LLPS-Amt-1710
AMTR_s00037p00018100
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Deoxyhypusine hydroxylase |
| Gene Name: | AMTR_s00037p00018100 |
| Ensembl Gene: | AMTR_s00037p00018100 |
| Ensembl Protein: | ERN17293 |
| Organism: | Amborella trichopoda |
| Taxa ID: | 13333 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ERN17293 | ERN17293 |
| UniProt | U5DA73, U5DA73_AMBTC | |
| GeneBank | KI392350 | ERN17293.1 |
| RefSeq | XM_006855764.2 | XP_006855826.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MASGSYFEAP QATVKFLCDR LLDKSQPISE RFRALFSLRN LQGPAPRDAL ILATRDESNL 60 61 LAHEAAFALG QMQDAEAVPA LEKILEDYSL HPIVRHEAAE ALGAIGLESN IPTLKRSLLE 120 121 DPAQEVRETC ELALRRIDEQ KCVNNIDEIS TEMKSPFLSV DPAAPASFSS SIDQLREVLL 180 181 NERNGMYERY GALFALRNLG VDRAVDAIIA SLIAGSALLR HEVAYVLGQL QDKAASAALS 240 241 DILRNSCEHP MVRHEAAEAL GSIADHDSIS LLEEFKADSE PIVSQSCEVA LSMLEYEQSG 300 301 KSFEYFFMEA PEVHQIINEA 320 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGTCTG GTAGTTACTT TGAAGCACCT CAGGCGACTG TGAAATTTCT CTGCGATCGA 60 61 TTGCTTGACA AAAGCCAGCC CATCTCCGAA CGTTTTAGGG CACTCTTTTC CCTTCGGAAC 120 121 CTCCAAGGCC CTGCCCCTCG TGATGCCCTT ATTCTTGCCA CAAGAGATGA ATCAAATTTA 180 181 CTGGCACACG AGGCAGCATT TGCATTGGGT CAAATGCAAG ATGCAGAGGC AGTTCCTGCT 240 241 CTGGAGAAGA TCCTAGAGGA TTATTCTCTC CATCCCATAG TACGCCATGA GGCAGCTGAA 300 301 GCTCTTGGAG CTATTGGGTT GGAGAGTAAC ATTCCTACAC TGAAGAGAAG TTTGCTTGAG 360 361 GATCCTGCAC AGGAGGTGCG AGAAACATGT GAGCTAGCTC TTAGACGTAT TGATGAACAG 420 421 AAATGTGTCA ATAACATTGA TGAAATCTCT ACAGAAATGA AGTCACCTTT TCTATCAGTT 480 481 GATCCTGCGG CACCTGCTTC ATTTAGCTCA TCTATTGATC AATTAAGGGA AGTTCTTCTG 540 541 AATGAAAGAA ACGGCATGTA TGAGCGCTAT GGAGCATTGT TTGCACTCCG TAATCTTGGA 600 601 GTAGATAGGG CAGTCGATGC TATTATTGCA TCCTTAATTG CTGGAAGTGC TCTCTTGCGG 660 661 CATGAGGTTG CATATGTATT GGGTCAACTA CAAGATAAAG CTGCTTCTGC CGCACTCTCA 720 721 GACATACTTA GGAATTCTTG TGAGCACCCA ATGGTTAGAC ATGAAGCTGC TGAAGCTCTG 780 781 GGTTCCATTG CAGACCATGA CAGCATCTCA CTTCTTGAGG AATTTAAAGC AGACTCTGAA 840 841 CCTATTGTTT CTCAAAGTTG TGAAGTTGCG CTAAGTATGC TCGAGTATGA ACAGTCTGGC 900 901 AAGTCCTTTG AGTATTTCTT CATGGAAGCG CCAGAAGTTC ATCAGATCAT AAATGAAGCT 960 961 TGA 963 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Molecular Function | Deoxyhypusine monooxygenase activity | |
Molecular Function | Metal ion binding | |
