LLPS-Dac-1404
DCAR_011034
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Eukaryotic translation initiation factor 3 subunit M |
| Gene Name: | DCAR_011034 |
| Ensembl Gene: | DCAR_011034 |
| Ensembl Protein: | KZN02280 |
| Organism: | Daucus carota |
| Taxa ID: | 79200 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | KZN02280 | KZN02280 |
| UniProt | A0A166B2S0, A0A166B2S0_DAUCS | |
| GeneBank | LNRQ01000003 | KZN02280.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MTTLVPTSEE DPALSVVRFT SEISWADAGP EVAEPQVSRL CLEASECMLA GRWLDLTSLM 60 61 LTSADVIFSK ASDKDLECIF TVICNLVKKT GSLDEALEMA KLISTKVTQQ PNDKPALRLK 120 121 IMFNLYNLLE NPYSRFFVYM KALNLAVNGK VIEHVVPSFK KIDSFLKEWN LGVQDQRELF 180 181 LSVSNILKES KSSAKDSFKF LTKYLATFSD EDAQNMAEAK EEAVRAVVEF VKTPDMFQLH 240 241 GSRVALWIRI PDRTFPNAGR HRPSSLRFAF QFGKSGEPLQ LPRTMLKSKE KRKYGREDRL 300 301 TADCASLYEE EKERSKSEVK KEEDEVKKTP FALSVCDLLD MPAVAQLEKD AKYESVYQLL 360 361 KIFLTQKLDA YLEFHSANSS LLKNYGILHE DCVAKMRLMS LVDLGANESG HIPYDLIKHT 420 421 LQIADDEVEG WVVKAITAKL LDCKIDQMNQ IIIVSRCTER VFGLNQWQSL RTKLATWRGN 480 481 ISNVIATIQA NKVAEDGAQL MQGLAIH 507 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGACGACTC TCGTACCAAC CTCCGAAGAA GATCCAGCCC TCTCCGTCGT TCGCTTCACC 60 61 TCCGAGATCT CATGGGCCGA TGCCGGTCCC GAGGTTGCTG AGCCACAAGT GAGTCGTTTG 120 121 TGCTTGGAGG CTTCGGAATG TATGCTCGCT GGAAGATGGT TGGATTTGAC CTCTCTTATG 180 181 CTCACTTCCG CTGATGTCAT TTTCTCCAAA GCTTCCGACA AAGATCTTGA GTGCATCTTT 240 241 ACTGTCATAT GCAATCTTGT CAAGAAGACA GGCAGTCTTG ATGAAGCACT GGAGATGGCA 300 301 AAGCTCATCT CCACCAAGGT CACTCAACAG CCTAATGATA AGCCCGCTCT TCGTCTCAAA 360 361 ATCATGTTTA ATCTGTACAA CCTATTGGAG AATCCATACA GTCGGTTCTT TGTATACATG 420 421 AAGGCCCTTA ATTTGGCTGT CAACGGGAAG GTCATTGAAC ATGTTGTTCC CTCTTTCAAG 480 481 AAAATTGATA GTTTTCTCAA GGAGTGGAAT CTTGGGGTTC AGGATCAGAG AGAACTCTTT 540 541 CTCTCTGTGT CGAATATTTT GAAAGAAAGT AAAAGCTCGG CTAAGGATTC TTTCAAATTT 600 601 CTGACCAAAT ATCTAGCAAC ATTTTCTGAT GAAGATGCAC AGAATATGGC AGAAGCTAAA 660 661 GAAGAAGCAG TACGAGCCGT TGTTGAATTT GTGAAAACAC CAGACATGTT TCAGTTGCAC 720 721 GGTTCGCGGG TCGCCCTATG GATCCGCATA CCAGATCGGA CGTTCCCGAA CGCGGGTCGA 780 781 CATCGACCCA GTTCCTTGCG GTTCGCGTTC CAGTTCGGTA AATCCGGCGA ACCACTGCAA 840 841 CTCCCACGAA CAATGTTAAA ATCGAAAGAA AAGAGAAAAT ATGGACGAGA AGACAGGCTG 900 901 ACAGCAGATT GTGCATCTTT ATACGAAGAA GAGAAGGAGA GAAGCAAAAG TGAAGTGAAG 960 961 AAAGAAGAAG ATGAAGTGAA GAAGACGCCT TTTGCTCTGT CTGTATGTGA CTTGCTTGAT 1020 1021 ATGCCTGCGG TAGCGCAATT GGAGAAAGAT GCAAAATATG AGTCGGTATA TCAACTTCTG 1080 1081 AAGATTTTCC TGACTCAAAA GCTAGATGCT