• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Bro-0011
106332409

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase 2
Gene Name: 106332409
Ensembl Gene: Bo3g037150
Ensembl Protein: Bo3g037150.1
Organism: Brassica oleracea
Taxa ID: 109376
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblBo3g037150.1Bo3g037150.1
UniProtA0A0D3B6P0, A0A0D3B6P0_BRAOL
RefSeqXM_013770870.1XP_013626324.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MEIEKLDVEA  SMEESGGVES  SNGKEALLAS  DLSENLDLDE  DEKENNQEEE  GSKAESSTKK  60
61    KKKKSKNKKK  KKKSSLQQTD  PPSIPVIDLF  PSGEFPEGEI  QEYKDDNLWR  TTSEEKREME  120
121   RLQKPIYNSL  RQAAEVHRQV  RKYMRSIMKP  GMLMIDICET  LENTVRKLIS  ENGLQAGIAF  180
181   PTGCSLNNVA  AHWTPNSGDK  TVLQYDDVMK  LDFGTHIDGY  IVDSAFTVAF  NPMYDPLLAA  240
241   SREATYTGIK  EAGVDVRLCD  VGAAIQEVME  SYEVEINGKV  YQVKSLRNLN  GHSIGRYQIH  300
301   ADKYVPNVKG  GEQTKMEEGE  LYAIETFGST  GKGYVRDDLE  CSHYMKNFDV  GHVPLRLPRA  360
361   KQLLATINKN  FSTLAFCRRY  LDRLGETKYL  MALKNLCDSG  IIEPCPPLCD  VKGSYISQFE  420
421   HTILLRPTCK  EVISKGDDY  439
Nucleotide CDS Sequence (FASTA)
1     ATGGAGATTG  AAAAGCTTGA  TGTGGAAGCT  TCTATGGAGG  AGAGTGGTGG  AGTAGAGTCC  60
61    TCTAATGGAA  AAGAGGCTCT  ATTAGCTTCA  GACCTTTCTG  AGAATCTTGA  TCTTGATGAA  120
121   GATGAAAAGG  AGAATAACCA  AGAAGAAGAG  GGAAGCAAAG  CTGAGTCTTC  AACGAAGAAA  180
181   AAGAAGAAGA  AAAGTAAAAA  CAAGAAGAAG  AAGAAGAAGA  GTTCTCTTCA  ACAGACTGAT  240
241   CCACCTTCAA  TTCCTGTTAT  TGATCTCTTC  CCTTCTGGAG  AATTCCCTGA  AGGTGAAATC  300
301   CAAGAGTACA  AGGACGATAA  TCTGTGGAGA  ACAACATCTG  AAGAGAAGAG  AGAGATGGAG  360
361   CGGCTACAAA  AGCCTATATA  CAACTCTCTG  CGCCAAGCAG  CAGAGGTTCA  TCGTCAAGTT  420
421   AGGAAGTATA  TGAGAAGCAT  AATGAAGCCT  GGAATGTTGA  TGATTGATAT  CTGTGAGACC  480
481   TTAGAGAACA  CTGTTCGTAA  GTTGATATCA  GAGAATGGTC  TTCAAGCTGG  TATCGCCTTC  540
541   CCTACAGGAT  GTTCTCTTAA  TAACGTTGCT  GCTCATTGGA  CACCAAACTC  TGGAGACAAG  600
601   ACTGTTCTTC  AGTATGATGA  TGTGATGAAG  CTAGATTTTG  GAACACATAT  TGATGGGTAC  660
661   ATTGTTGATT  CTGCTTTTAC  AGTTGCATTC  AATCCTATGT  ATGATCCTCT  TTTAGCAGCC  720
721   TCCCGTGAAG  CAACATACAC  CGGTATCAAG  GAAGCTGGAG  TTGATGTCCG  TCTTTGTGAT  780
781   GTTGGTGCTG  CAATTCAGGA  GGTCATGGAG  TCTTATGAGG  TAGAGATCAA  TGGAAAAGTC  840
841   TACCAAGTGA  AAAGTCTCAG  AAACCTGAAT  GGGCACAGCA  TTGGGCGCTA  TCAGATACAT  900
901   GCTGACAAAT  ATGTTCCTAA  TGTCAAAGGA  GGTGAGCAGA  CAAAGATGGA  AGAGGGTGAA  960
961   CTATATGCCA  TTGAAACTTT  TGGATCAACC  GGGAAAGGAT  ATGTGAGAGA  TGACTTAGAA  1020
1021  TGTAGCCATT  ACATGAAAAA  CTTCGATGTG  GGTCATGTCC  CTCTGAGGTT  ACCAAGAGCT  1080
