• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ved-1443
VDAG_04134

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Eukaryotic translation initiation factor 3 subunit M
Gene Name: VDAG_04134
Ensembl Gene: VDAG_04134
Ensembl Protein: EGY22696
Organism: Verticillium dahliae
Taxa ID: 498257
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEGY22696EGY22696
UniProtG2X2U0, G2X2U0_VERDV
GeneBankDS572701EGY22696.1
RefSeqXM_009650581.1XP_009648876.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAGLTTQNA  QPQLLFVDGT  FPELAGEMAD  YLHIADEVKP  LLEDESKKDE  ALAKLVRSSS  60
61    ALTSVPEKEF  TAASNLMIHL  VMQSNEPKKH  LPALCQAFSK  PIATSPINGV  GLSLNALTTV  120
121   FNLIDPKNPI  RFNVFSAILK  FLKAHGMFDT  IEPYLKHIPT  WFDDWNTGEE  YQRNMYVDIS  180
181   EVAAEAGQDE  QSYEYLLKAL  RTFDADDKEE  LASEEAQELS  LRAVKEALLS  PTHLLFTDVR  240
241   SIPSVQNLSE  THPVWSQLLD  IFAEQDLEDY  NDFNDEHEGF  VEKEELDGDR  LLRKMRLLTF  300
301   ASLAAQTTSR  RIEYASIAKA  LQVPSEDVEL  WAIDIIRAGL  VEGRLSQQEK  VFLVHKVTYR  360
361   VFGTRQWQEL  ATRLDSWRNT  LTGLNEVLRK  EEANAKAQKE  REVQELERKL  QGAGLEGGSG  420
421   GGAGGRQRGG  NQGRRDNRER  EPREPKEPRE  PKLRTDDDD  459
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGCTG  GATTGACTAC  CCAGAATGCG  CAGCCGCAGC  TGCTGTTCGT  GGACGGCACC  60
61    TTCCCCGAGC  TGGCTGGCGA  GATGGCAGAC  TACCTCCACA  TCGCCGACGA  GGTCAAGCCC  120
121   CTGCTGGAGG  ACGAGTCGAA  GAAGGATGAG  GCCCTCGCCA  AGCTTGTGCG  CTCCTCCTCG  180
181   GCTCTGACCT  CTGTCCCCGA  GAAGGAGTTC  ACCGCCGCGT  CCAACCTCAT  GATCCACCTC  240
241   GTCATGCAGT  CCAACGAGCC  CAAGAAGCAC  CTGCCCGCGC  TGTGCCAGGC  CTTCAGCAAG  300
301   CCCATCGCCA  CGTCGCCCAT  CAACGGCGTC  GGCCTGAGCC  TCAACGCCCT  GACGACCGTG  360
361   TTCAACCTCA  TCGACCCCAA  GAACCCGATT  CGCTTCAACG  TCTTCTCAGC  CATTCTCAAG  420
421   TTCCTCAAGG  CACACGGCAT  GTTCGACACG  ATCGAGCCCT  ACCTCAAGCA  CATTCCCACC  480
481   TGGTTTGATG  ACTGGAACAC  GGGCGAGGAG  TACCAGCGGA  ATATGTATGT  CGACATTTCT  540
541   GAGGTTGCGG  CCGAGGCAGG  CCAGGACGAA  CAGAGCTACG  AGTACCTTCT  CAAGGCCCTG  600
601   CGCACGTTCG  ACGCCGACGA  CAAGGAGGAG  CTCGCCTCCG  AGGAGGCTCA  GGAGCTGTCG  660
661   CTGCGCGCCG  TCAAGGAGGC  CCTCCTGTCG  CCCACGCACC  TCCTCTTCAC  CGATGTCCGC  720
721   AGCATACCCA  GTGTCCAGAA  CCTCAGCGAG  ACGCACCCCG  TGTGGTCGCA  GCTGCTGGAC  780
781   ATTTTCGCCG  AGCAGGACCT  CGAGGACTAC  AACGACTTCA  ACGACGAGCA  CGAGGGCTTC  840
841   GTCGAGAAGG  AGGAGCTCGA  CGGCGACCGC  CTGCTCCGCA  AGATGCGTCT  CCTCACATTC  900
901   GCCAGCCTCG  CGGCGCAGAC  GACGAGCCGC  CGCATCGAGT  ACGCGTCCAT  CGCCAAGGCG  960
961   CTGCAGGTGC  CGTCCGAGGA  CGTGGAGCTG  TGGGCCATTG  ACATTATCCG  CGCCGGCCTC  1020
