• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Brn-2980
BnaC08g15780D

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase
Gene Name: BnaC08g15780D, GSBRNA2T00096102001
Ensembl Gene: GSBRNA2T00096102001
Ensembl Protein: CDY50181
Organism: Brassica napus
Taxa ID: 3708
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCDY50181CDY50181
UniProtA0A078IJK8, A0A078IJK8_BRANA
GeneBankLK032886CDY50181.1
RefSeqXM_013801890.1XP_013657344.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MASTVFLSSF  SPSSSLQLRS  SFNGEYVSSS  RSFIGAAPFA  SSSLSLLSGQ  KNSYPQRKLH  60
61    VSAKKVSGLE  EAIRIRRMRE  LEKTSKVRRN  PPLRRGRVSP  RLLVPDHIPR  PPYVESGVLP  120
121   DISPEFQIPG  PEGIVKMRAA  CELAARVLNF  AGTLVKPSVT  TNEIDKAVHD  MIVEAGAYPS  180
181   PLGYGGFPKS  VCTSVNECMC  HGIPDSRQLQ  SGDIINIDVT  VYLDGYHGDT  SRTFFCGEVD  240
241   EGFKRLVKVT  EECLERGIAV  CKDGASFKKI  GKRISEHAEK  NGYNVVERFV  GHGVGPVFHS  300
301   EPLIYHYRND  GPGQMVEGQT  FTIEPILTIG  TTECVTWPDN  WTTLTADGGV  AAQCEHTILI  360
361   TRTGAEILTK  C  371
Nucleotide CDS Sequence (FASTA)
1     ATGGCGTCTA  CAGTCTTTCT  ATCCAGTTTC  TCGCCATCGT  CGTCGTTGCA  ACTCCGTTCT  60
61    TCTTTCAACG  GCGAGTACGT  ATCCTCCTCG  AGGAGCTTCA  TCGGAGCAGC  TCCGTTCGCT  120
121   TCCTCTTCTC  TATCGCTGCT  CTCCGGTCAG  AAGAACTCAT  ATCCTCAGAG  AAAACTCCAC  180
181   GTTTCCGCCA  AGAAAGTTTC  TGGATTAGAG  GAAGCCATTA  GAATCAGAAG  GATGAGAGAG  240
241   CTTGAGAAAA  CTTCAAAAGT  TAGGAGAAAC  CCACCGTTAC  GACGTGGAAG  AGTCTCCCCT  300
301   CGTCTCCTCG  TCCCTGATCA  CATACCAAGG  CCTCCTTACG  TTGAGTCTGG  CGTGTTACCT  360
361   GATATATCTC  CTGAGTTCCA  GATTCCTGGT  CCTGAAGGCA  TTGTGAAGAT  GAGAGCTGCT  420
421   TGCGAGCTCG  CTGCTCGTGT  TCTAAACTTT  GCAGGAACTT  TGGTTAAACC  ATCTGTGACG  480
481   ACTAATGAAA  TAGACAAAGC  GGTGCATGAC  ATGATTGTTG  AAGCTGGTGC  TTATCCTTCG  540
541   CCTCTTGGGT  ATGGTGGGTT  CCCTAAAAGT  GTGTGTACAT  CAGTTAACGA  GTGTATGTGT  600
601   CATGGGATAC  CGGATTCTCG  ACAGCTACAG  AGTGGGGATA  TAATAAACAT  CGATGTCACG  660
661   GTTTACTTGG  ATGGTTACCA  TGGAGATACA  TCTAGAACTT  TCTTCTGTGG  AGAAGTAGAT  720
721   GAAGGTTTTA  AACGACTTGT  AAAGGTTACG  GAGGAATGTT  TGGAGAGAGG  TATAGCCGTT  780
781   TGTAAAGATG  GAGCAAGCTT  CAAGAAAATC  GGCAAGCGAA  TAAGCGAGCA  TGCTGAAAAG  840
841   AACGGCTACA  ACGTGGTGGA  GCGCTTTGTT  GGGCATGGTG  TAGGACCAGT  GTTCCACTCA  900
901   GAACCCTTGA  TTTATCATTA  CCGAAATGAT  GGGCCTGGGC  AAATGGTTGA  AGGACAAACT  960
961   TTCACAATTG  AACCGATTCT  GACGATTGGA  ACCACGGAAT  GTGTAACATG  GCCAGACAAC  1020
