DrLLPS - Data resource of LLPS

LLPS-Cog-0938
CGGC5_3844

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase
Gene Name:	CGGC5_3844
Ensembl Gene:	CGGC5_3844
Ensembl Protein:	ELA36577
Organism:	Colletotrichum gloeosporioides
Taxa ID:	1213859
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0953	Q6NVY1	Client	Nucleolus, Postsynaptic density	40.38	5e-72	239

▼ FUNCTION

Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ELA36577	ELA36577
UniProt		L2GD83, L2GD83_COLFN
GeneBank	KB020507	ELA36577.1
RefSeq	XM_007274286.1	XP_007274348.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MPLRAKILGA QASSSAQMST KVPAEFQERR NDDPDDVLFN SLYGLRTIQL NRPKKLNSLN 60 61 ASMIRKILPR LVEWSKSDMA NVVVMKGAGE KAFCAGGDVA ELAKYNLESK DGWKKSSDYF 120 121 ALEYMLDHYI ATYKKPYVAF MDGITMGGGV GLSVHAPFRI ATERTVFAMP ETTIGFFPDV 180 181 GASFFLPRLQ GYIGTYLALT SERLKGVNVF YSGLATHYLH STSLPQLESR LAEIHFEDQD 240 241 SMDKRLKIIA ATLEEYATGL PFDEPMLIAG ELREAIDRCF SRSSIQGIIE SLKAEEGETK 300 301 EWAEKTLDTL HKRSPTAVNV ALKQMRVGRE WGIGKTFQHE HQIATKFMKH PDFSEGVTAL 360 361 LVRKETPKWQ PATLDAVKTQ DVDAFFQKEG DELELLNNRN YSEYPFYFGL PTEKDVKEVV 420 421 IEGQYSPKQV LNKMVKDSNG RQGVKQVVED ILARNTSVND KGRAVWEEGG W 471

Protein Sequence (FASTA)

1     MPLRAKILGA  QASSSAQMST  KVPAEFQERR  NDDPDDVLFN  SLYGLRTIQL  NRPKKLNSLN  60
61    ASMIRKILPR  LVEWSKSDMA  NVVVMKGAGE  KAFCAGGDVA  ELAKYNLESK  DGWKKSSDYF  120
121   ALEYMLDHYI  ATYKKPYVAF  MDGITMGGGV  GLSVHAPFRI  ATERTVFAMP  ETTIGFFPDV  180
181   GASFFLPRLQ  GYIGTYLALT  SERLKGVNVF  YSGLATHYLH  STSLPQLESR  LAEIHFEDQD  240
241   SMDKRLKIIA  ATLEEYATGL  PFDEPMLIAG  ELREAIDRCF  SRSSIQGIIE  SLKAEEGETK  300
301   EWAEKTLDTL  HKRSPTAVNV  ALKQMRVGRE  WGIGKTFQHE  HQIATKFMKH  PDFSEGVTAL  360
361   LVRKETPKWQ  PATLDAVKTQ  DVDAFFQKEG  DELELLNNRN  YSEYPFYFGL  PTEKDVKEVV  420
421   IEGQYSPKQV  LNKMVKDSNG  RQGVKQVVED  ILARNTSVND  KGRAVWEEGG  W  471

▼ KEYWORD

ID	Family
KW-0101	Branched-chain amino acid catabolism
KW-0181	Complete proteome
KW-0378	Hydrolase
KW-0496	Mitochondrion
KW-1185	Reference proteome
KW-0809	Transit peptide

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005739	Cellular Component	Mitochondrion
GO:0003860	Molecular Function	3-hydroxyisobutyryl-CoA hydrolase activity
GO:0006574	Biological Process	Valine catabolic process