Biological Process | Peptidyl-lysine modification to peptidyl-hypusine |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Gor-1624 | Gossypium raimondii | 78.0 | 1e-142 | 412 |
| LLPS-Viv-0362 | Vitis vinifera | 77.92 | 1e-148 | 428 |
| LLPS-Thc-1922 | Theobroma cacao | 77.67 | 2e-145 | 419 |
| LLPS-Coc-1321 | Corchorus capsularis | 77.25 | 8e-110 | 328 |
| LLPS-Pot-1812 | Populus trichocarpa | 76.17 | 9e-140 | 405 |
| LLPS-Via-0380 | Vigna angularis | 75.17 | 1e-130 | 385 |
| LLPS-Mae-2114 | Manihot esculenta | 74.76 | 2e-138 | 402 |
| LLPS-Brn-2832 | Brassica napus | 74.75 | 2e-132 | 387 |
| LLPS-Glm-0788 | Glycine max | 74.33 | 2e-138 | 401 |
| LLPS-Phv-1843 | Phaseolus vulgaris | 74.33 | 2e-138 | 402 |
| LLPS-Cus-1496 | Cucumis sativus | 73.87 | 3e-130 | 381 |
| LLPS-Hea-2717 | Helianthus annuus | 73.72 | 1e-137 | 400 |
| LLPS-Art-2368 | Arabidopsis thaliana | 73.67 | 9e-139 | 403 |
| LLPS-Arl-2071 | Arabidopsis lyrata | 73.0 | 2e-138 | 402 |
| LLPS-Prp-2536 | Prunus persica | 72.84 | 5e-139 | 404 |
| LLPS-Met-1212 | Medicago truncatula | 72.67 | 5e-134 | 391 |
| LLPS-Tru-1140 | Triticum urartu | 72.24 | 6e-108 | 324 |
| LLPS-Brr-0673 | Brassica rapa | 72.12 | 3e-107 | 321 |
| LLPS-Nia-1663 | Nicotiana attenuata | 72.12 | 7e-136 | 396 |
| LLPS-Bro-0578 | Brassica oleracea | 72.11 | 3e-121 | 360 |
| LLPS-Orgl-2222 | Oryza glumaepatula | 72.04 | 5e-126 | 370 |
| LLPS-Mua-2263 | Musa acuminata | 71.97 | 1e-107 | 322 |
| LLPS-Sot-1193 | Solanum tuberosum | 71.79 | 9e-133 | 388 |
| LLPS-Orb-1015 | Oryza barthii | 71.71 | 9e-126 | 370 |
| LLPS-Orni-0231 | Oryza nivara | 71.71 | 9e-126 | 370 |
| LLPS-Orr-0156 | Oryza rufipogon | 71.71 | 1e-125 | 369 |
| LLPS-Sol-1289 | Solanum lycopersicum | 71.47 | 4e-133 | 389 |
| LLPS-Sei-2442 | Setaria italica | 71.02 | 6e-135 | 393 |
| LLPS-Sob-2544 | Sorghum bicolor | 71.02 | 9e-136 | 395 |
| LLPS-Hov-1710 | Hordeum vulgare | 71.01 | 3e-112 | 336 |
| LLPS-Tra-0284 | Triticum aestivum | 70.87 | 7e-132 | 385 |
| LLPS-Orm-1967 | Oryza meridionalis | 70.72 | 2e-123 | 364 |
| LLPS-Dac-2119 | Daucus carota | 70.51 | 1e-129 | 379 |
| LLPS-Org-1931 | Oryza glaberrima | 70.48 | 3e-130 | 381 |
| LLPS-Ors-0172 | Oryza sativa | 70.48 | 4e-130 | 381 |
| LLPS-Lep-0972 | Leersia perrieri | 70.16 | 6e-130 | 380 |
| LLPS-Ori-1777 | Oryza indica | 70.16 | 1e-129 | 380 |
| LLPS-Brd-2385 | Brachypodium distachyon | 69.43 | 4e-132 | 386 |
