• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scf-0211
Z043_114881

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Actin-related protein 2
Gene Name: Z043_114881
Ensembl Gene: ENSSFOG00015011048.1
Ensembl Protein: ENSSFOP00015017167.1
Organism: Scleropages formosus
Taxa ID: 113540
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDSKGRKVVV  CDNGTGFVKC  GYAGSNFPEH  IFPALVGRPI  IRSTAKVGNI  EIKDLMVGDE  60
61    ASELRSMLEV  NYPMENGIVR  NWDDMKHLWD  YTFGPEKLNI  DSRNCKILLT  EPPMNPTKNR  120
121   EKIIEVMFET  YQFAGVYIAI  QAVLTLYAQG  LLTGVVVDSG  DGVTHICPVY  EGFSLPHLTR  180
181   RLDIAGRDIT  RYLIKLLLLR  GYAFNHSADF  ETVRMMKEKL  CYVGYNIEQE  QKLALETTVL  240
241   VESYTLPDGR  VIKVGGERFE  APEALFQPHL  INVEGVGVAE  LLFNTIQAAD  IDTRAEFYKH  300
301   IVLSGGSTMY  PGLPSRLERE  LKQLYLERVL  KGDVEKLSKF  KIRIEDPPRR  KHMVFLGGAV  360
361   LADIMKDKDN  FWLTREEYQE  KGVRVLEKLG  VTVR  394
Nucleotide CDS Sequence (FASTA)
1     ATGGACAGTA  AAGGAAGGAA  AGTGGTGGTT  TGTGACAATG  GAACCGGGTT  TGTCAAGTGC  60
61    GGCTACGCTG  GCTCCAACTT  TCCCGAGCAC  ATCTTCCCCG  CTCTGGTCGG  CCGGCCCATC  120
121   ATCCGCTCAA  CGGCCAAAGT  GGGCAACATC  GAGATCAAGG  ACCTGATGGT  GGGTGACGAA  180
181   GCCAGCGAGC  TGCGCTCCAT  GCTGGAGGTA  AACTACCCCA  TGGAAAACGG  CATAGTGCGC  240
241   AACTGGGACG  ACATGAAGCA  CCTGTGGGAC  TACACCTTCG  GGCCTGAAAA  GCTCAACATC  300
301   GACTCACGCA  ACTGCAAGAT  CCTCCTCACA  GAGCCACCCA  TGAACCCCAC  CAAGAACCGG  360
361   GAGAAGATCA  TCGAGGTGAT  GTTTGAGACC  TATCAGTTTG  CCGGAGTTTA  CATCGCCATC  420
421   CAGGCAGTGC  TCACTCTGTA  TGCCCAGGGG  CTGCTGACCG  GCGTGGTGGT  CGACTCTGGC  480
481   GATGGTGTCA  CCCACATCTG  CCCCGTCTAC  GAGGGATTTT  CCCTGCCCCA  CCTGACCCGA  540
541   CGGCTGGACA  TTGCCGGGAG  GGACATCACG  CGCTACCTCA  TCAAGCTGCT  CCTTTTGCGT  600
601   GGCTACGCCT  TCAACCACTC  GGCCGACTTC  GAGACGGTGC  GCATGATGAA  GGAGAAGCTC  660
661   TGCTATGTGG  GCTACAACAT  TGAACAGGAG  CAGAAGCTGG  CGCTGGAGAC  TACGGTGCTC  720
721   GTGGAGTCCT  ACACGCTCCC  GGATGGCAGG  GTCATCAAGG  TGGGCGGGGA  GCGGTTTGAG  780
781   GCCCCCGAAG  CCTTGTTCCA  GCCTCACCTT  ATCAATGTGG  AGGGCGTTGG  CGTGGCTGAG  840
841   CTTCTCTTCA  ACACTATCCA  GGCGGCCGAC  ATCGACACCA  GGGCTGAGTT  CTACAAACAC  900
901   ATCGTCCTGT  CGGGGGGCTC  CACCATGTAC  CCCGGCCTCC  CGTCCCGGCT  GGAACGCGAG  960
961   CTAAAGCAGC  TCTACCTGGA  GCGAGTGCTG  AAAGGCGACG  TGGAAAAGCT  CTCGAAATTT  1020
1021  AAGATCCGGA  TTGAGGACCC  CCCTCGACGC  AAACACATGG  TGTTCCTGGG  TGGAGCCGTT  1080
1081  CTGGCCGACA  TCATGAAAGA  CAAGGACAAC  TTCTGGCTGA  CGCGTGAGGA  GTACCAGGAA  1140
