DrLLPS - Data resource of LLPS

LLPS-Gog-1067
LSM5

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	U6 snRNA-associated Sm-like protein LSm5
Gene Name:	LSM5
Ensembl Gene:	ENSGGOG00000043469.1
Ensembl Protein:	ENSGGOP00000034494.1
Organism:	Gorilla gorilla
Taxa ID:	9595
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
P-body	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0285	P40089	Client	P-body	51.22	5e-19	80.1

▼ FUNCTION

Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ENSGGOT00000059036.1	ENSGGOP00000034494.1
Ensembl	ENSGGOT00000061082.1	ENSGGOP00000046296.1
UniProt		A0A2I2ZH19, A0A2I2ZH19_GORGO
GeneBank	CABD030050547
RefSeq	XM_004045283.2	XP_004045331.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAANATTNPS QLLPLELVDK CIGSRIHIVM KSDKEIVGTL LGFDDFVNMV LEDVTEFEIT 60 61 PEGRRITKLD QILLNGNNIT MLVPGGEGPE V 91
Nucleotide CDS Sequence (FASTA)
1 ATGGCGGCTA ACGCTACTAC CAACCCGTCG CAGCTGCTGC CGTTAGAGCT TGTGGACAAA 60 61 TGTATAGGAT CAAGAATTCA CATCGTGATG AAGAGTGATA AGGAAATTGT TGGTACTCTT 120 121 CTAGGATTTG ATGACTTTGT CAGTATCCTT TTAAAAGTGA AATCACACCA GAAGGAAGAA 180 181 GGATTACTAA ATTAG 195

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0507	mRNA processing
KW-0508	mRNA splicing
KW-0539	Nucleus
KW-1185	Reference proteome
KW-0687	Ribonucleoprotein
KW-0694	RNA-binding
KW-0747	Spliceosome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0120115	Cellular Component	Lsm2-8 complex
GO:0071005	Cellular Component	U2-type precatalytic spliceosome
GO:0046540	Cellular Component	U4/U6 x U5 tri-snRNP complex
GO:0003723	Molecular Function	RNA binding
GO:0000398	Biological Process	MRNA splicing, via spliceosome
GO:0009617	Biological Process	Response to bacterium

