• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dac-1645
DCAR_005465

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase 2
Gene Name: DCAR_005465
Ensembl Gene: DCAR_005465
Ensembl Protein: KZN04628
Organism: Daucus carota
Taxa ID: 79200
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblKZN04628KZN04628
UniProtA0A166D1Q5, A0A166D1Q5_DAUCS
GeneBankLNRQ01000002KZN04628.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MFRMIDTESA  KKKKKKSKSK  KKKQPPQQTD  PPTIPVSELF  PSGEFPEGEI  QQYKDDNLWR  60
61    TTSEEKRELE  RLEKPIYDSV  RQAAEVHRQV  RKYMKGIIKP  GMPMTELCET  LENTVRKLIS  120
121   ENGLEAGIAF  PTGCSLNWVA  AHWTPNSGDT  TVLQYDDVMK  LDFGTHINGR  IVDCAFTVAF  180
181   NPMFNPLLEA  SREATNTGIK  ESGIDVRLCD  VGAAIQEVME  SYEVEINGKV  FQVKSIRNLN  240
241   GHSIGPYQIH  AGKSVPIVKG  GEQTKMEEGE  FYAIETFGST  GKGYVREDLE  CSHYMKNFDV  300
301   GHMPLRLPRA  KQLLATINKN  FSTLAFCRRY  LDRLGETKYL  MALKNLCDAG  IVQTYPPLCD  360
361   VKGSYVSQFE  HTILLRPTCK  EVVSRGDDY  389
Nucleotide CDS Sequence (FASTA)
1     ATGTTTCGAA  TGATTGATAC  AGAATCTGCA  AAAAAGAAGA  AGAAGAAAAG  TAAAAGCAAA  60
61    AAGAAAAAGC  AACCGCCACA  GCAAACTGAT  CCACCAACTA  TTCCTGTTTC  AGAACTTTTT  120
121   CCTTCCGGAG  AGTTTCCAGA  AGGAGAAATT  CAACAATACA  AAGATGATAA  TCTATGGAGG  180
181   ACCACTTCAG  AGGAAAAGAG  GGAGTTAGAG  CGTCTAGAAA  AACCCATATA  TGATTCAGTA  240
241   CGTCAAGCAG  CAGAAGTTCA  TCGTCAGGTG  CGGAAATATA  TGAAGGGTAT  TATAAAGCCT  300
301   GGAATGCCAA  TGACTGAGCT  ATGTGAGACC  TTAGAAAACA  CTGTTCGCAA  GTTAATATCA  360
361   GAGAATGGAT  TAGAAGCAGG  CATTGCATTT  CCTACAGGAT  GCTCATTGAA  CTGGGTTGCT  420
421   GCCCACTGGA  CCCCAAATTC  TGGAGATACC  ACTGTATTGC  AGTATGATGA  TGTGATGAAA  480
481   TTGGATTTTG  GAACTCATAT  TAATGGACGT  ATAGTTGACT  GTGCATTTAC  CGTGGCATTC  540
541   AATCCAATGT  TTAATCCATT  GCTTGAGGCC  TCACGGGAAG  CCACAAATAC  TGGGATCAAG  600
601   GAATCAGGGA  TCGATGTTCG  TCTTTGTGAT  GTTGGTGCTG  CAATCCAAGA  GGTCATGGAA  660
661   TCGTATGAAG  TAGAGATCAA  TGGAAAGGTG  TTTCAAGTTA  AGAGTATCCG  GAATTTGAAT  720
721   GGCCATAGCA  TTGGGCCTTA  CCAAATTCAT  GCTGGGAAGT  CGGTTCCAAT  CGTGAAAGGT  780
781   GGTGAACAGA  CGAAAATGGA  AGAGGGTGAA  TTCTATGCTA  TTGAAACTTT  TGGATCCACA  840
841   GGCAAGGGCT  ATGTCAGGGA  GGATTTGGAG  TGCAGCCATT  ATATGAAGAA  TTTTGATGTC  900
901   GGGCACATGC  CGTTACGTTT  GCCAAGAGCA  AAACAACTTC  TTGCGACAAT  CAATAAGAAT  960
961   TTCTCCACAT  TGGCATTCTG  TAGGCGTTAT  TTAGACCGTC  TTGGAGAGAC  CAAATATCTA  1020
1021  ATGGCGCTGA  AGAATTTGTG  TGATGCTGGT  ATTGTTCAGA  CATATCCACC  TCTTTGTGAT  1080