1081  AAACAACTCC  TTGCAACCAT  TAACAAGAAC  TTCTCCACTC  TAGCCTTCTG  CAGACGCTAT  1140
1141  TTGGACCGTC  TTGGTGAAAC  TAAATACTTA  ATGGCTTTAA  AGAATCTGTG  TGATTCTGGC  1200
1201  ATCATTGAGC  CATGCCCTCC  ATTGTGCGAT  GTGAAAGGAA  GCTATATTTC  TCAGTTTGAG  1260
1261  CATACTATCT  TGCTGCGGCC  AACTTGCAAA  GAGGTTATTT  CCAAAGGAGA  CGATTACTGA  1320

▼ KEYWORD

ID
Family
Aminopeptidase
Coiled coil
Complete proteome
Cytoplasm
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Arl-0017Arabidopsis lyrata95.330.0 743
LLPS-Brr-1286Brassica rapa95.230.0 785
LLPS-Art-0404Arabidopsis thaliana91.180.0 712
LLPS-Met-0403Medicago truncatula90.930.0 707
LLPS-Vir-0061Vigna radiata90.380.0 705
LLPS-Mae-0126Manihot esculenta90.380.0 686
LLPS-Brn-2492Brassica napus90.360.0 706
LLPS-Via-1916Vigna angularis90.328e-79 247
LLPS-Glm-0306Glycine max90.110.0 705
LLPS-Phv-1458Phaseolus vulgaris89.840.0 704
LLPS-Coc-1079Corchorus capsularis89.560.0 677
LLPS-Sol-1543Solanum lycopersicum89.530.0 673
LLPS-Viv-1516Vitis vinifera89.530.0 679
LLPS-Sot-1511Solanum tuberosum89.260.0 674
LLPS-Sei-0480Setaria italica88.740.0 692
LLPS-Cus-1888Cucumis sativus88.710.0 669
LLPS-Pot-1287Populus trichocarpa88.710.0 696
LLPS-Thc-1568Theobroma cacao88.460.0 670
LLPS-Gor-0754Gossypium raimondii88.460.0 694
LLPS-Hea-0020Helianthus annuus88.330.0 686
LLPS-Sob-0293Sorghum bicolor88.190.0 687
LLPS-Nia-2348Nicotiana attenuata88.150.0 667
LLPS-Dac-1645Daucus carota87.880.0 659
LLPS-Mua-1192Musa acuminata87.640.0 694
LLPS-Brd-2039Brachypodium distachyon87.640.0 684
LLPS-Tra-0129Triticum aestivum87.360.0 684
LLPS-Tru-1611Triticum urartu87.360.0 681
LLPS-Prp-0776Prunus persica87.290.0 687
LLPS-Orp-0913Oryza punctata87.090.0 686
LLPS-Ori-1165Oryza indica86.810.0 685
LLPS-Org-0576Oryza glaberrima86.810.0 685
LLPS-Orbr-0781Oryza brachyantha86.780.0 682
LLPS-Hov-0316Hordeum vulgare86.540.0 679
LLPS-Ors-0164Oryza sativa86.540.0 682
LLPS-Orr-1416Oryza rufipogon86.540.0 682
LLPS-Orni-0338Oryza nivara85.710.0 672
LLPS-Orgl-2117Oryza glumaepatula85.710.0 672
LLPS-Lep-2275Leersia perrieri85.440.0 666
LLPS-Sem-1152Selaginella moellendorffii84.570.0 642
LLPS-Amt-1869Amborella trichopoda84.450.0 590
LLPS-Orb-0524Oryza barthii83.860.0 677
LLPS-Orm-1742Oryza meridionalis83.380.0 641
LLPS-Php-1829Physcomitrella patens82.420.0 657
LLPS-Zem-0961Zea mays80.650.0 673
LLPS-Pes-1896Pelodiscus sinensis77.897e-171 489
LLPS-Mam-3627Macaca mulatta75.230.0 541
LLPS-Nol-1806Nomascus leucogenys74.920.0 541
LLPS-Chr-0401Chlamydomonas reinhardtii74.730.0 591
LLPS-Anc-3235Anolis carolinensis73.30.0 573
LLPS-Fia-1306Ficedula albicollis73.020.0 568