TACTTGGAAT TTCATTCAGC AAATTCTTCA 1140 1141 TTGCTGAAAA ACTATGGTAT TCTTCATGAG GACTGTGTAG CAAAGATGAG ATTGATGTCG 1200 1201 TTGGTTGATC TTGGGGCCAA TGAGTCTGGT CATATTCCAT ATGATCTAAT TAAACATACA 1260 1261 TTACAAATTG CCGATGACGA GGTGGAAGGA TGGGTTGTTA AGGCAATCAC CGCCAAGTTG 1320 1321 TTGGACTGCA AGATTGATCA GATGAATCAA ATAATTATCG TGAGCCGGTG CACTGAGCGA 1380 1381 GTATTTGGGT TGAATCAATG GCAGTCTCTC CGGACGAAGC TGGCAACATG GAGGGGTAAT 1440 1441 ATTTCAAACG TAATCGCCAC AATCCAAGCA AACAAGGTGG CGGAAGATGG TGCACAGTTG 1500 1501 ATGCAGGGCT TGGCAATACA TTGA 1524 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Eukaryotic 43S preinitiation complex | |
Cellular Component | Eukaryotic 48S preinitiation complex | |
Cellular Component | Eukaryotic translation initiation factor 3 complex, eIF3m | |
Molecular Function | Translation initiation factor activity | |
Biological Process | Formation of cytoplasmic translation initiation complex |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Viv-1470 | Vitis vinifera | 81.09 | 2e-127 | 384 |
| LLPS-Prp-2193 | Prunus persica | 79.83 | 2e-124 | 377 |
| LLPS-Coc-0769 | Corchorus capsularis | 79.41 | 2e-123 | 374 |
| LLPS-Nia-1369 | Nicotiana attenuata | 79.41 | 1e-125 | 380 |
| LLPS-Mae-1202 | Manihot esculenta | 79.17 | 3e-120 | 366 |
| LLPS-Thc-1361 | Theobroma cacao | 78.57 | 6e-123 | 373 |
| LLPS-Pot-1176 | Populus trichocarpa | 77.92 | 3e-120 | 366 |
| LLPS-Hea-0533 | Helianthus annuus | 77.31 | 5e-119 | 363 |
| LLPS-Gor-2052 | Gossypium raimondii | 77.22 | 5e-118 | 361 |
| LLPS-Cus-2097 | Cucumis sativus | 76.74 | 4e-91 | 291 |
| LLPS-Sot-1181 | Solanum tuberosum | 76.47 | 5e-121 | 368 |
| LLPS-Sol-1729 | Solanum lycopersicum | 75.0 | 1e-88 | 285 |
| LLPS-Vir-1801 | Vigna radiata | 73.37 | 1e-85 | 276 |
| LLPS-Via-0348 | Vigna angularis | 72.19 | 4e-84 | 273 |
| LLPS-Met-1623 | Medicago truncatula | 72.09 | 2e-83 | 271 |
| LLPS-Mua-0323 | Musa acuminata | 72.08 | 1e-107 | 334 |
| LLPS-Glm-1824 | Glycine max | 70.35 | 1e-84 | 274 |
| LLPS-Org-1057 | Oryza glaberrima | 68.6 | 8e-78 | 256 |
| LLPS-Zem-1511 | Zea mays | 68.6 | 4e-78 | 257 |
| LLPS-Orr-1054 | Oryza rufipogon | 68.6 | 1e-77 | 257 |
| LLPS-Orm-1049 | Oryza meridionalis | 68.6 | 2e-77 | 256 |
| LLPS-Ors-0184 | Oryza sativa | 68.6 | 5e-78 | 257 |
| LLPS-Tra-2868 | Triticum aestivum | 68.6 | 2e-78 | 258 |
| LLPS-Brd-1873 | Brachypodium distachyon | 68.6 | 1e-72 | 243 |
| LLPS-Orgl-2130 | Oryza glumaepatula | 68.6 | 2e-77 | 256 |
| LLPS-Orni-1638 | Oryza nivara | 68.6 | 2e-77 | 256 |
| LLPS-Orb-0146 | Oryza barthii | 68.6 | 2e-77 | 256 |
