• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mel-0742
MELLADRAFT_46796

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase 2
Gene Name: MELLADRAFT_46796
Ensembl Gene: MELLADRAFT_46796
Ensembl Protein: EGG11404
Organism: Melampsora laricipopulina
Taxa ID: 747676
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEGG11404EGG11404
UniProtF4R7Z6, F4R7Z6_MELLP
GeneBankGL883092EGG11404.1
RefSeqXM_007404977.1XP_007405039.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAIEIATDGD  VTSNGQATGT  TGASEGITVP  SAEQTTLENH  EDDEDEEDGV  EEATAGNSGE  60
61    KKKKKKKKPK  KKKTNGACAQ  QSSPPRIPLS  KIYPHGNYPV  GETSAYLGDN  SYRTTSEEKR  120
121   HLELLAAQED  PESPDNYNSI  RRAAEAHRQV  RKYARENIKP  GMGMTEIAEM  IENGTRALIE  180
181   EDGQKRGIGF  PTGLSLNHCA  AHYTPNAGDN  IVLKADDVLK  VDFGIQVGGR  IVDSAFTMTF  240
241   NDKYDKLLEA  VKAATDTGVR  EAGIDARLQD  IGAKIQEVME  SYEVEVDGKV  HQVKSIKNLT  300
301   GHNILPYHIH  GGKSVPIVAD  SDEDGVMEEG  DHFAVETFGS  TGRGYVRDDG  ECSHYAKMPD  360
361   VIKPIPWNRS  KALLNTINKQ  FGTLPFCKRY  LDRIGETRYY  PALDKLVDLG  IVQDYPPLSD  420
421   VPGCMTAQFE  HTIIMRPTCK  EVVSRGDDY  449
Nucleotide CDS Sequence (FASTA)
1     ATGGCTATCG  AAATAGCCAC  CGATGGCGAT  GTCACTTCGA  ATGGCCAAGC  TACTGGCACG  60
61    ACTGGCGCAT  CCGAAGGGAT  AACAGTTCCT  TCTGCGGAAC  AAACGACTTT  AGAAAACCAC  120
121   GAAGATGACG  AAGACGAAGA  GGACGGTGTC  GAAGAGGCCA  CTGCCGGTAA  TTCGGGAGAA  180
181   AAGAAGAAGA  AAAAGAAGAA  GAAACCCAAG  AAAAAGAAAA  CAAATGGAGC  TTGTGCACAA  240
241   CAAAGCTCTC  CACCTCGAAT  CCCATTATCG  AAAATTTACC  CGCATGGTAA  TTACCCCGTG  300
301   GGTGAAACTT  CAGCTTATCT  AGGCGATAAT  TCTTACCGAA  CTACTTCAGA  AGAGAAAAGA  360
361   CATTTAGAAC  TCTTAGCAGC  TCAAGAAGAC  CCAGAATCAC  CAGATAATTA  TAATAGTATC  420
421   AGACGTGCGG  CCGAAGCACA  CCGACAAGTT  CGCAAATATG  CTCGTGAAAA  TATAAAACCT  480
481   GGTATGGGTA  TGACTGAAAT  TGCTGAAATG  ATTGAAAACG  GAACTCGGGC  TCTCATTGAG  540
541   GAAGATGGAC  AGAAAAGAGG  AATAGGTTTT  CCTACTGGGC  TCAGTCTTAA  TCATTGTGCT  600
601   GCTCATTATA  CACCCAACGC  AGGTGACAAC  ATTGTCTTGA  AAGCAGATGA  TGTCCTAAAG  660
661   GTGGACTTTG  GCATCCAAGT  CGGTGGTCGG  ATCGTGGATT  CAGCTTTTAC  TATGACGTTC  720
721   AATGACAAAT  ACGATAAGCT  ATTGGAAGCC  GTGAAAGCCG  CTACTGATAC  AGGTGTTCGA  780
781   GAAGCAGGCA  TTGACGCCAG  GCTCCAAGAC  ATCGGTGCCA  AGATACAAGA  GGTGATGGAA  840
841   TCTTACGAAG  TGGAAGTAGA  TGGCAAGGTG  CATCAAGTCA  AGTCAATCAA  AAATTTAACT  900
901   GGTCATAACA  TCCTTCCTTA  CCACATACAT  GGTGGTAAGT  CTGTACCCAT  CGTTGCTGAC  960
961   TCTGACGAGG  ATGGAGTCAT  GGAAGAGGGG  GATCATTTTG  CTGTTGAGAC  CTTTGGAAGT  1020
1021  ACGGGACGAG  GTTATGTGAG  AGATGATGGG  GAATGCTCAC  ATTACGCCAA  GATGCCCGAT  1080
1081  GTCATCAAGC  CAATCCCATG  GAATCGCTCC  AAGGCTTTGT  TAAATACTAT  CAATAAACAA  1140
