DrLLPS - Data resource of LLPS

LLPS-Ast-1572
ATEG_01986

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase
Gene Name:	ATEG_01986
Ensembl Gene:	ATEG_01986
Ensembl Protein:	EAU36948
Organism:	Aspergillus terreus
Taxa ID:	341663
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-0953	Q6NVY1	Client	Nucleolus, Postsynaptic density	39.83	1e-67	228

▼ FUNCTION

Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	EAU36948	EAU36948
UniProt		Q0CWE8, Q0CWE8_ASPTN
GeneBank	CH476596	EAU36948.1
RefSeq	XM_001211164.1	XP_001211164.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MPLRAKVTNP AFGSTAKMST SPDLPKELPG DEPDDVLFNS LYGVRLIELN RPKKLNSLNG 60 61 SMARKILPRL KEWEKSQLAN VVMVSGAGSK ALCAGGDVAA LALQNEQGPE GQQKSTDFFG 120 121 LEYCLDHTIA TYPKPFISVM DGITMGGGVG LSVHAPFRIA TERTVFAMPE TTIGFFPDVG 180 181 GSFFLPRLDG EVGTYLALTS ERLTGVQTLY AGIATHYLHS SVLSNLTSRL AELVFKDSAS 240 241 LPERLDLVNK TMAEFSTGLP SLQEEPMLLA GSLRSAIDRC FKFNTVEEIL EALEKETEHK 300 301 EWAQKTLQTL SIRSPTSLRV ALRQMRVGKK WSISETFQRE HHIAAKFMQH PDFVEGVKAR 360 361 LMSKPARQAS WQPATLQEVT NADVDAFFQI PQGETRLPLL SETDYDNYPH AHYALPSEAE 420 421 IEKVVRGNTQ AQDKVVSEFV QKWGNKEGVR EKVAEVLARR TVRTPEGLQW VE 472

Protein Sequence (FASTA)

1     MPLRAKVTNP  AFGSTAKMST  SPDLPKELPG  DEPDDVLFNS  LYGVRLIELN  RPKKLNSLNG  60
61    SMARKILPRL  KEWEKSQLAN  VVMVSGAGSK  ALCAGGDVAA  LALQNEQGPE  GQQKSTDFFG  120
121   LEYCLDHTIA  TYPKPFISVM  DGITMGGGVG  LSVHAPFRIA  TERTVFAMPE  TTIGFFPDVG  180
181   GSFFLPRLDG  EVGTYLALTS  ERLTGVQTLY  AGIATHYLHS  SVLSNLTSRL  AELVFKDSAS  240
241   LPERLDLVNK  TMAEFSTGLP  SLQEEPMLLA  GSLRSAIDRC  FKFNTVEEIL  EALEKETEHK  300
301   EWAQKTLQTL  SIRSPTSLRV  ALRQMRVGKK  WSISETFQRE  HHIAAKFMQH  PDFVEGVKAR  360
361   LMSKPARQAS  WQPATLQEVT  NADVDAFFQI  PQGETRLPLL  SETDYDNYPH  AHYALPSEAE  420
421   IEKVVRGNTQ  AQDKVVSEFV  QKWGNKEGVR  EKVAEVLARR  TVRTPEGLQW  VE  472

▼ KEYWORD

ID	Family
KW-0101	Branched-chain amino acid catabolism
KW-0181	Complete proteome
KW-0378	Hydrolase
KW-0496	Mitochondrion
KW-1185	Reference proteome
KW-0809	Transit peptide

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005739	Cellular Component	Mitochondrion
GO:0003860	Molecular Function	3-hydroxyisobutyryl-CoA hydrolase activity
GO:0006574	Biological Process	Valine catabolic process

