LLPS-Zyt-1143
LIA1
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Deoxyhypusine hydroxylase |
| Gene Name: | LIA1, MYCGRDRAFT_62164 |
| Ensembl Gene: | Mycgr3G62164 |
| Ensembl Protein: | Mycgr3P62164 |
| Organism: | Zymoseptoria tritici |
| Taxa ID: | 336722 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Mycgr3T62164 | Mycgr3P62164 |
| UniProt | F9XJ37, F9XJ37_ZYMTI | |
| GeneBank | CM001204 | EGP84785.1 |
| RefSeq | XM_003849761.1 | XP_003849809.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSPAATLPED TVVSSLRSSL CNETAPLGQR FRDLFSLKHL ASQNPATEQS IPAVEAIAAA 60 61 LVSDSALLKH ELAYCLGQSG KEEAIPFLRA VIEDRQEDAM CRHEAAEAIA ALGDWNSLGL 120 121 LKERRDDKSE EEVVRETCDI AVERIEWLHS EEGKKETLKT SDFSSIDPAP PMAAQADTPS 180 181 IPELERSLLD TKLPLFLRYR AMFALRDLAS PPDLPTAVPA VNALAAGRKD PSALFRHEIA 240 241 FVFGQLSHPA SIPCLTEMLG NAKEASMVRH EAAEALGSLG DEPGVEDTLK KFLNDPEQVV 300 301 RDSIIVALDM ADFERSGETE YATIPIAQAA 330 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGCCCG CCGCTACACT CCCAGAAGAC ACCGTCGTCT CCAGCCTCCG CTCTTCCCTC 60 61 TGCAACGAGA CCGCCCCACT CGGCCAACGT TTCCGCGATC TCTTCTCTCT CAAACATCTC 120 121 GCTTCGCAGA ACCCCGCGAC TGAACAATCC ATCCCCGCAG TCGAGGCGAT CGCTGCAGCG 180 181 CTGGTTTCCG ACTCTGCTCT TCTTAAACAT GAGTTAGCGT ACTGTCTTGG CCAGTCGGGA 240 241 AAGGAGGAGG CGATACCTTT TCTACGAGCG GTGATTGAGG ATCGACAGGA GGATGCGATG 300 301 TGCAGACATG AGGCGGCAGA GGCAATTGCT GCGTTGGGAG ATTGGAATAG TTTGGGGCTG 360 361 CTGAAGGAGA GGAGGGACGA TAAGTCGGAG GAGGAAGTTG TCAGGGAGAC GTGTGATATT 420 421 GCGGTGGAGA GGATTGAGTG GTTACATTCT GAGGAGGGGA AGAAGGAGAC TTTGAAGACG 480 481 AGCGACTTCT CCTCCATCGA TCCAGCACCT CCGATGGCAG CGCAAGCCGA CACACCTTCC 540 541 ATTCCCGAAC TCGAACGATC ACTACTAGAC ACCAAGCTTC CACTCTTCCT CCGATACCGA 600 601 GCCATGTTCG CGCTCCGCGA TCTCGCTTCA CCACCAGATC TTCCCACAGC CGTTCCCGCC 660 661 GTCAACGCTC TCGCAGCAGG ACGCAAAGAT CCCTCAGCAC TCTTCCGCCA TGAAATCGCA 720 721 TTCGTCTTCG GACAACTATC GCATCCGGCT TCCATTCCGT GTCTGACGGA AATGCTGGGC 780 781 AATGCGAAAG AGGCGAGCAT GGTTCGACAT GAGGCTGCTG AAGCGCTCGG TAGTTTGGGC 840 841 GACGAGCCGG GTGTTGAGGA TACGCTCAAG AAGTTCCTGA ATGATCCAGA GCAGGTGGTG 900 901 AGGGATAGTA TTATCGTGGC GCTGGATATG GCGGACTTTG AGAGGAGTGG CGAAACGGAG 960 961 TATGCCACGA TTCCAATCGC TCAGGCGGCG TAG 993 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytoplasm | |
Cellular Component | Nucleus | |
Molecular Function | Deoxyhypusine monooxygenase activity | |
Molecular Function | Metal ion binding | |
