DrLLPS - Data resource of LLPS

LLPS-Prp-0619
PRUPE_6G320500

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	F-actin-capping protein subunit alpha
Gene Name:	PRUPE_6G320500, PRUPE_ppa009158mg
Ensembl Gene:	PRUPE_6G320500
Ensembl Protein:	ONI04413
Organism:	Prunus persica
Taxa ID:	3760
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0715	P47755	Client	Stress granule, Postsynaptic density	34.46	2e-47	167

▼ FUNCTION

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ONI04413	ONI04413
UniProt		M5W0D5, M5W0D5_PRUPE
GeneBank	KB639090, CM007656	ONI04413.1, EMJ06826.1
RefSeq	XM_007205565.1	XP_007205627.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MADEEEAELS EKQKKEIAKW FLLNSPPGEI QFVAKDVKAV LNDDVLYEEA ASEAFPLYNK 60 61 SHLISLEMPG RIGDVIVTSF GQLNETEFID PRTAQVAVVD HIKQVCTVVR PALDEELPSA 120 121 YVEEFRCALD AEILKYVDEA YPKGICSVYC GNGKDVEGPG SDFELVVVIS AARHSPQNFC 180 181 NGSWRSIWSI EFKDELQMLE LSGKLQVGAH YFEEGNVQLD AKHECKDTTI FQSSEDSAIA 240 241 IGNIIRQNET EYLSSLEESY SNLPDTTFKD LRRKLPVTRT LFPWQNTLQF SLTRDITKEL 300 301 GIGK 304
Nucleotide CDS Sequence (FASTA)
1 ATGGCGGACG AAGAAGAAGC AGAGCTTAGC GAGAAGCAGA AGAAAGAAAT AGCAAAGTGG 60 61 TTCCTTCTCA ACTCTCCTCC AGGAGAAATC CAATTCGTTG CCAAAGATGT GAAGGCGGTA 120 121 CTGAACGACG ACGTTTTGTA CGAGGAGGCT GCGTCAGAGG CATTCCCACT GTATAACAAA 180 181 TCCCACTTGA TTTCCCTCGA AATGCCCGGT CGAATTGGAG ACGTTATAGT TACATCATTT 240 241 GGACAGCTCA ATGAGACTGA GTTTATTGAT CCCAGGACTG CTCAAGTTGC TGTAGTTGAC 300 301 CACATCAAAC AGGTTTGTAC AGTGGTGAGA CCTGCTCTGG ATGAGGAACT TCCATCAGCA 360 361 TATGTTGAGG AATTTCGGTG TGCTCTCGAT GCAGAAATAC TTAAATATGT TGATGAAGCT 420 421 TATCCAAAGG GAATTTGCTC AGTATACTGT GGCAATGGTA AAGATGTAGA GGGCCCAGGA 480 481 TCTGACTTTG AGCTTGTAGT GGTGATTTCA GCTGCTAGAC ATAGCCCACA AAATTTCTGC 540 541 AACGGTAGTT GGCGCTCGAT ATGGAGCATT GAGTTCAAAG ATGAATTACA AATGCTGGAA 600 601 TTGAGCGGCA AGCTGCAGGT GGGTGCACAC TATTTTGAGG AGGGAAATGT GCAATTAGAT 660 661 GCAAAACATG AATGCAAAGA TACAACAATT TTTCAGTCCT CTGAAGATAG TGCAATTGCC 720 721 ATAGGCAATA TTATTCGCCA AAATGAGACA GAGTACTTGT CATCTCTCGA GGAATCCTAT 780 781 TCAAACTTGC CCGATACTAC TTTCAAGGAT CTTCGAAGAA AGCTTCCAGT TACCCGCACC 840 841 TTATTTCCAT GGCAAAATAC GTTGCAGTTC AGCTTGACAA GAGACATTAC AAAAGAACTT 900 901 GGCATTGGAA AGTGA 915

▼ KEYWORD

ID	Family
KW-0117	Actin capping
KW-0009	Actin-binding
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0008290	Cellular Component	F-actin capping protein complex
GO:0003779	Molecular Function	Actin binding
GO:0051016	Biological Process	Barbed-end actin filament capping

