• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Sol-0996
GLX1

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Lactoylglutathione lyase; Aldoketomutase; Glyoxalase I; Glx I; Ketone-aldehyde mutase; Methylglyoxalase; S-D-lactoylglutathione methylglyoxal lyase
Gene Name: GLX1
Ensembl Gene: Solyc11g069040.3
Ensembl Protein: Solyc11g069040.3.1
Organism: Solanum lycopersicum
Taxa ID: 4081
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION


Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MASESKDSPS  NNPGLHATPD  EATKGYFLQQ  TMFRIKDPKV  SLEFYSKVLG  MSLLKRLDFP  60
61    EMKFSLYFMG  YEDTASAPSD  PVERTAWTFS  QKSTLELTHN  WGTESDPNFT  GYHNGNSEPR  120
121   GFGHIGVTVD  DVYKACERFE  SLGVEFVKKP  LDGKMKGIAF  IKDPDGYWIE  IFDTKIIKDA  180
181   AGSAS  185
Nucleotide CDS Sequence (FASTA)
1     ATGGCTTCAG  AGTCGAAGGA  TTCGCCTTCT  AACAATCCAG  GTCTTCATGC  TACCCCTGAT  60
61    GAAGCAACTA  AAGGTTACTT  TTTGCAGCAA  ACTATGTTTA  GAATCAAGGA  TCCCAAAGTG  120
121   AGTCTTGAAT  TCTACTCCAA  AGTGTTGGGC  ATGTCCTTGC  TCAAGAGATT  GGATTTCCCT  180
181   GAGATGAAGT  TCAGCTTATA  CTTCATGGGG  TATGAGGATA  CAGCATCAGC  TCCCAGTGAT  240
241   CCCGTTGAAC  GTACTGCTTG  GACCTTTAGT  CAGAAATCTA  CATTAGAGCT  TACACACAAC  300
301   TGGGGTACTG  AGAGTGACCC  TAATTTTACA  GGTTACCACA  ATGGAAATTC  AGAACCACGT  360
361   GGCTTTGGAC  ACATAGGTGT  TACTGTTGAT  GATGTCTACA  AGGCTTGTGA  GAGATTTGAA  420
421   AGTCTGGGAG  TAGAGTTTGT  AAAGAAACCT  CTTGACGGAA  AAATGAAAGG  TATTGCATTT  480
481   ATTAAAGATC  CTGATGGCTA  TTGGATCGAG  ATCTTTGACA  CGAAAATTAT  CAAAGACGCT  540
541   GCTGGTTCTG  CTTCTTAG  558

▼ KEYWORD


ID
Family
Complete proteome
Lyase
Metal-binding
Reference proteome
Stress response
Zinc

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Chloroplast
Cellular Component
Cytosol
Molecular Function
Lactoylglutathione lyase activity
Molecular Function
Metal ion binding
Biological Process
Methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
Biological Process
Response to cadmium ion
Biological Process
Response to salt stress
Biological Process
Response to water deprivation

