• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Orb-1015

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Deoxyhypusine hydroxylase
Ensembl Gene: OBART12G03840
Ensembl Protein: OBART12G03840.1
Organism: Oryza barthii
Taxa ID: 65489
LLPS Type: Client


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION


Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblOBART12G03840.1OBART12G03840.1
UniProtA0A0D3HRR5, A0A0D3HRR5_9ORYZ

▼ SEQUENCE


Protein Sequence (FASTA)
1     MESAEVAASS  TFGPTPEMEK  FLCDLLLDTA  QPIAERFRAL  FSLRNLHGDG  PRCALLQAAR  60
61    DSSNLLAHEA  AFALGQMQDA  EAIPALEAVL  KDLSLHPIVR  HEAAEALGAI  GLEKSIPLLE  120
121   ESLAADPAVE  VQETCELALR  RIEQQKNAGV  SESTTISPFL  SVDPALPAKQ  GLSVHQLREI  180
181   LLNEQESMYE  RYAALFALRN  DSGDAAVSAI  VAALGAKSAL  LKHEVAYVLG  QLQNKAASDA  240
241   LSTVLKNVDE  HPMVRHEAAE  ALGSIADQES  IALLEEFAKD  PEPIVSQSCE  VALSMLEYER  300
301   SGKSFETPGV  QQES  314
Nucleotide CDS Sequence (FASTA)
1     ATGGAGTCGG  CAGAGGTGGC  TGCTTCTTCC  ACATTCGGGC  CTACCCCAGA  GATGGAGAAG  60
61    TTCCTGTGCG  ATCTGCTGCT  GGACACGGCA  CAGCCCATCG  CTGAACGCTT  CCGTGCGCTC  120
121   TTCTCCCTCC  GCAACCTCCA  TGGTGATGGC  CCCCGCTGCG  CCCTCCTCCA  AGCTGCAAGG  180
181   GATTCTTCTA  ACTTGCTTGC  CCATGAGGCT  GCTTTTGCAC  TTGGACAAAT  GCAAGATGCT  240
241   GAGGCTATCC  CTGCGTTAGA  GGCAGTTCTC  AAAGATCTTT  CACTTCATCC  AATTGTCCGC  300
301   CATGAGGCTG  CGGAAGCCCT  TGGTGCTATT  GGCCTGGAGA  AGAGCATTCC  CCTGCTTGAG  360
361   GAGAGTTTAG  CTGCTGATCC  TGCCGTGGAG  GTTCAGGAAA  CATGTGAGCT  GGCTCTTAGG  420
421   CGGATAGAAC  AACAAAAGAA  TGCTGGTGTT  TCTGAAAGCA  CAACCATTTC  ACCATTTCTC  480
481   TCAGTTGATC  CAGCATTACC  TGCAAAGCAA  GGACTTTCGG  TACACCAACT  AAGGGAGATT  540
541   CTTCTCAACG  AACAAGAAAG  CATGTATGAA  CGTTATGCGG  CTCTTTTTGC  ACTAAGGAAT  600
601   GATAGCGGAG  ATGCTGCTGT  TTCTGCTATA  GTTGCAGCTC  TAGGTGCCAA  AAGTGCCCTT  660
661   CTAAAGCATG  AGGTTGCTTA  TGTGTTAGGT  CAGCTGCAAA  ATAAAGCTGC  TTCGGATGCG  720
721   CTTTCCACCG  TCCTGAAGAA  TGTTGATGAG  CATCCAATGG  TCAGGCATGA  AGCTGCTGAG  780
781   GCCCTTGGTT  CAATTGCAGA  TCAAGAAAGC  ATTGCACTTC  TGGAGGAATT  CGCCAAGGAT  840
841   CCTGAGCCTA  TAGTCTCCCA  AAGCTGTGAA  GTCGCGCTCA  GCATGCTCGA  ATACGAGAGA  900
901   TCCGGAAAAT  CCTTCGAGAC  TCCTGGGGTG  CAGCAGGAGT  CCTGA  945

