• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Arl-0396
ARALYDRAFT_484485

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Actin-related protein 2
Gene Name: ARALYDRAFT_484485
Ensembl Gene: fgenesh2_kg.5__477__AT3G27000.1
Ensembl Protein: fgenesh2_kg.5__477__AT3G27000.1
Organism: Arabidopsis lyrata
Taxa ID: 81972
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MDNKNVVVCD  NGTGYVKCGF  AGENFPTSVF  PCVVGRPLLR  YEESLMEQQV  KDIVVGETCS  60
61    ELRHQLDINY  PVHNGIVQNW  EDMEHVWDHA  FYNELKINPS  ECKILLTDPP  LNPSKNREKM  120
121   IETMFEKYNF  AGIFIQIQAV  LTLYAQGLLT  GLVIDSGDGV  THVVPVVDGY  SFPHLTKRMN  180
181   VAGRHITAYL  VDLLSRRGYA  MNKTADFETV  REIKEKLCYI  SYDYKRESQL  GLETTILVKN  240
241   YTLPDGRVIK  VGTERFQAPE  ALFTPELIDV  EGDGMADMVF  RCIQEMDIDN  RMMLYQHIVL  300
301   SGGSTMYPGL  PSRLEKEIQD  RYLDTVLKGN  KDGLKKLRLR  IEDPPRRKHM  VYLGGAVLAG  360
361   IMKDAPEFWI  NREDYMEEGI  NCLNKMSQA  389
Nucleotide CDS Sequence (FASTA)
1     ATGGACAACA  AAAACGTCGT  CGTTTGTGAC  AACGGCACCG  GTTATGTCAA  ATGTGGATTT  60
61    GCTGGAGAGA  ATTTCCCAAC  GTCGGTTTTC  CCGTGTGTCG  TGGGAAGACC  GTTGCTTCGG  120
121   TATGAAGAAT  CACTCATGGA  GCAACAAGTC  AAGGATATAG  TTGTTGGGGA  GACTTGCTCT  180
181   GAGCTTCGAC  ATCAATTGGA  TATAAATTAT  CCTGTCCATA  ATGGTATTGT  GCAGAATTGG  240
241   GAGGATATGG  AACATGTTTG  GGATCATGCT  TTCTATAACG  AATTGAAAAT  CAATCCATCA  300
301   GAGTGTAAGA  TATTGCTCAC  AGATCCACCT  CTTAATCCCT  CCAAGAATCG  TGAAAAAATG  360
361   ATTGAGACAA  TGTTTGAGAA  ATACAATTTC  GCTGGCATTT  TCATTCAAAT  CCAAGCCGTT  420
421   TTGACTCTCT  ATGCTCAAGG  TTTGCTAACT  GGTTTGGTTA  TTGATTCTGG  TGATGGTGTT  480
481   ACTCATGTGG  TTCCGGTGGT  TGATGGCTAC  TCGTTCCCTC  ATCTTACCAA  AAGAATGAAT  540
541   GTTGCTGGCA  GACACATAAC  AGCGTATCTC  GTTGATCTAC  TATCTCGACG  AGGATATGCG  600
601   ATGAATAAAA  CGGCTGACTT  TGAGACGGTT  AGGGAAATTA  AAGAGAAGCT  CTGCTATATA  660
661   AGTTATGATT  ACAAGAGAGA  ATCTCAGCTT  GGCCTTGAGA  CAACCATCCT  TGTTAAGAAT  720
721   TATACTCTTC  CAGATGGGAG  AGTCATAAAA  GTAGGCACTG  AAAGATTCCA  AGCACCTGAA  780
781   GCGCTGTTTA  CACCGGAACT  CATTGATGTT  GAAGGTGATG  GAATGGCAGA  CATGGTTTTC  840
841   CGTTGTATTC  AAGAAATGGA  TATTGATAAC  CGCATGATGC  TCTACCAACA  CATAGTTTTA  900
901   AGCGGAGGAA  GCACCATGTA  CCCAGGATTA  CCTAGCCGTC  TTGAGAAGGA  AATCCAGGAT  960
961   CGGTATCTCG  ATACAGTTCT  AAAAGGAAAC  AAAGATGGCT  TGAAGAAACT  CAGATTGCGG  1020
1021  ATCGAAGATC  CACCGAGGAG  GAAACACATG  GTATACCTCG  GAGGTGCTGT  TCTTGCAGGA  1080
1081  ATCATGAAGG  ACGCACCAGA  ATTCTGGATC  AATAGAGAAG  ACTATATGGA  AGAAGGAATT  1140
