LLPS-Mel-1025
MELLADRAFT_34510
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | F-actin-capping protein subunit alpha |
| Gene Name: | MELLADRAFT_34510 |
| Ensembl Gene: | MELLADRAFT_34510 |
| Ensembl Protein: | EGG09139 |
| Organism: | Melampsora laricipopulina |
| Taxa ID: | 747676 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EGG09139 | EGG09139 |
| UniProt | F4REQ0, F4REQ0_MELLP | |
| GeneBank | GL883098 | EGG09139.1 |
| RefSeq | XM_007407437.1 | XP_007407499.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MEHEPSLEEK ISVASNFILQ SPPGEVNDVF NDVRPIVGDD AELENGLLPA LSQYNTEQLT 60 61 LVELPNAKIP AMICEAAKLN EGIENLYMDP NSSQTFIFDH LRLTVKDVKA YTPKKDTIEE 120 121 TRFEISNQAE KYVKEHYQGG VWKVSNEVED EEKKFQLYIV GNKYNPGNYW TGRWRSIYEI 180 181 DLTSGTVKGQ IQVNVHYYEQ GNVSLSSSFL TNSCSGSGSV TASQVIKSIS QAETAYQKSV 240 241 NLAYMELGDD TFKQLRRALP VTKQKIDWNN IKTKIVFNDK 280 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAACACG AACCAAGTTT AGAAGAAAAG ATTTCCGTGG CTTCAAACTT TATACTACAA 60 61 TCACCACCTG GAGAAGTGAA TGATGTATTC AATGATGTAA GACCTATTGT AGGAGACGAT 120 121 GCAGAACTTG AAAATGGTTT ACTTCCTGCA CTTTCACAAT ATAATACTGA ACAACTCACT 180 181 TTAGTCGAAT TACCCAATGC GAAAATCCCA GCGATGATTT GTGAAGCAGC CAAATTAAAT 240 241 GAAGGAATTG AAAACCTTTA TATGGATCCA AATTCATCAC AAACGTTTAT TTTTGATCAT 300 301 TTGAGACTTA CTGTCAAAGA TGTTAAAGCT TATACACCGA AAAAAGATAC GATTGAAGAA 360 361 ACTCGATTTG AGATTTCAAA TCAAGCCGAG AAATATGTTA AAGAACATTA TCAAGGTGGT 420 421 GTTTGGAAAG TTTCAAATGA AGTAGAAGAT GAAGAAAAGA AATTTCAATT ATATATTGTG 480 481 GGTAACAAAT ATAACCCAGG AAATTATTGG ACGGGACGAT GGCGTAGCAT ATACGAAATT 540 541 GATCTTACTT CAGGTACTGT TAAGGGGCAA ATCCAAGTCA ATGTACACTA TTACGAGCAA 600 601 GGAAATGTAA GTCTCTCATC ATCTTTTCTT ACAAACTCCT GTTCAGGTTC AGGTTCAGTA 660 661 ACAGCAAGTC AAGTGATCAA ATCGATCTCA CAAGCAGAAA CAGCGTATCA AAAATCAGTG 720 721 AATTTAGCTT ATATGGAACT GGGTGATGAT ACTTTTAAAC AACTTAGAAG AGCTTTACCA 780 781 GTCACCAAAC AAAAGATTGA TTGGAATAAT ATCAAGACTA AGATTGTGTT TAATGATAAA 840 841 TAA 843 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | F-actin capping protein complex | |
Molecular Function | Actin binding | |
Biological Process | Barbed-end actin filament capping |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Put-1021 | Puccinia triticina | 62.7 | 7e-47 | 164 |
| LLPS-Crn-1470 | Cryptococcus neoformans | 47.11 | 3e-30 | 122 |
| LLPS-Abg-1951 | Absidia glauca | 45.35 | 5e-71 | 226 |
| LLPS-Miv-0865 | Microbotryum violaceum | 43.59 | 1e-27 | 114 |
| LLPS-Usm-1406 | Ustilago maydis | 40.0 | 4e-20 | 92.4 |
| LLPS-Spr-0539 | Sporisorium reilianum | 39.17 | 4e-20 | 92.4 |
| LLPS-Xet-3734 | Xenopus tropicalis | 38.55 | 9e-52 | 177 |
| LLPS-Dar-3028 | Danio rerio | 38.46 | 1e-49 | 172 |
| LLPS-Cap-3458 | Cavia porcellus | 38.18 | 2e-50 | 173 |