▼ KEYWORD


ID
Family
Coiled coil
Complete proteome
Hypusine biosynthesis
Iron
Metal-binding
Monooxygenase
Oxidoreductase
Reference proteome

▼ GENE ONTOLOGY


ID
Classification
Description
Molecular Function
Deoxyhypusine monooxygenase activity
Molecular Function
Metal ion binding
Biological Process
Peptidyl-lysine modification to peptidyl-hypusine

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orni-0231Oryza nivara100.00.0 565
LLPS-Orr-0156Oryza rufipogon99.680.0 565
LLPS-Orgl-2222Oryza glumaepatula99.680.0 563
LLPS-Orm-1967Oryza meridionalis98.730.0 557
LLPS-Org-1931Oryza glaberrima98.430.0 558
LLPS-Ors-0172Oryza sativa98.120.0 558
LLPS-Ori-1777Oryza indica98.120.0 556
LLPS-Orp-1278Oryza punctata95.610.0 536
LLPS-Lep-0972Leersia perrieri90.60.0 513
LLPS-Orbr-2206Oryza brachyantha90.094e-179 506
LLPS-Tru-1140Triticum urartu88.972e-138 402
LLPS-Hov-1710Hordeum vulgare88.735e-146 422
LLPS-Sei-2442Setaria italica87.142e-164 468
LLPS-Tra-0284Triticum aestivum87.015e-166 471
LLPS-Sob-2544Sorghum bicolor86.823e-164 467
LLPS-Brd-2385Brachypodium distachyon85.942e-167 476
LLPS-Zem-0605Zea mays80.248e-156 446
LLPS-Coc-1321Corchorus capsularis76.981e-109 327
LLPS-Gor-1624Gossypium raimondii76.452e-133 389
LLPS-Thc-1922Theobroma cacao76.371e-136 396
LLPS-Prp-2536Prunus persica75.838e-139 403
LLPS-Pot-1812Populus trichocarpa74.833e-128 376
LLPS-Mae-2114Manihot esculenta74.53e-133 389
LLPS-Hea-2717Helianthus annuus74.422e-133 389
LLPS-Cus-1496Cucumis sativus74.192e-131 384
LLPS-Sot-1193Solanum tuberosum74.02e-132 387
LLPS-Mua-2263Musa acuminata73.856e-108 323
LLPS-Sol-1289Solanum lycopersicum73.672e-132 387
LLPS-Nia-1663Nicotiana attenuata73.481e-134 393
LLPS-Brr-0673Brassica rapa73.442e-102 308
LLPS-Art-2368Arabidopsis thaliana73.293e-130 381
LLPS-Via-0380Vigna angularis73.227e-131 385
LLPS-Viv-0362Vitis vinifera72.845e-137 398
LLPS-Met-1212Medicago truncatula71.865e-129 378
LLPS-Glm-0788Glycine max71.853e-131 383
LLPS-Phv-1843Phaseolus vulgaris71.88e-132 385
LLPS-Amt-1710Amborella trichopoda71.716e-126 370
LLPS-Dac-2119Daucus carota71.71e-129 379
LLPS-Arl-2071Arabidopsis lyrata70.237e-131 382
LLPS-Brn-2832Brassica napus70.03e-125 369
LLPS-Bro-0578Brassica oleracea69.062e-123 365
LLPS-Sem-1163Selaginella moellendorffii60.553e-95 291
LLPS-Php-1338Physcomitrella patens60.276e-91 281
LLPS-Vir-0999Vigna radiata59.327e-97 299
LLPS-Chr-0469Chlamydomonas reinhardtii52.822e-70 228
LLPS-Urm-1057Ursus maritimus52.631e-1579.3
LLPS-Fia-2282Ficedula albicollis52.527e-72 231