1141  AATTGTTTGA  ATAAAATGAG  CCAAGCTTAA  1170

▼ KEYWORD

ID
Family
Actin-binding
ATP-binding
Complete proteome
Cytoplasm
Cytoskeleton
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Arp2/3 protein complex
Molecular Function
ATP binding
Biological Process
Arp2/3 complex-mediated actin nucleation
Biological Process
Multidimensional cell growth
Biological Process
Trichome morphogenesis

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Art-2034Arabidopsis thaliana99.230.0 807
LLPS-Brn-0848Brassica napus98.710.0 802
LLPS-Brr-0129Brassica rapa98.710.0 802
LLPS-Bro-0981Brassica oleracea98.460.0 801
LLPS-Coc-0083Corchorus capsularis93.70.0 724
LLPS-Thc-0560Theobroma cacao92.80.0 764
LLPS-Vir-0186Vigna radiata92.712e-52 188
LLPS-Met-0809Medicago truncatula92.540.0 759
LLPS-Via-0018Vigna angularis92.330.0 618
LLPS-Prp-0997Prunus persica92.030.0 761
LLPS-Gor-2293Gossypium raimondii92.030.0 759
LLPS-Pot-0865Populus trichocarpa92.030.0 758
LLPS-Mae-0639Manihot esculenta91.950.0 753
LLPS-Glm-0625Glycine max91.770.0 756
LLPS-Viv-0969Vitis vinifera91.770.0 758
LLPS-Amt-0492Amborella trichopoda91.740.0 702
LLPS-Sot-0425Solanum tuberosum91.180.0 699
LLPS-Dac-0842Daucus carota90.490.0 751
LLPS-Nia-1298Nicotiana attenuata90.490.0 750
LLPS-Hov-0082Hordeum vulgare89.810.0 691
LLPS-Sol-0820Solanum lycopersicum89.630.0 725
LLPS-Hea-1538Helianthus annuus89.610.0 733
LLPS-Mua-0995Musa acuminata89.460.0 739
LLPS-Zem-1335Zea mays89.20.0 740
LLPS-Sei-0609Setaria italica88.950.0 738
LLPS-Sob-0234Sorghum bicolor88.950.0 737
LLPS-Orbr-0911Oryza brachyantha88.690.0 737
LLPS-Tra-1245Triticum aestivum88.530.0 709
LLPS-Tru-0391Triticum urartu88.530.0 709
LLPS-Orgl-0332Oryza glumaepatula88.340.0 732
LLPS-Lep-1331Leersia perrieri88.270.0 716
LLPS-Orb-1057Oryza barthii88.170.0 734
LLPS-Org-1284Oryza glaberrima88.170.0 734
LLPS-Orr-0662Oryza rufipogon88.170.0 734
LLPS-Brd-0186Brachypodium distachyon87.920.0 733
LLPS-Orp-1273Oryza punctata87.920.0 733
LLPS-Cus-0102Cucumis sativus86.120.0 689
LLPS-Orni-0226Oryza nivara84.90.0 725
LLPS-Ori-1064Oryza indica83.80.0 682
LLPS-Sem-0836Selaginella moellendorffii80.570.0 684
LLPS-Php-0727Physcomitrella patens80.10.0 679
LLPS-Sah-0309Sarcophilus harrisii63.642e-136 400
LLPS-Urm-1122Ursus maritimus63.477e-162 465
LLPS-Xim-0371Xiphophorus maculatus63.380.0 533
LLPS-Tar-1249Takifugu rubripes63.380.0 535
LLPS-Orn-2641Oreochromis niloticus63.380.0 534
LLPS-Dar-2598Danio rerio63.380.0 534
LLPS-Asm-2781Astyanax mexicanus63.120.0 533
