• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pytr-0418
PTRG_07298

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase
Gene Name: PTRG_07298
Ensembl Gene: PTRG_07298
Ensembl Protein: EDU50217
Organism: Pyrenophora triticirepentis
Taxa ID: 426418
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEDU50217EDU50217
UniProtB2WAI5, B2WAI5_PYRTR
GeneBankDS231621EDU50217.1
RefSeqXM_001937595.1XP_001937630.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAVDAPRKCS  GKDCDNDAGT  LQCPNCQKLG  KESFFCSQDC  FKRNWGEHKK  EHKSQSSILQ  60
61    SIFTPKVVSY  PDPATGHYNP  FPTYPYTGAL  RPVYPLSPRR  EVPKHIRLPD  YAKDGIPRSE  120
121   QVFVNRNKIT  ILSKEEQDAM  RKVCRYGREI  LDIAGRAAKP  GVTTDYIDEI  VHNATIERDS  180
181   YPSPLNYCNF  PKSVCTSLNE  VICHGIPDQR  VLKDGDILNI  DISVYHGGFH  ADLNETYYIG  240
241   DKALANPDAV  RVTEAARECL  DKAIEIVKPG  TLFREYGNVI  EKHAKTKNCS  VIRTYCGHGV  300
301   NQLFHCAPNV  PHYAKNKAIG  QAKPGMCFTI  EPMISLGSHR  DKTWPDDWTS  VTQDGSLTAQ  360
361   FEHTLLVTED  GVEVLTARLP  DSPGGPVQIP  GVTDGEKKEE  VTAAS  405
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGTAG  ACGCCCCGCG  CAAATGCTCG  GGCAAGGATT  GCGACAACGA  CGCCGGCACG  60
61    TTGCAGTGCC  CAAACTGCCA  GAAACTTGGC  AAAGAAAGCT  TCTTTTGCTC  ACAGGACTGC  120
121   TTCAAGCGAA  ACTGGGGTGA  ACACAAGAAG  GAGCACAAGT  CACAAAGTAG  TATTCTCCAA  180
181   AGTATCTTTA  CGCCGAAAGT  AGTTTCTTAC  CCGGATCCAG  CCACCGGTCA  TTACAACCCG  240
241   TTCCCCACGT  ATCCGTACAC  TGGAGCCCTA  AGACCTGTAT  ACCCGCTGTC  GCCGCGACGC  300
301   GAAGTGCCGA  AGCACATCAG  GCTACCCGAT  TACGCAAAGG  ATGGCATACC  GCGTTCAGAG  360
361   CAGGTGTTTG  TCAATAGGAA  TAAGATTACG  ATTTTGAGCA  AGGAGGAGCA  GGATGCGATG  420
421   CGCAAAGTGT  GTCGATATGG  ACGGGAGATT  CTCGACATTG  CAGGGCGAGC  TGCAAAGCCT  480
481   GGCGTCACGA  CCGATTACAT  CGATGAAATT  GTCCATAATG  CCACCATCGA  GCGTGATTCG  540
541   TATCCATCGC  CCCTCAACTA  CTGCAACTTT  CCCAAATCAG  TTTGCACGTC  GCTCAACGAG  600
601   GTCATCTGCC  ACGGCATCCC  CGATCAGCGA  GTACTCAAAG  ACGGCGACAT  TCTAAACATC  660
661   GACATCTCGG  TATACCATGG  CGGTTTCCAC  GCGGATCTGA  ACGAGACATA  TTACATTGGT  720
721   GACAAGGCAT  TGGCGAATCC  CGACGCGGTG  CGGGTGACTG  AGGCAGCGCG  GGAATGCTTA  780
781   GACAAGGCCA  TCGAAATCGT  CAAGCCCGGC  ACACTCTTCC  GCGAGTACGG  AAACGTCATC  840
841   GAGAAGCACG  CAAAGACCAA  GAACTGCAGC  GTAATCAGGA  CGTATTGCGG  ACACGGTGTG  900
901   AACCAATTGT  TTCACTGCGC  ACCCAACGTA  CCGCATTACG  CAAAGAACAA  GGCGATCGGC  960
961   CAGGCGAAAC  CAGGCATGTG  CTTCACAATC  GAGCCCATGA  TCAGTCTCGG  TTCACACAGG  1020
1021  GACAAGACAT  GGCCGGATGA  TTGGACTAGC  GTCACACAGG  ACGGCTCTCT  GACAGCGCAG  1080