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Aso-0894	Aspergillus oryzae	87.23	0.0	832
LLPS-Asf-1574	Aspergillus flavus	86.9	0.0	764
LLPS-Asfu-1406	Aspergillus fumigatus	84.11	0.0	778
LLPS-Asc-1135	Aspergillus clavatus	83.4	0.0	805
LLPS-Nef-1525	Neosartorya fischeri	83.19	0.0	801
LLPS-Asn-1050	Aspergillus nidulans	75.21	0.0	720
LLPS-Asni-1073	Aspergillus niger	75.0	0.0	712
LLPS-Zyt-1021	Zymoseptoria tritici	66.67	1e-118	356
LLPS-Cogr-0909	Colletotrichum graminicola	59.24	0.0	545
LLPS-Trv-0743	Trichoderma virens	58.22	3e-178	516
LLPS-Cog-0938	Colletotrichum gloeosporioides	58.21	0.0	532
LLPS-Pyt-1639	Pyrenophora teres	58.21	0.0	530
LLPS-Ved-1589	Verticillium dahliae	58.02	0.0	525
LLPS-Pytr-0954	Pyrenophora triticirepentis	57.57	0.0	532
LLPS-Trr-0720	Trichoderma reesei	57.56	4e-176	510
LLPS-Coo-1542	Colletotrichum orbiculare	57.54	0.0	539
LLPS-Beb-1647	Beauveria bassiana	56.9	2e-177	514
LLPS-Lem-1245	Leptosphaeria maculans	56.08	1e-177	526
LLPS-Scs-0876	Sclerotinia sclerotiorum	56.06	0.0	545
LLPS-Fus-0994	Fusarium solani	56.03	3e-175	508
LLPS-Fuo-1575	Fusarium oxysporum	55.77	4e-178	516
LLPS-Tum-1391	Tuber melanosporum	55.53	7e-179	517
LLPS-Fuv-1514	Fusarium verticillioides	55.34	3e-176	511
LLPS-Dos-1489	Dothistroma septosporum	54.49	2e-177	514
LLPS-Phn-1482	Phaeosphaeria nodorum	54.16	6e-159	465
LLPS-Nec-1202	Neurospora crassa	54.13	1e-172	502
LLPS-Mao-1200	Magnaporthe oryzae	53.88	2e-168	491
LLPS-Gag-1303	Gaeumannomyces graminis	53.43	9e-171	497
LLPS-Blg-0922	Blumeria graminis	52.04	3e-169	496
LLPS-Abg-1463	Absidia glauca	45.65	8e-120	367
LLPS-Drm-1049	Drosophila melanogaster	45.43	7e-83	268
LLPS-Cas-2167	Carlito syrichta	44.14	4e-61	207
LLPS-Cii-2397	Ciona intestinalis	44.14	2e-88	282
LLPS-Xet-2957	Xenopus tropicalis	43.9	2e-82	266
LLPS-Cis-0744	Ciona savignyi	43.6	4e-89	284
LLPS-Lac-2939	Latimeria chalumnae	43.5	4e-83	268
LLPS-Leo-3624	Lepisosteus oculatus	43.38	2e-86	276
LLPS-Scf-2903	Scleropages formosus	43.29	6e-85	273
LLPS-Xim-2664	Xiphophorus maculatus	43.23	4e-68	229
LLPS-Dar-3829	Danio rerio	43.13	2e-81	264
LLPS-Fia-3838	Ficedula albicollis	43.09	2e-74	246
LLPS-Put-1348	Puccinia triticina	42.92	1e-91	308
LLPS-Pof-0448	Poecilia formosa	42.86	2e-80	261
LLPS-Orn-1447	Oreochromis niloticus	42.66	5e-85	273
LLPS-Orc-3621	Oryctolagus cuniculus	42.62	6e-73	242
LLPS-Ten-2922	Tetraodon nigroviridis	42.58	5e-78	255
LLPS-Gaga-2658	Gallus gallus	42.55	4e-82	265
LLPS-Tag-0074	Taeniopygia guttata	42.55	1e-72	240
LLPS-Meg-0328	Meleagris gallopavo	42.55	4e-82	266
LLPS-Sah-2128	Sarcophilus harrisii	42.44	7e-78	254
LLPS-Orl-2685	Oryzias latipes	42.39	1e-74	246
LLPS-Mum-3552	Mus musculus	42.36	9e-76	249
