DrLLPS - Data resource of LLPS

LLPS-Asc-1200
ACLA_081470

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Methionine aminopeptidase
Gene Name:	ACLA_081470
Ensembl Gene:	ACLA_081470
Ensembl Protein:	EAW06459
Organism:	Aspergillus clavatus
Taxa ID:	344612
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Bos taurus	LLPS-Bot-0190	A6QLA4	Client	Nucleolus	55.52	4e-125	374
Homo sapiens	LLPS-Hos-1310	P53582	Client	Nucleolus	56.05	2e-147	431
Saccharomyces cerevisiae	LLPS-Sac-0088	Q01662	Client	Stress granule, Others	52.91	1e-148	434
Arabidopsis thaliana	LLPS-Art-0785	Q9SLN5	Client	Nucleolus	53.71	1e-140	414

▼ FUNCTION

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	EAW06459	EAW06459
UniProt		A1CT22, A1CT22_ASPCL
GeneBank	DS027060	EAW06459.1
RefSeq	XM_001267884.1	XP_001267885.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MAAEVAARKC MGVDCENNAG TLQCPTCLKM GTDSFFCSQD CFKRSWSEHK TIHKKSNILS 60 61 NLFPPKVVSE PDPATGHFNP FPSFQFTGPL RPVYPLSPMR TIPKSIPHPD YAKDGIPRSE 120 121 QKFVGRHNIT ILNKEEQEGM RKVCRLAREV LDIAAREVRP GVTTDHIDEV VHKACIERNS 180 181 YPSPLNYMHF PKSVCTSINE TICHGIPDQR PLEDGDIVNI DVTLYHNGFH GDLNETYYVG 240 241 DKARANPDAV RVVETSRECL EKSIALVKPG MLFREPGNVI DNYAKSRGCS TVKSYCGHGI 300 301 NQLFHCAPNV PHYAKNKAVG TAKPGMCFTI EPMINLGTHR DRTWPDDWTS TTADGALSAQ 360 361 FEHTLLVTED GVEVLTARLP DSPGGPIPMP VAEEAKPSEN 400

Protein Sequence (FASTA)

1     MAAEVAARKC  MGVDCENNAG  TLQCPTCLKM  GTDSFFCSQD  CFKRSWSEHK  TIHKKSNILS  60
61    NLFPPKVVSE  PDPATGHFNP  FPSFQFTGPL  RPVYPLSPMR  TIPKSIPHPD  YAKDGIPRSE  120
121   QKFVGRHNIT  ILNKEEQEGM  RKVCRLAREV  LDIAAREVRP  GVTTDHIDEV  VHKACIERNS  180
181   YPSPLNYMHF  PKSVCTSINE  TICHGIPDQR  PLEDGDIVNI  DVTLYHNGFH  GDLNETYYVG  240
241   DKARANPDAV  RVVETSRECL  EKSIALVKPG  MLFREPGNVI  DNYAKSRGCS  TVKSYCGHGI  300
301   NQLFHCAPNV  PHYAKNKAVG  TAKPGMCFTI  EPMINLGTHR  DRTWPDDWTS  TTADGALSAQ  360
361   FEHTLLVTED  GVEVLTARLP  DSPGGPIPMP  VAEEAKPSEN  400

▼ KEYWORD

ID	Family
KW-0031	Aminopeptidase
KW-0181	Complete proteome
KW-0378	Hydrolase
KW-0479	Metal-binding
KW-0645	Protease
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0046872	Molecular Function	Metal ion binding
GO:0070006	Molecular Function	Metalloaminopeptidase activity
GO:0070084	Biological Process	Protein initiator methionine removal