1021  TGGACTACTC  TGACAGCTGA  TGGTGGGGTA  GCCGCACAGT  GTGAGCATAC  AATTCTGATT  1080
1081  ACTAGAACTG  GTGCTGAGAT  TCTTACCAAG  TGCTGA  1116

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bro-1586Brassica oleracea99.710.0 706
LLPS-Art-2350Arabidopsis thaliana91.120.0 643
LLPS-Brr-1993Brassica rapa90.830.0 644
LLPS-Arl-1257Arabidopsis lyrata89.40.0 639
LLPS-Pot-0077Populus trichocarpa80.690.0 532
LLPS-Thc-0673Theobroma cacao79.110.0 527
LLPS-Dac-1225Daucus carota78.833e-141 422
LLPS-Mae-2055Manihot esculenta78.820.0 528
LLPS-Prp-1642Prunus persica78.570.0 526
LLPS-Coc-2232Corchorus capsularis78.190.0 528
LLPS-Mua-0049Musa acuminata77.531e-177 508
LLPS-Hea-2606Helianthus annuus76.880.0 514
LLPS-Gor-2693Gossypium raimondii75.520.0 523
LLPS-Viv-2015Vitis vinifera75.447e-176 501
LLPS-Amt-1369Amborella trichopoda75.01e-176 503
LLPS-Nia-1730Nicotiana attenuata74.860.0 520
LLPS-Sot-0149Solanum tuberosum73.074e-174 496
LLPS-Met-0176Medicago truncatula72.834e-180 511
LLPS-Via-2107Vigna angularis71.354e-179 509
LLPS-Hov-1721Hordeum vulgare70.936e-156 453
LLPS-Sob-1365Sorghum bicolor69.258e-159 457
LLPS-Tra-1836Triticum aestivum69.114e-159 458
LLPS-Brd-1091Brachypodium distachyon68.837e-159 457
LLPS-Orm-1323Oryza meridionalis68.775e-155 450
LLPS-Orp-2247Oryza punctata68.523e-159 458
LLPS-Orgl-0607Oryza glumaepatula68.452e-154 446
LLPS-Orb-0206Oryza barthii68.352e-155 448
LLPS-Org-2129Oryza glaberrima68.353e-155 447
LLPS-Zem-2266Zea mays68.091e-139 407
LLPS-Sei-0151Setaria italica67.872e-136 398
LLPS-Orbr-2256Oryza brachyantha67.85e-155 447
LLPS-Orni-2050Oryza nivara67.724e-154 445
LLPS-Ori-0671Oryza indica67.724e-154 445
LLPS-Ors-1643Oryza sativa67.724e-154 445
LLPS-Orr-2361Oryza rufipogon67.724e-154 445
LLPS-Php-2283Physcomitrella patens64.015e-139 408
LLPS-Lep-2070Leersia perrieri61.07e-151 438
LLPS-Glm-0512Glycine max60.322e-131 387
LLPS-Sem-1318Selaginella moellendorffii59.326e-130 383
LLPS-Sol-2256Solanum lycopersicum58.866e-125 371
LLPS-Xet-3203Xenopus tropicalis54.181e-94 293
LLPS-Tru-1051Triticum urartu54.083e-73 243
LLPS-Caj-1831Callithrix jacchus53.932e-93 290
LLPS-Aon-2499Aotus nancymaae53.935e-93 289
LLPS-Ova-3568Ovis aries53.932e-94 292
LLPS-Poa-4306Pongo abelii53.939e-94 290
LLPS-Gog-4670Gorilla gorilla53.569e-94 290
LLPS-Ora-1953Ornithorhynchus anatinus53.564e-93 288
LLPS-Chs-0513Chlorocebus sabaeus53.564e-93 289
LLPS-Cea-2140Cercocebus atys53.562e-92 288
LLPS-Sah-3500Sarcophilus harrisii53.568e-93 288
