• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Via-1074
LR48_Vigan598s000100

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Lactoylglutathione lyase; Glyoxalase I
Gene Name: LR48_Vigan598s000100
Ensembl Gene: LR48_Vigan598s000100
Ensembl Protein: KOM28840
Organism: Vigna angularis
Taxa ID: 3914
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblKOM28840KOM28840
UniProtA0A0L9TDZ8, A0A0L9TDZ8_PHAAN
GeneBankKQ258454KOM28840.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MASGPKESPA  NNPGLHTTPD  EATKGYIMQQ  TMFRIKDPEV  SLDFYSRVLG  MSLLKRLDFV  60
61    DMKFSLYFLG  YEDTSKAPSN  PVDKTVWTFS  QKATIELTHN  WGTESDPEFK  GYHNGNSEPR  120
121   GFGHIGITVD  DTVKACERFQ  NLGVEFVKKP  DEAPSDAAAN  LSHQLCIHDR  LNSSSAVVRA  180
181   PTHCSALSQS  HHCHHPNTSR  VLKPPWSCRM  HYGTLYWWST  ERTIVQYHEK  KNYRE  235
Nucleotide CDS Sequence (FASTA)
1     ATGGCTTCGG  GACCCAAGGA  ATCGCCCGCC  AACAACCCCG  GTCTGCATAC  AACTCCGGAC  60
61    GAAGCTACCA  AGGGTTACAT  TATGCAGCAA  ACTATGTTTC  GAATCAAGGA  CCCCGAAGTG  120
121   AGCCTTGATT  TCTATTCTCG  CGTCTTGGGC  ATGTCTTTGC  TTAAGAGGCT  GGATTTTGTG  180
181   GACATGAAGT  TCAGCCTGTA  TTTTTTGGGC  TATGAGGATA  CGTCAAAAGC  TCCGAGTAAT  240
241   CCAGTTGATA  AAACAGTTTG  GACCTTTTCC  CAGAAGGCTA  CAATTGAACT  GACACATAAT  300
301   TGGGGTACCG  AAAGTGATCC  AGAGTTCAAA  GGATACCACA  ATGGAAATTC  TGAACCTCGC  360
361   GGCTTTGGAC  ACATTGGCAT  AACTGTTGAT  GACACAGTAA  AGGCATGTGA  AAGATTTCAG  420
421   AATCTGGGAG  TTGAGTTTGT  TAAGAAACCA  GATGAAGCAC  CTTCAGATGC  TGCTGCGAAT  480
481   CTTTCCCACC  AGCTTTGTAT  CCATGATCGT  CTGAACTCTT  CTAGTGCTGT  TGTTCGTGCA  540
541   CCAACACACT  GTTCTGCTCT  GTCTCAGAGT  CATCATTGTC  ATCACCCCAA  CACTTCCCGT  600
601   GTTTTGAAGC  CACCTTGGAG  TTGCCGGATG  CATTATGGGA  CCCTTTATTG  GTGGAGCACA  660
661   GAAAGAACAA  TTGTACAGTA  TCACGAAAAG  AAAAACTACA  GAGAATAA  708

▼ KEYWORD

ID
Family
Complete proteome
Lyase
Metal-binding
Reference proteome
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Cytosol
Molecular Function
Lactoylglutathione lyase activity
Molecular Function
Metal ion binding
Biological Process
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
Biological Process
Response to cadmium ion

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Phv-0837Phaseolus vulgaris91.824e-105 310
LLPS-Prp-0580Prunus persica86.275e-96 287
LLPS-Viv-0682Vitis vinifera84.971e-94 284
LLPS-Coc-2209Corchorus capsularis83.895e-90 272
LLPS-Mua-1809Musa acuminata83.553e-92 278
LLPS-Cus-0592Cucumis sativus82.397e-96 285
LLPS-Mae-1128Manihot esculenta82.357e-92 276
LLPS-Nia-1025Nicotiana attenuata82.02e-90 273
LLPS-Amt-0077Amborella trichopoda81.71e-89 272
LLPS-Brr-1535Brassica rapa81.71e-89 271
LLPS-Art-2822Arabidopsis thaliana81.73e-83 255
LLPS-Brn-3005Brassica napus81.71e-89 271
LLPS-Sot-2108Solanum tuberosum81.335e-90 272
LLPS-Sol-0996Solanum lycopersicum81.334e-90 271
LLPS-Pot-1040Populus trichocarpa81.134e-90 273
LLPS-Arl-2268Arabidopsis lyrata81.051e-88 268
LLPS-Tru-1859Triticum urartu80.924e-90 271
LLPS-Tra-1288Triticum aestivum80.921e-90 274
LLPS-Hov-1189Hordeum vulgare80.292e-79 243
LLPS-Brd-1999Brachypodium distachyon80.264e-89 270
