LLPS-Paa-0583
CAPZA2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | F-actin-capping protein subunit alpha-2; CapZ alpha-2 |
| Gene Name: | CAPZA2 |
| Ensembl Gene: | ENSPANG00000024714.2 |
| Ensembl Protein: | ENSPANP00000021484.1 |
| Organism: | Papio anubis |
| Taxa ID: | 9555 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSPANT00000056694.1 | ENSPANP00000021484.1 |
| Ensembl | ENSPANT00000025924.2 | ENSPANP00000006369.2 |
| Ensembl | ENSPANT00000040419.1 | ENSPANP00000037747.1 |
| UniProt | A0M8R8, CAZA2_PAPAN | |
| GeneBank | DP000233 | AAR16222.1 |
| RefSeq | NM_001168717.1 | NP_001162188.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MADLEEQLSD EEKVRIAAKF IIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNLD 60 61 QFTPVKIEGY EDQVLITEHG DLGNGKFLDP KNRICFKFDH LRKEATDPRP CEVENAVESW 120 121 RTSVETALRA YVKEHYPNGV CTVYGKKIDG QQTIIACIES HQFQAKNFWN GRWRSEWKFT 180 181 ITPSTTQVVG ILKIQVHYYE DGNVQLVSHK DIQDSLTVSN EVQTAKEFIK IVEAAENEYQ 240 241 TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA 286 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGATTGTTG TCAGATACCA GATAGATAAC AAAAAGATGG TGCGTATAGC AGCAAAATTC 60 61 ATCATTCATG CCCCTCCTGG AGAATTTAAT GAGGTTTTTA ATGATGTTCG GTTACTGCTT 120 121 AATAATGACA ATCTTCTCAG GGAAGGAGCA GCCCATGCAT TTGCACAGTA TAACTTGGAC 180 181 CAGTTTACTC CAGTAAAAAT TGAAGGTTAT GAAGATCAGG TATTGATAAC AGAACATGGC 240 241 GACTTGGGAA ATGGAAAGTT TTTGGATCCA AAGAACAGAA TCTGTTTTAA ATTTGATCAC 300 301 TTAAGAAAGG AGGCAACTGA TCCAAGACCC TGTGAAGTAG AAAATGCAGT TGAATCGTGG 360 361 AGAACTTCAG TAGAAACTGC TCTGAGAGCT TATGTAAAAG AACATTACCC GAATGGAGTC 420 421 TGCACTGTGT ATGGCAAAAA AATAGATGGA CAGCAAACCA TTATTGCATG CATAGAAAGC 480 481 CATCAGTTCC AAGCAAAAAA CTTTTGCTGC TGTTTTTATT TTTAA 525 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | F-actin capping protein complex | |
Molecular Function | Actin binding | |
Biological Process | Barbed-end actin filament capping |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Poa-2398 | Pongo abelii | 100.0 | 0.0 | 565 |
| LLPS-Mam-1704 | Macaca mulatta | 100.0 | 0.0 | 539 |
| LLPS-Pat-2150 | Pan troglodytes | 100.0 | 0.0 | 565 |
| LLPS-Pap-3969 | Pan paniscus | 100.0 | 0.0 | 541 |
| LLPS-Hos-0715 | Homo sapiens | 100.0 | 0.0 | 565 |
| LLPS-Man-2933 | Macaca nemestrina | 100.0 | 0.0 | 565 |
| LLPS-Rhb-2622 | Rhinopithecus bieti | 100.0 | 0.0 | 565 |
| LLPS-Mal-2848 | Mandrillus leucophaeus | 100.0 | 0.0 | 539 |
| LLPS-Chs-1298 | Chlorocebus sabaeus | 100.0 | 0.0 | 565 |
| LLPS-Maf-3014 | Macaca fascicularis | 100.0 | 0.0 | 565 |
| LLPS-Gog-2035 | Gorilla gorilla | 100.0 | 0.0 | 565 |
| LLPS-Caj-0255 | Callithrix jacchus | 99.65 | 0.0 | 564 |
| LLPS-Caf-0055 | Canis familiaris | 99.3 | 0.0 | 560 |