| LLPS-Orp-1278 | Oryza punctata | 68.79 | 7e-128 | 375 |
| LLPS-Orbr-2206 | Oryza brachyantha | 67.51 | 7e-126 | 371 |
| LLPS-Zem-0605 | Zea mays | 65.96 | 2e-128 | 377 |
| LLPS-Sem-1163 | Selaginella moellendorffii | 60.54 | 4e-94 | 288 |
| LLPS-Vir-0999 | Vigna radiata | 60.2 | 2e-99 | 306 |
| LLPS-Php-1338 | Physcomitrella patens | 59.59 | 2e-85 | 267 |
| LLPS-Fia-2282 | Ficedula albicollis | 52.28 | 1e-71 | 231 |
| LLPS-Gaga-1688 | Gallus gallus | 51.75 | 1e-68 | 223 |
| LLPS-Meg-2183 | Meleagris gallopavo | 50.53 | 2e-65 | 214 |
| LLPS-Chr-0469 | Chlamydomonas reinhardtii | 50.49 | 1e-72 | 234 |
| LLPS-Xim-2008 | Xiphophorus maculatus | 50.0 | 1e-64 | 213 |
| LLPS-Leo-0358 | Lepisosteus oculatus | 49.82 | 2e-62 | 207 |
| LLPS-Nol-4183 | Nomascus leucogenys | 49.19 | 5e-39 | 144 |
| LLPS-Orn-3580 | Oreochromis niloticus | 49.13 | 2e-67 | 220 |
| LLPS-Orl-3320 | Oryzias latipes | 49.12 | 2e-66 | 217 |
| LLPS-Sah-1918 | Sarcophilus harrisii | 48.97 | 3e-64 | 211 |
| LLPS-Asm-1102 | Astyanax mexicanus | 48.78 | 7e-64 | 211 |
| LLPS-Aon-2867 | Aotus nancymaae | 48.77 | 8e-61 | 202 |
| LLPS-Icp-3389 | Ictalurus punctatus | 48.77 | 2e-63 | 209 |
| LLPS-Gaa-0939 | Gasterosteus aculeatus | 48.61 | 5e-66 | 216 |
| LLPS-Lac-3935 | Latimeria chalumnae | 48.48 | 1e-66 | 218 |
| LLPS-Cap-1607 | Cavia porcellus | 48.47 | 2e-62 | 207 |
| LLPS-Sus-4312 | Sus scrofa | 48.43 | 3e-61 | 204 |
| LLPS-Tar-3610 | Takifugu rubripes | 48.42 | 1e-67 | 221 |
| LLPS-Maf-1324 | Macaca fascicularis | 48.42 | 5e-62 | 206 |
| LLPS-Scf-1863 | Scleropages formosus | 48.25 | 6e-63 | 208 |
| LLPS-Dio-4371 | Dipodomys ordii | 48.19 | 2e-17 | 81.3 |
| LLPS-Ran-3876 | Rattus norvegicus | 48.14 | 3e-64 | 211 |
| LLPS-Mum-4784 | Mus musculus | 48.14 | 3e-62 | 206 |
| LLPS-Pap-3339 | Pan paniscus | 48.07 | 2e-60 | 201 |
| LLPS-Poa-1684 | Pongo abelii | 47.95 | 3e-63 | 209 |
| LLPS-Otg-1465 | Otolemur garnettii | 47.9 | 2e-59 | 199 |
| LLPS-Ict-1446 | Ictidomys tridecemlineatus | 47.89 | 7e-59 | 197 |
| LLPS-Caf-3188 | Canis familiaris | 47.8 | 3e-62 | 206 |
| LLPS-Fec-4605 | Felis catus | 47.74 | 2e-61 | 204 |
| LLPS-Ten-2886 | Tetraodon nigroviridis | 47.72 | 6e-63 | 208 |
| LLPS-Dar-0792 | Danio rerio | 47.72 | 1e-62 | 207 |
| LLPS-Paa-2980 | Papio anubis | 47.6 | 5e-62 | 206 |
| LLPS-Cea-4603 | Cercocebus atys | 47.6 | 2e-61 | 205 |
| LLPS-Hos-2918 | Homo sapiens | 47.6 | 9e-62 | 205 |