| LLPS-Ori-1085 | Oryza indica | 68.6 | 1e-77 | 256 |
| LLPS-Phv-1099 | Phaseolus vulgaris | 68.07 | 2e-105 | 328 |
| LLPS-Amt-2284 | Amborella trichopoda | 67.92 | 2e-73 | 244 |
| LLPS-Sob-0987 | Sorghum bicolor | 67.44 | 3e-76 | 252 |
| LLPS-Orp-2198 | Oryza punctata | 67.44 | 3e-76 | 253 |
| LLPS-Hov-2041 | Hordeum vulgare | 66.86 | 1e-77 | 254 |
| LLPS-Bro-1154 | Brassica oleracea | 66.48 | 2e-78 | 258 |
| LLPS-Brr-1089 | Brassica rapa | 66.48 | 5e-78 | 257 |
| LLPS-Lep-1263 | Leersia perrieri | 66.28 | 4e-75 | 249 |
| LLPS-Art-2879 | Arabidopsis thaliana | 65.55 | 7e-99 | 311 |
| LLPS-Arl-2256 | Arabidopsis lyrata | 64.8 | 4e-76 | 252 |
| LLPS-Brn-3417 | Brassica napus | 64.79 | 1e-96 | 305 |
| LLPS-Sei-2222 | Setaria italica | 64.53 | 4e-74 | 247 |
| LLPS-Sem-1209 | Selaginella moellendorffii | 59.66 | 1e-84 | 274 |
| LLPS-Php-0681 | Physcomitrella patens | 59.51 | 2e-59 | 208 |
| LLPS-Dio-4162 | Dipodomys ordii | 42.0 | 3e-06 | 51.2 |
| LLPS-Osl-0476 | Ostreococcus lucimarinus | 41.79 | 1e-23 | 106 |
| LLPS-Gas-1119 | Galdieria sulphuraria | 40.48 | 8e-24 | 106 |
| LLPS-Tag-2495 | Taeniopygia guttata | 40.46 | 2e-25 | 111 |
| LLPS-Gaga-2766 | Gallus gallus | 39.69 | 5e-25 | 110 |
| LLPS-Anc-2618 | Anolis carolinensis | 39.69 | 2e-24 | 108 |
| LLPS-Pes-2263 | Pelodiscus sinensis | 39.69 | 1e-25 | 111 |
| LLPS-Fia-3566 | Ficedula albicollis | 39.69 | 2e-25 | 110 |
| LLPS-Meg-2367 | Meleagris gallopavo | 39.69 | 4e-25 | 110 |
| LLPS-Lac-1664 | Latimeria chalumnae | 39.69 | 1e-24 | 109 |
| LLPS-Anp-0356 | Anas platyrhynchos | 39.69 | 4e-25 | 110 |
| LLPS-Leo-1557 | Lepisosteus oculatus | 39.69 | 8e-25 | 109 |
| LLPS-Scm-0227 | Scophthalmus maximus | 39.42 | 1e-26 | 114 |
| LLPS-Cas-0386 | Carlito syrichta | 38.93 | 1e-24 | 108 |
| LLPS-Nol-4108 | Nomascus leucogenys | 38.93 | 2e-24 | 108 |
| LLPS-Ict-2988 | Ictidomys tridecemlineatus | 38.93 | 2e-24 | 108 |
| LLPS-Poa-0139 | Pongo abelii | 38.93 | 2e-24 | 108 |
| LLPS-Caf-3801 | Canis familiaris | 38.93 | 2e-24 | 108 |
| LLPS-Cap-4493 | Cavia porcellus | 38.93 | 1e-24 | 108 |
| LLPS-Eqc-3796 | Equus caballus | 38.93 | 2e-24 | 109 |
| LLPS-Mam-3436 | Macaca mulatta | 38.93 | 2e-24 | 108 |
| LLPS-Orc-4247 | Oryctolagus cuniculus | 38.93 | 2e-24 | 108 |
| LLPS-Rhb-3728 | Rhinopithecus bieti | 38.93 | 1e-24 | 108 |
| LLPS-Hos-1475 | Homo sapiens | 38.93 | 2e-24 | 108 |
| LLPS-Pat-2427 | Pan troglodytes | 38.93 | 2e-24 | 108 |
| LLPS-Pap-3084 | Pan paniscus | 38.93 | 2e-24 | 108 |
| LLPS-Urm-1068 | Ursus maritimus | 38.93 | 2e-24 | 108 |
