• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gag-0741
20341112

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase 2
Gene Name: 20341112, GGTG_00654
Ensembl Gene: GGTG_00654
Ensembl Protein: EJT80660
Organism: Gaeumannomyces graminis
Taxa ID: 644352
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEJT80660EJT80660
UniProtJ3NHB7, J3NHB7_GAGT3
GeneBankGL385395EJT80660.1
RefSeqXM_009218405.1XP_009216669.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MADQAPAEEL  AKLQVKDAAK  SNGEAAPSKP  PANGEENDSD  GSDDDGEGDD  AGAAAPAAGA  60
61    AKKKKRKPRK  KKKKGASAQT  EPPRVPISQL  FAGKEYPKGE  EVEYVNENRY  RTTSEEKRHL  120
121   DNLNSELLSD  YRQGAEAHRQ  ARKWAQKSIK  PGQSLTEIAN  NVEDAVRALV  GHQGLDEGDA  180
181   MVAGMGFPTG  LSINNCAAHY  TPNAGNKMVL  QQDDVLKVDI  GVHVGGRIVD  SAFTLAWNPR  240
241   YDQLLAAVKD  ATNTGVREAG  IDARLGEIGE  AIQETMESYE  VEIDGETFPV  KSIRNLNGHT  300
301   IERFSIHGGK  SVPIVKTADQ  TKMEEGEIYA  IETFGSTGNG  YVRDEGEVSH  YAKRADAPNV  360
361   ALRLTSAKNV  LNIINKNFGT  LPFCRRYIDR  LGQDKYLLGL  NNLVSNGIVE  AYPPLVDKKG  420
421   SYTAQYEHTI  LLRPTVKEVI  SRGDDY  446
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGACC  AAGCACCAGC  TGAAGAGCTG  GCAAAGCTCC  AGGTCAAGGA  CGCAGCCAAG  60
61    AGCAACGGCG  AGGCCGCGCC  AAGCAAACCG  CCCGCCAACG  GAGAGGAGAA  CGACAGCGAC  120
121   GGTTCCGACG  ATGACGGGGA  GGGCGACGAT  GCCGGCGCCG  CCGCGCCCGC  CGCAGGAGCG  180
181   GCCAAGAAGA  AGAAGAGAAA  GCCGCGCAAG  AAGAAGAAGA  AGGGCGCGTC  GGCCCAGACG  240
241   GAGCCGCCAA  GGGTCCCCAT  CTCGCAGCTG  TTCGCCGGCA  AGGAGTACCC  CAAGGGCGAG  300
301   GAGGTGGAGT  ACGTGAACGA  GAACCGGTAC  CGCACCACGA  GCGAGGAGAA  GCGGCACCTG  360
361   GACAACCTCA  ACAGCGAGCT  GCTCAGCGAC  TACCGGCAGG  GGGCCGAGGC  GCACCGGCAA  420
421   GCGCGCAAGT  GGGCGCAGAA  GAGCATCAAG  CCCGGGCAGT  CGCTGACCGA  GATCGCCAAC  480
481   AACGTCGAGG  ACGCGGTCCG  GGCGCTGGTC  GGGCACCAGG  GGCTCGACGA  GGGCGACGCC  540
541   ATGGTGGCGG  GCATGGGCTT  CCCGACGGGG  CTGAGCATCA  ACAACTGCGC  GGCGCACTAC  600
601   ACGCCCAACG  CGGGCAACAA  GATGGTGCTG  CAGCAGGACG  ACGTACTCAA  GGTGGACATT  660
661   GGCGTGCACG  TGGGCGGGCG  CATCGTCGAC  AGCGCCTTCA  CGCTGGCCTG  GAACCCGCGC  720
721   TACGACCAAC  TGCTGGCGGC  CGTCAAGGAC  GCGACCAACA  CGGGCGTGCG  CGAGGCGGGC  780
781   ATCGACGCGC  GGCTGGGCGA  GATCGGCGAG  GCCATTCAGG  AGACGATGGA  GAGCTACGAG  840
841   GTCGAGATCG  ACGGCGAGAC  CTTCCCCGTC  AAGTCGATCC  GGAACCTCAA  CGGCCACACC  900
901   ATCGAGCGCT  TCAGCATCCA  CGGCGGCAAG  AGCGTGCCCA  TCGTCAAGAC  GGCCGACCAG  960
961   ACCAAGATGG  AGGAGGGCGA  GATCTACGCC  ATCGAGACCT  TTGGCAGCAC  CGGCAACGGC  1020
1021  TACGTGCGCG  ACGAGGGCGA  GGTTTCGCAC  TATGCCAAGC  GCGCCGATGC  GCCCAACGTC  1080