| LLPS-Fec-3024 | Felis catus | 99.3 | 0.0 | 558 |
| LLPS-Sus-0690 | Sus scrofa | 99.3 | 0.0 | 560 |
| LLPS-Urm-3272 | Ursus maritimus | 99.27 | 0.0 | 533 |
| LLPS-Eqc-2669 | Equus caballus | 98.95 | 0.0 | 558 |
| LLPS-Otg-1763 | Otolemur garnettii | 98.95 | 0.0 | 558 |
| LLPS-Cas-1795 | Carlito syrichta | 98.74 | 7e-178 | 498 |
| LLPS-Tut-0922 | Tursiops truncatus | 98.33 | 8e-177 | 495 |
| LLPS-Ran-4465 | Rattus norvegicus | 98.25 | 0.0 | 558 |
| LLPS-Ova-1539 | Ovis aries | 98.25 | 0.0 | 555 |
| LLPS-Mum-3706 | Mus musculus | 98.25 | 0.0 | 558 |
| LLPS-Cap-3458 | Cavia porcellus | 98.21 | 0.0 | 540 |
| LLPS-Bot-1899 | Bos taurus | 98.18 | 0.0 | 529 |
| LLPS-Fud-2366 | Fukomys damarensis | 98.17 | 0.0 | 526 |
| LLPS-Ict-2393 | Ictidomys tridecemlineatus | 97.56 | 0.0 | 549 |
| LLPS-Orc-1907 | Oryctolagus cuniculus | 97.55 | 0.0 | 553 |
| LLPS-Aim-0099 | Ailuropoda melanoleuca | 97.13 | 0.0 | 530 |
| LLPS-Mod-2334 | Monodelphis domestica | 96.85 | 0.0 | 546 |
| LLPS-Dio-1766 | Dipodomys ordii | 96.7 | 0.0 | 523 |
| LLPS-Ere-0700 | Erinaceus europaeus | 96.5 | 0.0 | 540 |
| LLPS-Sah-0136 | Sarcophilus harrisii | 96.5 | 0.0 | 545 |
| LLPS-Myl-2919 | Myotis lucifugus | 95.44 | 0.0 | 536 |
| LLPS-Gaga-2783 | Gallus gallus | 95.1 | 0.0 | 541 |
| LLPS-Tag-3045 | Taeniopygia guttata | 95.1 | 0.0 | 540 |
| LLPS-Aon-2469 | Aotus nancymaae | 95.1 | 0.0 | 534 |
| LLPS-Meg-2541 | Meleagris gallopavo | 94.87 | 0.0 | 515 |
| LLPS-Ora-2232 | Ornithorhynchus anatinus | 94.56 | 5e-169 | 477 |
| LLPS-Loa-2293 | Loxodonta africana | 94.12 | 0.0 | 530 |
| LLPS-Anp-0259 | Anas platyrhynchos | 93.62 | 0.0 | 523 |
| LLPS-Cea-4697 | Cercocebus atys | 93.36 | 0.0 | 549 |
| LLPS-Fia-2312 | Ficedula albicollis | 92.31 | 0.0 | 520 |
| LLPS-Anc-1947 | Anolis carolinensis | 91.96 | 0.0 | 531 |
| LLPS-Xet-3734 | Xenopus tropicalis | 90.91 | 0.0 | 524 |
| LLPS-Mup-1705 | Mustela putorius furo | 87.06 | 2e-178 | 501 |
| LLPS-Leo-2179 | Lepisosteus oculatus | 87.06 | 1e-180 | 506 |
| LLPS-Nol-4091 | Nomascus leucogenys | 86.71 | 8e-178 | 499 |
| LLPS-Mea-0838 | Mesocricetus auratus | 86.71 | 1e-178 | 501 |
| LLPS-Pes-3499 | Pelodiscus sinensis | 85.92 | 4e-168 | 474 |
| LLPS-Pof-3335 | Poecilia formosa | 85.31 | 5e-178 | 500 |
| LLPS-Xim-0796 | Xiphophorus maculatus | 85.31 | 5e-177 | 497 |
| LLPS-Lac-0386 | Latimeria chalumnae | 84.78 | 2e-166 | 471 |
| LLPS-Gaa-0666 | Gasterosteus aculeatus | 84.27 | 2e-176 | 496 |
| LLPS-Orl-0586 | Oryzias latipes | 84.27 | 3e-176 | 495 |
| LLPS-Scf-0386 | Scleropages formosus | 83.51 | 6e-170 | 479 |
| LLPS-Tar-1782 | Takifugu rubripes | 82.87 | 1e-173 | 489 |
| LLPS-Scm-0160 | Scophthalmus maximus | 81.82 | 1e-165 | 468 |