| LLPS-Lac-0386 | Latimeria chalumnae | 38.06 | 3e-47 | 165 |
| LLPS-Ran-4465 | Rattus norvegicus | 37.82 | 3e-50 | 173 |
| LLPS-Ova-1539 | Ovis aries | 37.82 | 3e-50 | 174 |
| LLPS-Mum-3706 | Mus musculus | 37.82 | 3e-50 | 173 |
| LLPS-Sah-0136 | Sarcophilus harrisii | 37.82 | 5e-51 | 175 |
| LLPS-Anc-1947 | Anolis carolinensis | 37.82 | 2e-50 | 174 |
| LLPS-Mod-2334 | Monodelphis domestica | 37.82 | 6e-51 | 175 |
| LLPS-Ict-2393 | Ictidomys tridecemlineatus | 37.68 | 1e-49 | 172 |
| LLPS-Ere-0700 | Erinaceus europaeus | 37.45 | 5e-47 | 165 |
| LLPS-Caj-0255 | Callithrix jacchus | 37.45 | 5e-49 | 170 |
| LLPS-Sus-0690 | Sus scrofa | 37.45 | 6e-50 | 172 |
| LLPS-Ved-1032 | Verticillium dahliae | 37.45 | 2e-51 | 176 |
| LLPS-Caf-0055 | Canis familiaris | 37.45 | 6e-50 | 172 |
| LLPS-Eqc-2669 | Equus caballus | 37.45 | 6e-50 | 172 |
| LLPS-Otg-1763 | Otolemur garnettii | 37.45 | 6e-50 | 172 |
| LLPS-Orc-1907 | Oryctolagus cuniculus | 37.45 | 2e-49 | 171 |
| LLPS-Fec-3024 | Felis catus | 37.45 | 2e-48 | 171 |
| LLPS-Fud-2366 | Fukomys damarensis | 37.36 | 1e-47 | 166 |
| LLPS-Leo-2179 | Lepisosteus oculatus | 37.32 | 1e-51 | 177 |
| LLPS-Bot-1899 | Bos taurus | 37.22 | 3e-47 | 166 |
| LLPS-Scf-0386 | Scleropages formosus | 37.17 | 2e-48 | 169 |
| LLPS-Aon-2469 | Aotus nancymaae | 37.16 | 1e-44 | 159 |
| LLPS-Paa-0583 | Papio anubis | 37.09 | 8e-49 | 169 |
| LLPS-Gog-2035 | Gorilla gorilla | 37.09 | 8e-49 | 169 |
| LLPS-Maf-3014 | Macaca fascicularis | 37.09 | 8e-49 | 169 |
| LLPS-Chs-1298 | Chlorocebus sabaeus | 37.09 | 8e-49 | 169 |
| LLPS-Gaga-2783 | Gallus gallus | 37.09 | 2e-49 | 171 |
| LLPS-Tag-3045 | Taeniopygia guttata | 37.09 | 3e-49 | 171 |
| LLPS-Poa-2398 | Pongo abelii | 37.09 | 8e-49 | 169 |
| LLPS-Rhb-2622 | Rhinopithecus bieti | 37.09 | 8e-49 | 169 |
| LLPS-Pat-2150 | Pan troglodytes | 37.09 | 8e-49 | 169 |
| LLPS-Hos-0715 | Homo sapiens | 37.09 | 8e-49 | 169 |
| LLPS-Man-2933 | Macaca nemestrina | 37.09 | 8e-49 | 169 |
| LLPS-Anp-0259 | Anas platyrhynchos | 37.08 | 8e-48 | 167 |
| LLPS-Fia-2312 | Ficedula albicollis | 37.04 | 6e-48 | 167 |
| LLPS-Urm-3272 | Ursus maritimus | 36.98 | 2e-47 | 165 |
| LLPS-Xim-0796 | Xiphophorus maculatus | 36.96 | 9e-50 | 172 |
| LLPS-Icp-1325 | Ictalurus punctatus | 36.94 | 1e-48 | 169 |
| LLPS-Myl-2919 | Myotis lucifugus | 36.84 | 4e-47 | 165 |
| LLPS-Aim-0099 | Ailuropoda melanoleuca | 36.84 | 4e-47 | 165 |
| LLPS-Pap-3969 | Pan paniscus | 36.84 | 8e-47 | 164 |
| LLPS-Scm-0160 | Scophthalmus maximus | 36.76 | 7e-54 | 182 |
| LLPS-Loa-2293 | Loxodonta africana | 36.7 | 7e-45 | 159 |
| LLPS-Beb-1301 | Beauveria bassiana | 36.64 | 3e-50 | 173 |
| LLPS-Mal-2848 | Mandrillus leucophaeus | 36.6 | 4e-46 | 162 |
| LLPS-Mam-1704 | Macaca mulatta | 36.6 | 1e-45 | 161 |
| LLPS-Meg-2541 | Meleagris gallopavo | 36.6 | 9e-47 | 164 |