1081  GCCCTGCGCC  TGACCTCGGC  TAAGAACGTG  CTGAACATCA  TCAACAAGAA  CTTTGGGACG  1140
1141  CTGCCCTTCT  GCCGTCGCTA  CATTGACCGC  TTAGGCCAGG  ACAAGTACCT  TCTCGGTCTC  1200
1201  AACAACCTTG  TCTCGAACGG  TATTGTTGAG  GCATACCCGC  CACTCGTAGA  CAAGAAGGGT  1260
1261  TCCTACACGG  CCCAATATGA  GCATACCATT  CTCCTCAGGC  CAACGGTCAA  GGAGGTTATC  1320
1321  AGCCGGGGAG  ACGACTATTA  A  1341

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Cytoplasm
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Map-0081Magnaporthe poae93.580.0 766
LLPS-Mao-1254Magnaporthe oryzae86.960.0 684
LLPS-Nec-0478Neurospora crassa80.160.0 634
LLPS-Trv-0635Trichoderma virens77.990.0 618
LLPS-Trr-1246Trichoderma reesei77.780.0 600
LLPS-Beb-1007Beauveria bassiana77.170.0 607
LLPS-Fus-0810Fusarium solani76.90.0 614
LLPS-Cogr-0752Colletotrichum graminicola76.360.0 600
LLPS-Fuo-0163Fusarium oxysporum75.540.0 606
LLPS-Fuv-0788Fusarium verticillioides75.540.0 606
LLPS-Cog-0564Colletotrichum gloeosporioides75.270.0 590
LLPS-Ast-0814Aspergillus terreus75.270.0 591
LLPS-Coo-1266Colletotrichum orbiculare74.730.0 588
LLPS-Asni-0120Aspergillus niger74.730.0 590
LLPS-Asf-0832Aspergillus flavus74.460.0 588
LLPS-Nef-0018Neosartorya fischeri73.910.0 588
LLPS-Asn-0391Aspergillus nidulans73.050.0 584
LLPS-Asc-0394Aspergillus clavatus72.360.0 551
LLPS-Pytr-0486Pyrenophora triticirepentis72.010.0 570
LLPS-Blg-1368Blumeria graminis71.820.0 574
LLPS-Phn-0291Phaeosphaeria nodorum71.790.0 553
LLPS-Pyt-0677Pyrenophora teres71.740.0 569
LLPS-Dos-0711Dothistroma septosporum71.430.0 561
LLPS-Ved-0285Verticillium dahliae71.30.0 617
LLPS-Lem-1112Leptosphaeria maculans71.20.0 562
LLPS-Zyt-0428Zymoseptoria tritici71.160.0 563
LLPS-Tum-0089Tuber melanosporum70.650.0 553
LLPS-Asfu-0160Aspergillus fumigatus70.260.0 576
LLPS-Scj-0669Schizosaccharomyces japonicus68.210.0 526
LLPS-Put-0170Puccinia triticina67.081e-108 334
LLPS-Via-1916Vigna angularis66.946e-53 180
LLPS-Scc-0617Schizosaccharomyces cryophilus64.671e-173 501
LLPS-Pes-1896Pelodiscus sinensis64.092e-140 411
LLPS-Scp-0507Schizosaccharomyces pombe63.323e-169 490
LLPS-Kop-0038Komagataella pastoris63.192e-162 473
LLPS-Mam-3627Macaca mulatta62.021e-155 456
LLPS-Nol-1806Nomascus leucogenys61.724e-155 454
LLPS-Pug-0627Puccinia graminis61.71e-163 476
LLPS-Anc-3235Anolis carolinensis60.864e-165 484
LLPS-Spr-0684Sporisorium reilianum60.852e-152 449
LLPS-Usm-0536Ustilago maydis60.762e-149 437
LLPS-Anp-1036Anas platyrhynchos60.438e-165 479
LLPS-Xet-3470Xenopus tropicalis60.322e-165 482
LLPS-Cap-0800Cavia porcellus60.324e-164 479
LLPS-Orn-0809Oreochromis niloticus60.323e-163 476
LLPS-Fia-1306Ficedula albicollis60.327e-166 481
LLPS-Tag-2976Taeniopygia guttata60.058e-164 478