LLPS-Yal-0151	Yarrowia lipolytica	42.32	7e-120	366
LLPS-Urm-0656	Ursus maritimus	42.15	3e-78	255
LLPS-Dio-0082	Dipodomys ordii	42.15	4e-77	252
LLPS-Mea-2210	Mesocricetus auratus	42.11	7e-77	252
LLPS-Pes-1335	Pelodiscus sinensis	42.06	4e-78	255
LLPS-Asm-3282	Astyanax mexicanus	41.97	2e-78	256
LLPS-Gaa-3417	Gasterosteus aculeatus	41.93	6e-80	260
LLPS-Mup-1465	Mustela putorius furo	41.86	4e-77	253
LLPS-Pap-4569	Pan paniscus	41.8	2e-56	195
LLPS-Ran-4626	Rattus norvegicus	41.62	4e-78	255
LLPS-Mel-1309	Melampsora laricipopulina	41.61	1e-97	310
LLPS-Cae-1991	Caenorhabditis elegans	41.46	2e-76	251
LLPS-Mod-4328	Monodelphis domestica	41.23	3e-66	224
LLPS-Anc-1201	Anolis carolinensis	41.11	5e-71	237
LLPS-Fud-1423	Fukomys damarensis	40.96	3e-69	231
LLPS-Myl-2978	Myotis lucifugus	40.83	4e-71	237
LLPS-Anp-3164	Anas platyrhynchos	40.81	1e-76	251
LLPS-Loa-2743	Loxodonta africana	40.73	9e-75	246
LLPS-Mal-1900	Mandrillus leucophaeus	40.67	1e-74	246
LLPS-Cea-1129	Cercocebus atys	40.67	1e-74	246
LLPS-Ict-3568	Ictidomys tridecemlineatus	40.62	5e-78	255
LLPS-Ova-2588	Ovis aries	40.41	5e-64	218
LLPS-Sus-4180	Sus scrofa	40.39	1e-72	241
LLPS-Scm-0981	Scophthalmus maximus	40.34	9e-80	259
LLPS-Icp-1799	Ictalurus punctatus	40.32	3e-83	269
LLPS-Caj-4382	Callithrix jacchus	40.12	7e-72	239
LLPS-Poa-0150	Pongo abelii	40.11	1e-73	244
LLPS-Paa-4595	Papio anubis	40.11	3e-74	244
LLPS-Caf-1512	Canis familiaris	39.84	1e-74	246
LLPS-Nol-4001	Nomascus leucogenys	39.83	1e-73	243
LLPS-Pat-4296	Pan troglodytes	39.83	4e-73	242
LLPS-Hos-0953	Homo sapiens	39.83	4e-73	242
LLPS-Man-3550	Macaca nemestrina	39.83	6e-73	241
LLPS-Maf-3130	Macaca fascicularis	39.83	6e-73	241
LLPS-Cap-3013	Cavia porcellus	39.73	2e-64	219
LLPS-Bot-1862	Bos taurus	39.73	2e-63	216
LLPS-Fec-2804	Felis catus	39.62	4e-68	229
LLPS-Bro-0818	Brassica oleracea	39.55	2e-70	234
LLPS-Mam-1749	Macaca mulatta	39.55	4e-72	239
LLPS-Aon-0536	Aotus nancymaae	39.55	9e-73	241
LLPS-Brr-2685	Brassica rapa	39.51	1e-71	238
LLPS-Brn-1749	Brassica napus	39.51	1e-71	238
LLPS-Miv-0680	Microbotryum violaceum	39.42	2e-90	292
LLPS-Thc-0843	Theobroma cacao	39.39	8e-69	231
LLPS-Gog-0230	Gorilla gorilla	39.28	6e-73	242
LLPS-Prp-0021	Prunus persica	39.23	1e-68	230
LLPS-Chs-1006	Chlorocebus sabaeus	39.13	2e-65	221
LLPS-Scj-1055	Schizosaccharomyces japonicus	39.12	4e-73	243
LLPS-Tar-2589	Takifugu rubripes	39.12	4e-76	251
LLPS-Mae-0366	Manihot esculenta	39.11	7e-67	226
LLPS-Rhb-3883	Rhinopithecus bieti	38.84	1e-64	219
LLPS-Gas-0425	Galdieria sulphuraria	38.8	3e-71	238
LLPS-Pot-1001	Populus trichocarpa	38.74	4e-65	221
LLPS-Php-2169	Physcomitrella patens	38.71	1e-70	236
LLPS-Eqc-4263	Equus caballus	38.66	1e-64	219