1081  GTTAAAGGAA  GCTATGTGTC  TCAGTTTGAG  CACACAATCT  TACTTCGGCC  AACTTGCAAA  1140
1141  GAGGTTGTAT  CCAGAGGCGA  TGACTACTGA  1170

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Cytoplasm
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Via-1916Vigna angularis95.162e-82 254
LLPS-Mae-0126Manihot esculenta94.350.0 683
LLPS-Viv-1516Vitis vinifera94.070.0 681
LLPS-Sot-1511Solanum tuberosum93.50.0 677
LLPS-Thc-1568Theobroma cacao93.50.0 674
LLPS-Met-0403Medicago truncatula93.220.0 678
LLPS-Sol-1543Solanum lycopersicum93.220.0 672
LLPS-Nia-2348Nicotiana attenuata93.220.0 678
LLPS-Pot-1287Populus trichocarpa92.940.0 678
LLPS-Hea-0020Helianthus annuus92.370.0 679
LLPS-Coc-1079Corchorus capsularis92.370.0 672
LLPS-Phv-1458Phaseolus vulgaris92.090.0 677
LLPS-Cus-1888Cucumis sativus91.810.0 670
LLPS-Arl-1907Arabidopsis lyrata91.810.0 672
LLPS-Vir-0061Vigna radiata91.810.0 675
LLPS-Prp-0776Prunus persica91.810.0 670
LLPS-Gor-0754Gossypium raimondii91.810.0 677
LLPS-Art-0404Arabidopsis thaliana91.810.0 675
LLPS-Mua-1192Musa acuminata91.240.0 676
LLPS-Glm-0306Glycine max91.240.0 672
LLPS-Brn-2613Brassica napus90.960.0 666
LLPS-Bro-1313Brassica oleracea90.960.0 667
LLPS-Brr-3062Brassica rapa90.620.0 667
LLPS-Sei-0480Setaria italica90.110.0 662
LLPS-Tra-0129Triticum aestivum89.270.0 662
LLPS-Hov-0316Hordeum vulgare89.270.0 658
LLPS-Sem-1152Selaginella moellendorffii89.270.0 655
LLPS-Tru-1611Triticum urartu89.270.0 659
LLPS-Brd-2039Brachypodium distachyon88.70.0 659
LLPS-Sob-0293Sorghum bicolor88.70.0 654
LLPS-Orp-0913Oryza punctata88.420.0 657
LLPS-Ori-1165Oryza indica88.140.0 655
LLPS-Org-0576Oryza glaberrima88.140.0 655
LLPS-Orbr-0781Oryza brachyantha88.140.0 654
LLPS-Orr-1416Oryza rufipogon87.850.0 653
LLPS-Ors-0164Oryza sativa87.850.0 653
LLPS-Orgl-2117Oryza glumaepatula86.720.0 637
LLPS-Lep-2275Leersia perrieri86.720.0 638
LLPS-Orni-0338Oryza nivara86.720.0 637
LLPS-Php-1829Physcomitrella patens86.160.0 642
LLPS-Amt-1869Amborella trichopoda85.940.0 566
LLPS-Orb-0524Oryza barthii85.050.0 649
LLPS-Orm-1742Oryza meridionalis83.480.0 596
LLPS-Zem-0961Zea mays82.220.0 645
LLPS-Pes-1896Pelodiscus sinensis79.453e-176 500
LLPS-Chr-0401Chlamydomonas reinhardtii76.840.0 570
LLPS-Mam-3627Macaca mulatta76.130.0 535
LLPS-Nol-1806Nomascus leucogenys75.830.0 534
LLPS-Xet-3470Xenopus tropicalis74.370.0 555
LLPS-Anc-3235Anolis carolinensis72.980.0 549
LLPS-Fia-1306Ficedula albicollis72.980.0 545
LLPS-Gas-0008Galdieria sulphuraria72.880.0 537
LLPS-Sah-0877Sarcophilus harrisii72.70.0 545