Biological Process | Microtubule cytoskeleton organization | |
Biological Process | Peptidyl-lysine modification to peptidyl-hypusine |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Dos-0912 | Dothistroma septosporum | 78.79 | 0.0 | 511 |
| LLPS-Lem-0395 | Leptosphaeria maculans | 72.31 | 8e-157 | 449 |
| LLPS-Phn-1113 | Phaeosphaeria nodorum | 72.31 | 7e-165 | 470 |
| LLPS-Pyt-0976 | Pyrenophora teres | 71.47 | 2e-163 | 466 |
| LLPS-Pytr-1545 | Pyrenophora triticirepentis | 71.47 | 1e-162 | 464 |
| LLPS-Asni-1604 | Aspergillus niger | 70.93 | 2e-156 | 449 |
| LLPS-Asn-1294 | Aspergillus nidulans | 69.94 | 2e-154 | 444 |
| LLPS-Map-1169 | Magnaporthe poae | 69.91 | 6e-95 | 288 |
| LLPS-Trv-0317 | Trichoderma virens | 68.47 | 1e-137 | 400 |
| LLPS-Trr-1483 | Trichoderma reesei | 68.25 | 3e-138 | 402 |
| LLPS-Nec-0510 | Neurospora crassa | 68.15 | 9e-143 | 414 |
| LLPS-Ast-0523 | Aspergillus terreus | 68.04 | 1e-146 | 424 |
| LLPS-Asc-1136 | Aspergillus clavatus | 67.68 | 8e-155 | 445 |
| LLPS-Nef-0946 | Neosartorya fischeri | 67.57 | 1e-155 | 447 |
| LLPS-Scs-0550 | Sclerotinia sclerotiorum | 67.16 | 7e-142 | 412 |
| LLPS-Asf-0737 | Aspergillus flavus | 66.87 | 8e-152 | 437 |
| LLPS-Mao-0641 | Magnaporthe oryzae | 65.97 | 3e-140 | 407 |
| LLPS-Fus-1090 | Fusarium solani | 65.29 | 1e-135 | 396 |
| LLPS-Fuo-0385 | Fusarium oxysporum | 65.15 | 4e-136 | 397 |
| LLPS-Blg-1515 | Blumeria graminis | 65.09 | 4e-135 | 394 |
| LLPS-Gag-0826 | Gaeumannomyces graminis | 64.98 | 2e-118 | 352 |
| LLPS-Fuv-0156 | Fusarium verticillioides | 64.55 | 8e-135 | 394 |
| LLPS-Beb-1196 | Beauveria bassiana | 64.44 | 2e-131 | 385 |
| LLPS-Cogr-0193 | Colletotrichum graminicola | 64.43 | 4e-141 | 410 |
| LLPS-Ved-0856 | Verticillium dahliae | 64.09 | 3e-132 | 387 |
| LLPS-Coo-0911 | Colletotrichum orbiculare | 63.05 | 3e-141 | 410 |
| LLPS-Asfu-1326 | Aspergillus fumigatus | 62.78 | 5e-150 | 434 |
| LLPS-Aso-1161 | Aspergillus oryzae | 62.65 | 8e-142 | 412 |
| LLPS-Cog-1246 | Colletotrichum gloeosporioides | 60.51 | 4e-115 | 343 |
| LLPS-Tum-0081 | Tuber melanosporum | 52.01 | 2e-85 | 266 |
| LLPS-Sac-0010 | Saccharomyces cerevisiae | 49.22 | 1e-85 | 268 |
| LLPS-Yal-0539 | Yarrowia lipolytica | 48.92 | 2e-88 | 275 |
| LLPS-Asg-1046 | Ashbya gossypii | 48.73 | 2e-80 | 254 |
| LLPS-Abg-1750 | Absidia glauca | 48.68 | 8e-75 | 254 |
| LLPS-Tar-3610 | Takifugu rubripes | 48.66 | 1e-76 | 244 |