1141  TTCGGCACCC  TCCCTTTTTG  TAAGAGGTAC  CTGGACCGTA  TAGGAGAGAC  CCGATATTAT  1200
1201  CCAGCGCTTG  ACAAGCTGGT  CGATCTAGGT  ATTGTCCAGG  ATTACCCGCC  ATTGAGCGAC  1260
1261  GTGCCAGGGT  GTATGACAGC  GCAGTTTGAG  CACACCATCA  TAATGAGGCC  CACGTGTAAG  1320
1321  GAGGTTGTTA  GTAGAGGGGA  CGACTATTGA  1350

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Cytoplasm
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Put-0170Puccinia triticina84.36e-146 429
LLPS-Pug-0627Puccinia graminis82.110.0 653
LLPS-Miv-1309Microbotryum violaceum68.780.0 535
LLPS-Scj-0669Schizosaccharomyces japonicus65.953e-171 494
LLPS-Scp-0507Schizosaccharomyces pombe65.57e-171 494
LLPS-Via-1916Vigna angularis65.321e-49 171
LLPS-Pes-1896Pelodiscus sinensis64.161e-130 386
LLPS-Kop-0038Komagataella pastoris62.846e-160 467
LLPS-Spr-0684Sporisorium reilianum62.673e-163 476
LLPS-Scc-0617Schizosaccharomyces cryophilus62.534e-162 472
LLPS-Abg-0767Absidia glauca61.892e-164 478
LLPS-Ved-0285Verticillium dahliae61.878e-160 466
LLPS-Usm-0536Ustilago maydis61.815e-156 454
LLPS-Mam-3627Macaca mulatta61.769e-143 423
LLPS-Beb-1007Beauveria bassiana61.76e-159 464
LLPS-Nol-1806Nomascus leucogenys61.471e-142 422
LLPS-Sei-0480Setaria italica61.466e-158 462
LLPS-Sob-0293Sorghum bicolor61.462e-158 463
LLPS-Nef-0018Neosartorya fischeri61.443e-159 465
LLPS-Hov-0316Hordeum vulgare61.192e-157 461
LLPS-Vir-0061Vigna radiata61.192e-155 457
LLPS-Glm-0306Glycine max61.191e-155 456
LLPS-Art-0404Arabidopsis thaliana61.192e-156 458
LLPS-Phv-1458Phaseolus vulgaris61.191e-155 455
LLPS-Ast-0814Aspergillus terreus61.018e-159 464
LLPS-Gas-0008Galdieria sulphuraria60.993e-152 446
LLPS-Crn-0326Cryptococcus neoformans60.982e-154 453
LLPS-Brd-2039Brachypodium distachyon60.922e-158 463
LLPS-Tra-0129Triticum aestivum60.921e-157 461
LLPS-Dac-1645Daucus carota60.922e-152 446
LLPS-Mua-1192Musa acuminata60.926e-157 459
LLPS-Met-0403Medicago truncatula60.751e-156 457
LLPS-Pot-1287Populus trichocarpa60.752e-156 457
LLPS-Brn-2613Brassica napus60.655e-154 451
LLPS-Tru-1611Triticum urartu60.651e-157 460
LLPS-Fus-0810Fusarium solani60.644e-156 457
LLPS-Sot-1511Solanum tuberosum60.383e-150 442
LLPS-Cus-1888Cucumis sativus60.384e-149 439
LLPS-Arl-1907Arabidopsis lyrata60.383e-149 439
LLPS-Bro-1313Brassica oleracea60.385e-154 451
LLPS-Brr-3062Brassica rapa60.383e-154 452
LLPS-Orp-0913Oryza punctata60.382e-156 458
LLPS-Trr-1246Trichoderma reesei60.332e-151 442
LLPS-Cogr-0752Colletotrichum graminicola60.272e-151 445
LLPS-Asc-0394Aspergillus clavatus60.117e-148 436
LLPS-Fuv-0788Fusarium verticillioides60.114e-157 459
LLPS-Ori-1165Oryza indica60.115e-156 457