1141  AAGGGCGTGC  GGGTCCTCGA  GAAGCTCGGT  GTCACGGTCA  GATAA  1185

▼ KEYWORD

ID
Family
Actin-binding
ATP-binding
Complete proteome
Cytoplasm
Cytoskeleton
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Arp2/3 protein complex
Molecular Function
ATP binding
Biological Process
Arp2/3 complex-mediated actin nucleation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tar-1249Takifugu rubripes99.490.0 774
LLPS-Orn-2641Oreochromis niloticus99.240.0 771
LLPS-Xim-0371Xiphophorus maculatus98.980.0 769
LLPS-Asm-2781Astyanax mexicanus98.980.0 771
LLPS-Orl-0960Oryzias latipes98.980.0 771
LLPS-Scm-1956Scophthalmus maximus98.730.0 767
LLPS-Dar-2598Danio rerio98.480.0 769
LLPS-Ten-0475Tetraodon nigroviridis98.220.0 759
LLPS-Pof-1032Poecilia formosa97.740.0 764
LLPS-Bot-2143Bos taurus97.350.0 731
LLPS-Tag-0326Taeniopygia guttata97.350.0 728
LLPS-Fia-1120Ficedula albicollis97.350.0 733
LLPS-Urm-1122Ursus maritimus97.350.0 653
LLPS-Anp-0538Anas platyrhynchos97.350.0 734
LLPS-Mup-1135Mustela putorius furo97.210.0 765
LLPS-Myl-0946Myotis lucifugus97.210.0 765
LLPS-Dio-0208Dipodomys ordii97.210.0 765
LLPS-Fud-1159Fukomys damarensis97.210.0 765
LLPS-Mum-0886Mus musculus97.210.0 765
LLPS-Poa-1599Pongo abelii97.210.0 765
LLPS-Orc-2077Oryctolagus cuniculus97.210.0 765
LLPS-Mod-0949Monodelphis domestica97.210.0 765
LLPS-Loa-1845Loxodonta africana97.210.0 765
LLPS-Ran-3046Rattus norvegicus96.950.0 763
LLPS-Gaga-0841Gallus gallus96.950.0 763
LLPS-Xet-0842Xenopus tropicalis96.950.0 762
LLPS-Lac-0674Latimeria chalumnae96.490.0 760
LLPS-Leo-0977Lepisosteus oculatus96.240.0 756
LLPS-Anc-2435Anolis carolinensis96.120.0 747
LLPS-Tut-1434Tursiops truncatus96.110.0 733
LLPS-Mal-0874Mandrillus leucophaeus95.990.0 760
LLPS-Paa-0923Papio anubis95.990.0 760
LLPS-Aim-0063Ailuropoda melanoleuca95.990.0 759
LLPS-Caj-3154Callithrix jacchus95.990.0 760
LLPS-Maf-0375Macaca fascicularis95.990.0 760
LLPS-Chs-1041Chlorocebus sabaeus95.990.0 760
LLPS-Cea-0940Cercocebus atys95.990.0 760
LLPS-Aon-0381Aotus nancymaae95.990.0 760
LLPS-Sus-2954Sus scrofa95.990.0 760
LLPS-Ict-2139Ictidomys tridecemlineatus95.990.0 760
LLPS-Nol-0179Nomascus leucogenys95.990.0 760
LLPS-Caf-0338Canis familiaris95.990.0 759
LLPS-Eqc-1931Equus caballus95.990.0 760
LLPS-Cap-0864Cavia porcellus95.990.0 760
LLPS-Mam-0896Macaca mulatta95.990.0 760
LLPS-Rhb-0923Rhinopithecus bieti95.990.0 760
LLPS-Pat-1378Pan troglodytes95.990.0 760
LLPS-Pap-0825Pan paniscus95.990.0 760
