LLPS-Mum-3011
D1Pas1

▼ OVERVIEW

Status: Reviewed
Protein Name: Putative ATP-dependent RNA helicase Pl10
Gene Name: D1Pas1, Pl10
Ensembl Gene: ENSMUSG00000039224.1
Ensembl Protein: ENSMUSP00000035261.1
Organism: Mus musculus
Taxa ID: 10090
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateDescriptionTissue/CellPMIDs
Chromatoid body
"...The list of 88 CB proteins identified in at least three separate experiments."
Round spermatids24554440

▼ FUNCTION

Putative ATP-dependent RNA helicase. Possible role in a key step of the spermatogenic process.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSHVAEEDEL  GLDQQLAGLD  LTSRDSQSGG  STASKGRYIP  PHLRNREAAK  AFYDKDGSRW  60
61    SKDKDAYSSF  GSRSDTRAKS  SFFSDRGGSG  SRGRFDERGR  SDYESVGSRG  GRSGFGKFER  120
121   GGNSRWCDKA  DEDDWSKPLP  PSERLEQELF  SGGNTGINFE  KYDDIPVEAT  GNNCPPHIES  180
181   FSDVEMGEII  MGNIELTRYT  RPTPVQKHAI  PIIKEKRDLM  ACAQTGSGKT  AAFLLPILSQ  240
241   IYTDGPGEAL  RAMKENGKYG  RRKQYPISLV  LAPTRELAVQ  IYEEARKFSY  RSRVRPCVVY  300
301   GGADIGQQIR  DLERGCHLLV  ATPGRLVDMM  ERGKIGLDFC  KYLVLDEADR  MLDMGFEPQI  360
361   RRIVEQDTMP  PKGVRHTMMF  SATFPKEIQM  LARDFLDEYI  FLAVGRVGST  SENITQKVVW  420
421   VEEADKRSFL  LDLLNATGKD  SLILVFVETK  KGADSLEDFL  YHEGYACTSI  HGDRSQRDRE  480
481   EALHQFRSGK  SPILVATAVA  ARGLDISNVK  HVINFDLPSD  IEEYVHRIGR  TGRVGNLGLA  540
541   TSFFNERNIN  ITKDLLDLLV  EAKQEVPSWL  ENMAFEHHYK  GGSRGRSKSR  FSGGFGARDY  600
601   RQSSGASSSS  FSSGRASNSR  SGGGSHGSSR  GFGGGSYGGF  YNSDGYGGNY  SSQGVDWWGN  660
Nucleotide CDS Sequence (FASTA)
1     ATGAGTCATG  TGGCAGAGGA  AGATGAGCTC  GGGCTGGACC  AGCAGTTGGC  TGGCCTAGAC  60
61    CTGACGTCTC  GGGACAGCCA  GAGCGGGGGC  AGCACAGCCA  GCAAAGGGCG  CTACATCCCC  120
121   CCTCACCTGC  GGAACCGGGA  GGCCGCGAAG  GCGTTCTACG  ACAAAGACGG  CTCACGGTGG  180
181   AGTAAAGACA  AGGATGCCTA  CAGCAGCTTC  GGGTCCCGCA  GCGACACGAG  AGCCAAGTCC  240
241   AGTTTCTTCA  GTGACCGCGG  CGGAAGCGGC  TCCAGGGGAA  GGTTTGACGA  GCGCGGGCGG  300
301   AGTGACTACG  AGAGTGTTGG  CAGCCGGGGA  GGTAGAAGTG  GCTTTGGCAA  ATTTGAGCGG  360
361   GGCGGGAACA  GTCGCTGGTG  TGACAAAGCA  GACGAGGATG  ACTGGTCGAA  ACCGCTCCCA  420
421   CCAAGCGAAC  GCTTGGAACA  GGAACTCTTT  TCCGGAGGCA  ACACTGGGAT  TAACTTTGAG  480
481   AAATATGATG  ACATCCCGGT  TGAGGCGACA  GGGAATAACT  GCCCTCCACA  TATTGAAAGT  540
541   TTCAGCGATG  TCGAGATGGG  AGAGATTATT  ATGGGAAACA  TCGAGCTCAC  TCGTTACACA  600