| LLPS-Asm-1875 | Astyanax mexicanus | 81.82 | 1e-167 | 473 |
| LLPS-Orn-2165 | Oreochromis niloticus | 81.12 | 2e-168 | 475 |
| LLPS-Ten-0097 | Tetraodon nigroviridis | 80.85 | 6e-166 | 469 |
| LLPS-Icp-1325 | Ictalurus punctatus | 79.02 | 1e-159 | 453 |
| LLPS-Dar-3028 | Danio rerio | 77.62 | 2e-157 | 449 |
| LLPS-Drm-0389 | Drosophila melanogaster | 61.65 | 1e-119 | 352 |
| LLPS-Cii-0086 | Ciona intestinalis | 55.36 | 2e-107 | 320 |
| LLPS-Cae-1407 | Caenorhabditis elegans | 53.17 | 2e-87 | 269 |
| LLPS-Cis-2038 | Ciona savignyi | 52.8 | 7e-100 | 301 |
| LLPS-Abg-1951 | Absidia glauca | 40.14 | 2e-64 | 210 |
| LLPS-Spr-0539 | Sporisorium reilianum | 39.52 | 2e-27 | 114 |
| LLPS-Mel-1025 | Melampsora laricipopulina | 38.18 | 6e-48 | 167 |
| LLPS-Put-1021 | Puccinia triticina | 37.7 | 2e-20 | 92.8 |
| LLPS-Crn-1470 | Cryptococcus neoformans | 36.72 | 2e-22 | 100 |
| LLPS-Zyt-0457 | Zymoseptoria tritici | 36.17 | 2e-48 | 168 |
| LLPS-Ved-1032 | Verticillium dahliae | 36.16 | 8e-54 | 182 |
| LLPS-Cogr-0686 | Colletotrichum graminicola | 36.16 | 4e-56 | 188 |
| LLPS-Beb-1301 | Beauveria bassiana | 36.16 | 1e-53 | 182 |
| LLPS-Usm-1406 | Ustilago maydis | 36.0 | 1e-23 | 102 |
| LLPS-Map-0667 | Magnaporthe poae | 35.53 | 2e-53 | 181 |
| LLPS-Pytr-1180 | Pyrenophora triticirepentis | 35.34 | 1e-50 | 174 |
| LLPS-Gag-1172 | Gaeumannomyces graminis | 35.29 | 7e-53 | 180 |
| LLPS-Trr-1265 | Trichoderma reesei | 34.96 | 6e-53 | 180 |
| LLPS-Lem-1304 | Leptosphaeria maculans | 34.96 | 4e-49 | 170 |
| LLPS-Pyt-0873 | Pyrenophora teres | 34.96 | 2e-49 | 171 |
| LLPS-Cus-1812 | Cucumis sativus | 34.92 | 3e-45 | 160 |
| LLPS-Orbr-0678 | Oryza brachyantha | 34.83 | 1e-47 | 167 |
| LLPS-Sei-0884 | Setaria italica | 34.83 | 5e-44 | 159 |
| LLPS-Asf-1581 | Aspergillus flavus | 34.8 | 9e-50 | 172 |
| LLPS-Ors-0988 | Oryza sativa | 34.78 | 4e-35 | 132 |
| LLPS-Fuv-1551 | Fusarium verticillioides | 34.66 | 3e-51 | 176 |
| LLPS-Org-0207 | Oryza glaberrima | 34.6 | 4e-44 | 157 |
| LLPS-Via-1021 | Vigna angularis | 34.6 | 7e-47 | 165 |
| LLPS-Ori-1664 | Oryza indica | 34.6 | 4e-44 | 157 |
| LLPS-Zem-2285 | Zea mays | 34.48 | 8e-45 | 160 |
| LLPS-Prp-0619 | Prunus persica | 34.46 | 2e-47 | 167 |
| LLPS-Brd-0470 | Brachypodium distachyon | 34.36 | 2e-41 | 151 |
| LLPS-Fuo-1023 | Fusarium oxysporum | 34.3 | 6e-51 | 175 |
| LLPS-Sob-0366 | Sorghum bicolor | 34.14 | 3e-44 | 158 |
| LLPS-Dac-0260 | Daucus carota | 34.12 | 5e-49 | 171 |
| LLPS-Trv-1603 | Trichoderma virens | 34.07 | 4e-53 | 180 |
| LLPS-Phv-2085 | Phaseolus vulgaris | 33.68 | 8e-46 | 162 |
| LLPS-Met-0111 | Medicago truncatula | 33.68 | 2e-43 | 156 |
| LLPS-Blg-1504 | Blumeria graminis | 33.58 | 6e-51 | 175 |
