LLPS-Ten-0097
CAPZA2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | F-actin-capping protein subunit alpha |
| Gene Name: | CAPZA2 |
| Ensembl Gene: | ENSTNIG00000016059.1 |
| Ensembl Protein: | ENSTNIP00000019149.1 |
| Organism: | Tetraodon nigroviridis |
| Taxa ID: | 99883 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSTNIT00000019377.1 | ENSTNIP00000019149.1 |
| Ensembl | ENSTNIT00000003998.1 | ENSTNIP00000003818.1 |
| UniProt | H3DF55, H3DF55_TETNG |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 RTGSEERKSD SVQVRIAANF VIHAPPGEFN EVFNDVRFLL NNDNLLREGA ANAFAQYNLD 60 61 QFTPVKIEGY EEQVLITEHG DLGNGRVLDP KNKISFKFDH LRKEASDPRP HDVDSSIESW 120 121 RSAVDSAVRV YVKDHYPNGV CTIYGKTIDG HQTIIVCIEC HQFQPKNFWN GRWRSEWKFT 180 181 ISSSSTEVAG IMKIQVHYYE DGNVQLVSHK EVQESMSVSG EASTAKAFVK IMEAAEKDYQ 240 241 TAINENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA 286 |
| Nucleotide CDS Sequence (FASTA) |
1 ATCAGTAAAT GTCGTCAACT CAGCGGAGAG CCGCAGGCTG TCGGCCTGCC TCTTATCACC 60 61 GCTGGGAACC CAACACAACT GTGTCTCCGC AGTGCATTTG CACAGTATAA CTTGGACCAG 120 121 TTTACCCCGG TGAAAATCGA GGGCTATGAA GAACAGGTCT TAATCACAGA GCATGGTGAC 180 181 CTTGGAAACG GCCGGGTCCT GGACCCTAAG AACAAGATCT CCTTCAAGTT TGATCACCTG 240 241 AGGAAGGAGG CCAGTGACCC CCGACCTCAT GACGTTGACA GCTCCATCGA AAGCTGGAGA 300 301 AGCGCTGTGG ACTCTGCCGT CAGAGTCTAC GTCAAGGATC ACTATCCCAA TGGAGTCTGC 360 361 ACCATTTATG GAAAAACCAT CGACGGACAT CAAACCATCA TTGTGTGCAT TGAGTGCCAT 420 421 CAGTTTCAAC CAAAAAACTT CTGGAATGGA CGCTGGAGGT CAGAGTGGAA ATTCACCATT 480 481 TCCTCCTCTT CTACTGAGGT GGCTGGAATC ATGAAGATTC AGGTTCATTA CTATGAAGAC 540 541 GGAAACGTTC AGCTGGTGAG CCACAAAGAG GTCCAGGAGT CCATGTCAGT TTCTACGGCC 600 601 ATCAACGAGA ATTACCAGAC CATGTCGGAC ACTACCTTCA AAGCCTTACG CCGCCAGCTC 660 661 CCTGTGACAC GCACCAAGAT CGACTGGAAC AAGATCCTGA GCTACAAAAT TGGCAAGGAG 720 721 ATGCAGAACG CTTAG 735 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | F-actin capping protein complex | |
Molecular Function | Actin binding | |
Biological Process | Barbed-end actin filament capping |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pof-3335 | Poecilia formosa | 93.26 | 0.0 | 538 |
| LLPS-Orn-2165 | Oreochromis niloticus | 93.07 | 0.0 | 527 |
| LLPS-Tar-1782 | Takifugu rubripes | 92.91 | 0.0 | 556 |
| LLPS-Xim-0796 | Xiphophorus maculatus | 92.91 | 0.0 | 535 |
| LLPS-Orl-0586 | Oryzias latipes | 92.55 | 0.0 | 535 |
| LLPS-Gaa-0666 | Gasterosteus aculeatus | 91.49 | 0.0 | 530 |
| LLPS-Scf-0386 | Scleropages formosus | 89.4 | 0.0 | 521 |
| LLPS-Leo-2179 | Lepisosteus oculatus | 87.59 | 0.0 | 517 |
| LLPS-Meg-2541 | Meleagris gallopavo | 84.25 | 9e-173 | 486 |
| LLPS-Gaga-2783 | Gallus gallus | 82.98 | 2e-175 | 493 |
| LLPS-Bot-1899 | Bos taurus | 82.48 | 3e-169 | 479 |