601   CGCCCAACTC  CTGTGCAAAA  GCATGCTATT  CCTATTATCA  AGGAGAAAAG  AGACTTGATG  660
661   GCTTGTGCCC  AAACGGGGTC  TGGAAAAACA  GCAGCTTTTC  TTCTACCTAT  CTTGAGTCAG  720
721   ATCTATACGG  ATGGTCCAGG  TGAGGCTTTG  AGGGCCATGA  AGGAGAATGG  AAAGTATGGG  780
781   CGTCGCAAAC  AGTATCCAAT  CTCCTTGGTC  TTGGCTCCGA  CCAGAGAATT  GGCCGTGCAG  840
841   ATCTATGAGG  AGGCCAGGAA  ATTCTCATAC  CGCTCTCGAG  TTCGTCCTTG  TGTGGTTTAT  900
901   GGTGGAGCTG  ATATTGGGCA  GCAGATTCGA  GACTTGGAAC  GTGGCTGTCA  CTTGTTAGTA  960
961   GCTACTCCAG  GACGGCTAGT  AGATATGATG  GAGAGAGGAA  AGATTGGACT  GGACTTCTGC  1020
1021  AAATACTTGG  TGTTAGATGA  AGCAGATCGA  ATGTTGGACA  TGGGCTTTGA  GCCTCAGATA  1080
1081  CGAAGAATAG  TTGAGCAAGA  CACCATGCCT  CCAAAAGGTG  TCCGCCACAC  TATGATGTTT  1140
1141  AGTGCTACCT  TTCCTAAGGA  AATACAGATG  CTGGCTCGGG  ATTTCTTGGA  TGAATATATC  1200
1201  TTTCTGGCCG  TAGGAAGAGT  TGGGTCTACT  TCTGAGAACA  TCACACAGAA  AGTCGTGTGG  1260
1261  GTGGAAGAAG  CAGACAAGCG  GTCATTTCTG  CTTGACCTCC  TGAATGCAAC  GGGCAAGGAT  1320
1321  TCCCTGATAT  TGGTGTTTGT  GGAAACCAAA  AAGGGTGCAG  ATTCTCTGGA  GGACTTCTTA  1380
1381  TACCACGAAG  GATATGCTTG  TACCAGTATC  CATGGAGACC  GATCTCAGCG  AGATAGGGAA  1440
1441  GAGGCCCTTC  ACCAATTCCG  ATCAGGAAAA  AGCCCAATTC  TCGTGGCTAC  AGCAGTAGCT  1500
1501  GCAAGAGGAC  TGGATATTTC  CAATGTGAAA  CATGTCATCA  ATTTCGACTT  GCCTAGTGAC  1560
1561  ATCGAAGAAT  ATGTGCATCG  CATTGGCCGT  ACAGGTCGTG  TTGGAAACCT  TGGCCTTGCC  1620
1621  ACCTCATTCT  TCAACGAGAG  GAACATAAAT  ATTACCAAAG  ATTTATTGGA  TCTTCTTGTT  1680
1681  GAAGCAAAAC  AAGAAGTGCC  ATCTTGGCTA  GAAAACATGG  CTTTTGAACA  CCATTACAAG  1740
1741  GGTGGCAGTC  GTGGACGGTC  CAAGAGCAGA  TTTAGTGGAG  GATTTGGTGC  TAGAGACTAT  1800
1801  CGACAAAGTA  GCGGTGCCAG  CAGTTCCAGC  TTCAGCAGTG  GCCGTGCTAG  CAACAGTCGC  1860
1861  AGCGGTGGAG  GCAGCCATGG  CAGCAGCAGA  GGGTTTGGTG  GAGGTAGCTA  TGGAGGCTTT  1920
1921  TACAACAGTG  ATGGATATGG  AGGAAATTAT  AGCTCCCAGG  GGGTTGACTG  GTGGGGTAAC  1980
1981  TGA  1983

▼ KEYWORD

ID
Family
Acetylation
ATP-binding
Complete proteome
Developmental protein
Differentiation
DNA-binding
Helicase
Hydrolase
Isopeptide bond
Methylation
Nucleotide-binding
Phosphoprotein
Reference proteome
Repeat
RNA-binding
Spermatogenesis
Ubl conjugation

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
ATP binding
Molecular Function
DNA binding
Molecular Function
Helicase activity
Molecular Function
RNA binding
Biological Process
Cell differentiation
Biological Process