LLPS-Met-0621Medicago truncatula79.773e-96 288
LLPS-Glm-0871Glycine max78.927e-102 302
LLPS-Sob-2286Sorghum bicolor78.151e-85 261
LLPS-Orbr-2286Oryza brachyantha77.921e-87 266
LLPS-Gor-0287Gossypium raimondii77.852e-85 260
LLPS-Bro-0741Brassica oleracea77.783e-2293.6
LLPS-Org-1316Oryza glaberrima77.632e-85 261
LLPS-Orb-1541Oryza barthii77.632e-85 261
LLPS-Orr-1722Oryza rufipogon77.274e-86 262
LLPS-Ors-1996Oryza sativa77.274e-86 262
LLPS-Orp-0625Oryza punctata77.278e-86 262
LLPS-Ori-1531Oryza indica77.274e-86 262
LLPS-Zem-1916Zea mays76.975e-85 259
LLPS-Hea-1598Helianthus annuus75.973e-79 245
LLPS-Thc-0130Theobroma cacao75.956e-87 265
LLPS-Sem-2433Selaginella moellendorffii75.689e-84 254
LLPS-Lep-2195Leersia perrieri74.382e-84 258
LLPS-Sei-1288Setaria italica72.666e-66 207
LLPS-Vir-0363Vigna radiata71.227e-60 193
LLPS-Orm-0930Oryza meridionalis68.674e-68 220
LLPS-Orgl-2175Oryza glumaepatula68.673e-67 218
LLPS-Php-0448Physcomitrella patens68.215e-72 227
LLPS-Mum-4739Mus musculus65.932e-60 195
LLPS-Cap-4665Cavia porcellus65.676e-59 191
LLPS-Mea-3048Mesocricetus auratus64.962e-60 194
LLPS-Dio-2781Dipodomys ordii64.935e-58 189
LLPS-Fud-2712Fukomys damarensis64.181e-57 187
LLPS-Orni-2134Oryza nivara64.123e-70 222
LLPS-Chr-0540Chlamydomonas reinhardtii63.959e-67 212
LLPS-Anc-2316Anolis carolinensis63.838e-60 193
LLPS-Gaga-0008Gallus gallus63.644e-61 196
LLPS-Ten-1745Tetraodon nigroviridis63.643e-55 181
LLPS-Fia-1823Ficedula albicollis63.572e-60 195
LLPS-Ran-0738Rattus norvegicus63.53e-60 194
LLPS-Cas-3737Carlito syrichta63.431e-56 185
LLPS-Tag-3470Taeniopygia guttata63.437e-57 185
LLPS-Icp-1545Ictalurus punctatus63.363e-56 184
LLPS-Asm-2928Astyanax mexicanus63.362e-56 184
LLPS-Myl-1904Myotis lucifugus62.862e-58 190
LLPS-Ict-3114Ictidomys tridecemlineatus62.774e-58 189
LLPS-Sus-1172Sus scrofa62.779e-58 188
LLPS-Otg-4129Otolemur garnettii62.636e-37 134
LLPS-Scf-1933Scleropages formosus62.69e-56 182
LLPS-Mod-2383Monodelphis domestica62.242e-59 192
LLPS-Ora-0982Ornithorhynchus anatinus62.143e-59 192
LLPS-Eqc-4768Equus caballus62.049e-58 188
LLPS-Caf-2015Canis familiaris62.041e-57 187
LLPS-Ova-1773Ovis aries62.043e-57 186
LLPS-Bot-4271Bos taurus62.041e-57 187
LLPS-Poa-4516Pongo abelii61.945e-56 183
LLPS-Mam-3790Macaca mulatta61.947e-56 183
LLPS-Hos-0358Homo sapiens61.941e-55 182
LLPS-Pap-4311Pan paniscus61.946e-56 183
LLPS-Pat-4298Pan troglodytes61.946e-56 183
LLPS-Man-0269Macaca nemestrina61.947e-56 183
LLPS-Mal-1770Mandrillus leucophaeus61.947e-56 183
LLPS-Paa-4159Papio anubis61.947e-56 183
LLPS-Gog-2348Gorilla gorilla61.946e-56 183
LLPS-Caj-1080Callithrix jacchus61.946e-56 183
LLPS-Chs-4347Chlorocebus sabaeus61.947e-56 183
LLPS-Maf-0196Macaca fascicularis61.947e-56 183
LLPS-Cea-4504Cercocebus atys61.947e-56 183
LLPS-Aim-3079Ailuropoda melanoleuca61.432e-57 187
LLPS-Tut-1443Tursiops truncatus61.432e-57 187
LLPS-Nol-2630Nomascus leucogenys61.192e-54 179
LLPS-Orn-4121Oreochromis niloticus61.192e-55 181
LLPS-Drm-1633Drosophila melanogaster61.152e-56 184
LLPS-Sah-2654Sarcophilus harrisii61.115e-57 186
LLPS-Anp-1745Anas platyrhynchos60.966e-60 193
LLPS-Mup-3776Mustela putorius furo60.715e-57 186