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Coo-1542	Colletotrichum orbiculare	75.26	0.0	750
LLPS-Cogr-0909	Colletotrichum graminicola	72.96	0.0	731
LLPS-Zyt-1021	Zymoseptoria tritici	67.05	1e-120	361
LLPS-Fuo-1575	Fusarium oxysporum	65.25	0.0	658
LLPS-Trv-0743	Trichoderma virens	64.88	0.0	620
LLPS-Trr-0720	Trichoderma reesei	64.64	0.0	617
LLPS-Ved-1589	Verticillium dahliae	64.54	0.0	630
LLPS-Fuv-1514	Fusarium verticillioides	64.39	0.0	650
LLPS-Beb-1647	Beauveria bassiana	63.66	0.0	614
LLPS-Fus-0994	Fusarium solani	63.19	0.0	635
LLPS-Mao-1200	Magnaporthe oryzae	61.26	0.0	588
LLPS-Asf-1574	Aspergillus flavus	59.82	0.0	527
LLPS-Gag-1303	Gaeumannomyces graminis	59.29	0.0	563
LLPS-Scs-0876	Sclerotinia sclerotiorum	59.2	0.0	610
LLPS-Ast-1572	Aspergillus terreus	58.42	0.0	545
LLPS-Aso-0894	Aspergillus oryzae	57.66	0.0	545
LLPS-Lem-1245	Leptosphaeria maculans	57.08	8e-178	526
LLPS-Nec-1202	Neurospora crassa	56.63	0.0	546
LLPS-Asc-1135	Aspergillus clavatus	56.62	0.0	532
LLPS-Asfu-1406	Aspergillus fumigatus	56.36	6e-177	516
LLPS-Nef-1525	Neosartorya fischeri	55.98	0.0	528
LLPS-Pytr-0954	Pyrenophora triticirepentis	55.89	2e-180	521
LLPS-Asni-1073	Aspergillus niger	55.49	0.0	524
LLPS-Pyt-1639	Pyrenophora teres	55.46	6e-180	520
LLPS-Dos-1489	Dothistroma septosporum	54.81	3e-179	518
LLPS-Phn-1482	Phaeosphaeria nodorum	54.44	8e-166	483
LLPS-Asn-1050	Aspergillus nidulans	54.28	2e-179	520
LLPS-Tum-1391	Tuber melanosporum	53.94	5e-170	494
LLPS-Blg-0922	Blumeria graminis	53.59	0.0	540
LLPS-Cas-2167	Carlito syrichta	45.72	2e-71	234
LLPS-Cii-2397	Ciona intestinalis	45.08	2e-97	305
LLPS-Drm-1049	Drosophila melanogaster	44.57	2e-91	290
LLPS-Dar-3829	Danio rerio	44.41	8e-92	291
LLPS-Pof-0448	Poecilia formosa	44.41	1e-91	290
LLPS-Pap-4569	Pan paniscus	43.66	1e-66	222
LLPS-Cis-0744	Ciona savignyi	43.62	3e-99	310
LLPS-Gaga-2658	Gallus gallus	43.56	9e-91	288
LLPS-Icp-1799	Ictalurus punctatus	43.45	4e-91	289
LLPS-Scf-2903	Scleropages formosus	43.45	7e-91	288
LLPS-Abg-1463	Absidia glauca	43.32	3e-119	366
LLPS-Meg-0328	Meleagris gallopavo	43.29	2e-91	290
LLPS-Fia-3838	Ficedula albicollis	43.24	3e-81	264
LLPS-Orc-3621	Oryctolagus cuniculus	43.13	2e-79	258
LLPS-Orl-2685	Oryzias latipes	43.06	6e-85	273
LLPS-Xim-2664	Xiphophorus maculatus	43.05	6e-77	253
LLPS-Tag-0074	Taeniopygia guttata	42.97	8e-80	259
LLPS-Yal-0151	Yarrowia lipolytica	42.86	4e-115	354
LLPS-Lac-2939	Latimeria chalumnae	42.61	2e-85	274
LLPS-Xet-2957	Xenopus tropicalis	42.53	1e-85	275
LLPS-Mum-3552	Mus musculus	42.36	8e-85	273
LLPS-Myl-2978	Myotis lucifugus	42.33	1e-81	264
LLPS-Scp-1654	Schizosaccharomyces pombe	42.23	2e-84	273
LLPS-Anp-3164	Anas platyrhynchos	42.05	4e-83	268