LLPS-Xet-3470Xenopus tropicalis73.020.0 570
LLPS-Gas-0008Galdieria sulphuraria72.930.0 535
LLPS-Sah-0877Sarcophilus harrisii72.750.0 570
LLPS-Tag-2976Taeniopygia guttata72.750.0 568
LLPS-Orc-2119Oryctolagus cuniculus72.480.0 570
LLPS-Cap-0800Cavia porcellus72.480.0 570
LLPS-Anp-1036Anas platyrhynchos72.280.0 562
LLPS-Gog-4136Gorilla gorilla72.210.0 572
LLPS-Fud-0843Fukomys damarensis72.210.0 570
LLPS-Caj-2622Callithrix jacchus72.210.0 571
LLPS-Mum-3099Mus musculus72.210.0 569
LLPS-Maf-1964Macaca fascicularis72.210.0 571
LLPS-Chs-4138Chlorocebus sabaeus72.210.0 571
LLPS-Ora-0965Ornithorhynchus anatinus72.210.0 568
LLPS-Aon-2125Aotus nancymaae72.210.0 571
LLPS-Cea-1023Cercocebus atys72.210.0 571
LLPS-Sus-2648Sus scrofa72.210.0 569
LLPS-Mal-0914Mandrillus leucophaeus72.210.0 571
LLPS-Paa-1906Papio anubis72.210.0 571
LLPS-Myl-1479Myotis lucifugus72.210.0 570
LLPS-Ova-0459Ovis aries72.210.0 569
LLPS-Aim-1965Ailuropoda melanoleuca72.210.0 569
LLPS-Mup-2168Mustela putorius furo72.210.0 569
LLPS-Bot-3755Bos taurus72.210.0 569
LLPS-Pap-2478Pan paniscus72.210.0 572
LLPS-Urm-2624Ursus maritimus72.210.0 569
LLPS-Pat-0957Pan troglodytes72.210.0 572
LLPS-Hos-0267Homo sapiens72.210.0 572
LLPS-Fec-2275Felis catus72.210.0 569
LLPS-Mod-0935Monodelphis domestica72.210.0 569
LLPS-Man-3185Macaca nemestrina72.210.0 571
LLPS-Gaga-1057Gallus gallus72.210.0 563
LLPS-Ict-3096Ictidomys tridecemlineatus72.210.0 570
LLPS-Caf-3192Canis familiaris72.210.0 569
LLPS-Poa-0781Pongo abelii72.210.0 570
LLPS-Eqc-3814Equus caballus72.210.0 569
LLPS-Meg-1216Meleagris gallopavo72.010.0 559
LLPS-Dio-0527Dipodomys ordii71.930.0 567
LLPS-Loa-2443Loxodonta africana71.930.0 566
LLPS-Cas-3492Carlito syrichta71.930.0 570
LLPS-Orl-2629Oryzias latipes71.660.0 568
LLPS-Xim-2080Xiphophorus maculatus71.660.0 565
LLPS-Orn-2497Oreochromis niloticus71.660.0 566
LLPS-Icp-1096Ictalurus punctatus71.390.0 561
LLPS-Tar-0070Takifugu rubripes71.390.0 558
LLPS-Gaa-0732Gasterosteus aculeatus71.120.0 557
LLPS-Scf-0970Scleropages formosus71.120.0 560
LLPS-Ten-2503Tetraodon nigroviridis71.120.0 560
LLPS-Tut-0263Tursiops truncatus70.840.0 545
LLPS-Scm-1244Scophthalmus maximus70.840.0 565
LLPS-Ran-1984Rattus norvegicus70.670.0 540
LLPS-Asm-1574Astyanax mexicanus70.570.0 555
LLPS-Dar-2650Danio rerio70.570.0 555
LLPS-Leo-2764Lepisosteus oculatus70.270.0 546
LLPS-Pof-0892Poecilia formosa69.760.0 553
LLPS-Cii-2283Ciona intestinalis68.380.0 547
LLPS-Drm-1540Drosophila melanogaster68.110.0 539
LLPS-Lac-0393Latimeria chalumnae67.80.0 548
LLPS-Cis-1734Ciona savignyi67.570.0 541
