DrLLPS - Data resource of LLPS

LLPS-Kop-0010
PAS_chr1-4_0351

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Prefoldin subunit 3
Gene Name:	PAS_chr1-4_0351
Ensembl Gene:	PAS_chr1-4_0351
Ensembl Protein:	CAY68193
Organism:	Komagataella pastoris
Taxa ID:	644223
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0555	P61758	Client	Stress granule	44.71	3e-37	134

▼ FUNCTION

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	CAY68193	CAY68193
UniProt		C4QY70, C4QY70_KOMPG
GeneBank	FN392319	CAY68193.1
RefSeq	XM_002490429.1	XP_002490474.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MDRLKTEQSN PRGIPQAKFI DRVESLLNPS TCTNEDVDQL LKECQTRLQQ YKFMEENKRL 60 61 ALNGNKSKIP NITKTLEMVQ YLKERKEEDD DEPLQTNYEL NETLYSKAEI DVQNLDNVYL 120 121 WLGADVMMEY PLDEAIELLT TRLAVAKEAV TVAEEDLEFL REQITTMEVN TARVYNWDIT 180 181 RRKGLAPK 188
Nucleotide CDS Sequence (FASTA)
1 ATGGACAGAC TCAAAACCGA ACAGTCGAAT CCTCGTGGTA TTCCTCAGGC CAAGTTCATA 60 61 GATCGTGTGG AATCTTTATT AAACCCGTCC ACATGCACTA ATGAGGATGT GGACCAGCTG 120 121 CTTAAAGAAT GCCAGACACG TCTTCAGCAG TACAAGTTTA TGGAAGAGAA CAAACGCCTA 180 181 GCACTGAACG GAAACAAGTC CAAGATTCCC AACATTACAA AAACTCTGGA AATGGTTCAA 240 241 TATTTAAAGG AGCGTAAAGA AGAGGACGAT GACGAGCCCT TGCAGACTAA CTACGAATTG 300 301 AATGAAACCC TGTATAGCAA AGCCGAAATT GATGTTCAGA ATTTGGATAA CGTCTATTTG 360 361 TGGTTAGGAG CAGATGTTAT GATGGAGTAC CCACTAGATG AAGCCATTGA ACTCCTGACT 420 421 ACCAGACTAG CTGTGGCAAA AGAAGCTGTG ACAGTTGCTG AAGAAGACCT GGAGTTTTTG 480 481 AGAGAACAAA TCACTACCAT GGAAGTTAAT ACAGCCCGTG TCTACAATTG GGATATAACG 540 541 AGGAGGAAGG GGCTAGCACC CAAGTGA 567

▼ KEYWORD

ID	Family
KW-0143	Chaperone
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0016272	Cellular Component	Prefoldin complex
GO:0006457	Biological Process	Protein folding