LLPS-Gaa-3417	Gasterosteus aculeatus	41.83	6e-92	291
LLPS-Scm-0981	Scophthalmus maximus	41.78	2e-90	287
LLPS-Orn-1447	Oreochromis niloticus	41.6	5e-95	299
LLPS-Ora-3331	Ornithorhynchus anatinus	41.51	5e-18	85.1
LLPS-Cea-1129	Cercocebus atys	41.46	6e-86	275
LLPS-Mal-1900	Mandrillus leucophaeus	41.46	6e-86	275
LLPS-Fec-2804	Felis catus	41.4	4e-75	247
LLPS-Cap-3013	Cavia porcellus	41.38	3e-74	245
LLPS-Leo-3624	Lepisosteus oculatus	41.29	4e-87	278
LLPS-Nol-4001	Nomascus leucogenys	41.21	6e-87	278
LLPS-Pes-1335	Pelodiscus sinensis	41.1	1e-85	275
LLPS-Asm-3282	Astyanax mexicanus	41.05	4e-84	271
LLPS-Anc-1201	Anolis carolinensis	41.0	3e-76	250
LLPS-Paa-4595	Papio anubis	40.92	2e-85	273
LLPS-Put-1348	Puccinia triticina	40.7	2e-92	310
LLPS-Loa-2743	Loxodonta africana	40.66	4e-81	263
LLPS-Poa-0150	Pongo abelii	40.66	5e-85	273
LLPS-Man-3550	Macaca nemestrina	40.65	3e-84	271
LLPS-Mam-1749	Macaca mulatta	40.65	8e-84	270
LLPS-Maf-3130	Macaca fascicularis	40.65	3e-84	271
LLPS-Cae-1991	Caenorhabditis elegans	40.56	1e-84	272
LLPS-Dac-2346	Daucus carota	40.55	3e-79	258
LLPS-Ova-2588	Ovis aries	40.52	1e-71	238
LLPS-Fud-1423	Fukomys damarensis	40.46	1e-74	246
LLPS-Chs-1006	Chlorocebus sabaeus	40.46	3e-76	249
LLPS-Sol-1247	Solanum lycopersicum	40.43	2e-82	266
LLPS-Hos-0953	Homo sapiens	40.38	1e-84	272
LLPS-Pat-4296	Pan troglodytes	40.38	2e-84	272
LLPS-Aon-0536	Aotus nancymaae	40.38	3e-82	266
LLPS-Mod-4328	Monodelphis domestica	40.33	6e-71	236
LLPS-Urm-0656	Ursus maritimus	40.22	2e-83	269
LLPS-Caj-4382	Callithrix jacchus	40.22	4e-83	268
LLPS-Rhb-3883	Rhinopithecus bieti	40.17	3e-75	247
LLPS-Bot-1862	Bos taurus	40.17	2e-69	233
LLPS-Scc-0311	Schizosaccharomyces cryophilus	40.12	3e-71	238
LLPS-Caf-1512	Canis familiaris	40.11	1e-81	264
LLPS-Mup-1465	Mustela putorius furo	40.11	1e-81	265
LLPS-Ten-2922	Tetraodon nigroviridis	40.1	8e-86	275
LLPS-Bro-0818	Brassica oleracea	40.06	1e-83	269
LLPS-Dio-0082	Dipodomys ordii	40.06	3e-81	263
LLPS-Nia-1815	Nicotiana attenuata	40.0	2e-68	231
LLPS-Sus-4180	Sus scrofa	40.0	6e-84	270
LLPS-Ict-3568	Ictidomys tridecemlineatus	39.84	8e-86	275
LLPS-Gog-0230	Gorilla gorilla	39.84	3e-83	268
LLPS-Mea-2210	Mesocricetus auratus	39.74	4e-84	270
LLPS-Mel-1309	Melampsora laricipopulina	39.69	4e-88	285
LLPS-Tru-0333	Triticum urartu	39.63	1e-60	209
LLPS-Ran-4626	Rattus norvegicus	39.58	2e-85	274
LLPS-Brr-2685	Brassica rapa	39.56	7e-85	273
LLPS-Brn-1749	Brassica napus	39.56	7e-85	273
LLPS-Viv-0261	Vitis vinifera	39.41	7e-71	237
LLPS-Pot-1001	Populus trichocarpa	39.34	4e-81	263
LLPS-Sah-2128	Sarcophilus harrisii	39.34	2e-81	264
LLPS-Prp-0021	Prunus persica	39.3	2e-84	271