LLPS-Gaga-1057Gallus gallus72.70.0 542
LLPS-Cap-0800Cavia porcellus72.70.0 548
LLPS-Meg-1216Meleagris gallopavo72.50.0 538
LLPS-Anp-1036Anas platyrhynchos72.50.0 540
LLPS-Mup-2168Mustela putorius furo72.420.0 546
LLPS-Aim-1965Ailuropoda melanoleuca72.420.0 546
LLPS-Ova-0459Ovis aries72.420.0 546
LLPS-Myl-1479Myotis lucifugus72.420.0 546
LLPS-Bot-3755Bos taurus72.420.0 546
LLPS-Fud-0843Fukomys damarensis72.420.0 547
LLPS-Mum-3099Mus musculus72.420.0 545
LLPS-Sus-2648Sus scrofa72.420.0 546
LLPS-Tag-2976Taeniopygia guttata72.420.0 543
LLPS-Ict-3096Ictidomys tridecemlineatus72.420.0 548
LLPS-Eqc-3814Equus caballus72.420.0 546
LLPS-Caf-3192Canis familiaris72.420.0 547
LLPS-Orc-2119Oryctolagus cuniculus72.420.0 547
LLPS-Fec-2275Felis catus72.420.0 546
LLPS-Urm-2624Ursus maritimus72.420.0 546
LLPS-Paa-1906Papio anubis72.140.0 543
LLPS-Mal-0914Mandrillus leucophaeus72.140.0 543
LLPS-Dio-0527Dipodomys ordii72.140.0 544
LLPS-Gaa-0732Gasterosteus aculeatus72.140.0 541
LLPS-Gog-4136Gorilla gorilla72.140.0 543
LLPS-Caj-2622Callithrix jacchus72.140.0 543
LLPS-Chs-4138Chlorocebus sabaeus72.140.0 543
LLPS-Maf-1964Macaca fascicularis72.140.0 543
LLPS-Cea-1023Cercocebus atys72.140.0 543
LLPS-Aon-2125Aotus nancymaae72.140.0 543
LLPS-Poa-0781Pongo abelii72.140.0 543
LLPS-Pat-0957Pan troglodytes72.140.0 544
LLPS-Pap-2478Pan paniscus72.140.0 544
LLPS-Hos-0267Homo sapiens72.140.0 544
LLPS-Loa-2443Loxodonta africana72.140.0 543
LLPS-Man-3185Macaca nemestrina72.140.0 543
LLPS-Tar-3299Takifugu rubripes71.870.0 541
LLPS-Ora-0965Ornithorhynchus anatinus71.870.0 540
LLPS-Cas-3492Carlito syrichta71.870.0 544
LLPS-Orn-2497Oreochromis niloticus71.870.0 540
LLPS-Scm-1244Scophthalmus maximus71.870.0 545
LLPS-Mod-0935Monodelphis domestica71.870.0 543
LLPS-Scf-0970Scleropages formosus71.590.0 534
LLPS-Orl-2629Oryzias latipes71.590.0 543
LLPS-Icp-1096Ictalurus punctatus71.310.0 538
LLPS-Tut-0263Tursiops truncatus71.030.0 522
LLPS-Leo-2764Lepisosteus oculatus70.990.0 523
LLPS-Xim-2080Xiphophorus maculatus70.750.0 535
LLPS-Asm-1574Astyanax mexicanus70.750.0 531
LLPS-Ten-2503Tetraodon nigroviridis70.750.0 531
LLPS-Dar-2650Danio rerio70.750.0 530
LLPS-Ran-1984Rattus norvegicus70.293e-179 515
LLPS-Chc-1100Chondrus crispus69.663e-180 516
LLPS-Cii-2283Ciona intestinalis69.530.0 531
LLPS-Osl-0653Ostreococcus lucimarinus69.36e-178 509
LLPS-Cis-1734Ciona savignyi69.250.0 529
LLPS-Drm-1540Drosophila melanogaster69.060.0 527
LLPS-Pof-0892Poecilia formosa68.830.0 524