| LLPS-Gaa-0666 | Gasterosteus aculeatus | 36.33 | 1e-49 | 171 |
| LLPS-Dio-1766 | Dipodomys ordii | 36.23 | 1e-44 | 158 |
| LLPS-Orl-0586 | Oryzias latipes | 36.23 | 2e-50 | 174 |
| LLPS-Pof-3335 | Poecilia formosa | 36.23 | 3e-50 | 173 |
| LLPS-Tar-1782 | Takifugu rubripes | 36.13 | 1e-52 | 179 |
| LLPS-Tut-0922 | Tursiops truncatus | 36.09 | 1e-35 | 134 |
| LLPS-Drm-0389 | Drosophila melanogaster | 35.97 | 1e-50 | 174 |
| LLPS-Trr-1265 | Trichoderma reesei | 35.96 | 2e-48 | 168 |
| LLPS-Cea-4320 | Cercocebus atys | 35.77 | 2e-45 | 160 |
| LLPS-Nol-4091 | Nomascus leucogenys | 35.77 | 1e-45 | 161 |
| LLPS-Cas-1795 | Carlito syrichta | 35.65 | 5e-35 | 132 |
| LLPS-Asm-1875 | Astyanax mexicanus | 35.64 | 3e-47 | 165 |
| LLPS-Trv-1603 | Trichoderma virens | 35.58 | 1e-47 | 166 |
| LLPS-Pes-3499 | Pelodiscus sinensis | 35.53 | 1e-42 | 153 |
| LLPS-Mup-1705 | Mustela putorius furo | 35.48 | 6e-46 | 162 |
| LLPS-Mea-0838 | Mesocricetus auratus | 35.48 | 1e-45 | 161 |
| LLPS-Ten-0097 | Tetraodon nigroviridis | 35.34 | 5e-50 | 172 |
| LLPS-Cae-1407 | Caenorhabditis elegans | 35.23 | 3e-43 | 155 |
| LLPS-Orn-2165 | Oreochromis niloticus | 35.21 | 3e-48 | 168 |
| LLPS-Pyt-0873 | Pyrenophora teres | 35.09 | 6e-47 | 164 |
| LLPS-Gag-1172 | Gaeumannomyces graminis | 35.06 | 1e-46 | 163 |
| LLPS-Cii-0086 | Ciona intestinalis | 35.06 | 3e-40 | 147 |
| LLPS-Map-0667 | Magnaporthe poae | 34.93 | 2e-48 | 168 |
| LLPS-Cogr-0686 | Colletotrichum graminicola | 34.83 | 3e-48 | 167 |
| LLPS-Fuv-1551 | Fusarium verticillioides | 34.81 | 1e-47 | 166 |
| LLPS-Dac-0260 | Daucus carota | 34.51 | 9e-42 | 151 |
| LLPS-Fuo-1023 | Fusarium oxysporum | 34.44 | 3e-47 | 165 |
| LLPS-Pytr-1180 | Pyrenophora triticirepentis | 34.34 | 1e-46 | 163 |
| LLPS-Ora-2232 | Ornithorhynchus anatinus | 34.32 | 2e-37 | 139 |
| LLPS-Cis-2038 | Ciona savignyi | 34.19 | 1e-40 | 148 |
| LLPS-Nef-0479 | Neosartorya fischeri | 33.97 | 1e-39 | 145 |
| LLPS-Asc-0098 | Aspergillus clavatus | 33.83 | 4e-40 | 146 |
| LLPS-Ast-0585 | Aspergillus terreus | 33.59 | 9e-39 | 142 |
| LLPS-Lem-1304 | Leptosphaeria maculans | 33.58 | 5e-41 | 149 |
| LLPS-Blg-1504 | Blumeria graminis | 33.58 | 7e-40 | 145 |
| LLPS-Phn-1409 | Phaeosphaeria nodorum | 33.46 | 1e-36 | 143 |
| LLPS-Brd-0470 | Brachypodium distachyon | 33.45 | 6e-32 | 125 |
| LLPS-Zyt-0457 | Zymoseptoria tritici | 33.33 | 9e-37 | 137 |
| LLPS-Asfu-1140 | Aspergillus fumigatus | 33.21 | 1e-39 | 145 |
| LLPS-Scp-1522 | Schizosaccharomyces pombe | 33.2 | 3e-31 | 122 |
| LLPS-Asf-1581 | Aspergillus flavus | 33.09 | 9e-43 | 153 |
| LLPS-Nia-0014 | Nicotiana attenuata | 32.86 | 9e-38 | 145 |
| LLPS-Sac-0429 | Saccharomyces cerevisiae | 32.68 | 2e-30 | 120 |
| LLPS-Yal-1069 | Yarrowia lipolytica | 32.56 | 2e-32 | 125 |