LLPS-Fud-3973Fukomys damarensis52.521e-27 110
LLPS-Mum-4784Mus musculus52.356e-70 226
LLPS-Sah-1918Sarcophilus harrisii52.137e-70 226
LLPS-Ran-3876Rattus norvegicus52.135e-74 236
LLPS-Man-4223Macaca nemestrina51.773e-71 229
LLPS-Maf-1324Macaca fascicularis51.773e-71 229
LLPS-Aon-2867Aotus nancymaae51.777e-71 228
LLPS-Paa-2980Papio anubis51.774e-71 229
LLPS-Gaa-0939Gasterosteus aculeatus51.763e-70 227
LLPS-Dio-4371Dipodomys ordii51.436e-1779.7
LLPS-Chs-4821Chlorocebus sabaeus51.425e-70 226
LLPS-Cea-4603Cercocebus atys51.423e-70 227
LLPS-Xim-2008Xiphophorus maculatus51.276e-69 223
LLPS-Poa-1684Pongo abelii51.252e-71 229
LLPS-Gaga-1688Gallus gallus51.252e-68 222
LLPS-Tar-3610Takifugu rubripes51.251e-70 228
LLPS-Mod-1035Monodelphis domestica51.091e-49 175
LLPS-Orl-3320Oryzias latipes50.93e-70 227
LLPS-Meg-2183Meleagris gallopavo50.891e-66 217
LLPS-Hos-2918Homo sapiens50.894e-70 226
LLPS-Orn-3580Oreochromis niloticus50.716e-70 226
LLPS-Asm-1102Astyanax mexicanus50.711e-71 231
LLPS-Pof-4197Poecilia formosa50.585e-36 135
LLPS-Nol-4183Nomascus leucogenys50.549e-46 161
LLPS-Pat-4074Pan troglodytes50.532e-69 224
LLPS-Dar-0792Danio rerio50.532e-71 230
LLPS-Cap-1607Cavia porcellus50.535e-67 219
LLPS-Sus-4312Sus scrofa50.532e-70 227
LLPS-Ict-1446Ictidomys tridecemlineatus50.361e-66 218
LLPS-Ten-2886Tetraodon nigroviridis50.352e-66 217
LLPS-Icp-3389Ictalurus punctatus50.04e-67 219
LLPS-Pap-3339Pan paniscus49.828e-67 218
LLPS-Loa-0691Loxodonta africana49.757e-42 150
LLPS-Fec-4605Felis catus49.658e-69 223
LLPS-Mea-3583Mesocricetus auratus49.645e-63 208
LLPS-Ora-2820Ornithorhynchus anatinus49.578e-51 175
LLPS-Lac-3935Latimeria chalumnae49.473e-67 219
LLPS-Caf-3188Canis familiaris49.474e-69 224
LLPS-Bot-0260Bos taurus49.472e-67 219
LLPS-Mup-1252Mustela putorius furo49.472e-68 222
LLPS-Otg-1465Otolemur garnettii49.312e-67 219
LLPS-Leo-0358Lepisosteus oculatus48.943e-64 211
LLPS-Aim-2966Ailuropoda melanoleuca48.763e-64 211
LLPS-Eqc-4804Equus caballus48.759e-60 200
LLPS-Scf-1863Scleropages formosus48.753e-65 214
LLPS-Pes-1615Pelodiscus sinensis47.522e-60 201
LLPS-Gog-3515Gorilla gorilla47.266e-44 157
LLPS-Drm-0620Drosophila melanogaster47.124e-62 206
LLPS-Caj-3953Callithrix jacchus46.963e-63 209
LLPS-Pug-0037Puccinia graminis46.598e-1680.5
LLPS-Put-1257Puccinia triticina46.593e-1681.3
LLPS-Abg-1750Absidia glauca46.137e-50 183
LLPS-Mel-1098Melampsora laricipopulina45.671e-59 200
LLPS-Cae-1749Caenorhabditis elegans45.592e-25 107