LLPS-Leo-2641Lepisosteus oculatus60.584e-55 181
LLPS-Pof-4166Poecilia formosa60.458e-56 183
LLPS-Urm-2102Ursus maritimus60.272e-58 191
LLPS-Pes-1006Pelodiscus sinensis60.141e-58 190
LLPS-Scm-2017Scophthalmus maximus60.09e-56 184
LLPS-Loa-4185Loxodonta africana60.01e-54 180
LLPS-Dar-1004Danio rerio59.851e-55 182
LLPS-Orl-1531Oryzias latipes59.852e-54 179
LLPS-Aon-3560Aotus nancymaae59.717e-55 180
LLPS-Tar-3284Takifugu rubripes59.592e-56 184
LLPS-Gaa-3828Gasterosteus aculeatus58.572e-54 179
LLPS-Lac-2510Latimeria chalumnae58.226e-58 188
LLPS-Xim-4081Xiphophorus maculatus58.215e-53 176
LLPS-Cii-1894Ciona intestinalis57.865e-52 173
LLPS-Fec-2587Felis catus57.536e-56 183
LLPS-Xet-3197Xenopus tropicalis50.721e-39 141
LLPS-Spr-0413Sporisorium reilianum50.392e-33 124
LLPS-Rhb-3539Rhinopithecus bieti49.251e-32 122
LLPS-Fuo-1213Fusarium oxysporum49.223e-29 117
LLPS-Fuv-0944Fusarium verticillioides49.223e-29 117
LLPS-Crn-1562Cryptococcus neoformans48.878e-31 118
LLPS-Mel-1260Melampsora laricipopulina48.781e-29 113
LLPS-Fus-1390Fusarium solani48.443e-28 114
LLPS-Nec-0394Neurospora crassa48.447e-27 110
LLPS-Coo-0397Colletotrichum orbiculare48.442e-27 112
LLPS-Trv-1093Trichoderma virens48.391e-28 115
LLPS-Sac-1224Saccharomyces cerevisiae48.337e-27 110
LLPS-Usm-1089Ustilago maydis48.035e-32 120
LLPS-Gas-0869Galdieria sulphuraria48.033e-28 114
LLPS-Beb-0747Beauveria bassiana47.581e-26 109
LLPS-Miv-1391Microbotryum violaceum47.293e-29 113
LLPS-Gag-0878Gaeumannomyces graminis47.241e-23 101
LLPS-Lem-0098Leptosphaeria maculans47.22e-24 103
LLPS-Ast-0911Aspergillus terreus47.152e-25 105
LLPS-Pytr-0537Pyrenophora triticirepentis46.883e-27 111
LLPS-Cog-0734Colletotrichum gloeosporioides46.885e-25 105
LLPS-Asf-0357Aspergillus flavus46.889e-27 110
LLPS-Aso-0769Aspergillus oryzae46.889e-27 110
LLPS-Scs-1004Sclerotinia sclerotiorum46.513e-28 113
LLPS-Zyt-0449Zymoseptoria tritici46.099e-25 104
LLPS-Pyt-0917Pyrenophora teres46.095e-26 108
LLPS-Yal-1256Yarrowia lipolytica46.092e-30 120
LLPS-Asc-1449Aspergillus clavatus45.742e-25 106
LLPS-Phn-0372Phaeosphaeria nodorum45.529e-26 107
LLPS-Asfu-0337Aspergillus fumigatus45.451e-26 110
LLPS-Nef-1612Neosartorya fischeri45.454e-27 111
LLPS-Asn-1450Aspergillus nidulans45.454e-27 111
LLPS-Trr-1230Trichoderma reesei45.387e-25 104
LLPS-Abg-1171Absidia glauca45.193e-29 120
LLPS-Kop-1117Komagataella pastoris45.114e-28 114
LLPS-Mao-1130Magnaporthe oryzae45.111e-24 104
LLPS-Cym-0914Cyanidioschyzon merolae44.975e-30 116
LLPS-Dos-0455Dothistroma septosporum44.533e-24 103
LLPS-Map-1034Magnaporthe poae44.531e-2298.6
LLPS-Ved-1094Verticillium dahliae44.353e-24 102
LLPS-Tum-1505Tuber melanosporum44.356e-25 104
LLPS-Asg-0377Ashbya gossypii44.344e-2297.1
LLPS-Cogr-0119Colletotrichum graminicola44.122e-24 103
LLPS-Put-0843Puccinia triticina43.77e-32 120
LLPS-Asni-1490Aspergillus niger43.72e-2297.8
LLPS-Scj-1140Schizosaccharomyces japonicus43.336e-1987.4
LLPS-Scc-0327Schizosaccharomyces cryophilus42.191e-1989.7
LLPS-Pug-1137Puccinia graminis42.03e-33 127
LLPS-Scp-1252Schizosaccharomyces pombe41.183e-1988.6
LLPS-Chc-0755Chondrus crispus35.712e-1579.3
LLPS-Dac-0240Daucus carota30.899e-0958.5