| LLPS-Tag-3045 | Taeniopygia guttata | 82.27 | 2e-174 | 491 |
| LLPS-Anp-0259 | Anas platyrhynchos | 82.27 | 6e-174 | 489 |
| LLPS-Fia-2312 | Ficedula albicollis | 82.21 | 9e-173 | 486 |
| LLPS-Lac-0386 | Latimeria chalumnae | 82.18 | 9e-167 | 471 |
| LLPS-Mal-2848 | Mandrillus leucophaeus | 82.05 | 2e-168 | 475 |
| LLPS-Fud-2366 | Fukomys damarensis | 82.05 | 4e-168 | 474 |
| LLPS-Mam-1704 | Macaca mulatta | 82.05 | 5e-168 | 475 |
| LLPS-Sah-0136 | Sarcophilus harrisii | 81.91 | 7e-173 | 487 |
| LLPS-Xet-3734 | Xenopus tropicalis | 81.91 | 6e-171 | 482 |
| LLPS-Pap-3969 | Pan paniscus | 81.75 | 2e-168 | 475 |
| LLPS-Urm-3272 | Ursus maritimus | 81.68 | 1e-168 | 475 |
| LLPS-Cas-1795 | Carlito syrichta | 81.67 | 5e-152 | 432 |
| LLPS-Aon-2469 | Aotus nancymaae | 81.62 | 2e-166 | 470 |
| LLPS-Mod-2334 | Monodelphis domestica | 81.56 | 3e-172 | 485 |
| LLPS-Dio-1766 | Dipodomys ordii | 81.32 | 2e-166 | 470 |
| LLPS-Tut-0922 | Tursiops truncatus | 81.27 | 7e-152 | 432 |
| LLPS-Ova-1539 | Ovis aries | 81.21 | 1e-171 | 485 |
| LLPS-Caj-0255 | Callithrix jacchus | 81.21 | 4e-171 | 482 |
| LLPS-Anc-1947 | Anolis carolinensis | 81.21 | 3e-174 | 490 |
| LLPS-Orc-1907 | Oryctolagus cuniculus | 81.21 | 2e-171 | 483 |
| LLPS-Paa-0583 | Papio anubis | 80.85 | 6e-171 | 482 |
| LLPS-Gog-2035 | Gorilla gorilla | 80.85 | 6e-171 | 482 |
| LLPS-Chs-1298 | Chlorocebus sabaeus | 80.85 | 6e-171 | 482 |
| LLPS-Maf-3014 | Macaca fascicularis | 80.85 | 6e-171 | 482 |
| LLPS-Poa-2398 | Pongo abelii | 80.85 | 6e-171 | 482 |
| LLPS-Rhb-2622 | Rhinopithecus bieti | 80.85 | 6e-171 | 482 |
| LLPS-Man-2933 | Macaca nemestrina | 80.85 | 6e-171 | 482 |
| LLPS-Pat-2150 | Pan troglodytes | 80.85 | 6e-171 | 482 |
| LLPS-Hos-0715 | Homo sapiens | 80.85 | 6e-171 | 482 |
| LLPS-Aim-0099 | Ailuropoda melanoleuca | 80.66 | 2e-166 | 470 |
| LLPS-Ict-2393 | Ictidomys tridecemlineatus | 80.57 | 2e-169 | 478 |
| LLPS-Sus-0690 | Sus scrofa | 80.5 | 5e-171 | 482 |
| LLPS-Caf-0055 | Canis familiaris | 80.5 | 5e-171 | 482 |
| LLPS-Fec-3024 | Felis catus | 80.5 | 7e-169 | 481 |
| LLPS-Cap-3458 | Cavia porcellus | 80.36 | 3e-165 | 467 |
| LLPS-Loa-2293 | Loxodonta africana | 80.22 | 6e-166 | 469 |
| LLPS-Myl-2919 | Myotis lucifugus | 80.21 | 8e-171 | 481 |
| LLPS-Mup-1705 | Mustela putorius furo | 80.14 | 2e-167 | 473 |
| LLPS-Ere-0700 | Erinaceus europaeus | 80.14 | 2e-167 | 473 |
| LLPS-Ran-4465 | Rattus norvegicus | 80.14 | 8e-171 | 481 |
| LLPS-Mum-3706 | Mus musculus | 80.14 | 8e-171 | 481 |
| LLPS-Eqc-2669 | Equus caballus | 80.14 | 3e-170 | 480 |
| LLPS-Otg-1763 | Otolemur garnettii | 80.14 | 2e-170 | 481 |
| LLPS-Mea-0838 | Mesocricetus auratus | 79.79 | 2e-167 | 473 |
| LLPS-Cea-4320 | Cercocebus atys | 79.43 | 1e-166 | 471 |
| LLPS-Nol-4091 | Nomascus leucogenys | 79.43 | 1e-166 | 471 |