▼ KEGG

act:ACLA_081470

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Nef-0238	Neosartorya fischeri	93.27	0.0	791
LLPS-Ast-0847	Aspergillus terreus	91.44	0.0	775
LLPS-Aso-0501	Aspergillus oryzae	89.5	0.0	759
LLPS-Asf-0343	Aspergillus flavus	89.5	0.0	759
LLPS-Asn-0947	Aspergillus nidulans	89.37	0.0	756
LLPS-Asfu-1037	Aspergillus fumigatus	88.39	0.0	780
LLPS-Asni-0419	Aspergillus niger	84.02	0.0	689
LLPS-Phn-0046	Phaeosphaeria nodorum	80.78	1e-175	501
LLPS-Tum-0972	Tuber melanosporum	80.08	3e-153	441
LLPS-Scs-0874	Sclerotinia sclerotiorum	74.69	0.0	645
LLPS-Lem-0193	Leptosphaeria maculans	74.32	0.0	643
LLPS-Pyt-0572	Pyrenophora teres	73.25	0.0	638
LLPS-Zyt-0262	Zymoseptoria tritici	72.92	0.0	602
LLPS-Pytr-0418	Pyrenophora triticirepentis	72.91	0.0	634
LLPS-Mao-1044	Magnaporthe oryzae	72.09	0.0	602
LLPS-Coo-0004	Colletotrichum orbiculare	71.14	0.0	599
LLPS-Ved-0455	Verticillium dahliae	70.8	0.0	592
LLPS-Dos-1172	Dothistroma septosporum	70.76	0.0	594
LLPS-Cogr-0748	Colletotrichum graminicola	70.41	0.0	591
LLPS-Cog-0084	Colletotrichum gloeosporioides	69.54	0.0	590
LLPS-Fus-0244	Fusarium solani	69.35	0.0	592
LLPS-Map-0033	Magnaporthe poae	68.48	0.0	578
LLPS-Blg-0668	Blumeria graminis	68.23	0.0	563
LLPS-Gag-0143	Gaeumannomyces graminis	68.19	0.0	576
LLPS-Trv-1363	Trichoderma virens	67.94	0.0	568
LLPS-Trr-0555	Trichoderma reesei	67.43	0.0	572
LLPS-Beb-0556	Beauveria bassiana	67.34	0.0	547
LLPS-Nec-0021	Neurospora crassa	67.01	0.0	552
LLPS-Amt-0117	Amborella trichopoda	66.84	6e-85	265
LLPS-Fuo-0195	Fusarium oxysporum	65.82	0.0	558
LLPS-Fuv-0523	Fusarium verticillioides	65.33	0.0	558
LLPS-Meg-0314	Meleagris gallopavo	63.4	2e-118	353
LLPS-Scp-0382	Schizosaccharomyces pombe	63.33	1e-179	513
LLPS-Scc-0849	Schizosaccharomyces cryophilus	62.56	2e-177	507
LLPS-Scj-0173	Schizosaccharomyces japonicus	61.64	9e-177	506
LLPS-Urm-1478	Ursus maritimus	60.73	6e-130	385
LLPS-Tru-0409	Triticum urartu	59.66	4e-119	357
LLPS-Yal-0719	Yarrowia lipolytica	59.63	2e-171	491
LLPS-Abg-0864	Absidia glauca	59.52	4e-156	452
LLPS-Kop-0430	Komagataella pastoris	59.21	2e-165	476
LLPS-Scm-2983	Scophthalmus maximus	58.45	4e-142	416
LLPS-Tar-0970	Takifugu rubripes	58.43	9e-105	318
LLPS-Fia-0872	Ficedula albicollis	58.21	4e-141	414
LLPS-Sei-0819	Setaria italica	58.2	1e-145	427
LLPS-Dar-1374	Danio rerio	57.96	7e-155	451
LLPS-Sob-0072	Sorghum bicolor	57.92	6e-146	427
LLPS-Gaa-1542	Gasterosteus aculeatus	57.92	1e-153	447
LLPS-Tag-2049	Taeniopygia guttata	57.48	3e-151	441
LLPS-Coc-0151	Corchorus capsularis	57.41	4e-143	425
LLPS-Orl-3326	Oryzias latipes	57.4	2e-154	449
LLPS-Xim-2979	Xiphophorus maculatus	57.4	3e-152	443
LLPS-Gaga-0776	Gallus gallus	57.37	2e-150	439
LLPS-Fud-1166	Fukomys damarensis	57.31	3e-135	399
LLPS-Ova-0293	Ovis aries	57.31	3e-136	401
LLPS-Mal-1006	Mandrillus leucophaeus	57.31	9e-136	400
LLPS-Tut-0231	Tursiops truncatus	57.27	3e-136	401