LLPS-Hos-1469Homo sapiens95.990.0 760
LLPS-Fec-2470Felis catus95.990.0 760
LLPS-Man-1249Macaca nemestrina95.990.0 760
LLPS-Pes-1675Pelodiscus sinensis95.630.0 744
LLPS-Gaa-0940Gasterosteus aculeatus95.440.0 763
LLPS-Ova-0070Ovis aries95.370.0 734
LLPS-Meg-1086Meleagris gallopavo94.960.0 743
LLPS-Cas-0800Carlito syrichta93.450.0 736
LLPS-Mea-1893Mesocricetus auratus92.650.0 692
LLPS-Sah-0309Sarcophilus harrisii91.720.0 560
LLPS-Gog-0156Gorilla gorilla90.610.0 690
LLPS-Ora-0030Ornithorhynchus anatinus85.560.0 635
LLPS-Cii-0739Ciona intestinalis83.82e-123 363
LLPS-Drm-0194Drosophila melanogaster82.230.0 660
LLPS-Cis-0996Ciona savignyi79.160.0 651
LLPS-Cae-0959Caenorhabditis elegans76.080.0 618
LLPS-Crn-0391Cryptococcus neoformans72.250.0 570
LLPS-Mel-0876Melampsora laricipopulina72.160.0 568
LLPS-Pug-0246Puccinia graminis71.320.0 560
LLPS-Abg-0467Absidia glauca70.910.0 578
LLPS-Put-0648Puccinia triticina70.80.0 560
LLPS-Scs-0248Sclerotinia sclerotiorum70.760.0 541
LLPS-Usm-0338Ustilago maydis70.510.0 553
LLPS-Spr-0010Sporisorium reilianum70.510.0 553
LLPS-Beb-0359Beauveria bassiana70.230.0 536
LLPS-Lem-0885Leptosphaeria maculans69.730.0 517
LLPS-Pyt-0334Pyrenophora teres69.450.0 537
LLPS-Pytr-0086Pyrenophora triticirepentis69.450.0 537
LLPS-Tum-0003Tuber melanosporum69.370.0 546
LLPS-Coo-0677Colletotrichum orbiculare69.270.0 535
LLPS-Blg-0688Blumeria graminis69.190.0 533
LLPS-Asf-0014Aspergillus flavus69.110.0 538
LLPS-Aso-0314Aspergillus oryzae69.110.0 538
LLPS-Asni-0938Aspergillus niger69.091e-156 452
LLPS-Map-0166Magnaporthe poae69.090.0 536
LLPS-Cogr-0833Colletotrichum graminicola69.010.0 530
LLPS-Mao-0676Magnaporthe oryzae68.970.0 534
LLPS-Ved-0527Verticillium dahliae68.930.0 529
LLPS-Trr-0719Trichoderma reesei68.850.0 530
LLPS-Gag-0643Gaeumannomyces graminis68.830.0 535
LLPS-Asfu-1032Aspergillus fumigatus68.750.0 537
LLPS-Nef-1075Neosartorya fischeri68.750.0 537
LLPS-Fuv-0243Fusarium verticillioides68.670.0 532
LLPS-Trv-0462Trichoderma virens68.670.0 529
LLPS-Fuo-0953Fusarium oxysporum68.670.0 532
LLPS-Fus-1028Fusarium solani68.670.0 531
LLPS-Nec-0806Neurospora crassa68.480.0 536
LLPS-Zyt-0550Zymoseptoria tritici68.410.0 535
LLPS-Asn-0032Aspergillus nidulans68.320.0 529
LLPS-Phn-0353Phaeosphaeria nodorum68.040.0 529
LLPS-Dos-0382Dothistroma septosporum67.890.0 529
LLPS-Scj-0713Schizosaccharomyces japonicus67.020.0 516
LLPS-Kop-0136Komagataella pastoris67.020.0 523
LLPS-Sac-0114Saccharomyces cerevisiae66.842e-179 512