LLPS-Mal-2251Mandrillus leucophaeus53.563e-93 290
LLPS-Aim-3648Ailuropoda melanoleuca53.562e-93 290
LLPS-Mup-3127Mustela putorius furo53.564e-94 291
LLPS-Tut-2292Tursiops truncatus53.566e-93 292
LLPS-Rhb-4779Rhinopithecus bieti53.568e-94 291
LLPS-Pap-2349Pan paniscus53.568e-94 291
LLPS-Urm-3015Ursus maritimus53.565e-93 289
LLPS-Pat-3954Pan troglodytes53.568e-94 291
LLPS-Hos-1545Homo sapiens53.568e-94 291
LLPS-Nol-2922Nomascus leucogenys53.561e-92 287
LLPS-Meg-1246Meleagris gallopavo53.547e-77 245
LLPS-Maf-0633Macaca fascicularis53.482e-94 292
LLPS-Fec-2040Felis catus53.481e-92 291
LLPS-Man-4478Macaca nemestrina53.482e-94 292
LLPS-Ict-0147Ictidomys tridecemlineatus53.485e-94 291
LLPS-Mam-1602Macaca mulatta53.482e-94 292
LLPS-Bot-3175Bos taurus53.418e-92 286
LLPS-Sus-0419Sus scrofa53.283e-84 267
LLPS-Fud-3767Fukomys damarensis53.188e-92 286
LLPS-Myl-1610Myotis lucifugus53.184e-93 289
LLPS-Caf-4304Canis familiaris53.182e-91 288
LLPS-Mod-3236Monodelphis domestica53.116e-93 289
LLPS-Ran-4151Rattus norvegicus52.757e-91 283
LLPS-Fia-3369Ficedula albicollis52.554e-91 284
LLPS-Gaga-2447Gallus gallus52.381e-92 289
LLPS-Tag-1775Taeniopygia guttata52.386e-93 288
LLPS-Anp-3124Anas platyrhynchos52.271e-89 280
LLPS-Asm-2277Astyanax mexicanus52.167e-91 284
LLPS-Orl-2389Oryzias latipes52.163e-91 285
LLPS-Orc-0335Oryctolagus cuniculus52.061e-91 285
LLPS-Pof-0831Poecilia formosa51.87e-92 286
LLPS-Icp-3843Ictalurus punctatus51.447e-88 276
LLPS-Gaa-1895Gasterosteus aculeatus51.448e-91 283
LLPS-Scf-3038Scleropages formosus51.447e-90 280
LLPS-Xim-3616Xiphophorus maculatus51.084e-90 282
LLPS-Orn-0115Oreochromis niloticus51.082e-88 277
LLPS-Scm-0334Scophthalmus maximus51.083e-90 281
LLPS-Ten-0306Tetraodon nigroviridis51.084e-90 280
LLPS-Loa-3307Loxodonta africana50.94e-86 271
LLPS-Cym-0199Cyanidioschyzon merolae50.78e-89 281
LLPS-Otg-2188Otolemur garnettii50.673e-95 294
LLPS-Cap-1504Cavia porcellus50.672e-95 295
LLPS-Lac-1881Latimeria chalumnae50.555e-90 281
LLPS-Dar-3283Danio rerio50.362e-87 274
LLPS-Cus-0278Cucumis sativus50.352e-90 284
LLPS-Paa-2148Papio anubis50.02e-93 290
LLPS-Eqc-4675Equus caballus50.02e-73 243
LLPS-Cas-3474Carlito syrichta49.678e-93 288
LLPS-Drm-1381Drosophila melanogaster49.643e-85 268
LLPS-Cii-0531Ciona intestinalis49.466e-82 258
LLPS-Chr-0269Chlamydomonas reinhardtii48.771e-91 287
LLPS-Cae-0853Caenorhabditis elegans48.624e-85 270
LLPS-Phv-1362Phaseolus vulgaris48.592e-90 284
LLPS-Mel-0446Melampsora laricipopulina48.583e-81 261