▼ KEGG

pper:18772144

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Glm-1729	Glycine max	79.73	1e-169	480
LLPS-Thc-0460	Theobroma cacao	79.45	4e-170	484
LLPS-Pot-1038	Populus trichocarpa	79.4	7e-174	491
LLPS-Met-0111	Medicago truncatula	79.18	9e-169	478
LLPS-Viv-1389	Vitis vinifera	78.83	5e-178	501
LLPS-Coc-1524	Corchorus capsularis	78.73	2e-149	428
LLPS-Phv-2085	Phaseolus vulgaris	78.38	5e-168	476
LLPS-Cus-1812	Cucumis sativus	78.29	1e-170	483
LLPS-Via-1021	Vigna angularis	78.04	1e-167	475
LLPS-Gor-1136	Gossypium raimondii	77.74	9e-171	484
LLPS-Dac-0260	Daucus carota	77.63	2e-175	495
LLPS-Nia-0014	Nicotiana attenuata	77.03	4e-160	471
LLPS-Mae-2085	Manihot esculenta	75.16	3e-165	469
LLPS-Sot-1176	Solanum tuberosum	74.75	1e-163	465
LLPS-Sol-2377	Solanum lycopersicum	74.09	1e-161	460
LLPS-Ors-0988	Oryza sativa	73.49	1e-108	322
LLPS-Mua-2416	Musa acuminata	73.42	1e-163	465
LLPS-Hea-2777	Helianthus annuus	73.09	8e-159	452
LLPS-Amt-1614	Amborella trichopoda	71.9	2e-164	467
LLPS-Art-2114	Arabidopsis thaliana	71.86	3e-152	439
LLPS-Arl-1504	Arabidopsis lyrata	71.75	3e-159	454
LLPS-Orbr-0678	Oryza brachyantha	71.38	6e-149	427
LLPS-Brr-0624	Brassica rapa	71.1	1e-157	450
LLPS-Vir-1391	Vigna radiata	70.43	4e-116	341
LLPS-Bro-0821	Brassica oleracea	70.13	3e-156	446
LLPS-Brn-1392	Brassica napus	69.81	7e-155	443
LLPS-Sei-0884	Setaria italica	68.63	5e-145	420
LLPS-Ori-1664	Oryza indica	67.11	8e-141	407
LLPS-Org-0207	Oryza glaberrima	67.11	8e-141	407
LLPS-Brd-0470	Brachypodium distachyon	67.0	3e-138	400
LLPS-Sob-0366	Sorghum bicolor	66.55	8e-140	404
LLPS-Tra-0086	Triticum aestivum	66.22	1e-133	389
LLPS-Zem-2285	Zea mays	66.22	4e-138	400
LLPS-Orr-0644	Oryza rufipogon	65.53	7e-132	383
LLPS-Orb-0390	Oryza barthii	65.19	6e-131	381
LLPS-Orni-1671	Oryza nivara	65.19	6e-131	381
LLPS-Orgl-0561	Oryza glumaepatula	65.19	6e-131	381
LLPS-Lep-0218	Leersia perrieri	64.56	8e-132	384
LLPS-Sem-1540	Selaginella moellendorffii	56.85	2e-108	324
LLPS-Php-1657	Physcomitrella patens	55.33	1e-109	328
LLPS-Orp-1694	Oryza punctata	54.65	3e-117	348
LLPS-Put-1021	Puccinia triticina	36.0	3e-10	63.9
LLPS-Chs-1298	Chlorocebus sabaeus	34.46	1e-43	157
LLPS-Maf-3014	Macaca fascicularis	34.46	1e-43	157
LLPS-Gog-2035	Gorilla gorilla	34.46	1e-43	157
LLPS-Paa-0583	Papio anubis	34.46	1e-43	157
LLPS-Man-2933	Macaca nemestrina	34.46	1e-43	157
LLPS-Pat-2150	Pan troglodytes	34.46	1e-43	157
LLPS-Hos-0715	Homo sapiens	34.46	1e-43	157
LLPS-Rhb-2622	Rhinopithecus bieti	34.46	1e-43	157