LLPS-Scp-1109Schizosaccharomyces pombe66.497e-177 506
LLPS-Scc-0312Schizosaccharomyces cryophilus66.497e-179 511
LLPS-Yal-0669Yarrowia lipolytica66.060.0 521
LLPS-Ast-0087Aspergillus terreus65.410.0 521
LLPS-Php-0727Physcomitrella patens65.132e-178 510
LLPS-Asc-0361Aspergillus clavatus65.020.0 524
LLPS-Miv-0256Microbotryum violaceum64.775e-171 491
LLPS-Sot-0425Solanum tuberosum64.541e-161 467
LLPS-Amt-0492Amborella trichopoda64.541e-162 470
LLPS-Asg-1094Ashbya gossypii64.511e-174 500
LLPS-Coc-0083Corchorus capsularis64.482e-158 473
LLPS-Mua-0995Musa acuminata64.364e-175 501
LLPS-Sei-0609Setaria italica64.341e-174 501
LLPS-Zem-1335Zea mays64.348e-176 503
LLPS-Sob-0234Sorghum bicolor64.344e-175 501
LLPS-Vir-0186Vigna radiata64.295e-34 136
LLPS-Via-0018Vigna angularis64.242e-139 407
LLPS-Prp-0997Prunus persica64.164e-175 501
LLPS-Orp-1273Oryza punctata63.973e-173 496
LLPS-Hov-0082Hordeum vulgare63.911e-160 468
LLPS-Gor-2293Gossypium raimondii63.91e-173 497
LLPS-Sem-0836Selaginella moellendorffii63.82e-180 514
LLPS-Art-2034Arabidopsis thaliana63.752e-176 504
LLPS-Orb-1057Oryza barthii63.592e-173 497
LLPS-Org-1284Oryza glaberrima63.592e-173 497
LLPS-Orr-0662Oryza rufipogon63.592e-173 497
LLPS-Nia-1298Nicotiana attenuata63.594e-174 499
LLPS-Orgl-0332Oryza glumaepatula63.55e-173 496
LLPS-Mae-0639Manihot esculenta63.387e-174 498
LLPS-Orbr-0911Oryza brachyantha63.334e-173 496
LLPS-Arl-0396Arabidopsis lyrata63.243e-175 501
LLPS-Brn-0848Brassica napus63.241e-174 500
LLPS-Bro-0981Brassica oleracea63.242e-174 499
LLPS-Brr-0129Brassica rapa63.241e-174 500
LLPS-Thc-0560Theobroma cacao63.121e-172 495
LLPS-Tra-1245Triticum aestivum63.19e-166 478
LLPS-Lep-1331Leersia perrieri63.13e-162 481
LLPS-Tru-0391Triticum urartu63.13e-166 478
LLPS-Dac-0842Daucus carota63.084e-172 493
LLPS-Brd-0186Brachypodium distachyon63.051e-172 494
LLPS-Viv-0969Vitis vinifera63.051e-173 497
LLPS-Met-0809Medicago truncatula62.828e-173 495
LLPS-Glm-0625Glycine max62.564e-172 493
LLPS-Pot-0865Populus trichocarpa62.561e-172 494
LLPS-Sol-0820Solanum lycopersicum62.42e-157 476
LLPS-Hea-1538Helianthus annuus62.315e-172 493
LLPS-Cog-1541Colletotrichum gloeosporioides62.241e-161 466
LLPS-Orni-0226Oryza nivara61.232e-169 487
LLPS-Cus-0102Cucumis sativus60.524e-156 452
LLPS-Ori-1064Oryza indica59.742e-156 453
LLPS-Osl-0281Ostreococcus lucimarinus57.512e-153 446
LLPS-Chr-0170Chlamydomonas reinhardtii55.871e-154 449
LLPS-Ors-2347Oryza sativa46.771e-114 347
LLPS-Otg-1568Otolemur garnettii46.728e-114 344