▼ KEGG

ggo:101150838

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Man-0158	Macaca nemestrina	100.0	2e-59	183
LLPS-Loa-3155	Loxodonta africana	100.0	2e-59	183
LLPS-Anp-0652	Anas platyrhynchos	100.0	2e-46	149
LLPS-Pap-2526	Pan paniscus	100.0	2e-59	183
LLPS-Pat-0895	Pan troglodytes	100.0	2e-59	183
LLPS-Hos-1835	Homo sapiens	100.0	2e-59	183
LLPS-Fec-0702	Felis catus	100.0	2e-59	183
LLPS-Fia-2712	Ficedula albicollis	100.0	2e-47	152
LLPS-Orc-1433	Oryctolagus cuniculus	100.0	2e-59	183
LLPS-Rhb-2768	Rhinopithecus bieti	100.0	2e-59	183
LLPS-Otg-2650	Otolemur garnettii	100.0	2e-59	183
LLPS-Pes-1665	Pelodiscus sinensis	100.0	2e-46	149
LLPS-Cap-2955	Cavia porcellus	100.0	2e-59	183
LLPS-Ict-2066	Ictidomys tridecemlineatus	100.0	2e-59	183
LLPS-Nol-1059	Nomascus leucogenys	100.0	2e-59	183
LLPS-Anc-2158	Anolis carolinensis	100.0	5e-33	115
LLPS-Cas-1382	Carlito syrichta	100.0	2e-59	183
LLPS-Cea-0657	Cercocebus atys	100.0	2e-59	183
LLPS-Mea-1035	Mesocricetus auratus	100.0	2e-59	183
LLPS-Mum-3948	Mus musculus	100.0	2e-59	183
LLPS-Maf-2662	Macaca fascicularis	100.0	2e-59	183
LLPS-Fud-0218	Fukomys damarensis	100.0	2e-59	183
LLPS-Caj-1959	Callithrix jacchus	100.0	2e-59	186
LLPS-Dio-1888	Dipodomys ordii	100.0	2e-59	183
LLPS-Bot-1025	Bos taurus	100.0	2e-59	183
LLPS-Tut-0806	Tursiops truncatus	100.0	2e-59	183
LLPS-Paa-1565	Papio anubis	100.0	2e-59	183
LLPS-Mal-1589	Mandrillus leucophaeus	100.0	2e-59	183
LLPS-Ova-0909	Ovis aries	100.0	2e-59	183
LLPS-Myl-2656	Myotis lucifugus	100.0	2e-59	183
LLPS-Aim-2592	Ailuropoda melanoleuca	100.0	2e-59	183
LLPS-Mup-3550	Mustela putorius furo	100.0	5e-59	186
LLPS-Ran-0520	Rattus norvegicus	100.0	2e-59	183
LLPS-Urm-0890	Ursus maritimus	98.9	4e-59	184
LLPS-Meg-0190	Meleagris gallopavo	98.9	4e-59	182
LLPS-Caf-3272	Canis familiaris	98.9	1e-58	181
LLPS-Gaga-0143	Gallus gallus	98.9	4e-59	182
LLPS-Aon-3380	Aotus nancymaae	98.9	6e-59	182
LLPS-Sus-0121	Sus scrofa	98.7	1e-47	153
LLPS-Mam-0114	Macaca mulatta	96.7	6e-58	179
LLPS-Poa-4486	Pongo abelii	96.7	9e-58	179
LLPS-Tag-2207	Taeniopygia guttata	96.7	1e-57	179
LLPS-Lac-2117	Latimeria chalumnae	95.6	2e-57	178
LLPS-Gaa-0324	Gasterosteus aculeatus	95.6	7e-57	177
LLPS-Ten-1182	Tetraodon nigroviridis	95.4	1e-54	171
LLPS-Xet-1921	Xenopus tropicalis	95.12	2e-49	157
LLPS-Ere-0696	Erinaceus europaeus	94.74	6e-31	109
LLPS-Pof-0082	Poecilia formosa	94.51	3e-56	175
LLPS-Dar-0709	Danio rerio	94.51	8e-56	174
LLPS-Leo-1421	Lepisosteus oculatus	94.51	5e-56	174
LLPS-Scf-3471	Scleropages formosus	94.51	2e-56	175
LLPS-Orl-2666	Oryzias latipes	93.41	3e-55	175
LLPS-Icp-1580	Ictalurus punctatus	93.41	1e-55	174
LLPS-Cii-1238	Ciona intestinalis	88.76	2e-50	160
LLPS-Cis-0832	Ciona savignyi	88.37	3e-50	159
LLPS-Tar-1013	Takifugu rubripes	87.95	4e-44	145
LLPS-Eqc-3453	Equus caballus	85.71	3e-47	152
LLPS-Xim-0733	Xiphophorus maculatus	84.62	1e-48	156
LLPS-Asm-1594	Astyanax mexicanus	81.91	2e-45	147
LLPS-Drm-1010	Drosophila melanogaster	81.4	5e-44	144
LLPS-Hea-1511	Helianthus annuus	81.01	5e-41	136
LLPS-Pot-0099	Populus trichocarpa	79.27	2e-41	137
LLPS-Org-1178	Oryza glaberrima	79.03	1e-27	101
LLPS-Viv-0837	Vitis vinifera	79.01	6e-41	136
LLPS-Prp-0937	Prunus persica	79.01	4e-41	136
LLPS-Cus-0567	Cucumis sativus	79.01	7e-41	135
LLPS-Gor-2142	Gossypium raimondii	77.78	6e-40	133
LLPS-Mae-1618	Manihot esculenta	77.78	4e-40	134
LLPS-Coc-0518	Corchorus capsularis	77.78	4e-40	134
LLPS-Thc-0968	Theobroma cacao	77.78	4e-40	134
LLPS-Mua-1049	Musa acuminata	77.78	3e-40	134
LLPS-Met-0170	Medicago truncatula	77.78	4e-40	134
LLPS-Tru-1522	Triticum urartu	77.42	4e-27	100
LLPS-Sem-1325	Selaginella moellendorffii	77.11	3e-40	134
LLPS-Phv-1406	Phaseolus vulgaris	76.47	3e-40	134
LLPS-Via-1005	Vigna angularis	76.47	3e-40	134
LLPS-Vir-0984	Vigna radiata	76.47	3e-40	134
LLPS-Abg-1384	Absidia glauca	76.25	9e-38	127
LLPS-Amt-0758	Amborella trichopoda	75.51	6e-20	81.6