| LLPS-Ora-2232 | Ornithorhynchus anatinus | 79.38 | 4e-152 | 434 |
| LLPS-Scm-0160 | Scophthalmus maximus | 78.78 | 2e-170 | 481 |
| LLPS-Pes-3499 | Pelodiscus sinensis | 78.7 | 4e-162 | 459 |
| LLPS-Asm-1875 | Astyanax mexicanus | 77.3 | 2e-162 | 460 |
| LLPS-Icp-1325 | Ictalurus punctatus | 74.82 | 6e-155 | 441 |
| LLPS-Dar-3028 | Danio rerio | 74.39 | 2e-153 | 439 |
| LLPS-Drm-0389 | Drosophila melanogaster | 59.35 | 1e-125 | 367 |
| LLPS-Cii-0086 | Ciona intestinalis | 55.91 | 6e-110 | 327 |
| LLPS-Cae-1407 | Caenorhabditis elegans | 53.55 | 6e-101 | 304 |
| LLPS-Cis-2038 | Ciona savignyi | 51.24 | 5e-101 | 304 |
| LLPS-Abg-1951 | Absidia glauca | 44.17 | 5e-80 | 250 |
| LLPS-Spr-0539 | Sporisorium reilianum | 41.94 | 4e-28 | 115 |
| LLPS-Put-1021 | Puccinia triticina | 39.17 | 2e-22 | 98.6 |
| LLPS-Cogr-0686 | Colletotrichum graminicola | 39.11 | 6e-64 | 208 |
| LLPS-Gag-1172 | Gaeumannomyces graminis | 38.06 | 2e-60 | 199 |
| LLPS-Beb-1301 | Beauveria bassiana | 37.64 | 2e-62 | 204 |
| LLPS-Mel-1025 | Melampsora laricipopulina | 37.59 | 4e-53 | 181 |
| LLPS-Crn-1470 | Cryptococcus neoformans | 37.5 | 3e-25 | 108 |
| LLPS-Map-0667 | Magnaporthe poae | 37.27 | 2e-61 | 202 |
| LLPS-Pyt-0873 | Pyrenophora teres | 37.22 | 3e-58 | 194 |
| LLPS-Ved-1032 | Verticillium dahliae | 36.9 | 2e-58 | 194 |
| LLPS-Pytr-1180 | Pyrenophora triticirepentis | 36.84 | 6e-59 | 196 |
| LLPS-Usm-1406 | Ustilago maydis | 36.8 | 6e-23 | 100 |
| LLPS-Fuo-1023 | Fusarium oxysporum | 36.6 | 2e-55 | 187 |
| LLPS-Fuv-1551 | Fusarium verticillioides | 36.23 | 1e-55 | 187 |
| LLPS-Phn-1409 | Phaeosphaeria nodorum | 36.04 | 3e-51 | 184 |
| LLPS-Trv-1603 | Trichoderma virens | 35.93 | 3e-59 | 196 |
| LLPS-Zyt-0457 | Zymoseptoria tritici | 35.6 | 5e-53 | 180 |
| LLPS-Trr-1265 | Trichoderma reesei | 35.56 | 3e-58 | 194 |
| LLPS-Lem-1304 | Leptosphaeria maculans | 35.34 | 8e-56 | 187 |
| LLPS-Cus-1812 | Cucumis sativus | 35.27 | 3e-50 | 174 |
| LLPS-Blg-1504 | Blumeria graminis | 35.16 | 3e-60 | 199 |
| LLPS-Asf-1581 | Aspergillus flavus | 34.81 | 1e-56 | 190 |
| LLPS-Asc-0098 | Aspergillus clavatus | 34.07 | 2e-50 | 173 |
| LLPS-Miv-0865 | Microbotryum violaceum | 33.82 | 1e-16 | 83.2 |
| LLPS-Via-1021 | Vigna angularis | 33.8 | 1e-52 | 181 |
| LLPS-Orbr-0678 | Oryza brachyantha | 33.67 | 2e-50 | 174 |
| LLPS-Dos-1509 | Dothistroma septosporum | 33.58 | 9e-52 | 177 |
| LLPS-Ast-0585 | Aspergillus terreus | 33.46 | 4e-51 | 175 |
| LLPS-Sei-0884 | Setaria italica | 33.45 | 1e-46 | 166 |
| LLPS-Brn-1392 | Brassica napus | 33.45 | 3e-47 | 166 |
| LLPS-Bro-0821 | Brassica oleracea | 33.45 | 1e-45 | 162 |
| LLPS-Coc-1524 | Corchorus capsularis | 33.33 | 1e-41 | 151 |
| LLPS-Ors-0988 | Oryza sativa | 33.33 | 5e-33 | 126 |