LLPS-Lac-0393Latimeria chalumnae68.720.0 528
LLPS-Cae-0841Caenorhabditis elegans66.394e-169 489
LLPS-Cym-0742Cyanidioschyzon merolae66.14e-171 494
LLPS-Abg-0767Absidia glauca65.929e-175 501
LLPS-Otg-2950Otolemur garnettii65.843e-169 489
LLPS-Scp-0507Schizosaccharomyces pombe65.824e-171 492
LLPS-Put-0170Puccinia triticina65.023e-110 336
LLPS-Nef-0018Neosartorya fischeri64.725e-164 475
LLPS-Scj-0669Schizosaccharomyces japonicus64.413e-168 484
LLPS-Asf-0832Aspergillus flavus64.172e-163 474
LLPS-Asni-0120Aspergillus niger63.892e-162 470
LLPS-Ast-0814Aspergillus terreus63.892e-163 473
LLPS-Scc-0617Schizosaccharomyces cryophilus63.565e-164 474
LLPS-Asc-0394Aspergillus clavatus62.573e-149 437
LLPS-Nec-0478Neurospora crassa62.52e-157 457
LLPS-Lem-1112Leptosphaeria maculans62.51e-160 467
LLPS-Zyt-0428Zymoseptoria tritici62.263e-155 453
LLPS-Asn-0391Aspergillus nidulans62.262e-159 463
LLPS-Dos-0711Dothistroma septosporum62.262e-157 459
LLPS-Phn-0291Phaeosphaeria nodorum61.44e-146 429
LLPS-Miv-1309Microbotryum violaceum61.26e-153 447
LLPS-Pyt-0677Pyrenophora teres61.112e-157 458
LLPS-Pytr-0486Pyrenophora triticirepentis61.116e-157 457
LLPS-Trr-1246Trichoderma reesei61.112e-155 449
LLPS-Rhb-0061Rhinopithecus bieti61.01e-144 426
LLPS-Asfu-0160Aspergillus fumigatus60.991e-157 460
LLPS-Asg-0220Ashbya gossypii60.875e-136 400
LLPS-Cog-0564Colletotrichum gloeosporioides60.831e-150 441
LLPS-Blg-1368Blumeria graminis60.662e-150 440
LLPS-Pug-0627Puccinia graminis60.52e-155 453
LLPS-Ved-0285Verticillium dahliae60.284e-148 434
LLPS-Trv-0635Trichoderma virens60.286e-153 446
LLPS-Cogr-0752Colletotrichum graminicola60.05e-150 439
LLPS-Fus-0810Fusarium solani60.06e-154 449
LLPS-Beb-1007Beauveria bassiana60.04e-151 441
LLPS-Fuv-0788Fusarium verticillioides59.721e-151 443
LLPS-Fuo-0163Fusarium oxysporum59.721e-151 443
LLPS-Kop-0038Komagataella pastoris59.668e-150 439
LLPS-Mel-0742Melampsora laricipopulina59.392e-147 432
LLPS-Gag-0741Gaeumannomyces graminis59.171e-149 438
LLPS-Coo-1266Colletotrichum orbiculare58.898e-148 433
LLPS-Mao-1254Magnaporthe oryzae58.615e-150 439
LLPS-Tum-0089Tuber melanosporum58.062e-141 416
LLPS-Crn-0326Cryptococcus neoformans58.024e-140 414
LLPS-Map-0081Magnaporthe poae57.929e-144 423
LLPS-Sac-1569Saccharomyces cerevisiae57.896e-139 410
LLPS-Yal-0788Yarrowia lipolytica56.961e-148 437
LLPS-Usm-0536Ustilago maydis56.516e-141 413
LLPS-Mea-4266Mesocricetus auratus54.782e-30 119
LLPS-Spr-0684Sporisorium reilianum54.679e-138 409
LLPS-Aso-0738Aspergillus oryzae52.044e-122 369