1021  GTCGAGGGCC  GCCTCTCGCA  GCAGGAGAAG  GTCTTCCTCG  TGCACAAGGT  CACGTACCGC  1080
1081  GTCTTCGGCA  CGAGGCAGTG  GCAGGAGCTC  GCCACGCGTC  TCGACTCGTG  GCGCAACACG  1140
1141  CTCACGGGGC  TCAACGAGGT  GCTTCGCAAG  GAGGAGGCCA  ACGCCAAGGC  TCAGAAGGAG  1200
1201  CGCGAGGTGC  AGGAGCTCGA  GCGCAAGCTC  CAGGGCGCCG  GCCTCGAGGG  CGGCAGTGGC  1260
1261  GGTGGCGCCG  GTGGACGGCA  GCGCGGCGGC  AACCAGGGCC  GCCGGGACAA  CAGGGAGCGT  1320
1321  GAGCCCAGGG  AGCCCAAGGA  GCCCCGGGAA  CCGAAGCTGA  GGACGGACGA  CGACGACTGA  1380

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Eukaryotic 43S preinitiation complex
Cellular Component
Eukaryotic 48S preinitiation complex
Cellular Component
Eukaryotic translation initiation factor 3 complex, eIF3m
Molecular Function
Translation initiation factor activity
Biological Process
Formation of cytoplasmic translation initiation complex

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cogr-1488Colletotrichum graminicola79.320.0 670
LLPS-Coo-0138Colletotrichum orbiculare76.10.0 646
LLPS-Cog-1282Colletotrichum gloeosporioides73.90.0 603
LLPS-Beb-0777Beauveria bassiana66.830.0 540
LLPS-Fus-1361Fusarium solani65.290.0 537
LLPS-Trr-0949Trichoderma reesei64.060.0 524
LLPS-Fuv-1115Fusarium verticillioides63.431e-179 517
LLPS-Fuo-1337Fusarium oxysporum63.391e-180 520
LLPS-Trv-0450Trichoderma virens62.999e-178 512
LLPS-Nec-1053Neurospora crassa58.353e-164 478
LLPS-Mao-0818Magnaporthe oryzae55.722e-155 455
LLPS-Gag-1580Gaeumannomyces graminis53.522e-142 422
LLPS-Blg-1327Blumeria graminis53.032e-143 423
LLPS-Pytr-0039Pyrenophora triticirepentis49.264e-123 373
LLPS-Pyt-1099Pyrenophora teres49.022e-122 371
LLPS-Lem-0844Leptosphaeria maculans47.793e-122 372
LLPS-Phn-0993Phaeosphaeria nodorum46.63e-116 355
LLPS-Dos-1048Dothistroma septosporum43.996e-107 331
LLPS-Zyt-0150Zymoseptoria tritici42.751e-90 296
LLPS-Tum-1204Tuber melanosporum39.87e-98 307
LLPS-Aso-1010Aspergillus oryzae38.173e-75 250
LLPS-Asf-0470Aspergillus flavus38.173e-75 250
LLPS-Ast-0394Aspergillus terreus37.963e-71 239
LLPS-Asn-1371Aspergillus nidulans37.562e-64 221
LLPS-Nef-1241Neosartorya fischeri37.473e-79 260
LLPS-Asfu-1660Aspergillus fumigatus37.478e-79 259
LLPS-Asc-0252Aspergillus clavatus36.341e-72 243
LLPS-Asni-0615Aspergillus niger35.262e-50 181
LLPS-Yal-1511Yarrowia lipolytica33.522e-2096.7
LLPS-Usm-1411Ustilago maydis33.331e-0654.3
LLPS-Scj-1511Schizosaccharomyces japonicus32.745e-48 176
LLPS-Spr-0507Sporisorium reilianum32.092e-41 157
LLPS-Dac-1404Daucus carota31.217e-1787.0
LLPS-Arl-2256Arabidopsis lyrata31.186e-36 142
LLPS-Scc-1534Schizosaccharomyces cryophilus30.697e-55 194