1081  TTCGAACATA  CCCTACTCGT  AACCGAGGAT  GGTGTCGAGG  TCCTGACGGC  AAGACTGCCA  1140
1141  GATTCACCAG  GTGGCCCCGT  ACAAATACCG  GGAGTCACAG  ACGGTGAGAA  GAAGGAAGAA  1200
1201  GTGACGGCCG  CGTCTTGA  1218

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Pyt-0572Pyrenophora teres98.270.0 836
LLPS-Phn-0046Phaeosphaeria nodorum87.460.0 542
LLPS-Lem-0193Leptosphaeria maculans82.970.0 728
LLPS-Scs-0874Sclerotinia sclerotiorum76.690.0 660
LLPS-Ast-0847Aspergillus terreus75.70.0 647
LLPS-Asn-0947Aspergillus nidulans74.680.0 634
LLPS-Asf-0343Aspergillus flavus74.380.0 650
LLPS-Aso-0501Aspergillus oryzae74.380.0 650
LLPS-Nef-0238Neosartorya fischeri74.00.0 649
LLPS-Tum-0972Tuber melanosporum73.385e-145 420
LLPS-Ved-0455Verticillium dahliae73.010.0 609
LLPS-Asc-1200Aspergillus clavatus72.910.0 634
LLPS-Fus-0244Fusarium solani72.770.0 605
LLPS-Asni-0419Aspergillus niger72.310.0 600
LLPS-Dos-1172Dothistroma septosporum72.310.0 615
LLPS-Zyt-0262Zymoseptoria tritici72.060.0 629
LLPS-Coo-0004Colletotrichum orbiculare71.830.0 594
LLPS-Cogr-0748Colletotrichum graminicola70.740.0 591
LLPS-Cog-0084Colletotrichum gloeosporioides70.360.0 584
LLPS-Asfu-1037Aspergillus fumigatus70.310.0 638
LLPS-Mao-1044Magnaporthe oryzae69.610.0 578
LLPS-Trv-1363Trichoderma virens69.350.0 578
LLPS-Trr-0555Trichoderma reesei69.330.0 580
LLPS-Fuo-0195Fusarium oxysporum68.830.0 576
LLPS-Fuv-0523Fusarium verticillioides68.580.0 576
LLPS-Map-0033Magnaporthe poae68.310.0 561
LLPS-Beb-0556Beauveria bassiana67.430.0 544
LLPS-Gag-0143Gaeumannomyces graminis67.180.0 556
LLPS-Blg-0668Blumeria graminis66.750.0 570
LLPS-Nec-0021Neurospora crassa65.630.0 528
LLPS-Scc-0849Schizosaccharomyces cryophilus62.661e-172 495
LLPS-Amt-0117Amborella trichopoda62.032e-79 251
LLPS-Yal-0719Yarrowia lipolytica61.848e-170 488
LLPS-Scp-0382Schizosaccharomyces pombe61.12e-170 489
LLPS-Scj-0173Schizosaccharomyces japonicus60.892e-167 482
LLPS-Meg-0314Meleagris gallopavo58.879e-111 333
LLPS-Abg-0864Absidia glauca58.549e-149 433
LLPS-Urm-1478Ursus maritimus57.433e-122 366
LLPS-Kop-0430Komagataella pastoris56.022e-156 453
LLPS-Chc-0445Chondrus crispus55.643e-140 412
LLPS-Tru-0409Triticum urartu55.441e-110 335
LLPS-Orl-3326Oryzias latipes55.242e-143 421
LLPS-Xim-2979Xiphophorus maculatus55.217e-143 419
LLPS-Mua-1647Musa acuminata55.163e-135 400
LLPS-Scm-2983Scophthalmus maximus55.148e-131 388
LLPS-Tar-0970Takifugu rubripes55.062e-100 307
LLPS-Sac-0088Saccharomyces cerevisiae54.869e-151 439
LLPS-Leo-0587Lepisosteus oculatus54.812e-142 419
LLPS-Asg-0921Ashbya gossypii54.646e-144 421
