Mus musculus      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 110 genes.  Reviewed (95 or Unreviewed (15

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mum-0785
ENSMUSG00000027719.15
Q5SUE7
Adad1
2
LLPS-Mum-2028
ENSMUSG00000024266.8
Q9D5P4
Adad2
3
LLPS-Mum-3526
ENSMUSG00000036698.11
Q8CJG0
Ago2
4
LLPS-Mum-2271
ENSMUSG00000050089.13
Q60662
Akap4
5
LLPS-Mum-2562
ENSMUSG00000010796.11
Q8VD46
Asz1
6
LLPS-Mum-1640
ENSMUSG00000078676.9
Q8K3W3
Casc3
7
LLPS-Mum-2377
ENSMUSG00000018509.8
Q9CXS4
Cenpv
8
LLPS-Mum-2165
ENSMUSG00000030057.15
P53996
Cnbp
9
LLPS-Mum-3011
ENSMUSG00000039224.1
P16381
D1Pas1
10
LLPS-Mum-1905
ENSMUSG00000021962.9
Q91YD3
Dcp1a
11
LLPS-Mum-2171
ENSMUSG00000037149.10
Q91VR5
Ddx1
12
LLPS-Mum-1386
ENSMUSG00000032101.6
Q9QY15
Ddx25
13
LLPS-Mum-1835
ENSMUSG00000021758.14
Q61496
Ddx4
14
LLPS-Mum-1264
ENSMUSG00000020719.14
Q61656
Ddx5
15
LLPS-Mum-1752
ENSMUSG00000042699.11
O70133
Dhx9
16
LLPS-Mum-1100
ENSMUSG00000036270.16
Q3UJB9
Edc4
17
LLPS-Mum-0218
ENSMUSG00000037742.14
P10126
Eef1a1
18
LLPS-Mum-0425
ENSMUSG00000059796.16
P60843
Eif4a1
19
LLPS-Mum-0303
ENSMUSG00000025580.15
Q91VC3
Eif4a3
20
LLPS-Mum-1951
ENSMUSG00000028156.12
P63073
Eif4e
21
LLPS-Mum-2599
ENSMUSG00000040028.10
P70372
Elavl1
22
LLPS-Mum-2279
ENSMUSG00000009079.16
Q61545
Ewsr1
23
LLPS-Mum-2970
ENSMUSG00000027528.12
O08716
Fabp9
24
LLPS-Mum-2887
ENSMUSG00000025241.16
Q8VDC1
Fyco1
25
LLPS-Mum-3191
ENSMUSG00000075706.10
O70325
Gpx4
26
LLPS-Mum-3020
ENSMUSG00000061991.2
Q8CGP5
Hist1h2af
27
LLPS-Mum-0749
ENSMUSG00000069265.2
P68433
Hist1h3i
28
LLPS-Mum-2703
ENSMUSG00000004980.16
O88569
Hnrnpa2b1
29
LLPS-Mum-1335
ENSMUSG00000059005.13
Q8BG05
Hnrnpa3
30
LLPS-Mum-0430
ENSMUSG00000029328.15
Q9Z130
Hnrnpdl
31
LLPS-Mum-1929
ENSMUSG00000042079.13
Q9Z2X1
Hnrnpf
32
LLPS-Mum-0154
ENSMUSG00000007850.16
O35737
Hnrnph1
33
LLPS-Mum-2923
ENSMUSG00000059208.15
Q9D0E1
Hnrnpm
34
LLPS-Mum-1798
ENSMUSG00000039630.10
Q8VEK3
Hnrnpu
35
LLPS-Mum-2237
ENSMUSG00000021270.13
P07901
Hsp90aa1
36
LLPS-Mum-2034
ENSMUSG00000023944.14
P11499
Hsp90ab1
37
LLPS-Mum-1932
ENSMUSG00000059970.7
P17156
Hspa2
38
LLPS-Mum-2168
ENSMUSG00000029814.10
Q9CPN8
Igf2bp3
39
LLPS-Mum-2960
ENSMUSG00000032178.14
Q9Z1X4
Ilf3
40
LLPS-Mum-0913
ENSMUSG00000032594.11
Q6PD10
Ip6k1
41
LLPS-Mum-0356
ENSMUSG00000028790.13
Q60749
Khdrbs1
42
LLPS-Mum-3390
ENSMUSG00000063229.15
P06151
Ldha
43
LLPS-Mum-2857
ENSMUSG00000030851.15
P00342
Ldhc
44
LLPS-Mum-2231
ENSMUSG00000067367.9
Q08288
Lyar
45
LLPS-Mum-1519
ENSMUSG00000040629.8
Q8BVN9
Mael
46
LLPS-Mum-1614
ENSMUSG00000030188.12
Q9CQL1
Magohb
47
LLPS-Mum-1015
ENSMUSG00000026234.12
P09405
Ncl
48
LLPS-Mum-0662
ENSMUSG00000019988.7
P33215
Nedd1
49
LLPS-Mum-2569
ENSMUSG00000061923.4
Q61999
Odf1
50
LLPS-Mum-2049
ENSMUSG00000022283.15
P29341
Pabpc1
51
LLPS-Mum-0768
ENSMUSG00000051695.6
P60335
Pcbp1
52
LLPS-Mum-2207
ENSMUSG00000056851.14
Q61990
Pcbp2
53
LLPS-Mum-2658
ENSMUSG00000029423.10
Q9JMB7
Piwil1
54
LLPS-Mum-0449