LLPS-Sot-1181Solanum tuberosum30.652e-34 138
LLPS-Art-2879Arabidopsis thaliana30.597e-37 145
LLPS-Crn-1067Cryptococcus neoformans30.485e-1787.0
LLPS-Brr-1089Brassica rapa30.272e-33 135
LLPS-Brn-3417Brassica napus30.063e-33 134
LLPS-Sol-1729Solanum lycopersicum30.033e-33 134
LLPS-Scp-1355Schizosaccharomyces pombe29.978e-48 175
LLPS-Cus-2097Cucumis sativus29.941e-34 138
LLPS-Bro-1154Brassica oleracea29.769e-33 132
LLPS-Abg-0804Absidia glauca29.537e-46 169
LLPS-Prp-2193Prunus persica29.224e-32 131
LLPS-Cii-1217Ciona intestinalis29.143e-31 128
LLPS-Gas-1119Galdieria sulphuraria29.139e-24 105
LLPS-Nia-1369Nicotiana attenuata28.914e-32 130
LLPS-Viv-1470Vitis vinifera28.452e-30 126
LLPS-Mae-1202Manihot esculenta27.956e-30 124
LLPS-Brd-1873Brachypodium distachyon27.475e-23 104
LLPS-Cae-1815Caenorhabditis elegans27.387e-0961.6
LLPS-Chc-1047Chondrus crispus27.191e-2097.4
LLPS-Mua-0323Musa acuminata27.112e-29 123
LLPS-Php-0681Physcomitrella patens26.965e-32 130
LLPS-Hea-0533Helianthus annuus26.932e-27 116
LLPS-Thc-1361Theobroma cacao26.825e-31 127
LLPS-Amt-2284Amborella trichopoda26.764e-29 122
LLPS-Orr-1054Oryza rufipogon26.717e-25 110
LLPS-Orm-1049Oryza meridionalis26.711e-24 109
LLPS-Orb-0146Oryza barthii26.711e-24 109
LLPS-Orgl-2130Oryza glumaepatula26.711e-24 109
LLPS-Via-0348Vigna angularis26.635e-25 110
LLPS-Gor-2052Gossypium raimondii26.54e-28 119
LLPS-Hov-2041Hordeum vulgare26.432e-23 104
LLPS-Vir-1801Vigna radiata26.411e-22 103
LLPS-Met-1623Medicago truncatula26.337e-25 109
LLPS-Cis-0028Ciona savignyi26.229e-28 117
LLPS-Lep-1263Leersia perrieri26.222e-23 105
LLPS-Glm-1824Glycine max26.042e-28 120
LLPS-Orni-1638Oryza nivara25.992e-23 105
LLPS-Pot-1176Populus trichocarpa25.971e-26 114
LLPS-Phv-1099Phaseolus vulgaris25.964e-25 110
LLPS-Coc-0769Corchorus capsularis25.942e-29 122
LLPS-Tra-2868Triticum aestivum25.771e-23 105
LLPS-Sem-1209Selaginella moellendorffii25.683e-29 122
LLPS-Sob-0987Sorghum bicolor25.531e-23 106
LLPS-Osl-0476Ostreococcus lucimarinus25.517e-1271.2
LLPS-Fia-3566Ficedula albicollis25.466e-28 117
LLPS-Drm-2260Drosophila melanogaster25.326e-22 100
LLPS-Tag-2495Taeniopygia guttata25.186e-28 117
LLPS-Ors-0184Oryza sativa25.147e-26 112
LLPS-Ori-1085Oryza indica25.141e-25 111
LLPS-Xim-2562Xiphophorus maculatus24.939e-29 120
LLPS-Org-1057Oryza glaberrima24.865e-25 110
LLPS-Orp-2198Oryza punctata24.621e-24 109
LLPS-Pof-4042Poecilia formosa24.561e-26 114
LLPS-Orl-0550Oryzias latipes24.412e-29 122
LLPS-Zem-1511Zea mays24.341e-22 103
LLPS-Sei-2222Setaria italica23.999e-26 112
LLPS-Anc-2618Anolis carolinensis23.888e-29 120