| LLPS-Man-4223 | Macaca nemestrina | 47.6 | 4e-62 | 206 |
| LLPS-Mup-1252 | Mustela putorius furo | 47.26 | 3e-61 | 204 |
| LLPS-Chs-4821 | Chlorocebus sabaeus | 47.26 | 5e-61 | 204 |
| LLPS-Pat-4074 | Pan troglodytes | 47.26 | 2e-61 | 204 |
| LLPS-Pes-1615 | Pelodiscus sinensis | 47.11 | 2e-13 | 73.2 |
| LLPS-Eqc-4804 | Equus caballus | 47.02 | 8e-54 | 185 |
| LLPS-Urm-1057 | Ursus maritimus | 46.99 | 1e-15 | 79.3 |
| LLPS-Ora-2820 | Ornithorhynchus anatinus | 46.98 | 3e-44 | 158 |
| LLPS-Bot-0260 | Bos taurus | 46.92 | 2e-61 | 204 |
| LLPS-Aim-2966 | Ailuropoda melanoleuca | 46.78 | 7e-60 | 200 |
| LLPS-Fud-3973 | Fukomys damarensis | 46.62 | 7e-24 | 100 |
| LLPS-Cym-0972 | Cyanidioschyzon merolae | 46.55 | 3e-11 | 67.4 |
| LLPS-Abg-1750 | Absidia glauca | 46.52 | 2e-51 | 188 |
| LLPS-Mea-3583 | Mesocricetus auratus | 46.23 | 2e-56 | 191 |
| LLPS-Mod-1035 | Monodelphis domestica | 46.15 | 3e-43 | 158 |
| LLPS-Cae-1749 | Caenorhabditis elegans | 45.71 | 2e-24 | 105 |
| LLPS-Loa-0691 | Loxodonta africana | 45.45 | 3e-34 | 130 |
| LLPS-Caj-3953 | Callithrix jacchus | 45.24 | 9e-11 | 66.2 |
| LLPS-Yal-0539 | Yarrowia lipolytica | 44.35 | 3e-13 | 73.2 |
| LLPS-Gog-3515 | Gorilla gorilla | 44.13 | 5e-38 | 141 |
| LLPS-Cis-1492 | Ciona savignyi | 43.94 | 3e-51 | 177 |
| LLPS-Drm-0620 | Drosophila melanogaster | 43.39 | 4e-60 | 201 |
| LLPS-Cii-1023 | Ciona intestinalis | 43.29 | 1e-53 | 184 |
| LLPS-Scj-0357 | Schizosaccharomyces japonicus | 42.86 | 2e-14 | 77.0 |
| LLPS-Ova-0176 | Ovis aries | 42.86 | 4e-44 | 158 |
| LLPS-Mel-1098 | Melampsora laricipopulina | 42.86 | 2e-52 | 181 |
| LLPS-Pof-4197 | Poecilia formosa | 42.74 | 6e-22 | 96.7 |
| LLPS-Miv-0999 | Microbotryum violaceum | 42.62 | 2e-51 | 179 |
| LLPS-Tum-0081 | Tuber melanosporum | 42.47 | 3e-48 | 170 |
| LLPS-Chc-0809 | Chondrus crispus | 42.25 | 6e-44 | 160 |
| LLPS-Scc-0003 | Schizosaccharomyces cryophilus | 42.16 | 5e-50 | 175 |
| LLPS-Pug-0037 | Puccinia graminis | 42.06 | 5e-09 | 60.8 |
| LLPS-Xet-0999 | Xenopus tropicalis | 41.81 | 2e-45 | 162 |
| LLPS-Osl-1433 | Ostreococcus lucimarinus | 41.5 | 5e-43 | 156 |
| LLPS-Scp-1140 | Schizosaccharomyces pombe | 41.48 | 5e-52 | 180 |
| LLPS-Put-1257 | Puccinia triticina | 41.43 | 1e-17 | 85.5 |
| LLPS-Crn-1049 | Cryptococcus neoformans | 40.78 | 8e-42 | 154 |
| LLPS-Trr-1483 | Trichoderma reesei | 40.71 | 2e-17 | 85.1 |