LLPS-Poa-2398	Pongo abelii	34.46	1e-43	157
LLPS-Usm-1406	Ustilago maydis	34.43	1e-08	59.7
LLPS-Dar-3028	Danio rerio	34.25	3e-40	148
LLPS-Cap-3458	Cavia porcellus	34.25	1e-42	154
LLPS-Aim-0099	Ailuropoda melanoleuca	34.15	1e-39	146
LLPS-Sus-0690	Sus scrofa	34.12	1e-43	156
LLPS-Mum-3706	Mus musculus	34.12	1e-43	156
LLPS-Caj-0255	Callithrix jacchus	34.12	2e-43	156
LLPS-Ran-4465	Rattus norvegicus	34.12	1e-43	156
LLPS-Fec-3024	Felis catus	34.12	3e-42	155
LLPS-Otg-1763	Otolemur garnettii	34.12	1e-43	156
LLPS-Eqc-2669	Equus caballus	34.12	2e-43	156
LLPS-Caf-0055	Canis familiaris	34.12	1e-43	156
LLPS-Gaga-2783	Gallus gallus	34.12	5e-44	157
LLPS-Xet-2225	Xenopus tropicalis	34.12	2e-43	156
LLPS-Ere-0700	Erinaceus europaeus	34.0	4e-41	150
LLPS-Drm-0389	Drosophila melanogaster	33.9	7e-49	171
LLPS-Leo-2179	Lepisosteus oculatus	33.78	1e-42	154
LLPS-Mod-2334	Monodelphis domestica	33.78	5e-43	155
LLPS-Orc-1907	Oryctolagus cuniculus	33.78	7e-44	157
LLPS-Tag-2068	Taeniopygia guttata	33.78	7e-41	149
LLPS-Ict-2393	Ictidomys tridecemlineatus	33.78	3e-43	155
LLPS-Mal-2848	Mandrillus leucophaeus	33.57	2e-40	147
LLPS-Pap-3969	Pan paniscus	33.57	1e-40	148
LLPS-Mam-1704	Macaca mulatta	33.57	8e-40	147
LLPS-Sah-0136	Sarcophilus harrisii	33.45	2e-42	153
LLPS-Icp-1325	Ictalurus punctatus	33.45	4e-39	145
LLPS-Tar-1782	Takifugu rubripes	33.45	5e-48	168
LLPS-Xim-0796	Xiphophorus maculatus	33.45	3e-43	155
LLPS-Anc-1947	Anolis carolinensis	33.45	2e-43	156
LLPS-Ova-1539	Ovis aries	33.33	1e-42	154
LLPS-Lac-0386	Latimeria chalumnae	33.33	2e-40	148
LLPS-Fia-2312	Ficedula albicollis	33.22	1e-40	149
LLPS-Scf-0386	Scleropages formosus	33.21	5e-40	147
LLPS-Urm-3272	Ursus maritimus	33.21	3e-40	147
LLPS-Meg-2541	Meleagris gallopavo	33.21	1e-40	148
LLPS-Orl-0586	Oryzias latipes	33.11	3e-43	155
LLPS-Asm-1875	Astyanax mexicanus	33.11	9e-41	149
LLPS-Gaa-0666	Gasterosteus aculeatus	33.11	7e-44	157
LLPS-Scm-0160	Scophthalmus maximus	33.11	1e-43	157
LLPS-Pof-3335	Poecilia formosa	33.11	2e-43	156
LLPS-Spr-0539	Sporisorium reilianum	33.08	1e-07	56.6
LLPS-Loa-2293	Loxodonta africana	32.98	4e-38	142
LLPS-Aon-2469	Aotus nancymaae	32.97	1e-39	146
LLPS-Fud-2366	Fukomys damarensis	32.86	1e-38	143
LLPS-Bot-1899	Bos taurus	32.86	2e-39	146
LLPS-Dio-3183	Dipodomys ordii	32.77	3e-39	145
LLPS-Orn-2165	Oreochromis niloticus	32.74	3e-39	145
LLPS-Ora-2232	Ornithorhynchus anatinus	32.57	6e-34	130
LLPS-Anp-0259	Anas platyrhynchos	32.53	8e-41	149