LLPS-Fia-0872Ficedula albicollis54.64e-132 390
LLPS-Chr-0269Chlamydomonas reinhardtii54.372e-132 393
LLPS-Tag-2049Taeniopygia guttata54.333e-142 417
LLPS-Dar-1374Danio rerio54.298e-143 420
LLPS-Gaa-1542Gasterosteus aculeatus54.178e-139 409
LLPS-Sob-0072Sorghum bicolor53.952e-133 395
LLPS-Gaga-0776Gallus gallus53.932e-140 413
LLPS-Pes-0257Pelodiscus sinensis53.781e-128 382
LLPS-Orc-0077Oryctolagus cuniculus53.761e-132 392
LLPS-Orn-2085Oreochromis niloticus53.652e-140 414
LLPS-Mal-1006Mandrillus leucophaeus53.641e-125 374
LLPS-Ova-0293Ovis aries53.642e-126 376
LLPS-Sah-0473Sarcophilus harrisii53.641e-126 376
LLPS-Pof-0946Poecilia formosa53.634e-138 407
LLPS-Drm-0528Drosophila melanogaster53.483e-133 394
LLPS-Thc-0611Theobroma cacao53.461e-130 389
LLPS-Anc-1102Anolis carolinensis53.43e-140 412
LLPS-Icp-0907Ictalurus punctatus53.395e-140 412
LLPS-Tut-0231Tursiops truncatus53.351e-125 374
LLPS-Fud-1166Fukomys damarensis53.353e-125 374
LLPS-Gog-0921Gorilla gorilla53.352e-125 374
LLPS-Pap-0898Pan paniscus53.352e-125 374
LLPS-Mod-1231Monodelphis domestica53.312e-127 379
LLPS-Myl-1774Myotis lucifugus53.169e-129 382
LLPS-Paa-0237Papio anubis53.145e-138 407
LLPS-Aim-1190Ailuropoda melanoleuca53.144e-138 407
LLPS-Dio-1198Dipodomys ordii53.147e-138 407
LLPS-Caj-2157Callithrix jacchus53.149e-138 406
LLPS-Sus-0156Sus scrofa53.144e-138 407
LLPS-Cea-0429Cercocebus atys53.146e-138 407
LLPS-Maf-0291Macaca fascicularis53.145e-138 407
LLPS-Chs-0063Chlorocebus sabaeus53.145e-138 407
LLPS-Ict-1599Ictidomys tridecemlineatus53.144e-138 407
LLPS-Mam-1056Macaca mulatta53.145e-138 407
LLPS-Eqc-0237Equus caballus53.141e-135 406
LLPS-Rhb-0262Rhinopithecus bieti53.145e-138 407
LLPS-Man-1586Macaca nemestrina53.145e-138 407
LLPS-Fec-0622Felis catus53.145e-138 407
LLPS-Sei-0819Setaria italica53.131e-130 388
LLPS-Zem-0045Zea mays53.135e-132 392
LLPS-Coc-0151Corchorus capsularis53.11e-129 390
LLPS-Osl-0679Ostreococcus lucimarinus53.022e-101 309
LLPS-Scf-1846Scleropages formosus52.996e-137 406
LLPS-Ors-0426Oryza sativa52.976e-132 392
LLPS-Pot-1474Populus trichocarpa52.967e-129 384
LLPS-Aon-2134Aotus nancymaae52.881e-137 406
LLPS-Nol-0554Nomascus leucogenys52.889e-138 406
LLPS-Poa-1572Pongo abelii52.882e-137 405
LLPS-Loa-2096Loxodonta africana52.889e-138 406
LLPS-Pat-2120Pan troglodytes52.882e-137 405
LLPS-Asm-0090Astyanax mexicanus52.812e-140 413
LLPS-Caf-1322Canis familiaris52.791e-127 380
LLPS-Mum-3460Mus musculus52.732e-137 405
LLPS-Ten-1674Tetraodon nigroviridis52.732e-139 410
LLPS-Sol-1004Solanum lycopersicum52.669e-130 399