| LLPS-Orl-3320 | Oryzias latipes | 48.55 | 1e-76 | 244 |
| LLPS-Gaa-0939 | Gasterosteus aculeatus | 47.84 | 5e-75 | 240 |
| LLPS-Xim-2008 | Xiphophorus maculatus | 47.78 | 8e-78 | 247 |
| LLPS-Kop-0859 | Komagataella pastoris | 47.34 | 4e-91 | 281 |
| LLPS-Leo-0358 | Lepisosteus oculatus | 47.28 | 3e-78 | 248 |
| LLPS-Pug-0037 | Puccinia graminis | 47.2 | 5e-72 | 233 |
| LLPS-Put-1257 | Puccinia triticina | 46.85 | 2e-70 | 228 |
| LLPS-Miv-0999 | Microbotryum violaceum | 46.82 | 1e-71 | 232 |
| LLPS-Dar-0792 | Danio rerio | 46.69 | 8e-79 | 249 |
| LLPS-Orn-3580 | Oreochromis niloticus | 46.67 | 2e-79 | 251 |
| LLPS-Asm-1102 | Astyanax mexicanus | 46.15 | 5e-76 | 243 |
| LLPS-Mel-1098 | Melampsora laricipopulina | 45.95 | 2e-74 | 239 |
| LLPS-Pof-4197 | Poecilia formosa | 45.66 | 4e-44 | 157 |
| LLPS-Icp-3389 | Ictalurus punctatus | 45.6 | 1e-74 | 239 |
| LLPS-Ten-2886 | Tetraodon nigroviridis | 45.51 | 2e-72 | 233 |
| LLPS-Fia-2282 | Ficedula albicollis | 45.48 | 4e-70 | 227 |
| LLPS-Crn-1049 | Cryptococcus neoformans | 45.02 | 8e-66 | 218 |
| LLPS-Scf-1863 | Scleropages formosus | 45.02 | 4e-74 | 238 |
| LLPS-Spr-1140 | Sporisorium reilianum | 44.9 | 4e-74 | 239 |
| LLPS-Scp-1140 | Schizosaccharomyces pombe | 44.89 | 1e-76 | 244 |
| LLPS-Gaga-1688 | Gallus gallus | 44.84 | 5e-67 | 219 |
| LLPS-Lac-3935 | Latimeria chalumnae | 44.62 | 3e-73 | 235 |
| LLPS-Meg-2183 | Meleagris gallopavo | 44.52 | 2e-66 | 218 |
| LLPS-Ran-3876 | Rattus norvegicus | 44.19 | 9e-71 | 229 |
| LLPS-Scj-0357 | Schizosaccharomyces japonicus | 44.17 | 1e-74 | 239 |
| LLPS-Cap-1607 | Cavia porcellus | 43.91 | 6e-64 | 211 |
| LLPS-Bot-0260 | Bos taurus | 43.87 | 6e-66 | 216 |
| LLPS-Drm-0620 | Drosophila melanogaster | 43.87 | 6e-72 | 232 |
| LLPS-Cii-1023 | Ciona intestinalis | 43.79 | 4e-68 | 222 |
| LLPS-Nol-4183 | Nomascus leucogenys | 43.78 | 3e-40 | 147 |
| LLPS-Aim-2966 | Ailuropoda melanoleuca | 43.77 | 5e-65 | 214 |
| LLPS-Usm-1286 | Ustilago maydis | 43.77 | 6e-72 | 234 |
| LLPS-Sah-1918 | Sarcophilus harrisii | 43.73 | 2e-63 | 210 |
| LLPS-Scc-0003 | Schizosaccharomyces cryophilus | 43.57 | 1e-72 | 234 |
| LLPS-Aon-2867 | Aotus nancymaae | 43.55 | 3e-62 | 207 |
| LLPS-Mum-4784 | Mus musculus | 43.55 | 4e-69 | 224 |
| LLPS-Mup-1252 | Mustela putorius furo | 43.55 | 3e-65 | 214 |
| LLPS-Fec-4605 | Felis catus | 43.55 | 4e-65 | 214 |