| LLPS-Glm-1729 | Glycine max | 33.1 | 4e-50 | 174 |
| LLPS-Nef-0479 | Neosartorya fischeri | 32.96 | 1e-48 | 168 |
| LLPS-Met-0111 | Medicago truncatula | 32.86 | 3e-48 | 169 |
| LLPS-Thc-0460 | Theobroma cacao | 32.86 | 8e-47 | 167 |
| LLPS-Ori-1664 | Oryza indica | 32.86 | 7e-44 | 157 |
| LLPS-Org-0207 | Oryza glaberrima | 32.86 | 7e-44 | 157 |
| LLPS-Tra-0086 | Triticum aestivum | 32.66 | 5e-40 | 147 |
| LLPS-Scs-0110 | Sclerotinia sclerotiorum | 32.6 | 8e-41 | 147 |
| LLPS-Mao-1143 | Magnaporthe oryzae | 32.53 | 4e-37 | 138 |
| LLPS-Amt-1614 | Amborella trichopoda | 32.5 | 7e-47 | 165 |
| LLPS-Yal-1069 | Yarrowia lipolytica | 32.46 | 3e-35 | 133 |
| LLPS-Phv-2085 | Phaseolus vulgaris | 32.4 | 3e-49 | 171 |
| LLPS-Pot-1038 | Populus trichocarpa | 32.38 | 4e-49 | 171 |
| LLPS-Brr-0624 | Brassica rapa | 32.38 | 3e-46 | 164 |
| LLPS-Brd-0470 | Brachypodium distachyon | 32.3 | 1e-42 | 154 |
| LLPS-Dac-0260 | Daucus carota | 32.3 | 9e-50 | 172 |
| LLPS-Prp-0619 | Prunus persica | 32.3 | 2e-50 | 174 |
| LLPS-Hea-2700 | Helianthus annuus | 32.29 | 1e-50 | 175 |
| LLPS-Sot-1176 | Solanum tuberosum | 32.08 | 2e-50 | 174 |
| LLPS-Zem-2285 | Zea mays | 32.08 | 8e-46 | 162 |
| LLPS-Sob-0366 | Sorghum bicolor | 32.08 | 9e-45 | 159 |
| LLPS-Mua-2416 | Musa acuminata | 32.07 | 4e-45 | 160 |
| LLPS-Nia-0014 | Nicotiana attenuata | 32.04 | 1e-47 | 173 |
| LLPS-Viv-1389 | Vitis vinifera | 31.96 | 3e-47 | 166 |
| LLPS-Sol-2406 | Solanum lycopersicum | 31.74 | 2e-49 | 172 |
| LLPS-Orgl-0561 | Oryza glumaepatula | 31.4 | 2e-37 | 139 |
| LLPS-Orni-1671 | Oryza nivara | 31.4 | 2e-37 | 139 |
| LLPS-Orb-0390 | Oryza barthii | 31.4 | 2e-37 | 139 |
| LLPS-Orr-0644 | Oryza rufipogon | 31.4 | 2e-37 | 139 |
| LLPS-Sem-1540 | Selaginella moellendorffii | 31.34 | 7e-45 | 159 |
| LLPS-Mae-2085 | Manihot esculenta | 31.14 | 4e-45 | 160 |
| LLPS-Asfu-1140 | Aspergillus fumigatus | 31.12 | 2e-44 | 158 |
| LLPS-Php-1657 | Physcomitrella patens | 31.03 | 3e-44 | 158 |
| LLPS-Gor-1136 | Gossypium raimondii | 30.93 | 1e-45 | 162 |
| LLPS-Asn-0768 | Aspergillus nidulans | 30.77 | 2e-49 | 174 |
| LLPS-Vir-1391 | Vigna radiata | 30.49 | 6e-29 | 115 |
| LLPS-Lep-0218 | Leersia perrieri | 30.49 | 7e-38 | 141 |
| LLPS-Arl-1504 | Arabidopsis lyrata | 30.25 | 6e-44 | 157 |
| LLPS-Art-2114 | Arabidopsis thaliana | 30.25 | 1e-40 | 150 |
| LLPS-Scp-1522 | Schizosaccharomyces pombe | 29.8 | 3e-25 | 106 |
| LLPS-Sac-0429 | Saccharomyces cerevisiae | 28.74 | 2e-29 | 117 |
| LLPS-Scj-1077 | Schizosaccharomyces japonicus | 28.41 | 7e-25 | 105 |
| LLPS-Asg-0334 | Ashbya gossypii | 28.31 | 6e-31 | 122 |
| LLPS-Orp-1694 | Oryza punctata | 28.21 | 2e-27 | 113 |
| LLPS-Kop-0891 | Komagataella pastoris | 26.84 | 3e-26 | 108 |