulphuraria	40.76	3e-33	123
LLPS-Dio-3278	Dipodomys ordii	40.46	3e-38	136
LLPS-Ten-3499	Tetraodon nigroviridis	40.0	2e-35	129
LLPS-Scc-1473	Schizosaccharomyces cryophilus	39.76	5e-32	119
LLPS-Chc-0105	Chondrus crispus	39.43	2e-32	122
LLPS-Scp-1429	Schizosaccharomyces pombe	39.16	3e-28	109
LLPS-Pug-0444	Puccinia graminis	38.1	3e-41	144
LLPS-Put-1327	Puccinia triticina	37.5	2e-39	139
LLPS-Rhb-1684	Rhinopithecus bieti	37.5	1e-27	108
LLPS-Sac-1216	Saccharomyces cerevisiae	37.36	4e-31	118
LLPS-Drm-1995	Drosophila melanogaster	36.97	2e-30	115
LLPS-Cae-0436	Caenorhabditis elegans	35.76	2e-35	129
LLPS-Osl-1071	Ostreococcus lucimarinus	35.29	3e-26	104
LLPS-Crn-0936	Cryptococcus neoformans	34.16	3e-31	119
LLPS-Cym-0780	Cyanidioschyzon merolae	33.33	4e-20	89.0
LLPS-Tum-1438	Tuber melanosporum	33.1	1e-17	80.5
LLPS-Lem-1236	Leptosphaeria maculans	33.08	2e-11	62.8

LLPS-Hea-0170PFD3

Protein Sequence

Nucleotide Sequence

LLPS-Hea-0170
PFD3