| LLPS-Map-1169 | Magnaporthe poae | 40.62 | 2e-11 | 66.6 |
| LLPS-Trv-0317 | Trichoderma virens | 40.56 | 3e-39 | 146 |
| LLPS-Pyt-0976 | Pyrenophora teres | 40.51 | 3e-40 | 149 |
| LLPS-Phn-1113 | Phaeosphaeria nodorum | 40.46 | 2e-38 | 144 |
| LLPS-Dos-0912 | Dothistroma septosporum | 40.44 | 4e-41 | 151 |
| LLPS-Nec-0510 | Neurospora crassa | 40.43 | 2e-39 | 147 |
| LLPS-Nef-0946 | Neosartorya fischeri | 40.19 | 2e-39 | 147 |
| LLPS-Pytr-1545 | Pyrenophora triticirepentis | 40.13 | 4e-40 | 149 |
| LLPS-Asc-1136 | Aspergillus clavatus | 40.12 | 2e-40 | 150 |
| LLPS-Gas-0657 | Galdieria sulphuraria | 40.07 | 8e-45 | 160 |
| LLPS-Asni-1604 | Aspergillus niger | 40.06 | 5e-39 | 146 |
| LLPS-Scs-0550 | Sclerotinia sclerotiorum | 40.0 | 2e-15 | 79.7 |
| LLPS-Beb-1196 | Beauveria bassiana | 39.88 | 2e-36 | 139 |
| LLPS-Coo-0911 | Colletotrichum orbiculare | 39.81 | 9e-38 | 143 |
| LLPS-Asf-0737 | Aspergillus flavus | 39.56 | 3e-39 | 147 |
| LLPS-Ast-0523 | Aspergillus terreus | 39.51 | 3e-38 | 144 |
| LLPS-Mal-1632 | Mandrillus leucophaeus | 39.38 | 3e-36 | 137 |
| LLPS-Ved-0856 | Verticillium dahliae | 39.26 | 2e-08 | 59.3 |
| LLPS-Cog-1246 | Colletotrichum gloeosporioides | 39.26 | 4e-07 | 55.1 |
| LLPS-Zyt-1143 | Zymoseptoria tritici | 39.17 | 1e-38 | 145 |
| LLPS-Asg-1046 | Ashbya gossypii | 39.07 | 5e-43 | 156 |
| LLPS-Cogr-0193 | Colletotrichum graminicola | 38.99 | 7e-37 | 140 |
| LLPS-Fuv-0156 | Fusarium verticillioides | 38.93 | 4e-10 | 64.3 |
| LLPS-Asn-1294 | Aspergillus nidulans | 38.56 | 4e-38 | 144 |
| LLPS-Kop-0859 | Komagataella pastoris | 38.41 | 2e-41 | 152 |
| LLPS-Gag-0826 | Gaeumannomyces graminis | 38.39 | 8e-29 | 118 |
| LLPS-Mao-0641 | Magnaporthe oryzae | 38.36 | 7e-36 | 137 |
| LLPS-Lem-0395 | Leptosphaeria maculans | 38.29 | 1e-37 | 142 |
| LLPS-Blg-1515 | Blumeria graminis | 38.23 | 7e-41 | 151 |
| LLPS-Sac-0010 | Saccharomyces cerevisiae | 38.19 | 1e-45 | 163 |
| LLPS-Fuo-0385 | Fusarium oxysporum | 38.17 | 2e-09 | 62.4 |
| LLPS-Rhb-2066 | Rhinopithecus bieti | 37.54 | 9e-36 | 135 |
| LLPS-Aso-1161 | Aspergillus oryzae | 37.12 | 1e-34 | 134 |
| LLPS-Asfu-1326 | Aspergillus fumigatus | 36.76 | 2e-35 | 137 |
| LLPS-Fus-1090 | Fusarium solani | 36.31 | 7e-32 | 126 |
| LLPS-Spr-1140 | Sporisorium reilianum | 34.65 | 1e-32 | 129 |
| LLPS-Usm-1286 | Ustilago maydis | 34.37 | 3e-33 | 131 |