LLPS-Ict-3096Ictidomys tridecemlineatus60.054e-164 479
LLPS-Gaga-1057Gallus gallus60.051e-163 477
LLPS-Eqc-3814Equus caballus60.056e-164 478
LLPS-Caf-3192Canis familiaris60.057e-164 478
LLPS-Poa-0781Pongo abelii60.052e-164 479
LLPS-Sob-0293Sorghum bicolor60.052e-161 471
LLPS-Man-3185Macaca nemestrina60.051e-164 480
LLPS-Brr-3062Brassica rapa60.055e-161 469
LLPS-Fec-2275Felis catus60.055e-164 478
LLPS-Hos-0267Homo sapiens60.059e-165 480
LLPS-Urm-2624Ursus maritimus60.055e-164 478
LLPS-Pap-2478Pan paniscus60.051e-164 480
LLPS-Pat-0957Pan troglodytes60.051e-164 480
LLPS-Ova-0459Ovis aries60.056e-164 478
LLPS-Myl-1479Myotis lucifugus60.053e-164 479
LLPS-Mup-2168Mustela putorius furo60.055e-164 478
LLPS-Aim-1965Ailuropoda melanoleuca60.055e-164 478
LLPS-Mal-0914Mandrillus leucophaeus60.051e-164 480
LLPS-Paa-1906Papio anubis60.051e-164 480
LLPS-Sei-0480Setaria italica60.051e-160 469
LLPS-Bot-3755Bos taurus60.054e-164 479
LLPS-Xim-2080Xiphophorus maculatus60.052e-163 477
LLPS-Caj-2622Callithrix jacchus60.052e-164 479
LLPS-Fud-0843Fukomys damarensis60.058e-164 478
LLPS-Gog-4136Gorilla gorilla60.058e-165 480
LLPS-Sus-2648Sus scrofa60.056e-164 478
LLPS-Cea-1023Cercocebus atys60.051e-164 480
LLPS-Sah-0877Sarcophilus harrisii60.059e-166 480
LLPS-Aon-2125Aotus nancymaae60.052e-164 479
LLPS-Brn-2492Brassica napus60.051e-161 471
LLPS-Ora-0965Ornithorhynchus anatinus60.052e-166 481
LLPS-Chs-4138Chlorocebus sabaeus60.055e-165 480
LLPS-Mum-3099Mus musculus60.058e-164 478
LLPS-Maf-1964Macaca fascicularis60.051e-164 480
LLPS-Meg-1216Meleagris gallopavo59.894e-163 474
LLPS-Abg-0767Absidia glauca59.891e-158 463
LLPS-Cas-3492Carlito syrichta59.799e-163 480
LLPS-Orc-2119Oryctolagus cuniculus59.798e-164 478
LLPS-Loa-2443Loxodonta africana59.794e-163 476
LLPS-Dio-0527Dipodomys ordii59.792e-163 477
LLPS-Bro-1313Brassica oleracea59.784e-161 469
LLPS-Arl-1907Arabidopsis lyrata59.781e-154 453
LLPS-Sac-1569Saccharomyces cerevisiae59.623e-145 428
LLPS-Mod-0935Monodelphis domestica59.521e-162 475
LLPS-Orl-2629Oryzias latipes59.525e-164 478
LLPS-Sem-1152Selaginella moellendorffii59.513e-152 444
LLPS-Scm-1244Scophthalmus maximus59.252e-157 474
LLPS-Scf-0970Scleropages formosus59.255e-163 476
LLPS-Gaa-0732Gasterosteus aculeatus59.252e-161 469
LLPS-Gas-0008Galdieria sulphuraria59.242e-153 449
LLPS-Dac-1645Daucus carota59.241e-154 451
LLPS-Sol-1543Solanum lycopersicum59.245e-154 449
LLPS-Miv-1309Microbotryum violaceum59.212e-159 466
LLPS-Cii-2283Ciona intestinalis59.23e-162 474
LLPS-Tar-0070Takifugu rubripes58.981e-161 471
LLPS-Tut-0263Tursiops truncatus58.984e-155 456
LLPS-Mae-0126Manihot esculenta58.972e-153 449