▼ KEGG

ppa:PAS_chr1-4_0351

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Abg-1477	Absidia glauca	59.65	7e-14	68.2
LLPS-Usm-0924	Ustilago maydis	54.12	5e-49	172
LLPS-Asni-0269	Aspergillus niger	52.94	8e-43	147
LLPS-Spr-1570	Sporisorium reilianum	52.91	7e-51	169
LLPS-Cog-0986	Colletotrichum gloeosporioides	52.57	8e-51	169
LLPS-Pyt-1157	Pyrenophora teres	52.27	1e-49	166
LLPS-Map-1409	Magnaporthe poae	52.02	2e-48	163
LLPS-Gag-0855	Gaeumannomyces graminis	52.02	2e-48	163
LLPS-Pytr-1493	Pyrenophora triticirepentis	51.7	1e-49	166
LLPS-Fus-0565	Fusarium solani	51.45	1e-50	169
LLPS-Trv-0702	Trichoderma virens	51.45	6e-49	164
LLPS-Fuo-1015	Fusarium oxysporum	51.45	7e-49	164
LLPS-Phn-1075	Phaeosphaeria nodorum	51.43	2e-49	165
LLPS-Coo-1605	Colletotrichum orbiculare	51.43	5e-50	167
LLPS-Fuv-1435	Fusarium verticillioides	51.43	2e-50	167
LLPS-Ast-0256	Aspergillus terreus	51.12	6e-51	169
LLPS-Cogr-0992	Colletotrichum graminicola	50.86	4e-49	164
LLPS-Mao-1533	Magnaporthe oryzae	50.56	2e-47	160
LLPS-Trr-0547	Trichoderma reesei	50.29	5e-48	162
LLPS-Dos-0857	Dothistroma septosporum	50.27	7e-48	161
LLPS-Aso-0699	Aspergillus oryzae	50.0	2e-51	171
LLPS-Zyt-1479	Zymoseptoria tritici	49.72	6e-49	164
LLPS-Asn-0121	Aspergillus nidulans	49.43	2e-52	172
LLPS-Nec-0645	Neurospora crassa	49.13	3e-47	161
LLPS-Ved-1479	Verticillium dahliae	48.57	4e-45	154
LLPS-Blg-0858	Blumeria graminis	48.57	9e-47	158
LLPS-Yal-1149	Yarrowia lipolytica	48.54	2e-42	147
LLPS-Sac-1216	Saccharomyces cerevisiae	48.44	8e-47	158
LLPS-Asc-1694	Aspergillus clavatus	48.3	1e-47	160
LLPS-Asg-1536	Ashbya gossypii	47.59	2e-47	160
LLPS-Beb-1276	Beauveria bassiana	47.43	3e-47	159
LLPS-Scp-1429	Schizosaccharomyces pombe	47.43	6e-40	140
LLPS-Nef-1475	Neosartorya fischeri	47.19	2e-49	166
LLPS-Asf-0688	Aspergillus flavus	47.17	5e-39	141
LLPS-Urm-1628	Ursus maritimus	46.98	3e-30	114
LLPS-Aon-4066	Aotus nancymaae	46.98	1e-29	114
LLPS-Scc-1473	Schizosaccharomyces cryophilus	46.86	4e-41	143
LLPS-Pes-3587	Pelodiscus sinensis	46.31	2e-30	115
LLPS-Cap-2047	Cavia porcellus	45.88	8e-35	127
LLPS-Sah-0547	Sarcophilus harrisii	45.88	4e-35	128
LLPS-Gaga-3288	Gallus gallus	45.64	7e-30	113
LLPS-Asfu-0489	Aspergillus fumigatus	45.62	4e-39	138
LLPS-Orc-3626	Oryctolagus cuniculus	45.29	6e-34	126
LLPS-Fec-2707	Felis catus	45.29	3e-34	126
LLPS-Cas-1705	Carlito syrichta	45.29	2e-34	126
LLPS-Xet-2986	Xenopus tropicalis	45.29	7e-36	130
LLPS-Ict-3866	Ictidomys tridecemlineatus	45.29	1e-34	127
LLPS-Caf-3695	Canis familiaris	45.29	2e-34	126
LLPS-Eqc-0808	Equus caballus	45.29	2e-34	127
LLPS-Fud-0979	Fukomys damarensis	45.29	4e-34	125