| LLPS-Mod-3495 | Monodelphis domestica | 38.93 | 1e-24 | 108 |
| LLPS-Fec-1751 | Felis catus | 38.93 | 2e-24 | 108 |
| LLPS-Man-2330 | Macaca nemestrina | 38.93 | 2e-24 | 108 |
| LLPS-Loa-4250 | Loxodonta africana | 38.93 | 1e-24 | 108 |
| LLPS-Ran-3154 | Rattus norvegicus | 38.93 | 1e-24 | 108 |
| LLPS-Paa-4099 | Papio anubis | 38.93 | 2e-24 | 108 |
| LLPS-Mal-0421 | Mandrillus leucophaeus | 38.93 | 2e-24 | 108 |
| LLPS-Aim-2309 | Ailuropoda melanoleuca | 38.93 | 2e-24 | 108 |
| LLPS-Mup-3877 | Mustela putorius furo | 38.93 | 2e-24 | 108 |
| LLPS-Myl-2203 | Myotis lucifugus | 38.93 | 2e-24 | 108 |
| LLPS-Ova-0408 | Ovis aries | 38.93 | 2e-24 | 108 |
| LLPS-Tut-2193 | Tursiops truncatus | 38.93 | 2e-24 | 108 |
| LLPS-Bot-0728 | Bos taurus | 38.93 | 2e-24 | 108 |
| LLPS-Gog-4239 | Gorilla gorilla | 38.93 | 2e-24 | 108 |
| LLPS-Fud-0741 | Fukomys damarensis | 38.93 | 2e-24 | 108 |
| LLPS-Caj-1040 | Callithrix jacchus | 38.93 | 4e-24 | 108 |
| LLPS-Maf-2845 | Macaca fascicularis | 38.93 | 2e-24 | 108 |
| LLPS-Mum-3116 | Mus musculus | 38.93 | 1e-24 | 108 |
| LLPS-Mea-2694 | Mesocricetus auratus | 38.93 | 1e-24 | 108 |
| LLPS-Chs-3306 | Chlorocebus sabaeus | 38.93 | 2e-24 | 108 |
| LLPS-Sus-4198 | Sus scrofa | 38.93 | 2e-24 | 108 |
| LLPS-Aon-1791 | Aotus nancymaae | 38.93 | 2e-24 | 108 |
| LLPS-Sah-3875 | Sarcophilus harrisii | 38.93 | 1e-24 | 108 |
| LLPS-Cea-1460 | Cercocebus atys | 38.93 | 2e-24 | 108 |
| LLPS-Ten-3249 | Tetraodon nigroviridis | 38.69 | 7e-26 | 112 |
| LLPS-Orn-3443 | Oreochromis niloticus | 38.69 | 6e-26 | 112 |
| LLPS-Pof-4042 | Poecilia formosa | 38.69 | 1e-24 | 108 |
| LLPS-Gaa-0417 | Gasterosteus aculeatus | 38.69 | 3e-26 | 114 |
| LLPS-Xim-2562 | Xiphophorus maculatus | 38.24 | 1e-25 | 112 |
| LLPS-Scf-3308 | Scleropages formosus | 37.96 | 4e-24 | 107 |
| LLPS-Icp-3495 | Ictalurus punctatus | 37.96 | 1e-25 | 112 |
| LLPS-Orl-0550 | Oryzias latipes | 37.96 | 2e-26 | 114 |
| LLPS-Tar-2099 | Takifugu rubripes | 37.5 | 8e-09 | 61.6 |
| LLPS-Cogr-1488 | Colletotrichum graminicola | 36.97 | 1e-22 | 104 |
| LLPS-Xet-2861 | Xenopus tropicalis | 36.77 | 5e-24 | 107 |
| LLPS-Abg-0804 | Absidia glauca | 36.73 | 1e-22 | 103 |
| LLPS-Ora-2429 | Ornithorhynchus anatinus | 36.64 | 7e-22 | 101 |
| LLPS-Usm-0706 | Ustilago maydis | 36.63 | 2e-10 | 67.0 |
| LLPS-Cis-0028 | Ciona savignyi | 36.6 | 1e-20 | 97.4 |
| LLPS-Asm-3199 | Astyanax mexicanus | 36.5 | 1e-23 | 106 |
| LLPS-Fus-1361 | Fusarium solani | 35.37 | 4e-19 | 94.0 |
| LLPS-Drm-2260 | Drosophila melanogaster | 35.37 | 1e-20 | 97.8 |