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sot-2108Solanum tuberosum96.761e-132 378
LLPS-Nia-1025Nicotiana attenuata93.511e-129 371
LLPS-Coc-2209Corchorus capsularis84.971e-107 315
LLPS-Glm-0871Glycine max84.751e-113 330
LLPS-Met-0621Medicago truncatula83.78e-116 336
LLPS-Pot-1040Populus trichocarpa83.244e-111 324
LLPS-Prp-0580Prunus persica83.241e-114 333
LLPS-Viv-0682Vitis vinifera82.72e-114 332
LLPS-Phv-0837Phaseolus vulgaris82.162e-114 332
LLPS-Via-1074Vigna angularis81.333e-90 271
LLPS-Bro-0741Brassica oleracea81.131e-2395.9
LLPS-Mae-1128Manihot esculenta81.083e-112 326
LLPS-Lep-2195Leersia perrieri80.96e-106 310
LLPS-Sei-1288Setaria italica80.693e-86 258
LLPS-Orm-0930Oryza meridionalis80.524e-89 272
LLPS-Orgl-2175Oryza glumaepatula80.523e-88 270
LLPS-Sob-2286Sorghum bicolor79.534e-101 298
LLPS-Cus-0592Cucumis sativus79.461e-109 318
LLPS-Tru-1859Triticum urartu79.353e-110 320
LLPS-Mua-1809Musa acuminata79.352e-109 319
LLPS-Brd-1999Brachypodium distachyon79.356e-109 318
LLPS-Tra-1288Triticum aestivum79.357e-111 323
LLPS-Brr-1535Brassica rapa78.926e-109 318
LLPS-Brn-3005Brassica napus78.926e-109 318
LLPS-Hov-1189Hordeum vulgare78.836e-81 245
LLPS-Org-1316Oryza glaberrima78.571e-104 307
LLPS-Orb-1541Oryza barthii78.571e-104 307
LLPS-Amt-0077Amborella trichopoda78.432e-89 270
LLPS-Art-2822Arabidopsis thaliana78.382e-100 296
LLPS-Arl-2268Arabidopsis lyrata78.386e-107 313
LLPS-Zem-1916Zea mays78.093e-101 298
LLPS-Orbr-2286Oryza brachyantha77.969e-106 310
LLPS-Hea-1598Helianthus annuus77.849e-103 303
LLPS-Thc-0130Theobroma cacao77.784e-106 311
LLPS-Ors-1996Oryza sativa77.429e-105 308
LLPS-Orp-0625Oryza punctata77.428e-104 306
LLPS-Orr-1722Oryza rufipogon77.429e-105 308
LLPS-Ori-1531Oryza indica77.429e-105 308
LLPS-Gor-0287Gossypium raimondii75.542e-101 299
LLPS-Orni-2134Oryza nivara74.715e-91 273
LLPS-Php-0448Physcomitrella patens73.812e-93 279
LLPS-Sem-2433Selaginella moellendorffii73.221e-100 295
LLPS-Ran-0738Rattus norvegicus69.683e-79 241
LLPS-Tag-3470Taeniopygia guttata69.332e-75 230
LLPS-Mum-4739Mus musculus69.185e-79 240
LLPS-Fud-2712Fukomys damarensis68.831e-76 234
LLPS-Pes-1006Pelodiscus sinensis68.791e-78 239
LLPS-Cap-4665Cavia porcellus68.592e-76 233
LLPS-Mea-3048Mesocricetus auratus68.553e-78 238
LLPS-Dio-2781Dipodomys ordii68.358e-77 234
LLPS-Mod-2383Monodelphis domestica68.129e-78 237
LLPS-Ora-0982Ornithorhynchus anatinus68.122e-78 239
LLPS-Gaga-0008Gallus gallus67.922e-78 238
LLPS-Ova-1773Ovis aries67.748e-76 232
LLPS-Sah-2654Sarcophilus harrisii67.722e-74 229
LLPS-Cas-3737Carlito syrichta67.532e-74 228
LLPS-Fia-1823Ficedula albicollis67.58e-79 239
LLPS-Scf-1933Scleropages formosus67.332e-73 226
LLPS-Loa-4185Loxodonta africana67.321e-73 226
LLPS-Lac-2510Latimeria chalumnae67.32e-78 238
LLPS-Ict-3114Ictidomys tridecemlineatus67.32e-76 234
LLPS-Eqc-4768Equus caballus67.19e-75 229
LLPS-Caf-2015Canis familiaris67.11e-75 231
LLPS-Anc-2316Anolis carolinensis67.11e-76 234
LLPS-Sus-1172Sus scrofa67.12e-75 231
LLPS-Bot-4271Bos taurus67.12e-75 231
LLPS-Chr-0540Chlamydomonas reinhardtii67.067e-85 256
LLPS-Poa-4516Pongo abelii66.881e-74 229
LLPS-Tut-1443Tursiops truncatus66.882e-76 234
LLPS-Myl-1904Myotis lucifugus66.881e-76 234
LLPS-Anp-1745Anas platyrhynchos66.671e-78 239
LLPS-Leo-2641Lepisosteus oculatus66.672e-72 223
LLPS-Icp-1545Ictalurus punctatus66.676e-73 224
LLPS-Pat-4298Pan troglodytes66.235e-74 228
LLPS-Pap-4311Pan paniscus66.235e-74 228
LLPS-Hos-0358Homo sapiens66.239e-74 227
LLPS-Man-0269Macaca nemestrina66.233e-74 228
LLPS-Mam-3790Macaca mulatta66.233e-74 228
LLPS-Nol-2630Nomascus leucogenys66.232e-73 226
LLPS-Chs-4347Chlorocebus sabaeus66.232e-74 228