Multicellular organism development
Biological Process
Spermatogenesis

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-0132Monodelphis domestica98.480.0 808
LLPS-Fia-0134Ficedula albicollis96.940.0 925
LLPS-Ran-1686Rattus norvegicus96.550.01052
LLPS-Mea-2174Mesocricetus auratus95.720.01029
LLPS-Ict-0841Ictidomys tridecemlineatus93.930.01021
LLPS-Pat-2913Pan troglodytes93.460.01027
LLPS-Pap-3592Pan paniscus93.460.01026
LLPS-Maf-1556Macaca fascicularis93.290.01027
LLPS-Cea-0524Cercocebus atys93.290.01026
LLPS-Gog-2187Gorilla gorilla93.290.01025
LLPS-Caj-0386Callithrix jacchus93.290.01025
LLPS-Mup-2253Mustela putorius furo93.290.01026
LLPS-Paa-2699Papio anubis93.290.01027
LLPS-Mal-3799Mandrillus leucophaeus93.290.01027
LLPS-Fec-2212Felis catus93.290.01027
LLPS-Hos-1500Homo sapiens93.290.01025
LLPS-Man-1590Macaca nemestrina93.290.01027
LLPS-Poa-1149Pongo abelii93.290.01027
LLPS-Mam-1049Macaca mulatta93.290.01027
LLPS-Aim-0813Ailuropoda melanoleuca93.130.01023
LLPS-Otg-1214Otolemur garnettii93.120.01026
LLPS-Eqc-2633Equus caballus93.120.01029
LLPS-Cas-1020Carlito syrichta93.120.01027
LLPS-Ere-0702Erinaceus europaeus93.040.01011
LLPS-Cap-1989Cavia porcellus93.040.01016
LLPS-Tut-0044Tursiops truncatus92.860.01005
LLPS-Aon-1050Aotus nancymaae92.770.01026
LLPS-Orc-3023Oryctolagus cuniculus92.770.01023
LLPS-Sus-0243Sus scrofa92.60.01023
LLPS-Myl-2678Myotis lucifugus92.60.01021
LLPS-Loa-0416Loxodonta africana92.60.01022
LLPS-Fud-1208Fukomys damarensis92.430.01017
LLPS-Ora-0327Ornithorhynchus anatinus91.620.01002
LLPS-Sah-0623Sarcophilus harrisii91.60.01008
LLPS-Bot-0040Bos taurus91.050.01024
LLPS-Ova-1257Ovis aries91.050.01024
LLPS-Urm-2683Ursus maritimus90.890.01009
LLPS-Dio-1670Dipodomys ordii90.530.01000
LLPS-Tag-1133Taeniopygia guttata89.760.0 968
LLPS-Pes-0239Pelodiscus sinensis88.930.0 980
LLPS-Rhb-1494Rhinopithecus bieti88.770.0 940
LLPS-Xim-2094Xiphophorus maculatus88.740.0 853
LLPS-Orn-3981Oreochromis niloticus88.720.0 853
LLPS-Pof-1094Poecilia formosa88.530.0 853
LLPS-Dar-0803Danio rerio88.50.0 852
LLPS-Nol-1346Nomascus leucogenys88.470.0 954
LLPS-Anp-1313Anas platyrhynchos88.380.0 964
LLPS-Meg-0145Meleagris gallopavo88.350.0 984
LLPS-Chs-3343Chlorocebus sabaeus88.180.0 646
LLPS-Scm-0014Scophthalmus maximus88.180.0 852
LLPS-Gaga-0499Gallus gallus87.910.0 993
LLPS-Tar-1197Takifugu rubripes87.420.0 848
LLPS-Caf-0362Canis familiaris86.720.01002