LLPS-Mum-3444Mus musculus48.553e-91 284
LLPS-Leo-0587Lepisosteus oculatus48.479e-88 278
LLPS-Phn-0046Phaeosphaeria nodorum48.12e-71 233
LLPS-Anc-1102Anolis carolinensis47.88e-86 272
LLPS-Tar-1922Takifugu rubripes47.04e-89 279
LLPS-Kop-0430Komagataella pastoris46.817e-79 253
LLPS-Dio-1198Dipodomys ordii46.444e-84 268
LLPS-Pes-0257Pelodiscus sinensis46.442e-84 267
LLPS-Mao-1044Magnaporthe oryzae46.262e-79 256
LLPS-Abg-0864Absidia glauca46.248e-82 260
LLPS-Nec-0021Neurospora crassa46.15e-80 256
LLPS-Pug-0119Puccinia graminis46.072e-77 251
LLPS-Osl-0679Ostreococcus lucimarinus45.991e-69 226
LLPS-Zyt-0262Zymoseptoria tritici45.711e-75 246
LLPS-Scc-0849Schizosaccharomyces cryophilus45.689e-74 240
LLPS-Gag-0143Gaeumannomyces graminis45.551e-78 254
LLPS-Blg-0668Blumeria graminis45.391e-72 237
LLPS-Ast-0847Aspergillus terreus45.042e-75 245
LLPS-Yal-0719Yarrowia lipolytica45.02e-75 244
LLPS-Scj-0173Schizosaccharomyces japonicus44.722e-74 242
LLPS-Map-0033Magnaporthe poae44.681e-77 251
LLPS-Lem-0193Leptosphaeria maculans44.685e-74 243
LLPS-Dos-1172Dothistroma septosporum44.681e-74 243
LLPS-Asni-0419Aspergillus niger44.486e-73 238
LLPS-Gas-0287Galdieria sulphuraria44.413e-84 268
LLPS-Usm-0427Ustilago maydis44.46e-71 233
LLPS-Asf-0343Aspergillus flavus44.333e-74 242
LLPS-Aso-0501Aspergillus oryzae44.333e-74 242
LLPS-Nef-0238Neosartorya fischeri44.336e-74 241
LLPS-Ved-0455Verticillium dahliae44.332e-75 246
LLPS-Miv-0608Microbotryum violaceum44.132e-71 235
LLPS-Cogr-0748Colletotrichum graminicola44.068e-75 244
LLPS-Asn-0947Aspergillus nidulans43.976e-73 239
LLPS-Asc-1200Aspergillus clavatus43.973e-75 245
LLPS-Chc-0445Chondrus crispus43.972e-76 247
LLPS-Beb-0556Beauveria bassiana43.887e-70 231
LLPS-Scp-0382Schizosaccharomyces pombe43.751e-70 233
LLPS-Fuv-0523Fusarium verticillioides43.625e-74 241
LLPS-Fus-0244Fusarium solani43.623e-73 239
LLPS-Fuo-0195Fusarium oxysporum43.628e-74 241
LLPS-Coo-0004Colletotrichum orbiculare43.367e-75 244
LLPS-Pyt-0572Pyrenophora teres43.264e-73 239
LLPS-Pytr-0418Pyrenophora triticirepentis43.269e-73 238
LLPS-Scs-0874Sclerotinia sclerotiorum43.212e-70 233
LLPS-Trr-0555Trichoderma reesei42.913e-69 229
LLPS-Put-0226Puccinia triticina42.816e-73 240
LLPS-Cog-0084Colletotrichum gloeosporioides42.667e-72 236
LLPS-Sac-0088Saccharomyces cerevisiae42.512e-80 258
LLPS-Crn-0028Cryptococcus neoformans42.463e-78 253
LLPS-Asfu-1037Aspergillus fumigatus41.916e-70 232
LLPS-Asg-0921Ashbya gossypii41.672e-75 244