ENSMUSG00000033644.5
Q8CDG1
Piwil2
55
LLPS-Mum-1986
ENSMUSG00000028484.16
Q99JF8
Psip1
56
LLPS-Mum-2726
ENSMUSG00000038546.9
P69566
Ranbp9
57
LLPS-Mum-1284
ENSMUSG00000032892.14
Q9JIB0
Rangrf
58
LLPS-Mum-0917
ENSMUSG00000006456.10
Q8C2Q3
Rbm14
59
LLPS-Mum-1548
ENSMUSG00000038374.10
Q9CWZ3
Rbm8a
60
LLPS-Mum-2632
ENSMUSG00000000365.9
Q99MV7
Rnf17
61
LLPS-Mum-1862
ENSMUSG00000059291.15
Q9CXW4
Rpl11
62
LLPS-Mum-0063
ENSMUSG00000058546.8
P62751
Rpl23a
63
LLPS-Mum-1231
ENSMUSG00000098274.7
Q8BP67
Rpl24
64
LLPS-Mum-0417
ENSMUSG00000024608.10
P62264
Rps14
65
LLPS-Mum-0627
ENSMUSG00000047675.15
P62242
Rps8
66
LLPS-Mum-1853
ENSMUSG00000030655.15
Q8BKX6
Smg1
67
LLPS-Mum-1597
ENSMUSG00000038290.15
P61406
Smg6
68
LLPS-Mum-2858
ENSMUSG00000034913.10
Q32MG2
Spert
69
LLPS-Mum-2451
ENSMUSG00000018379.17
Q6PDM2
Srsf1
70
LLPS-Mum-0859
ENSMUSG00000071172.13
P84104
Srsf3
71
LLPS-Mum-1287
ENSMUSG00000023403.14
Q99MW1
Stk31
72
LLPS-Mum-1569
ENSMUSG00000025081.13
Q99MV1
Tdrd1
73
LLPS-Mum-1610
ENSMUSG00000022019.16
Q91W18
Tdrd3
74
LLPS-Mum-1155
ENSMUSG00000060985.15
Q5VCS6
Tdrd5
75
LLPS-Mum-1370
ENSMUSG00000040140.15
P61407
Tdrd6
76
LLPS-Mum-1074
ENSMUSG00000035517.17
Q8K1H1
Tdrd7
77
LLPS-Mum-1701
ENSMUSG00000054003.13
Q14BI7
Tdrd9
78
LLPS-Mum-2801
ENSMUSG00000028845.15
Q922G7
Tekt2
79
LLPS-Mum-0493
ENSMUSG00000024175.2
Q149S1
Tekt4
80
LLPS-Mum-2651
ENSMUSG00000043050.8
P11378
Tnp2
81
LLPS-Mum-0039
ENSMUSG00000009470.17
Q8BFY9
Tnpo1
82
LLPS-Mum-1878
ENSMUSG00000018322.10
Q9CYG7
Tomm34
83
LLPS-Mum-1234
ENSMUSG00000022779.16
Q9Z321
Top3b
84
LLPS-Mum-0328
ENSMUSG00000022858.16
P62996
Tra2b
85
LLPS-Mum-2479
ENSMUSG00000009246.14
Q9JJH7
Trpm5
86
LLPS-Mum-1513
ENSMUSG00000034848.17
Q0HA38
Ttc21b
87
LLPS-Mum-2576
ENSMUSG00000067338.6
P05214
Tuba3b
88
LLPS-Mum-3351
ENSMUSG00000062380.4
Q9ERD7
Tubb3
89
LLPS-Mum-0114
ENSMUSG00000058301.8
Q9EPU0
Upf1
90
LLPS-Mum-2143
ENSMUSG00000031010.17
P70398
Usp9x
91
LLPS-Mum-0038
ENSMUSG00000026728.9
P20152
Vim
92
LLPS-Mum-2797
ENSMUSG00000020078.16
P40336
Vps26a
93
LLPS-Mum-0136
ENSMUSG00000031696.9
Q9EQH3
Vps35
94
LLPS-Mum-2738
ENSMUSG00000018554.13
Q9Z2C8
Ybx2
95
LLPS-Mum-1372
ENSMUSG00000034653.11
B2RR83
Ythdc2
96
LLPS-Mum-3128
ENSMUSG00000025083.18
Q5DTU0
Afap1l2
97
LLPS-Mum-3661
ENSMUSG00000024610.14
P04441
Cd74
98
LLPS-Mum-4940
ENSMUSG00000021939.8
P10605
Ctsb
99
LLPS-Mum-3837
ENSMUSG00000058927.5
P62897
Cycs
100
LLPS-Mum-3427
ENSMUSG00000041415.10
Q8R418
Dicer1
101
LLPS-Mum-4243
ENSMUSG00000048029.10
Q8C042
Eno4
102
LLPS-Mum-4864
ENSMUSG00000050799.3
P70696
Hist1h2ba
103
LLPS-Mum-0813
ENSMUSG00000060093.6
P62806
Hist4h4
104
LLPS-Mum-1293
ENSMUSG00000091971.3
Q61696
Hspa1a
105
LLPS-Mum-3638
ENSMUSG00000031447.7
P11438
Lamp1
106
LLPS-Mum-3502
ENSMUSG00000064351.1
P00397
Mtco1
107
LLPS-Mum-3938
ENSMUSG00000029017.13
Q9CXT8
Pmpcb
108
LLPS-Mum-3243
ENSMUSG00000021880.7
Q9D244
Rnase6
109
LLPS-Mum-3069
ENSMUSG00000052707.8
Q3UHK8
Tnrc6a
110
LLPS-Mum-3745
ENSMUSG00000025171.1
Q91WB7
Ubtd1