LLPS-Osl-0653Ostreococcus lucimarinus67.223e-176 507
LLPS-Otg-2950Otolemur garnettii66.043e-179 517
LLPS-Chc-1100Chondrus crispus65.932e-179 516
LLPS-Cym-0742Cyanidioschyzon merolae64.679e-171 495
LLPS-Abg-0767Absidia glauca64.464e-179 514
LLPS-Cae-0841Caenorhabditis elegans63.192e-166 484
LLPS-Scp-0507Schizosaccharomyces pombe62.261e-172 498
LLPS-Scj-0669Schizosaccharomyces japonicus62.151e-169 490
LLPS-Rhb-0061Rhinopithecus bieti62.137e-156 456
LLPS-Nef-0018Neosartorya fischeri61.967e-167 484
LLPS-Asni-0120Aspergillus niger61.681e-166 483
LLPS-Put-0170Puccinia triticina61.322e-100 312
LLPS-Asf-0832Aspergillus flavus61.147e-166 482
LLPS-Scc-0617Schizosaccharomyces cryophilus60.889e-169 488
LLPS-Ast-0814Aspergillus terreus60.872e-165 480
LLPS-Lem-1112Leptosphaeria maculans60.74e-165 480
LLPS-Zyt-0428Zymoseptoria tritici60.385e-161 470
LLPS-Trr-1246Trichoderma reesei60.285e-155 451
LLPS-Mea-4266Mesocricetus auratus60.162e-45 160
LLPS-Dos-0711Dothistroma septosporum60.112e-161 471
LLPS-Nec-0478Neurospora crassa59.783e-159 464
LLPS-Asc-0394Aspergillus clavatus59.713e-152 446
LLPS-Asn-0391Aspergillus nidulans59.573e-162 472
LLPS-Cog-0564Colletotrichum gloeosporioides59.511e-156 457
LLPS-Mao-1254Magnaporthe oryzae59.243e-159 464
LLPS-Pyt-0677Pyrenophora teres59.242e-161 470
LLPS-Fus-0810Fusarium solani59.247e-159 464
LLPS-Trv-0635Trichoderma virens59.246e-157 459
LLPS-Pytr-0486Pyrenophora triticirepentis59.246e-161 469
LLPS-Pug-0627Puccinia graminis59.192e-155 456
LLPS-Miv-1309Microbotryum violaceum59.092e-155 455
LLPS-Beb-1007Beauveria bassiana58.973e-156 457
LLPS-Ved-0285Verticillium dahliae58.978e-154 451
LLPS-Mel-0742Melampsora laricipopulina58.762e-148 437
LLPS-Phn-0291Phaeosphaeria nodorum58.764e-151 444
LLPS-Asfu-0160Aspergillus fumigatus58.724e-161 471
LLPS-Fuv-0788Fusarium verticillioides58.74e-155 454
LLPS-Gag-0741Gaeumannomyces graminis58.72e-157 460
LLPS-Cogr-0752Colletotrichum graminicola58.71e-156 458
LLPS-Fuo-0163Fusarium oxysporum58.74e-155 454
LLPS-Sac-1569Saccharomyces cerevisiae58.42e-142 421
LLPS-Blg-1368Blumeria graminis58.113e-153 449
LLPS-Kop-0038Komagataella pastoris57.924e-152 447
LLPS-Map-0081Magnaporthe poae57.751e-153 451
LLPS-Coo-1266Colletotrichum orbiculare57.343e-153 449
LLPS-Asg-0220Ashbya gossypii56.942e-134 398
LLPS-Usm-0536Ustilago maydis56.792e-141 416
LLPS-Yal-0788Yarrowia lipolytica56.335e-154 452
LLPS-Tum-0089Tuber melanosporum56.256e-148 435
LLPS-Spr-0684Sporisorium reilianum56.155e-145 429
LLPS-Crn-0326Cryptococcus neoformans54.692e-138 411
LLPS-Aso-0738Aspergillus oryzae52.795e-132 396