| LLPS-Eqc-4804 | Equus caballus | 43.55 | 8e-58 | 195 |
| LLPS-Dio-4371 | Dipodomys ordii | 43.48 | 4e-19 | 86.3 |
| LLPS-Ict-1446 | Ictidomys tridecemlineatus | 43.42 | 7e-66 | 216 |
| LLPS-Cea-4603 | Cercocebus atys | 43.23 | 9e-65 | 214 |
| LLPS-Maf-1324 | Macaca fascicularis | 43.23 | 2e-64 | 213 |
| LLPS-Chs-4821 | Chlorocebus sabaeus | 43.23 | 3e-64 | 212 |
| LLPS-Paa-2980 | Papio anubis | 43.23 | 1e-64 | 213 |
| LLPS-Man-4223 | Macaca nemestrina | 43.23 | 1e-64 | 213 |
| LLPS-Caf-3188 | Canis familiaris | 43.23 | 9e-65 | 213 |
| LLPS-Poa-1684 | Pongo abelii | 43.23 | 2e-64 | 212 |
| LLPS-Mod-1035 | Monodelphis domestica | 42.91 | 4e-47 | 169 |
| LLPS-Sus-4312 | Sus scrofa | 42.9 | 2e-62 | 207 |
| LLPS-Hos-2918 | Homo sapiens | 42.9 | 4e-64 | 211 |
| LLPS-Pat-4074 | Pan troglodytes | 42.9 | 6e-64 | 211 |
| LLPS-Otg-1465 | Otolemur garnettii | 42.9 | 9e-65 | 213 |
| LLPS-Chc-0809 | Chondrus crispus | 42.59 | 1e-62 | 209 |
| LLPS-Loa-0691 | Loxodonta africana | 42.48 | 2e-41 | 149 |
| LLPS-Gog-3515 | Gorilla gorilla | 42.42 | 5e-43 | 155 |
| LLPS-Ora-2820 | Ornithorhynchus anatinus | 42.35 | 3e-48 | 169 |
| LLPS-Cae-1749 | Caenorhabditis elegans | 42.09 | 7e-67 | 218 |
| LLPS-Brr-0673 | Brassica rapa | 42.08 | 2e-43 | 156 |
| LLPS-Hov-1710 | Hordeum vulgare | 41.96 | 6e-44 | 159 |
| LLPS-Mea-3583 | Mesocricetus auratus | 41.94 | 3e-59 | 199 |
| LLPS-Pap-3339 | Pan paniscus | 41.94 | 1e-58 | 197 |
| LLPS-Pot-1812 | Populus trichocarpa | 41.49 | 5e-54 | 186 |
| LLPS-Pes-1615 | Pelodiscus sinensis | 41.29 | 4e-61 | 203 |
| LLPS-Thc-1922 | Theobroma cacao | 41.25 | 9e-54 | 184 |
| LLPS-Coc-1321 | Corchorus capsularis | 41.07 | 3e-10 | 63.9 |
| LLPS-Vir-0999 | Vigna radiata | 41.01 | 8e-33 | 130 |
| LLPS-Viv-0362 | Vitis vinifera | 40.98 | 2e-51 | 179 |
| LLPS-Gas-0657 | Galdieria sulphuraria | 40.97 | 2e-55 | 189 |
| LLPS-Orm-1967 | Oryza meridionalis | 40.67 | 2e-50 | 176 |
| LLPS-Fud-3973 | Fukomys damarensis | 40.65 | 3e-26 | 107 |
| LLPS-Ova-0176 | Ovis aries | 40.65 | 4e-53 | 182 |
| LLPS-Orbr-2206 | Oryza brachyantha | 40.58 | 3e-53 | 184 |
| LLPS-Orb-1015 | Oryza barthii | 40.33 | 8e-51 | 177 |
| LLPS-Orni-0231 | Oryza nivara | 40.33 | 8e-51 | 177 |
| LLPS-Orgl-2222 | Oryza glumaepatula | 40.33 | 8e-51 | 177 |
| LLPS-Ors-0172 | Oryza sativa | 40.33 | 4e-50 | 175 |
| LLPS-Orr-0156 | Oryza rufipogon | 40.33 | 2e-50 | 176 |