| LLPS-Tra-0086 | Triticum aestivum | 32.53 | 3e-32 | 126 |
| LLPS-Sei-0884 | Setaria italica | 32.5 | 4e-32 | 127 |
| LLPS-Sol-2406 | Solanum lycopersicum | 32.38 | 5e-37 | 139 |
| LLPS-Orbr-0678 | Oryza brachyantha | 32.28 | 2e-34 | 132 |
| LLPS-Zem-2285 | Zea mays | 32.17 | 2e-31 | 124 |
| LLPS-Sob-0366 | Sorghum bicolor | 32.17 | 2e-31 | 124 |
| LLPS-Scs-0110 | Sclerotinia sclerotiorum | 32.08 | 4e-34 | 129 |
| LLPS-Prp-0619 | Prunus persica | 32.06 | 1e-33 | 130 |
| LLPS-Ori-1664 | Oryza indica | 32.03 | 7e-32 | 125 |
| LLPS-Org-0207 | Oryza glaberrima | 32.03 | 7e-32 | 125 |
| LLPS-Ors-0988 | Oryza sativa | 32.0 | 7e-21 | 92.8 |
| LLPS-Dos-1509 | Dothistroma septosporum | 31.72 | 1e-39 | 145 |
| LLPS-Pot-1038 | Populus trichocarpa | 31.71 | 2e-34 | 132 |
| LLPS-Cus-1812 | Cucumis sativus | 31.69 | 5e-35 | 134 |
| LLPS-Met-0111 | Medicago truncatula | 31.67 | 6e-37 | 139 |
| LLPS-Sot-1176 | Solanum tuberosum | 31.67 | 3e-36 | 137 |
| LLPS-Mua-2416 | Musa acuminata | 31.58 | 4e-31 | 123 |
| LLPS-Glm-1589 | Glycine max | 31.43 | 5e-34 | 131 |
| LLPS-Brn-1392 | Brassica napus | 31.34 | 8e-36 | 135 |
| LLPS-Bro-0821 | Brassica oleracea | 31.34 | 4e-35 | 134 |
| LLPS-Hea-2700 | Helianthus annuus | 31.32 | 9e-35 | 133 |
| LLPS-Phv-2085 | Phaseolus vulgaris | 31.29 | 3e-33 | 129 |
| LLPS-Scj-1077 | Schizosaccharomyces japonicus | 31.18 | 1e-27 | 112 |
| LLPS-Vir-1391 | Vigna radiata | 31.16 | 2e-19 | 89.0 |
| LLPS-Asn-0768 | Aspergillus nidulans | 31.14 | 6e-41 | 151 |
| LLPS-Via-1021 | Vigna angularis | 30.94 | 2e-33 | 129 |
| LLPS-Thc-0460 | Theobroma cacao | 30.77 | 5e-32 | 126 |
| LLPS-Viv-1389 | Vitis vinifera | 30.66 | 1e-32 | 127 |
| LLPS-Brr-0624 | Brassica rapa | 30.66 | 1e-35 | 135 |
| LLPS-Mao-1143 | Magnaporthe oryzae | 30.58 | 4e-29 | 117 |
| LLPS-Coc-1524 | Corchorus capsularis | 30.32 | 3e-26 | 109 |
| LLPS-Gor-1136 | Gossypium raimondii | 30.28 | 1e-30 | 122 |
| LLPS-Lep-0218 | Leersia perrieri | 30.11 | 1e-23 | 102 |
| LLPS-Art-2114 | Arabidopsis thaliana | 30.04 | 8e-35 | 134 |
| LLPS-Arl-1504 | Arabidopsis lyrata | 29.97 | 1e-35 | 135 |
| LLPS-Orr-0644 | Oryza rufipogon | 29.89 | 2e-23 | 101 |
| LLPS-Mae-2085 | Manihot esculenta | 29.79 | 6e-30 | 120 |
| LLPS-Sem-1540 | Selaginella moellendorffii | 29.45 | 2e-28 | 115 |
| LLPS-Orgl-0561 | Oryza glumaepatula | 29.18 | 1e-24 | 105 |
| LLPS-Orni-1671 | Oryza nivara | 29.18 | 1e-24 | 105 |
| LLPS-Orb-0390 | Oryza barthii | 29.18 | 1e-24 | 105 |
| LLPS-Amt-1614 | Amborella trichopoda | 28.37 | 7e-29 | 117 |
| LLPS-Php-1657 | Physcomitrella patens | 27.5 | 2e-29 | 118 |
| LLPS-Asg-0334 | Ashbya gossypii | 26.46 | 2e-18 | 86.7 |
| LLPS-Orp-1694 | Oryza punctata | 25.83 | 2e-16 | 81.3 |
| LLPS-Kop-0891 | Komagataella pastoris | 25.48 | 5e-21 | 94.4 |