LLPS-Coc-1911	Corchorus capsularis	39.24	1e-84	273
LLPS-Tar-2589	Takifugu rubripes	39.02	8e-84	271
LLPS-Phv-2462	Phaseolus vulgaris	39.01	4e-81	263
LLPS-Met-1091	Medicago truncatula	38.9	2e-76	251
LLPS-Art-2956	Arabidopsis thaliana	38.83	6e-79	257
LLPS-Sob-2220	Sorghum bicolor	38.74	6e-80	260
LLPS-Tra-2020	Triticum aestivum	38.74	9e-67	226
LLPS-Gas-0425	Galdieria sulphuraria	38.74	2e-73	243
LLPS-Brd-2197	Brachypodium distachyon	38.74	2e-66	226
LLPS-Mua-1661	Musa acuminata	38.69	7e-72	239
LLPS-Via-1371	Vigna angularis	38.63	6e-72	246
LLPS-Gor-2490	Gossypium raimondii	38.57	1e-81	265
LLPS-Zem-1989	Zea mays	38.57	1e-68	231
LLPS-Mae-0366	Manihot esculenta	38.48	2e-78	256
LLPS-Thc-0843	Theobroma cacao	38.42	1e-80	261
LLPS-Php-2169	Physcomitrella patens	38.38	2e-77	254
LLPS-Pug-1348	Puccinia graminis	38.35	8e-88	285
LLPS-Scj-1055	Schizosaccharomyces japonicus	38.3	4e-72	240
LLPS-Arl-2879	Arabidopsis lyrata	38.12	4e-78	255
LLPS-Cus-1927	Cucumis sativus	38.07	2e-70	236
LLPS-Org-2195	Oryza glaberrima	37.91	2e-63	217
LLPS-Orr-2140	Oryza rufipogon	37.91	2e-63	217
LLPS-Orni-0564	Oryza nivara	37.91	2e-63	217
LLPS-Ori-1877	Oryza indica	37.91	2e-63	217
LLPS-Orgl-0494	Oryza glumaepatula	37.91	2e-63	217
LLPS-Lep-0185	Leersia perrieri	37.89	3e-62	214
LLPS-Orbr-2270	Oryza brachyantha	37.7	9e-66	231
LLPS-Vir-1874	Vigna radiata	37.67	5e-54	191
LLPS-Ors-1816	Oryza sativa	37.64	1e-62	215
LLPS-Orb-0421	Oryza barthii	37.64	3e-62	214
LLPS-Hea-1545	Helianthus annuus	37.57	3e-61	211
LLPS-Otg-0273	Otolemur garnettii	37.44	4e-36	138
LLPS-Sei-0243	Setaria italica	37.43	9e-66	223
LLPS-Hov-0146	Hordeum vulgare	37.4	5e-78	256
LLPS-Miv-0680	Microbotryum violaceum	37.22	5e-92	296
LLPS-Eqc-4263	Equus caballus	37.19	8e-72	238
LLPS-Orp-0574	Oryza punctata	37.12	9e-64	218
LLPS-Sot-1237	Solanum tuberosum	37.03	8e-79	257
LLPS-Glm-2563	Glycine max	36.73	2e-77	253
LLPS-Amt-0199	Amborella trichopoda	36.55	3e-38	145
LLPS-Aim-0188	Ailuropoda melanoleuca	36.48	1e-43	159
LLPS-Chc-0825	Chondrus crispus	35.83	3e-58	204
LLPS-Usm-0068	Ustilago maydis	34.85	4e-61	215
LLPS-Spr-0544	Sporisorium reilianum	34.31	5e-61	215
LLPS-Kop-0210	Komagataella pastoris	33.97	2e-74	249
LLPS-Sac-1282	Saccharomyces cerevisiae	33.69	6e-71	240
LLPS-Crn-0044	Cryptococcus neoformans	32.45	6e-55	197
LLPS-Asg-1473	Ashbya gossypii	32.33	9e-64	220
LLPS-Chr-1459	Chlamydomonas reinhardtii	32.08	1e-53	191
LLPS-Sem-1765	Selaginella moellendorffii	32.02	6e-57	199
LLPS-Orm-1432	Oryza meridionalis	31.48	7e-54	191
LLPS-Cym-0712	Cyanidioschyzon merolae	31.4	5e-40	156
LLPS-Osl-0876	Ostreococcus lucimarinus	31.12	2e-43	161

LLPS-Cog-0938CGGC5_3844

Protein Sequence

Nucleotide Sequence

LLPS-Cog-0938
CGGC5_3844