| LLPS-Gor-1136 | Gossypium raimondii | 33.56 | 1e-45 | 162 |
| LLPS-Viv-1389 | Vitis vinifera | 33.33 | 2e-45 | 161 |
| LLPS-Miv-0865 | Microbotryum violaceum | 33.33 | 4e-19 | 90.1 |
| LLPS-Asc-0098 | Aspergillus clavatus | 33.33 | 9e-45 | 158 |
| LLPS-Glm-1729 | Glycine max | 33.33 | 2e-43 | 156 |
| LLPS-Coc-1524 | Corchorus capsularis | 33.22 | 4e-41 | 150 |
| LLPS-Hea-2777 | Helianthus annuus | 32.89 | 6e-45 | 160 |
| LLPS-Thc-0460 | Theobroma cacao | 32.88 | 3e-42 | 155 |
| LLPS-Phn-1409 | Phaeosphaeria nodorum | 32.86 | 1e-42 | 160 |
| LLPS-Ast-0585 | Aspergillus terreus | 32.62 | 2e-43 | 155 |
| LLPS-Nef-0479 | Neosartorya fischeri | 32.6 | 1e-43 | 155 |
| LLPS-Orr-0644 | Oryza rufipogon | 32.53 | 4e-42 | 152 |
| LLPS-Orgl-0561 | Oryza glumaepatula | 32.53 | 4e-42 | 152 |
| LLPS-Orb-0390 | Oryza barthii | 32.53 | 4e-42 | 152 |
| LLPS-Orni-1671 | Oryza nivara | 32.53 | 4e-42 | 152 |
| LLPS-Pot-1038 | Populus trichocarpa | 32.43 | 1e-46 | 164 |
| LLPS-Mua-2416 | Musa acuminata | 32.42 | 3e-41 | 150 |
| LLPS-Amt-1614 | Amborella trichopoda | 32.41 | 5e-45 | 160 |
| LLPS-Php-1657 | Physcomitrella patens | 32.41 | 1e-43 | 157 |
| LLPS-Sem-1262 | Selaginella moellendorffii | 32.29 | 2e-43 | 155 |
| LLPS-Asn-0768 | Aspergillus nidulans | 32.23 | 7e-44 | 159 |
| LLPS-Tra-0086 | Triticum aestivum | 32.07 | 1e-36 | 138 |
| LLPS-Sac-0429 | Saccharomyces cerevisiae | 31.6 | 1e-30 | 121 |
| LLPS-Brr-0624 | Brassica rapa | 31.56 | 4e-42 | 153 |
| LLPS-Mae-2085 | Manihot esculenta | 31.51 | 8e-42 | 152 |
| LLPS-Dos-1509 | Dothistroma septosporum | 31.44 | 1e-43 | 156 |
| LLPS-Mao-1143 | Magnaporthe oryzae | 31.33 | 8e-34 | 129 |
| LLPS-Brn-1392 | Brassica napus | 31.23 | 3e-42 | 153 |
| LLPS-Bro-0821 | Brassica oleracea | 31.16 | 1e-40 | 149 |
| LLPS-Sot-1176 | Solanum tuberosum | 31.16 | 4e-44 | 158 |
| LLPS-Sol-2406 | Solanum lycopersicum | 31.16 | 1e-43 | 157 |
| LLPS-Asfu-1140 | Aspergillus fumigatus | 30.88 | 5e-40 | 146 |
| LLPS-Nia-0014 | Nicotiana attenuata | 30.8 | 7e-41 | 154 |
| LLPS-Art-2114 | Arabidopsis thaliana | 30.56 | 8e-38 | 143 |
| LLPS-Vir-1391 | Vigna radiata | 30.49 | 1e-28 | 114 |
| LLPS-Arl-1504 | Arabidopsis lyrata | 30.48 | 5e-42 | 152 |
| LLPS-Lep-0218 | Leersia perrieri | 30.31 | 1e-35 | 135 |
| LLPS-Kop-0891 | Komagataella pastoris | 30.15 | 5e-26 | 108 |
| LLPS-Scs-0110 | Sclerotinia sclerotiorum | 29.89 | 7e-34 | 129 |
| LLPS-Orp-1694 | Oryza punctata | 29.48 | 5e-32 | 126 |
| LLPS-Yal-1069 | Yarrowia lipolytica | 29.48 | 1e-30 | 121 |
| LLPS-Scp-1522 | Schizosaccharomyces pombe | 29.07 | 1e-21 | 95.9 |
| LLPS-Asg-0334 | Ashbya gossypii | 28.83 | 6e-31 | 122 |
| LLPS-Scj-1077 | Schizosaccharomyces japonicus | 28.79 | 1e-23 | 101 |