| LLPS-Dar-0408 | Danio rerio | 35.29 | 2e-22 | 102 |
| LLPS-Fuo-1337 | Fusarium oxysporum | 34.76 | 4e-18 | 90.9 |
| LLPS-Cii-1217 | Ciona intestinalis | 34.62 | 4e-21 | 99.0 |
| LLPS-Dos-1048 | Dothistroma septosporum | 34.59 | 1e-20 | 98.2 |
| LLPS-Phn-0993 | Phaeosphaeria nodorum | 34.55 | 1e-23 | 107 |
| LLPS-Asni-0615 | Aspergillus niger | 34.51 | 1e-18 | 91.3 |
| LLPS-Zyt-0150 | Zymoseptoria tritici | 34.48 | 4e-17 | 88.6 |
| LLPS-Beb-0777 | Beauveria bassiana | 34.38 | 3e-17 | 88.2 |
| LLPS-Blg-1327 | Blumeria graminis | 34.23 | 1e-17 | 89.0 |
| LLPS-Fuv-1115 | Fusarium verticillioides | 34.15 | 8e-17 | 87.0 |
| LLPS-Ast-0394 | Aspergillus terreus | 33.8 | 3e-18 | 91.3 |
| LLPS-Asf-0470 | Aspergillus flavus | 33.8 | 6e-18 | 90.5 |
| LLPS-Aso-1010 | Aspergillus oryzae | 33.8 | 6e-18 | 90.5 |
| LLPS-Asc-0252 | Aspergillus clavatus | 33.8 | 1e-18 | 92.4 |
| LLPS-Asfu-1660 | Aspergillus fumigatus | 33.1 | 2e-17 | 89.4 |
| LLPS-Nef-1241 | Neosartorya fischeri | 33.1 | 1e-17 | 89.7 |
| LLPS-Pytr-0039 | Pyrenophora triticirepentis | 32.7 | 2e-20 | 97.8 |
| LLPS-Pyt-1099 | Pyrenophora teres | 32.7 | 3e-20 | 97.4 |
| LLPS-Chc-1047 | Chondrus crispus | 32.69 | 4e-22 | 102 |
| LLPS-Lem-0844 | Leptosphaeria maculans | 32.53 | 5e-20 | 97.1 |
| LLPS-Coo-0138 | Colletotrichum orbiculare | 32.05 | 4e-19 | 94.0 |
| LLPS-Trr-0949 | Trichoderma reesei | 31.95 | 1e-17 | 89.4 |
| LLPS-Nec-1053 | Neurospora crassa | 31.9 | 2e-19 | 94.7 |
| LLPS-Asn-1371 | Aspergillus nidulans | 31.76 | 6e-13 | 75.1 |
| LLPS-Cog-1282 | Colletotrichum gloeosporioides | 31.71 | 4e-13 | 75.1 |
| LLPS-Spr-0507 | Sporisorium reilianum | 31.67 | 4e-15 | 81.3 |
| LLPS-Trv-0450 | Trichoderma virens | 31.55 | 3e-18 | 91.3 |
| LLPS-Ved-1443 | Verticillium dahliae | 30.99 | 6e-17 | 87.4 |
| LLPS-Cae-1035 | Caenorhabditis elegans | 30.47 | 5e-07 | 56.2 |
| LLPS-Scc-1534 | Schizosaccharomyces cryophilus | 30.14 | 5e-15 | 80.9 |
| LLPS-Mao-0818 | Magnaporthe oryzae | 29.89 | 4e-17 | 87.8 |
| LLPS-Yal-1511 | Yarrowia lipolytica | 29.73 | 2e-06 | 54.3 |
| LLPS-Tru-0854 | Triticum urartu | 29.19 | 3e-08 | 60.1 |
| LLPS-Tum-1204 | Tuber melanosporum | 28.66 | 5e-19 | 93.6 |
| LLPS-Scj-1511 | Schizosaccharomyces japonicus | 28.4 | 5e-12 | 72.0 |
| LLPS-Gag-1580 | Gaeumannomyces graminis | 27.93 | 4e-14 | 78.6 |
| LLPS-Scp-1355 | Schizosaccharomyces pombe | 27.74 | 4e-12 | 72.4 |
| LLPS-Crn-1067 | Cryptococcus neoformans | 26.97 | 9e-10 | 64.7 |
| LLPS-Kop-0709 | Komagataella pastoris | 25.6 | 7e-06 | 52.4 |