LLPS-Cii-1023Ciona intestinalis44.371e-60 202
LLPS-Ova-0176Ovis aries44.375e-49 171
LLPS-Tum-0081Tuber melanosporum44.167e-52 179
LLPS-Crn-1049Cryptococcus neoformans43.71e-1785.9
LLPS-Osl-1433Ostreococcus lucimarinus43.625e-49 172
LLPS-Rhb-2066Rhinopithecus bieti43.529e-1884.7
LLPS-Xet-0999Xenopus tropicalis43.123e-1784.0
LLPS-Blg-1515Blumeria graminis43.072e-2196.3
LLPS-Gas-0657Galdieria sulphuraria42.354e-49 172
LLPS-Mal-1632Mandrillus leucophaeus42.281e-1784.7
LLPS-Trr-1483Trichoderma reesei42.271e-41 152
LLPS-Trv-0317Trichoderma virens42.185e-42 154
LLPS-Scp-1140Schizosaccharomyces pombe42.092e-52 181
LLPS-Scj-0357Schizosaccharomyces japonicus42.099e-49 172
LLPS-Chc-0809Chondrus crispus42.054e-46 166
LLPS-Beb-1196Beauveria bassiana42.034e-1784.0
LLPS-Lem-0395Leptosphaeria maculans41.911e-1271.2
LLPS-Nec-0510Neurospora crassa41.841e-40 150
LLPS-Yal-0539Yarrowia lipolytica41.752e-54 186
LLPS-Cis-1492Ciona savignyi41.374e-54 184
LLPS-Scc-0003Schizosaccharomyces cryophilus41.287e-50 174
LLPS-Miv-0999Microbotryum violaceum41.23e-52 181
LLPS-Dos-0912Dothistroma septosporum41.22e-44 160
LLPS-Kop-0859Komagataella pastoris41.146e-44 158
LLPS-Pyt-0976Pyrenophora teres40.989e-42 153
LLPS-Gag-0826Gaeumannomyces graminis40.964e-33 130
LLPS-Asg-1046Ashbya gossypii40.871e-0859.7
LLPS-Pytr-1545Pyrenophora triticirepentis40.587e-41 150
LLPS-Zyt-1143Zymoseptoria tritici40.332e-41 152
LLPS-Mao-0641Magnaporthe oryzae40.272e-39 147
LLPS-Map-1169Magnaporthe poae40.119e-2399.0
LLPS-Asni-1604Aspergillus niger40.071e-38 145
LLPS-Sac-0010Saccharomyces cerevisiae40.071e-45 163
LLPS-Fus-1090Fusarium solani40.04e-0858.2
LLPS-Fuv-0156Fusarium verticillioides39.947e-39 145
LLPS-Scs-0550Sclerotinia sclerotiorum39.942e-42 155
LLPS-Cogr-0193Colletotrichum graminicola39.732e-39 147
LLPS-Phn-1113Phaeosphaeria nodorum39.726e-1783.6
LLPS-Asc-1136Aspergillus clavatus39.671e-39 147
LLPS-Fuo-0385Fusarium oxysporum39.611e-38 145
LLPS-Ved-0856Verticillium dahliae39.593e-37 141
LLPS-Coo-0911Colletotrichum orbiculare39.391e-37 142
LLPS-Nef-0946Neosartorya fischeri39.335e-38 143
LLPS-Cym-0972Cyanidioschyzon merolae39.022e-1167.4
LLPS-Ast-0523Aspergillus terreus39.07e-37 140
LLPS-Asf-0737Aspergillus flavus38.876e-38 143
LLPS-Asn-1294Aspergillus nidulans38.822e-39 147
LLPS-Asfu-1326Aspergillus fumigatus37.321e-0756.6
LLPS-Aso-1161Aspergillus oryzae37.141e-33 131
LLPS-Cog-1246Colletotrichum gloeosporioides35.817e-34 132
LLPS-Usm-1286Ustilago maydis35.532e-36 139
LLPS-Spr-1140Sporisorium reilianum34.962e-36 139