LLPS-Maf-0196Macaca fascicularis66.233e-74 228
LLPS-Cea-4504Cercocebus atys66.233e-74 228
LLPS-Gog-2348Gorilla gorilla66.235e-74 228
LLPS-Caj-1080Callithrix jacchus66.233e-74 228
LLPS-Mal-1770Mandrillus leucophaeus66.233e-74 228
LLPS-Paa-4159Papio anubis66.233e-74 228
LLPS-Aon-3560Aotus nancymaae66.014e-73 224
LLPS-Asm-2928Astyanax mexicanus66.04e-73 225
LLPS-Aim-3079Ailuropoda melanoleuca65.627e-76 232
LLPS-Orn-4121Oreochromis niloticus65.369e-73 224
LLPS-Otg-4129Otolemur garnettii65.325e-55 179
LLPS-Cii-1894Ciona intestinalis65.164e-71 220
LLPS-Mup-3776Mustela putorius furo65.03e-75 231
LLPS-Pof-4166Poecilia formosa64.719e-73 224
LLPS-Ten-1745Tetraodon nigroviridis64.718e-72 222
LLPS-Gaa-3828Gasterosteus aculeatus64.712e-72 223
LLPS-Dar-1004Danio rerio64.674e-72 223
LLPS-Xim-4081Xiphophorus maculatus64.054e-72 223
LLPS-Orl-1531Oryzias latipes64.01e-70 218
LLPS-Drm-1633Drosophila melanogaster63.86e-77 234
LLPS-Fec-2587Felis catus63.753e-74 228
LLPS-Scm-2017Scophthalmus maximus63.41e-70 221
LLPS-Tar-3284Takifugu rubripes62.263e-71 220
LLPS-Vir-0363Vigna radiata59.712e-51 170
LLPS-Urm-2102Ursus maritimus59.093e-60 194
LLPS-Xet-3197Xenopus tropicalis58.391e-58 188
LLPS-Nef-1612Neosartorya fischeri54.976e-47 162
LLPS-Ast-0911Aspergillus terreus54.935e-44 154
LLPS-Asc-1449Aspergillus clavatus54.733e-45 157
LLPS-Usm-1089Ustilago maydis54.614e-49 163
LLPS-Spr-0413Sporisorium reilianum54.612e-51 169
LLPS-Rhb-3539Rhinopithecus bieti54.555e-50 165
LLPS-Asfu-0337Aspergillus fumigatus54.35e-47 162
LLPS-Aso-0769Aspergillus oryzae54.34e-46 160
LLPS-Asf-0357Aspergillus flavus54.34e-46 160
LLPS-Put-0843Puccinia triticina54.111e-50 167
LLPS-Miv-1391Microbotryum violaceum51.971e-44 151
LLPS-Cym-0914Cyanidioschyzon merolae51.957e-43 148
LLPS-Crn-1562Cryptococcus neoformans51.335e-44 150
LLPS-Asni-1490Aspergillus niger50.977e-41 146
LLPS-Fuo-1213Fusarium oxysporum50.683e-42 151
LLPS-Fuv-0944Fusarium verticillioides50.683e-42 151
LLPS-Gas-0869Galdieria sulphuraria50.672e-38 140
LLPS-Trr-1230Trichoderma reesei50.357e-43 151
LLPS-Yal-1256Yarrowia lipolytica50.01e-42 151
LLPS-Asn-1450Aspergillus nidulans50.02e-45 158
LLPS-Pug-1137Puccinia graminis49.74e-51 171
LLPS-Nec-0394Neurospora crassa49.73e-44 155
LLPS-Abg-1171Absidia glauca49.695e-45 162
LLPS-Trv-1093Trichoderma virens49.358e-45 157
LLPS-Fus-1390Fusarium solani49.325e-42 149
LLPS-Gag-0878Gaeumannomyces graminis49.321e-44 156
LLPS-Scc-0327Schizosaccharomyces cryophilus49.047e-35 130
LLPS-Scj-1140Schizosaccharomyces japonicus48.994e-37 136
LLPS-Sac-1224Saccharomyces cerevisiae48.724e-39 142
LLPS-Scp-1252Schizosaccharomyces pombe48.14e-33 125
LLPS-Zyt-0449Zymoseptoria tritici47.688e-40 143
LLPS-Map-1034Magnaporthe poae47.652e-37 138
LLPS-Scs-1004Sclerotinia sclerotiorum47.582e-27 109
LLPS-Lem-0098Leptosphaeria maculans47.442e-40 145
LLPS-Ved-1094Verticillium dahliae47.267e-38 138
LLPS-Pytr-0537Pyrenophora triticirepentis47.133e-40 144
LLPS-Asg-0377Ashbya gossypii47.021e-34 130
LLPS-Beb-0747Beauveria bassiana46.942e-40 145
LLPS-Phn-0372Phaeosphaeria nodorum46.637e-40 144
LLPS-Pyt-0917Pyrenophora teres46.52e-39 142
LLPS-Kop-1117Komagataella pastoris46.452e-35 132
LLPS-Dos-0455Dothistroma septosporum46.368e-37 135
LLPS-Tum-1505Tuber melanosporum46.262e-38 139
LLPS-Coo-0397Colletotrichum orbiculare46.113e-42 150
LLPS-Mao-1130Magnaporthe oryzae46.05e-40 145
LLPS-Cogr-0119Colletotrichum graminicola45.572e-39 142
LLPS-Mel-1260Melampsora laricipopulina45.312e-31 116
LLPS-Cog-0734Colletotrichum gloeosporioides44.582e-39 142
LLPS-Chc-0755Chondrus crispus37.843e-26 108
LLPS-Dac-0240Daucus carota34.07e-1780.1
LLPS-Osl-1135Ostreococcus lucimarinus29.374e-1161.6