LLPS-Art-0404Arabidopsis thaliana58.977e-159 464
LLPS-Gor-0754Gossypium raimondii58.971e-157 460
LLPS-Mel-0742Melampsora laricipopulina58.781e-151 446
LLPS-Ten-2503Tetraodon nigroviridis58.715e-160 468
LLPS-Dar-3061Danio rerio58.711e-162 475
LLPS-Org-0576Oryza glaberrima58.77e-157 459
LLPS-Coc-1079Corchorus capsularis58.77e-152 446
LLPS-Orr-1416Oryza rufipogon58.75e-157 459
LLPS-Nia-2348Nicotiana attenuata58.71e-151 445
LLPS-Phv-1458Phaseolus vulgaris58.77e-157 458
LLPS-Orbr-0781Oryza brachyantha58.73e-154 457
LLPS-Orp-0913Oryza punctata58.75e-157 459
LLPS-Ors-0164Oryza sativa58.78e-157 459
LLPS-Vir-0061Vigna radiata58.78e-157 460
LLPS-Hov-0316Hordeum vulgare58.71e-158 464
LLPS-Thc-1568Theobroma cacao58.72e-150 445
LLPS-Ori-1165Oryza indica58.77e-157 459
LLPS-Cis-1734Ciona savignyi58.678e-162 472
LLPS-Pof-0892Poecilia formosa58.496e-159 466
LLPS-Hea-0020Helianthus annuus58.472e-156 458
LLPS-Asm-1574Astyanax mexicanus58.453e-160 471
LLPS-Tru-1611Triticum urartu58.423e-158 462
LLPS-Pot-1287Populus trichocarpa58.426e-158 461
LLPS-Tra-0129Triticum aestivum58.421e-157 461
LLPS-Chr-0401Chlamydomonas reinhardtii58.422e-154 455
LLPS-Sot-1511Solanum tuberosum58.423e-152 447
LLPS-Glm-0306Glycine max58.421e-156 458
LLPS-Lac-0393Latimeria chalumnae58.255e-161 471
LLPS-Ran-1984Rattus norvegicus58.242e-153 451
LLPS-Leo-2764Lepisosteus oculatus58.246e-158 463
LLPS-Brd-2039Brachypodium distachyon58.156e-158 462
LLPS-Cus-1888Cucumis sativus58.154e-151 443
LLPS-Orgl-2117Oryza glumaepatula58.152e-153 450
LLPS-Orni-0338Oryza nivara58.152e-153 450
LLPS-Drm-1540Drosophila melanogaster57.981e-159 466
LLPS-Viv-1516Vitis vinifera57.888e-152 445
LLPS-Met-0403Medicago truncatula57.885e-155 453
LLPS-Aso-0738Aspergillus oryzae57.873e-154 453
LLPS-Crn-0326Cryptococcus neoformans57.816e-149 439
LLPS-Asg-0220Ashbya gossypii57.735e-135 400
LLPS-Mua-1192Musa acuminata57.616e-155 454
LLPS-Php-1829Physcomitrella patens57.617e-156 457
LLPS-Lep-2275Leersia perrieri57.341e-150 443
LLPS-Yal-0788Yarrowia lipolytica56.861e-159 467
LLPS-Orb-0524Oryza barthii56.812e-153 451
LLPS-Icp-1096Ictalurus punctatus56.579e-157 459
LLPS-Prp-0776Prunus persica56.523e-152 447
LLPS-Orm-1742Oryza meridionalis55.896e-142 424
LLPS-Zem-0961Zea mays54.989e-156 457
LLPS-Otg-1174Otolemur garnettii54.964e-143 425
LLPS-Chc-1100Chondrus crispus54.891e-147 436
LLPS-Amt-1869Amborella trichopoda54.791e-129 389
LLPS-Cym-0742Cyanidioschyzon merolae54.171e-140 419
LLPS-Cae-0841Caenorhabditis elegans53.64e-142 422
LLPS-Osl-0653Ostreococcus lucimarinus53.391e-132 396
LLPS-Rhb-0061Rhinopithecus bieti50.45e-123 373
LLPS-Mea-4266Mesocricetus auratus48.843e-34 130