| LLPS-Org-1931 | Oryza glaberrima | 40.33 | 2e-50 | 176 |
| LLPS-Mae-2114 | Manihot esculenta | 40.32 | 7e-52 | 180 |
| LLPS-Tra-0284 | Triticum aestivum | 40.2 | 9e-49 | 172 |
| LLPS-Glm-0788 | Glycine max | 40.13 | 2e-50 | 176 |
| LLPS-Lep-0972 | Leersia perrieri | 40.13 | 9e-50 | 174 |
| LLPS-Phv-1843 | Phaseolus vulgaris | 40.13 | 3e-53 | 184 |
| LLPS-Ori-1777 | Oryza indica | 40.0 | 5e-50 | 175 |
| LLPS-Chr-0469 | Chlamydomonas reinhardtii | 40.0 | 1e-58 | 197 |
| LLPS-Orp-1278 | Oryza punctata | 40.0 | 5e-49 | 172 |
| LLPS-Brn-2832 | Brassica napus | 39.94 | 8e-50 | 175 |
| LLPS-Caj-3953 | Callithrix jacchus | 39.94 | 4e-56 | 191 |
| LLPS-Via-0380 | Vigna angularis | 39.81 | 3e-50 | 177 |
| LLPS-Zem-0605 | Zea mays | 39.68 | 1e-48 | 172 |
| LLPS-Hea-2717 | Helianthus annuus | 39.67 | 3e-54 | 186 |
| LLPS-Brd-2385 | Brachypodium distachyon | 39.67 | 1e-49 | 174 |
| LLPS-Sob-2544 | Sorghum bicolor | 39.67 | 5e-48 | 170 |
| LLPS-Cis-1492 | Ciona savignyi | 39.55 | 2e-60 | 201 |
| LLPS-Tru-1140 | Triticum urartu | 39.46 | 3e-45 | 162 |
| LLPS-Met-1212 | Medicago truncatula | 39.4 | 1e-50 | 177 |
| LLPS-Sei-2442 | Setaria italica | 39.33 | 5e-47 | 167 |
| LLPS-Urm-1057 | Ursus maritimus | 39.32 | 8e-15 | 77.0 |
| LLPS-Cus-1496 | Cucumis sativus | 39.26 | 2e-17 | 85.1 |
| LLPS-Xet-0999 | Xenopus tropicalis | 39.24 | 3e-51 | 178 |
| LLPS-Prp-2536 | Prunus persica | 39.21 | 2e-52 | 181 |
| LLPS-Amt-1710 | Amborella trichopoda | 39.17 | 6e-48 | 170 |
| LLPS-Art-2368 | Arabidopsis thaliana | 39.07 | 5e-53 | 183 |
| LLPS-Gor-1624 | Gossypium raimondii | 38.94 | 1e-50 | 177 |
| LLPS-Arl-2071 | Arabidopsis lyrata | 38.74 | 9e-52 | 180 |
| LLPS-Dac-2119 | Daucus carota | 38.69 | 3e-48 | 171 |
| LLPS-Cym-0972 | Cyanidioschyzon merolae | 38.51 | 1e-16 | 82.8 |
| LLPS-Bro-0578 | Brassica oleracea | 38.14 | 7e-41 | 152 |
| LLPS-Php-1338 | Physcomitrella patens | 37.93 | 3e-45 | 163 |
| LLPS-Sem-1163 | Selaginella moellendorffii | 37.86 | 3e-46 | 165 |
| LLPS-Sol-1289 | Solanum lycopersicum | 37.75 | 6e-45 | 162 |
| LLPS-Sot-1193 | Solanum tuberosum | 37.75 | 2e-44 | 161 |
| LLPS-Mua-2263 | Musa acuminata | 37.72 | 3e-10 | 64.3 |
| LLPS-Nia-1663 | Nicotiana attenuata | 37.42 | 3e-45 | 163 |
| LLPS-Mal-1632 | Mandrillus leucophaeus | 34.69 | 2e-39 | 145 |
| LLPS-Rhb-2066 | Rhinopithecus bieti | 34.52 | 1e-38 | 143 |
| LLPS-Osl-1433 | Ostreococcus lucimarinus | 34.45 | 2e-32 | 127 |