LLPS-Myl-2919	Myotis lucifugus	32.5	2e-39	145
LLPS-Pes-3499	Pelodiscus sinensis	32.5	5e-37	139
LLPS-Cea-4320	Cercocebus atys	32.43	7e-39	144
LLPS-Mea-0838	Mesocricetus auratus	32.43	4e-39	145
LLPS-Mup-1705	Mustela putorius furo	32.43	3e-39	145
LLPS-Ten-0097	Tetraodon nigroviridis	32.3	1e-44	159
LLPS-Nol-4091	Nomascus leucogenys	32.09	2e-38	143
LLPS-Abg-1951	Absidia glauca	32.08	8e-41	149
LLPS-Mel-1025	Melampsora laricipopulina	32.06	4e-31	123
LLPS-Mao-1143	Magnaporthe oryzae	31.93	5e-07	54.3
LLPS-Tut-0922	Tursiops truncatus	31.85	1e-34	132
LLPS-Cas-2407	Carlito syrichta	31.76	7e-38	141
LLPS-Crn-1470	Cryptococcus neoformans	31.72	5e-10	63.9
LLPS-Cii-0086	Ciona intestinalis	31.33	5e-39	144
LLPS-Cis-2038	Ciona savignyi	31.19	8e-38	141
LLPS-Ved-1032	Verticillium dahliae	29.89	3e-26	109
LLPS-Cae-1407	Caenorhabditis elegans	29.69	9e-34	130
LLPS-Map-0667	Magnaporthe poae	29.05	7e-29	117
LLPS-Blg-1504	Blumeria graminis	28.99	2e-28	115
LLPS-Trr-1265	Trichoderma reesei	28.99	1e-26	110
LLPS-Fuv-1551	Fusarium verticillioides	28.87	9e-26	108
LLPS-Trv-1603	Trichoderma virens	28.83	4e-26	109
LLPS-Asn-0768	Aspergillus nidulans	28.67	3e-27	114
LLPS-Fuo-1023	Fusarium oxysporum	28.57	2e-25	107
LLPS-Asg-0334	Ashbya gossypii	28.32	3e-14	74.7
LLPS-Pyt-0873	Pyrenophora teres	28.26	3e-26	109
LLPS-Cogr-0686	Colletotrichum graminicola	27.92	2e-26	110
LLPS-Lem-1304	Leptosphaeria maculans	27.9	6e-23	100
LLPS-Beb-1301	Beauveria bassiana	27.72	6e-27	111
LLPS-Nef-0479	Neosartorya fischeri	27.62	4e-23	100
LLPS-Gag-1172	Gaeumannomyces graminis	27.54	1e-26	110
LLPS-Pytr-1180	Pyrenophora triticirepentis	27.54	3e-25	107
LLPS-Ast-0585	Aspergillus terreus	27.37	3e-23	100
LLPS-Scj-1077	Schizosaccharomyces japonicus	27.17	7e-15	76.6
LLPS-Scp-1522	Schizosaccharomyces pombe	27.08	3e-16	80.5
LLPS-Asc-0098	Aspergillus clavatus	26.92	1e-23	102
LLPS-Asfu-1140	Aspergillus fumigatus	26.87	2e-21	95.5
LLPS-Kop-0891	Komagataella pastoris	26.86	2e-14	75.5
LLPS-Sac-0429	Saccharomyces cerevisiae	26.62	3e-16	80.5
LLPS-Miv-0865	Microbotryum violaceum	26.61	1e-07	56.2
LLPS-Asf-1581	Aspergillus flavus	26.22	2e-24	104
LLPS-Dos-1509	Dothistroma septosporum	26.09	4e-23	100
LLPS-Yal-1069	Yarrowia lipolytica	25.62	2e-15	78.2
LLPS-Scs-0110	Sclerotinia sclerotiorum	25.36	8e-17	81.6
LLPS-Phn-1409	Phaeosphaeria nodorum	24.17	6e-18	88.6
LLPS-Zyt-0457	Zymoseptoria tritici	23.88	5e-16	79.7

LLPS-Prp-0619PRUPE_6G320500

Protein Sequence

Nucleotide Sequence

LLPS-Prp-0619
PRUPE_6G320500