LLPS-Sus-1203	Sus scrofa	45.29	3e-34	127
LLPS-Ova-1562	Ovis aries	45.29	5e-34	125
LLPS-Mup-2383	Mustela putorius furo	45.29	2e-34	126
LLPS-Tut-1608	Tursiops truncatus	45.29	1e-34	127
LLPS-Bot-3970	Bos taurus	45.29	5e-34	125
LLPS-Ora-3123	Ornithorhynchus anatinus	45.26	2e-22	93.6
LLPS-Nia-1893	Nicotiana attenuata	45.09	1e-34	126
LLPS-Leo-1983	Lepisosteus oculatus	45.09	3e-34	126
LLPS-Sol-1091	Solanum lycopersicum	44.92	6e-26	102
LLPS-Vir-1351	Vigna radiata	44.92	8e-25	100
LLPS-Meg-1915	Meleagris gallopavo	44.81	8e-30	113
LLPS-Pap-1643	Pan paniscus	44.71	3e-34	126
LLPS-Pat-3142	Pan troglodytes	44.71	3e-34	126
LLPS-Hos-0555	Homo sapiens	44.71	3e-34	126
LLPS-Man-3236	Macaca nemestrina	44.71	2e-34	126
LLPS-Loa-3569	Loxodonta africana	44.71	6e-34	125
LLPS-Nol-2834	Nomascus leucogenys	44.71	3e-34	126
LLPS-Anc-3584	Anolis carolinensis	44.71	2e-34	126
LLPS-Poa-3596	Pongo abelii	44.71	3e-34	126
LLPS-Mam-4616	Macaca mulatta	44.71	2e-34	126
LLPS-Gog-1861	Gorilla gorilla	44.71	3e-34	126
LLPS-Caj-3724	Callithrix jacchus	44.71	2e-34	126
LLPS-Mea-1808	Mesocricetus auratus	44.71	3e-34	125
LLPS-Maf-1328	Macaca fascicularis	44.71	2e-34	126
LLPS-Cea-2219	Cercocebus atys	44.71	5e-34	126
LLPS-Mal-1787	Mandrillus leucophaeus	44.71	2e-34	126
LLPS-Paa-4142	Papio anubis	44.71	5e-34	126
LLPS-Lac-1705	Latimeria chalumnae	44.57	6e-33	122
LLPS-Ori-0913	Oryza indica	44.54	2e-23	95.9
LLPS-Orn-0484	Oreochromis niloticus	44.51	3e-34	126
LLPS-Bro-2664	Brassica oleracea	44.51	9e-33	122
LLPS-Brr-0133	Brassica rapa	44.32	2e-32	121
LLPS-Brn-2960	Brassica napus	44.32	2e-32	121
LLPS-Scj-1452	Schizosaccharomyces japonicus	44.32	2e-33	122
LLPS-Zem-1881	Zea mays	44.25	2e-32	121
LLPS-Mel-0111	Melampsora laricipopulina	44.2	2e-36	132
LLPS-Arl-0722	Arabidopsis lyrata	44.19	3e-33	123
LLPS-Mae-0299	Manihot esculenta	43.93	2e-32	121
LLPS-Coc-0266	Corchorus capsularis	43.93	2e-33	123
LLPS-Mua-2169	Musa acuminata	43.93	2e-32	121
LLPS-Glm-1736	Glycine max	43.93	6e-33	122
LLPS-Via-0512	Vigna angularis	43.93	2e-33	124
LLPS-Fia-2828	Ficedula albicollis	43.82	2e-35	130
LLPS-Tag-2291	Taeniopygia guttata	43.82	7e-36	130
LLPS-Mum-4073	Mus musculus	43.72	8e-35	127
LLPS-Sei-1912	Setaria italica	43.68	4e-32	120
LLPS-Tra-1573	Triticum aestivum	43.68	5e-32	120
LLPS-Art-2479	Arabidopsis thaliana	43.6	1e-32	122
LLPS-Hea-0170	Helianthus annuus	43.6	3e-35	128
LLPS-Chs-1240	Chlorocebus sabaeus	43.6	6e-32	121
LLPS-Myl-2125	Myotis lucifugus	43.53	1e-32	121
LLPS-Aim-2086	Ailuropoda melanoleuca	43.53	4e-31	117
LLPS-Hov-0114	Hordeum vulgare	43.5	2e-32	121
LLPS-Dar-3929	Danio rerio	43.35	2e-33	123
LLPS-Pot-2704	Populus trichocarpa	43.35	7e-33	122