LLPS-Orr-1416Oryza rufipogon60.113e-156 457
LLPS-Fuo-0163Fusarium oxysporum60.114e-157 459
LLPS-Org-0576Oryza glaberrima60.115e-156 457
LLPS-Ors-0164Oryza sativa60.115e-156 457
LLPS-Trv-0635Trichoderma virens60.03e-157 460
LLPS-Cog-0564Colletotrichum gloeosporioides60.02e-151 445
LLPS-Hea-0020Helianthus annuus59.951e-152 448
LLPS-Coc-1079Corchorus capsularis59.842e-149 440
LLPS-Gor-0754Gossypium raimondii59.843e-156 457
LLPS-Orbr-0781Oryza brachyantha59.841e-153 456
LLPS-Nia-2348Nicotiana attenuata59.841e-148 437
LLPS-Orn-2497Oreochromis niloticus59.731e-153 452
LLPS-Asf-0832Aspergillus flavus59.681e-152 448
LLPS-Asni-0120Aspergillus niger59.573e-153 449
LLPS-Mae-0126Manihot esculenta59.573e-147 434
LLPS-Drm-1540Drosophila melanogaster59.522e-153 450
LLPS-Scf-0970Scleropages formosus59.471e-150 444
LLPS-Xet-3470Xenopus tropicalis59.477e-151 445
LLPS-Anc-3235Anolis carolinensis59.476e-150 445
LLPS-Dar-3061Danio rerio59.472e-150 444
LLPS-Prp-0776Prunus persica59.461e-150 443
LLPS-Orgl-2117Oryza glumaepatula59.35e-152 447
LLPS-Lep-2275Leersia perrieri59.33e-151 444
LLPS-Orni-0338Oryza nivara59.35e-152 447
LLPS-Tar-3299Takifugu rubripes59.21e-152 449
LLPS-Gaga-1057Gallus gallus59.27e-149 440
LLPS-Orc-2119Oryctolagus cuniculus59.22e-150 444
LLPS-Asn-0391Aspergillus nidulans59.18e-154 451
LLPS-Lem-1112Leptosphaeria maculans59.041e-152 448
LLPS-Nec-0478Neurospora crassa59.042e-151 445
LLPS-Meg-1216Meleagris gallopavo59.041e-148 437
LLPS-Php-1829Physcomitrella patens59.032e-150 444
LLPS-Thc-1568Theobroma cacao59.039e-147 436
LLPS-Viv-1516Vitis vinifera59.031e-147 434
LLPS-Bot-3755Bos taurus58.938e-151 445
LLPS-Gaa-0732Gasterosteus aculeatus58.934e-151 443
LLPS-Ova-0459Ovis aries58.932e-150 444
LLPS-Myl-1479Myotis lucifugus58.939e-151 445
LLPS-Aim-1965Ailuropoda melanoleuca58.931e-150 444
LLPS-Mup-2168Mustela putorius furo58.931e-150 444
LLPS-Mum-3099Mus musculus58.932e-150 444
LLPS-Sah-0877Sarcophilus harrisii58.939e-151 442
LLPS-Sus-2648Sus scrofa58.931e-150 444
LLPS-Orl-2629Oryzias latipes58.933e-153 451
LLPS-Coo-1266Colletotrichum orbiculare58.938e-150 441
LLPS-Fud-0843Fukomys damarensis58.931e-150 444
LLPS-Asm-1574Astyanax mexicanus58.932e-148 441
LLPS-Eqc-3814Equus caballus58.932e-150 444
LLPS-Cap-0800Cavia porcellus58.933e-150 444
LLPS-Caf-3192Canis familiaris58.939e-151 445
LLPS-Ict-3096Ictidomys tridecemlineatus58.936e-151 445
LLPS-Fec-2275Felis catus58.931e-150 444
LLPS-Urm-2624Ursus maritimus58.931e-150 444
LLPS-Fia-1306Ficedula albicollis58.932e-150 442
LLPS-Chr-0401Chlamydomonas reinhardtii58.928e-149 441
LLPS-Gag-0741Gaeumannomyces graminis58.781e-151 446
LLPS-Mao-1254Magnaporthe oryzae58.789e-153 448
LLPS-Sol-1543Solanum lycopersicum58.763e-150 439