LLPS-Ten-2174Tetraodon nigroviridis86.670.0 835
LLPS-Orl-2540Oryzias latipes84.930.0 758
LLPS-Lac-3119Latimeria chalumnae84.040.0 890
LLPS-Leo-0557Lepisosteus oculatus82.990.0 872
LLPS-Gaa-0002Gasterosteus aculeatus81.120.0 785
LLPS-Asm-1533Astyanax mexicanus80.760.0 875
LLPS-Icp-3663Ictalurus punctatus79.850.0 852
LLPS-Anc-2061Anolis carolinensis78.640.0 932
LLPS-Xet-0247Xenopus tropicalis78.630.0 919
LLPS-Scf-1840Scleropages formosus75.420.0 867
LLPS-Cii-0230Ciona intestinalis72.830.0 691
LLPS-Drm-0055Drosophila melanogaster68.610.0 645
LLPS-Lem-0887Leptosphaeria maculans66.590.0 599
LLPS-Phn-1514Phaeosphaeria nodorum66.140.0 595
LLPS-Dos-1340Dothistroma septosporum65.170.0 592
LLPS-Pytr-0846Pyrenophora triticirepentis65.020.0 590
LLPS-Coo-0958Colletotrichum orbiculare64.650.0 581
LLPS-Abg-0167Absidia glauca64.650.0 582
LLPS-Asni-0231Aspergillus niger64.640.0 585
LLPS-Pyt-1031Pyrenophora teres64.60.0 594
LLPS-Nec-1174Neurospora crassa64.590.0 579
LLPS-Trr-1093Trichoderma reesei64.590.0 580
LLPS-Trv-1134Trichoderma virens64.590.0 577
LLPS-Zyt-0326Zymoseptoria tritici64.524e-161 479
LLPS-Cogr-0803Colletotrichum graminicola64.440.0 582
LLPS-Asn-0844Aspergillus nidulans64.410.0 583
LLPS-Blg-1064Blumeria graminis64.410.0 570
LLPS-Aso-0181Aspergillus oryzae64.190.0 585
LLPS-Asf-0594Aspergillus flavus64.190.0 586
LLPS-Nef-0280Neosartorya fischeri64.190.0 583
LLPS-Asfu-0639Aspergillus fumigatus64.190.0 583
LLPS-Fus-0112Fusarium solani64.140.0 578
LLPS-Ast-1078Aspergillus terreus63.960.0 582
LLPS-Fuv-0774Fusarium verticillioides63.920.0 577
LLPS-Fuo-0181Fusarium oxysporum63.920.0 576
LLPS-Asc-0143Aspergillus clavatus63.740.0 580
LLPS-Scs-0867Sclerotinia sclerotiorum63.720.0 570
LLPS-Sei-2128Setaria italica63.643e-156 464
LLPS-Gag-1612Gaeumannomyces graminis63.450.0 550
LLPS-Beb-1004Beauveria bassiana63.030.0 570
LLPS-Yal-0111Yarrowia lipolytica62.950.0 572
LLPS-Mao-1606Magnaporthe oryzae62.750.0 555
LLPS-Usm-0085Ustilago maydis62.50.0 570
LLPS-Mel-0135Melampsora laricipopulina62.440.0 571
LLPS-Ved-0384Verticillium dahliae62.440.0 550
LLPS-Crn-0659Cryptococcus neoformans62.220.0 538
LLPS-Spr-0926Sporisorium reilianum62.110.0 575
LLPS-Chc-0440Chondrus crispus62.03e-180 535
LLPS-Asg-0462Ashbya gossypii61.830.0 560
LLPS-Sob-1038Sorghum bicolor61.770.0 537
LLPS-Lep-0847Leersia perrieri61.590.0 544
LLPS-Miv-0275Microbotryum violaceum61.590.0 556