LLPS-Orl-0960Oryzias latipes63.120.0 535
LLPS-Ten-0475Tetraodon nigroviridis63.120.0 526
LLPS-Scf-0211Scleropages formosus63.080.0 535
LLPS-Scm-1956Scophthalmus maximus62.950.0 531
LLPS-Icp-1100Ictalurus punctatus62.860.0 532
LLPS-Leo-0977Lepisosteus oculatus62.560.0 530
LLPS-Pof-1032Poecilia formosa62.560.0 528
LLPS-Gaa-0940Gasterosteus aculeatus62.440.0 526
LLPS-Xet-0842Xenopus tropicalis62.340.0 529
LLPS-Ran-3046Rattus norvegicus62.240.0 531
LLPS-Lac-0674Latimeria chalumnae62.210.0 526
LLPS-Mup-1135Mustela putorius furo62.080.0 530
LLPS-Myl-0946Myotis lucifugus62.080.0 530
LLPS-Dio-0208Dipodomys ordii62.080.0 530
LLPS-Fud-1159Fukomys damarensis62.080.0 530
LLPS-Mum-0886Mus musculus62.080.0 530
LLPS-Gaga-0841Gallus gallus62.080.0 531
LLPS-Poa-1599Pongo abelii62.080.0 530
LLPS-Orc-2077Oryctolagus cuniculus62.080.0 530
LLPS-Mod-0949Monodelphis domestica62.080.0 530
LLPS-Loa-1845Loxodonta africana62.080.0 530
LLPS-Anc-2435Anolis carolinensis62.020.0 529
LLPS-Pes-3654Pelodiscus sinensis61.920.0 525
LLPS-Osl-0281Ostreococcus lucimarinus61.840.0 518
LLPS-Tag-0326Taeniopygia guttata61.666e-178 508
LLPS-Fia-1120Ficedula albicollis61.664e-179 511
LLPS-Anp-0538Anas platyrhynchos61.664e-179 511
LLPS-Bot-2143Bos taurus61.55e-178 509
LLPS-Abg-0467Absidia glauca61.40.0 520
LLPS-Mal-0874Mandrillus leucophaeus61.280.0 524
LLPS-Paa-0923Papio anubis61.280.0 524
LLPS-Aim-0063Ailuropoda melanoleuca61.280.0 524
LLPS-Caj-3154Callithrix jacchus61.280.0 524
LLPS-Maf-0375Macaca fascicularis61.280.0 524
LLPS-Chs-1041Chlorocebus sabaeus61.280.0 524
LLPS-Cea-0940Cercocebus atys61.280.0 524
LLPS-Aon-0381Aotus nancymaae61.280.0 524
LLPS-Sus-2954Sus scrofa61.280.0 524
LLPS-Ict-2139Ictidomys tridecemlineatus61.280.0 524
LLPS-Nol-0179Nomascus leucogenys61.280.0 524
LLPS-Caf-0338Canis familiaris61.280.0 524
LLPS-Eqc-1931Equus caballus61.280.0 524
LLPS-Cap-0864Cavia porcellus61.280.0 524
LLPS-Mam-0896Macaca mulatta61.280.0 524
LLPS-Rhb-0923Rhinopithecus bieti61.280.0 524
LLPS-Pat-1378Pan troglodytes61.280.0 524
LLPS-Pap-0825Pan paniscus61.280.0 524
LLPS-Hos-1469Homo sapiens61.280.0 524
LLPS-Fec-2470Felis catus61.280.0 524
LLPS-Man-1249Macaca nemestrina61.280.0 524
LLPS-Tut-1434Tursiops truncatus60.994e-179 511
LLPS-Ova-0070Ovis aries60.736e-178 511
LLPS-Meg-1086Meleagris gallopavo60.683e-180 514
LLPS-Cae-0959Caenorhabditis elegans60.470.0 516
LLPS-Chr-0170Chlamydomonas reinhardtii60.161e-180 515
LLPS-Drm-0194Drosophila melanogaster60.12e-177 507
LLPS-Mea-1893Mesocricetus auratus60.01e-171 492