LLPS-Ran-0546Rattus norvegicus52.625e-137 404
LLPS-Hos-1310Homo sapiens52.624e-137 405
LLPS-Brn-0414Brassica napus52.485e-129 385
LLPS-Brr-0510Brassica rapa52.488e-129 384
LLPS-Otg-1342Otolemur garnettii52.476e-138 407
LLPS-Tra-2976Triticum aestivum52.451e-133 396
LLPS-Orbr-0931Oryza brachyantha52.36e-132 392
LLPS-Hea-0160Helianthus annuus52.211e-130 389
LLPS-Sot-1223Solanum tuberosum52.132e-133 396
LLPS-Mel-0446Melampsora laricipopulina52.094e-133 395
LLPS-Sem-1451Selaginella moellendorffii52.013e-134 398
LLPS-Mup-3273Mustela putorius furo51.992e-103 316
LLPS-Mae-0615Manihot esculenta51.863e-130 388
LLPS-Hov-0818Hordeum vulgare51.766e-129 385
LLPS-Bot-0190Bos taurus51.636e-114 345
LLPS-Via-1103Vigna angularis51.542e-121 367
LLPS-Art-0785Arabidopsis thaliana51.482e-127 380
LLPS-Gor-0761Gossypium raimondii51.41e-133 396
LLPS-Crn-0028Cryptococcus neoformans51.355e-126 377
LLPS-Xet-0450Xenopus tropicalis51.35e-132 392
LLPS-Glm-1333Glycine max51.217e-127 379
LLPS-Dac-0078Daucus carota51.182e-116 350
LLPS-Php-2266Physcomitrella patens51.051e-130 389
LLPS-Arl-0179Arabidopsis lyrata50.944e-127 380
LLPS-Miv-0608Microbotryum violaceum50.834e-115 349
LLPS-Cus-0278Cucumis sativus50.86e-129 384
LLPS-Gas-0287Galdieria sulphuraria50.783e-131 389
LLPS-Prp-0695Prunus persica50.653e-132 393
LLPS-Brd-1685Brachypodium distachyon50.523e-132 392
LLPS-Phv-1362Phaseolus vulgaris50.273e-127 380
LLPS-Anp-2549Anas platyrhynchos50.02e-109 332
LLPS-Cym-0199Cyanidioschyzon merolae49.744e-118 358
LLPS-Usm-0427Ustilago maydis49.694e-107 328
LLPS-Cae-0853Caenorhabditis elegans49.483e-123 369
LLPS-Cap-2557Cavia porcellus49.482e-121 364
LLPS-Pug-0119Puccinia graminis49.372e-125 376
LLPS-Lep-0747Leersia perrieri49.195e-115 350
LLPS-Orp-0393Oryza punctata48.387e-111 340
LLPS-Spr-0292Sporisorium reilianum48.287e-104 320
LLPS-Put-0226Puccinia triticina46.178e-121 365
LLPS-Viv-2457Vitis vinifera46.053e-79 255
LLPS-Ori-1186Oryza indica45.149e-96 297
LLPS-Bro-0841Brassica oleracea44.912e-97 303
LLPS-Met-0176Medicago truncatula44.682e-73 240
LLPS-Orgl-0607Oryza glumaepatula44.684e-73 238
LLPS-Orb-0206Oryza barthii44.687e-73 238
LLPS-Org-2129Oryza glaberrima44.685e-73 238
LLPS-Orni-2050Oryza nivara44.527e-73 238
LLPS-Orr-2361Oryza rufipogon44.527e-73 238
LLPS-Orm-1323Oryza meridionalis44.333e-72 238
LLPS-Nia-1730Nicotiana attenuata43.425e-73 239
LLPS-Vir-0276Vigna radiata42.244e-98 305
LLPS-Lac-1881Latimeria chalumnae41.892e-72 236
LLPS-Cii-0531Ciona intestinalis40.972e-68 224
LLPS-Ora-1953Ornithorhynchus anatinus40.071e-70 231
LLPS-Cas-3474Carlito syrichta40.02e-66 221