LLPS-Sem-0857	Selaginella moellendorffii	43.35	3e-30	115
LLPS-Orl-4003	Oryzias latipes	43.35	1e-33	124
LLPS-Anp-0765	Anas platyrhynchos	43.27	2e-30	115
LLPS-Miv-0992	Microbotryum violaceum	43.1	1e-39	144
LLPS-Thc-2491	Theobroma cacao	43.09	1e-32	121
LLPS-Otg-0664	Otolemur garnettii	43.04	4e-26	104
LLPS-Phv-0905	Phaseolus vulgaris	43.02	2e-33	124
LLPS-Gor-2541	Gossypium raimondii	43.02	3e-32	120
LLPS-Gaa-2723	Gasterosteus aculeatus	42.93	3e-35	128
LLPS-Amt-1737	Amborella trichopoda	42.78	1e-32	121
LLPS-Sob-2237	Sorghum bicolor	42.77	1e-32	121
LLPS-Pof-2098	Poecilia formosa	42.77	6e-31	117
LLPS-Icp-2754	Ictalurus punctatus	42.77	2e-33	124
LLPS-Scf-2814	Scleropages formosus	42.77	5e-33	122
LLPS-Rhb-1684	Rhinopithecus bieti	42.76	2e-19	85.9
LLPS-Org-2046	Oryza glaberrima	42.76	3e-27	106
LLPS-Put-1327	Puccinia triticina	42.7	6e-36	130
LLPS-Brd-0484	Brachypodium distachyon	42.61	4e-31	117
LLPS-Sot-1061	Solanum tuberosum	42.46	2e-34	126
LLPS-Prp-1329	Prunus persica	42.44	3e-33	123
LLPS-Php-0576	Physcomitrella patens	42.39	6e-34	124
LLPS-Dio-3278	Dipodomys ordii	42.35	4e-32	120
LLPS-Pug-0444	Puccinia graminis	42.22	2e-36	131
LLPS-Ors-2366	Oryza sativa	42.2	1e-31	119
LLPS-Orp-0301	Oryza punctata	42.2	1e-31	119
LLPS-Orr-1408	Oryza rufipogon	42.2	1e-31	119
LLPS-Orni-2227	Oryza nivara	42.2	1e-31	119
LLPS-Met-0886	Medicago truncatula	41.86	1e-30	116
LLPS-Cus-2068	Cucumis sativus	41.71	2e-35	129
LLPS-Lep-0908	Leersia perrieri	41.71	8e-31	117
LLPS-Orbr-1007	Oryza brachyantha	41.62	3e-31	118
LLPS-Asm-4015	Astyanax mexicanus	41.61	7e-25	101
LLPS-Tru-1909	Triticum urartu	41.53	6e-29	112
LLPS-Viv-1946	Vitis vinifera	41.4	3e-33	123
LLPS-Tar-3876	Takifugu rubripes	41.32	1e-29	114
LLPS-Orgl-2052	Oryza glumaepatula	41.14	1e-23	97.8
LLPS-Orb-0811	Oryza barthii	40.43	2e-24	99.4
LLPS-Ten-3499	Tetraodon nigroviridis	39.88	4e-28	110
LLPS-Crn-0936	Cryptococcus neoformans	39.71	7e-38	136
LLPS-Tum-1438	Tuber melanosporum	39.52	2e-22	93.6
LLPS-Drm-1995	Drosophila melanogaster	39.34	4e-29	112
LLPS-Ran-1786	Rattus norvegicus	39.33	3e-24	99.4
LLPS-Orm-0296	Oryza meridionalis	38.33	4e-26	104
LLPS-Lem-1236	Leptosphaeria maculans	38.02	7e-18	80.9
LLPS-Gas-0783	Galdieria sulphuraria	37.65	9e-24	98.2
LLPS-Osl-1071	Ostreococcus lucimarinus	36.05	2e-24	99.0
LLPS-Cii-2299	Ciona intestinalis	35.71	2e-25	102
LLPS-Cym-0780	Cyanidioschyzon merolae	34.69	3e-14	72.0
LLPS-Chr-0693	Chlamydomonas reinhardtii	34.1	4e-21	90.9
LLPS-Chc-0105	Chondrus crispus	33.15	4e-21	91.7
LLPS-Cae-0436	Caenorhabditis elegans	30.29	8e-19	84.7

LLPS-Kop-0010PAS_chr1-4_0351

Protein Sequence

Nucleotide Sequence

LLPS-Kop-0010
PAS_chr1-4_0351