LLPS-Dio-0527Dipodomys ordii58.675e-150 442
LLPS-Paa-1906Papio anubis58.672e-149 441
LLPS-Mal-0914Mandrillus leucophaeus58.672e-149 441
LLPS-Chs-4138Chlorocebus sabaeus58.677e-150 441
LLPS-Maf-1964Macaca fascicularis58.672e-149 441
LLPS-Aon-2125Aotus nancymaae58.672e-149 441
LLPS-Cea-1023Cercocebus atys58.672e-149 441
LLPS-Gog-4136Gorilla gorilla58.672e-149 441
LLPS-Caj-2622Callithrix jacchus58.672e-149 441
LLPS-Ten-2503Tetraodon nigroviridis58.674e-149 440
LLPS-Poa-0781Pongo abelii58.672e-149 441
LLPS-Scm-1244Scophthalmus maximus58.671e-147 449
LLPS-Pap-2478Pan paniscus58.672e-149 441
LLPS-Pat-0957Pan troglodytes58.672e-149 441
LLPS-Hos-0267Homo sapiens58.672e-149 441
LLPS-Loa-2443Loxodonta africana58.672e-149 441
LLPS-Man-3185Macaca nemestrina58.672e-149 441
LLPS-Dos-0711Dothistroma septosporum58.586e-150 442
LLPS-Ora-0965Ornithorhynchus anatinus58.45e-149 436
LLPS-Cas-3492Carlito syrichta58.45e-148 442
LLPS-Tag-2976Taeniopygia guttata58.43e-148 438
LLPS-Yal-0788Yarrowia lipolytica58.354e-156 458
LLPS-Orb-0524Oryza barthii58.182e-152 449
LLPS-Tut-0263Tursiops truncatus58.136e-143 424
LLPS-Mod-0935Monodelphis domestica58.132e-148 439
LLPS-Asg-0220Ashbya gossypii58.059e-141 414
LLPS-Asfu-0160Aspergillus fumigatus58.041e-152 450
LLPS-Anp-1036Anas platyrhynchos57.964e-149 439
LLPS-Leo-2764Lepisosteus oculatus57.943e-146 434
LLPS-Xim-2080Xiphophorus maculatus57.871e-149 442
LLPS-Icp-1096Ictalurus punctatus57.871e-148 439
LLPS-Phn-0291Phaeosphaeria nodorum57.821e-139 414
LLPS-Sac-1569Saccharomyces cerevisiae57.492e-142 421
LLPS-Cis-1734Ciona savignyi57.412e-148 438
LLPS-Ran-1984Rattus norvegicus57.12e-139 416
LLPS-Sem-1152Selaginella moellendorffii56.954e-147 432
LLPS-Pytr-0486Pyrenophora triticirepentis56.913e-149 440
LLPS-Map-0081Magnaporthe poae56.772e-144 428
LLPS-Zyt-0428Zymoseptoria tritici56.747e-149 439
LLPS-Pyt-0677Pyrenophora teres56.652e-148 438
LLPS-Cym-0742Cyanidioschyzon merolae56.634e-144 427
LLPS-Pof-0892Poecilia formosa56.362e-146 434
LLPS-Cii-2283Ciona intestinalis56.354e-150 443
LLPS-Blg-1368Blumeria graminis56.322e-143 424
LLPS-Orm-1742Oryza meridionalis56.255e-137 412
LLPS-Lac-0393Latimeria chalumnae55.384e-142 423
LLPS-Zem-0961Zea mays55.312e-149 441
LLPS-Tum-0089Tuber melanosporum54.742e-136 405
LLPS-Chc-1100Chondrus crispus54.386e-139 414
LLPS-Cae-0841Caenorhabditis elegans54.223e-131 394
LLPS-Amt-1869Amborella trichopoda54.12e-130 391
LLPS-Otg-1174Otolemur garnettii53.329e-125 378
LLPS-Osl-0653Ostreococcus lucimarinus52.833e-129 387
LLPS-Aso-0738Aspergillus oryzae52.348e-132 396
LLPS-Rhb-0061Rhinopithecus bieti51.24e-112 345
LLPS-Mea-4266Mesocricetus auratus48.462e-32 125