LLPS-Sol-0254	Solanum lycopersicum	75.32	2e-33	127
LLPS-Art-2427	Arabidopsis thaliana	75.31	4e-39	131
LLPS-Glm-0575	Glycine max	75.29	6e-40	133
LLPS-Asn-1165	Aspergillus nidulans	75.0	4e-35	122
LLPS-Sot-0955	Solanum tuberosum	74.42	2e-41	137
LLPS-Arl-1995	Arabidopsis lyrata	74.12	2e-39	132
LLPS-Trr-1271	Trichoderma reesei	73.75	1e-34	119
LLPS-Coo-0296	Colletotrichum orbiculare	73.75	2e-34	119
LLPS-Tum-0199	Tuber melanosporum	73.75	2e-34	119
LLPS-Cae-1122	Caenorhabditis elegans	73.63	1e-44	145
LLPS-Orp-1853	Oryza punctata	73.56	2e-41	137
LLPS-Ors-1347	Oryza sativa	73.56	2e-41	137
LLPS-Orbr-2170	Oryza brachyantha	73.56	2e-41	137
LLPS-Sob-1690	Sorghum bicolor	73.56	3e-41	137
LLPS-Orr-0559	Oryza rufipogon	73.56	2e-41	137
LLPS-Orm-0856	Oryza meridionalis	73.56	2e-41	137
LLPS-Zem-0066	Zea mays	73.56	3e-41	137
LLPS-Orb-1807	Oryza barthii	73.56	2e-41	137
LLPS-Ori-0964	Oryza indica	73.56	2e-41	137
LLPS-Orni-0528	Oryza nivara	73.56	2e-41	137
LLPS-Lep-1120	Leersia perrieri	73.56	3e-41	137
LLPS-Orgl-0233	Oryza glumaepatula	73.56	2e-41	137
LLPS-Brd-1237	Brachypodium distachyon	73.56	2e-41	137
LLPS-Sei-1880	Setaria italica	73.33	3e-41	140
LLPS-Brr-1725	Brassica rapa	73.26	2e-39	132
LLPS-Bro-2383	Brassica oleracea	73.26	2e-39	132
LLPS-Brn-1565	Brassica napus	73.26	2e-39	132
LLPS-Fus-0306	Fusarium solani	72.84	5e-35	120
LLPS-Trv-1108	Trichoderma virens	72.5	5e-34	118
LLPS-Cogr-1131	Colletotrichum graminicola	72.5	2e-34	119
LLPS-Asfu-1082	Aspergillus fumigatus	72.5	5e-34	118
LLPS-Asc-1296	Aspergillus clavatus	72.5	1e-34	120
LLPS-Nec-0441	Neurospora crassa	72.5	9e-35	120
LLPS-Asf-1355	Aspergillus flavus	72.5	2e-34	119
LLPS-Tra-1102	Triticum aestivum	72.41	7e-41	136
LLPS-Php-0590	Physcomitrella patens	72.22	1e-39	135
LLPS-Nef-1335	Neosartorya fischeri	71.67	1e-20	83.6
LLPS-Fuv-0096	Fusarium verticillioides	71.6	2e-34	119
LLPS-Spr-1331	Sporisorium reilianum	71.25	5e-35	121
LLPS-Usm-0548	Ustilago maydis	71.25	3e-35	122
LLPS-Ved-0622	Verticillium dahliae	71.25	4e-33	116
LLPS-Hov-0897	Hordeum vulgare	71.11	2e-40	136
LLPS-Gas-0063	Galdieria sulphuraria	70.51	3e-32	114
LLPS-Dos-0847	Dothistroma septosporum	70.13	2e-29	106
LLPS-Ast-0586	Aspergillus terreus	70.0	3e-33	116
LLPS-Beb-1032	Beauveria bassiana	70.0	3e-32	113
LLPS-Scs-0835	Sclerotinia sclerotiorum	70.0	1e-31	112
LLPS-Zyt-0225	Zymoseptoria tritici	68.83	7e-30	107
LLPS-Gag-0908	Gaeumannomyces graminis	68.75	1e-32	115
LLPS-Map-0932	Magnaporthe poae	68.29	7e-33	115
LLPS-Asni-1218	Aspergillus niger	67.86	6e-18	76.3
LLPS-Osl-0398	Ostreococcus lucimarinus	67.78	6e-36	123
LLPS-Mao-1394	Magnaporthe oryzae	67.5	2e-32	114
LLPS-Miv-0016	Microbotryum violaceum	66.27	6e-30	108
LLPS-Blg-0349	Blumeria graminis	65.85	7e-32	112
LLPS-Pug-0677	Puccinia graminis	65.75	2e-29	108
LLPS-Dac-1866	Daucus carota	64.89	2e-35	122
LLPS-Lem-0416	Leptosphaeria maculans	61.73	7e-26	97.4
LLPS-Ora-2255	Ornithorhynchus anatinus	61.33	6e-28	102
LLPS-Crn-0805	Cryptococcus neoformans	60.98	2e-30	109
LLPS-Scm-3458	Scophthalmus maximus	60.44	2e-25	95.5
LLPS-Phn-0239	Phaeosphaeria nodorum	59.77	1e-24	94.7
LLPS-Yal-0424	Yarrowia lipolytica	59.3	7e-25	95.1
LLPS-Scj-0516	Schizosaccharomyces japonicus	59.21	3e-23	90.9
LLPS-Mod-3518	Monodelphis domestica	57.45	8e-22	87.4
LLPS-Scp-1037	Schizosaccharomyces pombe	56.96	1e-22	89.0
LLPS-Scc-0912	Schizosaccharomyces cryophilus	55.7	4e-22	87.8
LLPS-Pyt-0195	Pyrenophora teres	55.06	6e-22	87.8
LLPS-Kop-0427	Komagataella pastoris	52.7	3e-16	72.4
LLPS-Sac-0285	Saccharomyces cerevisiae	51.22	4e-19	80.1
LLPS-Pytr-1282	Pyrenophora triticirepentis	49.33	4e-11	58.9
LLPS-Asg-0446	Ashbya gossypii	48.1	3e-19	80.5
LLPS-Cym-0422	Cyanidioschyzon merolae	42.35	1e-17	76.6
LLPS-Orn-0058	Oreochromis niloticus	34.67	7e-06	44.7
LLPS-Nia-0082	Nicotiana attenuata	32.97	9e-07	49.3

LLPS-Gog-1067LSM5

Protein Sequence

Nucleotide Sequence

LLPS-Gog-1067
LSM5