LLPS-Cas-0800Carlito syrichta59.693e-179 512
LLPS-Mel-0876Melampsora laricipopulina59.642e-174 499
LLPS-Usm-0338Ustilago maydis59.543e-174 499
LLPS-Spr-0010Sporisorium reilianum59.543e-174 499
LLPS-Put-0648Puccinia triticina58.674e-171 491
LLPS-Pug-0246Puccinia graminis58.677e-171 491
LLPS-Crn-0391Cryptococcus neoformans58.13e-175 501
LLPS-Gog-0156Gorilla gorilla57.811e-163 472
LLPS-Lem-0885Leptosphaeria maculans57.491e-158 459
LLPS-Cis-0996Ciona savignyi57.361e-174 501
LLPS-Sac-0114Saccharomyces cerevisiae57.224e-167 481
LLPS-Tum-0003Tuber melanosporum57.033e-167 481
LLPS-Zyt-0550Zymoseptoria tritici56.962e-167 482
LLPS-Pyt-0334Pyrenophora teres56.968e-165 475
LLPS-Asg-1094Ashbya gossypii56.966e-165 475
LLPS-Pytr-0086Pyrenophora triticirepentis56.968e-165 475
LLPS-Dos-0382Dothistroma septosporum56.924e-168 483
LLPS-Kop-0136Komagataella pastoris56.841e-164 474
LLPS-Trr-0719Trichoderma reesei56.843e-165 476
LLPS-Map-0166Magnaporthe poae56.813e-166 478
LLPS-Mao-0676Magnaporthe oryzae56.77e-167 480
LLPS-Gag-0643Gaeumannomyces graminis56.561e-165 477
LLPS-Blg-0688Blumeria graminis56.432e-162 468
LLPS-Trv-0462Trichoderma virens56.439e-165 474
LLPS-Fuv-0243Fusarium verticillioides56.339e-167 480
LLPS-Fuo-0953Fusarium oxysporum56.339e-167 480
LLPS-Scs-0248Sclerotinia sclerotiorum56.172e-163 471
LLPS-Asni-0938Aspergillus niger56.128e-140 409
LLPS-Miv-0256Microbotryum violaceum55.97e-158 457
LLPS-Phn-0353Phaeosphaeria nodorum55.842e-161 466
LLPS-Beb-0359Beauveria bassiana55.814e-163 471
LLPS-Asf-0014Aspergillus flavus55.796e-164 473
LLPS-Aso-0314Aspergillus oryzae55.796e-164 473
LLPS-Yal-0669Yarrowia lipolytica55.731e-160 464
LLPS-Nec-0806Neurospora crassa55.585e-162 468
LLPS-Fus-1028Fusarium solani55.564e-164 473
LLPS-Ved-0527Verticillium dahliae55.383e-160 463
LLPS-Asfu-1032Aspergillus fumigatus55.353e-165 476
LLPS-Nef-1075Neosartorya fischeri55.353e-165 476
LLPS-Asn-0032Aspergillus nidulans55.02e-161 466
LLPS-Coo-0677Colletotrichum orbiculare54.643e-161 466
LLPS-Cogr-0833Colletotrichum graminicola54.644e-161 465
LLPS-Scc-0312Schizosaccharomyces cryophilus54.474e-158 458
LLPS-Ora-0030Ornithorhynchus anatinus54.267e-153 444
LLPS-Scp-1109Schizosaccharomyces pombe53.952e-155 451
LLPS-Scj-0713Schizosaccharomyces japonicus53.423e-154 448
LLPS-Ast-0087Aspergillus terreus53.156e-159 461
LLPS-Asc-0361Aspergillus clavatus52.352e-159 462
LLPS-Cog-1541Colletotrichum gloeosporioides49.617e-138 405
LLPS-Cii-2055Ciona intestinalis44.533e-121 363
LLPS-Otg-1568Otolemur garnettii44.532e-121 363