LLPS-Via-0724Vigna angularis61.540.0 538
LLPS-Mua-0520Musa acuminata61.360.0 539
LLPS-Ors-1577Oryza sativa61.210.0 547
LLPS-Orm-0065Oryza meridionalis61.210.0 547
LLPS-Coc-0261Corchorus capsularis61.214e-180 535
LLPS-Org-0682Oryza glaberrima61.210.0 548
LLPS-Pug-0846Puccinia graminis61.110.0 573
LLPS-Zem-2513Zea mays61.070.0 539
LLPS-Cae-0337Caenorhabditis elegans61.00.0 570
LLPS-Pot-0975Populus trichocarpa60.893e-175 520
LLPS-Put-0002Puccinia triticina60.890.0 571
LLPS-Viv-0371Vitis vinifera60.880.0 542
LLPS-Gor-1083Gossypium raimondii60.780.0 543
LLPS-Orp-0678Oryza punctata60.690.0 544
LLPS-Thc-0319Theobroma cacao60.550.0 539
LLPS-Scc-1144Schizosaccharomyces cryophilus60.540.0 539
LLPS-Glm-0687Glycine max60.423e-180 532
LLPS-Tra-0880Triticum aestivum60.420.0 541
LLPS-Hov-0608Hordeum vulgare60.420.0 541
LLPS-Brr-1390Brassica rapa60.421e-180 535
LLPS-Mae-1008Manihot esculenta60.420.0 538
LLPS-Orbr-0559Oryza brachyantha60.322e-180 536
LLPS-Brd-0509Brachypodium distachyon60.270.0 543
LLPS-Sac-1446Saccharomyces cerevisiae60.270.0 544
LLPS-Arl-0891Arabidopsis lyrata60.199e-180 533
LLPS-Nia-2420Nicotiana attenuata60.190.0 537
LLPS-Prp-0019Prunus persica60.191e-180 535
LLPS-Cus-0506Cucumis sativus60.130.0 548
LLPS-Brn-0237Brassica napus60.094e-180 533
LLPS-Scp-0261Schizosaccharomyces pombe60.090.0 536
LLPS-Met-1055Medicago truncatula60.090.0 544
LLPS-Sot-1273Solanum tuberosum59.950.0 536
LLPS-Art-1439Arabidopsis thaliana59.952e-178 530
LLPS-Scj-0642Schizosaccharomyces japonicus59.910.0 539
LLPS-Bro-0509Brassica oleracea59.862e-179 532
LLPS-Phv-0170Phaseolus vulgaris59.550.0 541
LLPS-Orr-1394Oryza rufipogon59.413e-180 533
LLPS-Hea-0687Helianthus annuus59.320.0 536
LLPS-Ori-2231Oryza indica59.181e-179 530
LLPS-Orgl-0084Oryza glumaepatula59.187e-179 530
LLPS-Amt-0341Amborella trichopoda59.175e-177 526
LLPS-Orb-0447Oryza barthii59.00.0 540
LLPS-Orni-0987Oryza nivara59.00.0 540
LLPS-Cym-0711Cyanidioschyzon merolae58.971e-169 506
LLPS-Tru-0229Triticum urartu58.910.0 548
LLPS-Vir-1749Vigna radiata58.734e-179 530
LLPS-Kop-0414Komagataella pastoris58.610.0 541
LLPS-Sol-0062Solanum lycopersicum58.493e-179 530
LLPS-Dac-0808Daucus carota58.440.0 536
LLPS-Php-1175Physcomitrella patens58.050.0 536
LLPS-Gas-0767Galdieria sulphuraria57.681e-178 529
LLPS-Osl-0707Ostreococcus lucimarinus57.346e-166 491
LLPS-Sem-0346Selaginella moellendorffii57.118e-179 525