LLPS-Xet-2861Xenopus tropicalis23.886e-26 112
LLPS-Scf-3308Scleropages formosus23.791e-23 105
LLPS-Myl-2203Myotis lucifugus23.751e-27 117
LLPS-Mod-3495Monodelphis domestica23.625e-29 121
LLPS-Sah-3875Sarcophilus harrisii23.625e-29 121
LLPS-Dar-0408Danio rerio23.569e-28 117
LLPS-Ora-2429Ornithorhynchus anatinus23.532e-29 122
LLPS-Rhb-3728Rhinopithecus bieti23.423e-28 119
LLPS-Pes-2263Pelodiscus sinensis23.361e-28 120
LLPS-Anp-0356Anas platyrhynchos23.242e-28 119
LLPS-Man-2330Macaca nemestrina23.243e-28 119
LLPS-Fec-1751Felis catus23.243e-28 119
LLPS-Hos-1475Homo sapiens23.243e-28 119
LLPS-Pap-3084Pan paniscus23.243e-28 119
LLPS-Urm-1068Ursus maritimus23.243e-28 119
LLPS-Pat-2427Pan troglodytes23.243e-28 119
LLPS-Orn-3443Oreochromis niloticus23.241e-27 117
LLPS-Orc-4247Oryctolagus cuniculus23.243e-28 119
LLPS-Mam-3436Macaca mulatta23.243e-28 119
LLPS-Caf-3801Canis familiaris23.243e-28 119
LLPS-Poa-0139Pongo abelii23.243e-28 119
LLPS-Nol-4108Nomascus leucogenys23.243e-28 119
LLPS-Ict-2988Ictidomys tridecemlineatus23.243e-28 119
LLPS-Cas-0386Carlito syrichta23.244e-28 119
LLPS-Leo-1557Lepisosteus oculatus23.245e-27 115
LLPS-Sus-4198Sus scrofa23.242e-28 119
LLPS-Aon-1791Aotus nancymaae23.242e-28 119
LLPS-Cea-1460Cercocebus atys23.243e-28 119
LLPS-Chs-3306Chlorocebus sabaeus23.243e-28 119
LLPS-Maf-2845Macaca fascicularis23.243e-28 119
LLPS-Caj-1040Callithrix jacchus23.244e-28 119
LLPS-Gog-4239Gorilla gorilla23.243e-28 119
LLPS-Bot-0728Bos taurus23.243e-28 119
LLPS-Tut-2193Tursiops truncatus23.241e-28 120
LLPS-Ova-0408Ovis aries23.243e-28 119
LLPS-Aim-2309Ailuropoda melanoleuca23.243e-28 119
LLPS-Mup-3877Mustela putorius furo23.243e-28 119
LLPS-Mal-0421Mandrillus leucophaeus23.243e-28 119
LLPS-Paa-4099Papio anubis23.243e-28 119
LLPS-Asm-3199Astyanax mexicanus23.178e-27 114
LLPS-Meg-2367Meleagris gallopavo23.122e-27 116
LLPS-Lac-1664Latimeria chalumnae23.18e-27 114
LLPS-Gaga-2766Gallus gallus23.11e-27 117
LLPS-Loa-4250Loxodonta africana22.942e-27 116
LLPS-Scm-0227Scophthalmus maximus22.942e-26 114
LLPS-Mum-3116Mus musculus22.942e-27 116
LLPS-Mea-2694Mesocricetus auratus22.942e-27 116
LLPS-Icp-3495Ictalurus punctatus22.943e-27 116
LLPS-Ran-3154Rattus norvegicus22.942e-27 116
LLPS-Cap-4493Cavia porcellus22.652e-27 116
LLPS-Fud-0741Fukomys damarensis22.654e-27 115
LLPS-Kop-0709Komagataella pastoris22.546e-1271.2
LLPS-Ten-3249Tetraodon nigroviridis22.291e-25 111
LLPS-Eqc-3796Equus caballus22.283e-22 102
LLPS-Gaa-0417Gasterosteus aculeatus22.028e-24 106
LLPS-Otg-0102Otolemur garnettii21.174e-1270.9
LLPS-Tar-2099Takifugu rubripes20.639e-1373.6