LLPS-Mua-0263	Musa acuminata	38.63	4e-63	216
LLPS-Art-2956	Arabidopsis thaliana	38.55	1e-66	224
LLPS-Phv-2462	Phaseolus vulgaris	38.53	7e-64	218
LLPS-Sei-2004	Setaria italica	38.48	7e-64	219
LLPS-Nia-0166	Nicotiana attenuata	38.33	8e-67	226
LLPS-Sob-1926	Sorghum bicolor	38.3	9e-60	207
LLPS-Viv-0261	Vitis vinifera	38.27	1e-60	210
LLPS-Pug-1348	Puccinia graminis	38.25	6e-86	280
LLPS-Lep-0185	Leersia perrieri	38.17	1e-57	202
LLPS-Zem-1989	Zea mays	38.16	9e-60	207
LLPS-Met-1091	Medicago truncatula	38.08	4e-64	218
LLPS-Gor-2490	Gossypium raimondii	38.06	1e-66	225
LLPS-Aim-0188	Ailuropoda melanoleuca	38.02	3e-38	145
LLPS-Amt-1048	Amborella trichopoda	37.95	3e-62	213
LLPS-Dac-2346	Daucus carota	37.85	4e-63	215
LLPS-Brd-2197	Brachypodium distachyon	37.8	8e-61	210
LLPS-Otg-0273	Otolemur garnettii	37.79	4e-31	124
LLPS-Scp-1654	Schizosaccharomyces pombe	37.74	8e-81	263
LLPS-Arl-2879	Arabidopsis lyrata	37.7	8e-66	223
LLPS-Hov-0146	Hordeum vulgare	37.64	1e-62	215
LLPS-Tra-2061	Triticum aestivum	37.64	8e-61	209
LLPS-Cus-1070	Cucumis sativus	37.63	9e-66	223
LLPS-Ori-1383	Oryza indica	37.5	1e-58	205
LLPS-Hea-2382	Helianthus annuus	37.43	5e-69	231
LLPS-Ors-2367	Oryza sativa	37.32	2e-61	215
LLPS-Orni-1539	Oryza nivara	37.32	4e-61	215
LLPS-Coc-1911	Corchorus capsularis	37.22	6e-71	237
LLPS-Sol-1247	Solanum lycopersicum	37.22	1e-64	219
LLPS-Orp-0574	Oryza punctata	37.2	1e-56	199
LLPS-Scc-0311	Schizosaccharomyces cryophilus	37.15	4e-69	233
LLPS-Org-2126	Oryza glaberrima	37.04	1e-61	214
LLPS-Orb-1124	Oryza barthii	37.04	2e-62	214
LLPS-Orr-2140	Oryza rufipogon	36.94	2e-56	199
LLPS-Orgl-0494	Oryza glumaepatula	36.94	2e-56	199
LLPS-Glm-2563	Glycine max	36.93	3e-63	216
LLPS-Orbr-2270	Oryza brachyantha	36.76	2e-57	208
LLPS-Ora-3331	Ornithorhynchus anatinus	36.36	1e-16	80.9
LLPS-Tru-0333	Triticum urartu	36.14	4e-56	197
LLPS-Sot-1237	Solanum tuberosum	36.09	2e-59	206
LLPS-Via-1371	Vigna angularis	35.99	4e-57	205
LLPS-Vir-2074	Vigna radiata	35.69	4e-57	199
LLPS-Kop-0210	Komagataella pastoris	35.48	2e-75	252
LLPS-Sac-1282	Saccharomyces cerevisiae	34.83	9e-68	231
LLPS-Usm-0068	Ustilago maydis	33.89	8e-59	209
LLPS-Spr-0544	Sporisorium reilianum	33.66	2e-61	216
LLPS-Chc-0825	Chondrus crispus	33.33	4e-47	174
LLPS-Chr-1459	Chlamydomonas reinhardtii	32.69	7e-48	176
LLPS-Orm-1432	Oryza meridionalis	32.43	2e-41	157
LLPS-Cym-0712	Cyanidioschyzon merolae	31.92	2e-33	137
LLPS-Asg-1473	Ashbya gossypii	31.83	2e-57	203
LLPS-Osl-0876	Ostreococcus lucimarinus	30.32	1e-38	148
LLPS-Sem-1765	Selaginella moellendorffii	29.55	1e-44	166
LLPS-Crn-0044	Cryptococcus neoformans	29.49	3e-48	179

LLPS-Ast-1572ATEG_01986

Protein Sequence

Nucleotide Sequence

LLPS-Ast-1572
ATEG_01986