LLPS-Orc-0077	Oryctolagus cuniculus	57.26	1e-143	420
LLPS-Orn-2085	Oreochromis niloticus	57.14	7e-153	446
LLPS-Leo-0587	Lepisosteus oculatus	57.14	1e-150	439
LLPS-Mua-1647	Musa acuminata	57.07	2e-143	421
LLPS-Pap-0898	Pan paniscus	57.02	2e-135	399
LLPS-Sah-0473	Sarcophilus harrisii	57.02	2e-135	399
LLPS-Gog-0921	Gorilla gorilla	57.02	2e-135	399
LLPS-Pot-1474	Populus trichocarpa	56.99	1e-140	414
LLPS-Mod-1231	Monodelphis domestica	56.94	2e-136	401
LLPS-Zem-0045	Zea mays	56.83	2e-144	423
LLPS-Pes-0257	Pelodiscus sinensis	56.77	7e-138	405
LLPS-Myl-1774	Myotis lucifugus	56.77	1e-138	407
LLPS-Asm-0090	Astyanax mexicanus	56.67	2e-152	444
LLPS-Scf-1846	Scleropages formosus	56.66	4e-149	437
LLPS-Chc-0445	Chondrus crispus	56.6	1e-143	421
LLPS-Fec-0622	Felis catus	56.58	2e-148	433
LLPS-Man-1586	Macaca nemestrina	56.58	3e-148	433
LLPS-Rhb-0262	Rhinopithecus bieti	56.58	3e-148	433
LLPS-Mam-1056	Macaca mulatta	56.58	3e-148	433
LLPS-Ict-1599	Ictidomys tridecemlineatus	56.58	2e-148	433
LLPS-Anc-1102	Anolis carolinensis	56.58	1e-147	431
LLPS-Chs-0063	Chlorocebus sabaeus	56.58	3e-148	433
LLPS-Maf-0291	Macaca fascicularis	56.58	3e-148	433
LLPS-Cea-0429	Cercocebus atys	56.58	3e-148	433
LLPS-Sus-0156	Sus scrofa	56.58	2e-148	433
LLPS-Caj-2157	Callithrix jacchus	56.58	5e-148	432
LLPS-Dio-1198	Dipodomys ordii	56.58	5e-148	432
LLPS-Aim-1190	Ailuropoda melanoleuca	56.58	2e-148	433
LLPS-Paa-0237	Papio anubis	56.58	3e-148	433
LLPS-Orbr-0931	Oryza brachyantha	56.52	3e-144	422
LLPS-Sol-1004	Solanum lycopersicum	56.5	3e-140	427
LLPS-Sot-1223	Solanum tuberosum	56.5	5e-143	420
LLPS-Ten-1674	Tetraodon nigroviridis	56.48	4e-150	437
LLPS-Mup-3273	Mustela putorius furo	56.33	2e-114	344
LLPS-Pat-2120	Pan troglodytes	56.32	1e-147	431
LLPS-Loa-2096	Loxodonta africana	56.32	5e-148	432
LLPS-Eqc-0237	Equus caballus	56.32	3e-145	430
LLPS-Poa-1572	Pongo abelii	56.32	1e-147	431
LLPS-Nol-0554	Nomascus leucogenys	56.32	5e-148	432
LLPS-Aon-2134	Aotus nancymaae	56.32	6e-148	432
LLPS-Caf-1322	Canis familiaris	56.18	3e-138	407
LLPS-Mum-3460	Mus musculus	56.14	6e-148	432
LLPS-Icp-0907	Ictalurus punctatus	56.1	7e-147	429
LLPS-Hos-1310	Homo sapiens	56.05	2e-147	431
LLPS-Ran-0546	Rattus norvegicus	56.05	3e-147	431
LLPS-Ors-0426	Oryza sativa	55.98	6e-143	419
LLPS-Drm-0528	Drosophila melanogaster	55.88	1e-140	413
LLPS-Otg-1342	Otolemur garnettii	55.87	2e-148	433
LLPS-Pof-0946	Poecilia formosa	55.81	1e-145	427
LLPS-Glm-0246	Glycine max	55.73	3e-143	420
LLPS-Prp-0695	Prunus persica	55.67	2e-142	418
LLPS-Bot-0190	Bos taurus	55.52	4e-125	374
LLPS-Brd-1685	Brachypodium distachyon	55.44	3e-142	418
LLPS-Gas-0287	Galdieria sulphuraria	55.44	6e-146	427
LLPS-Tra-1129	Triticum aestivum	55.44	4e-145	425
LLPS-Chr-0269	Chlamydomonas reinhardtii	55.34	2e-137	405
LLPS-Xet-0450	Xenopus tropicalis	55.32	1e-143	421
LLPS-Hea-0160	Helianthus annuus	55.32	1e-142	419
LLPS-Phv-1362	Phaseolus vulgaris	55.2	7e-141	414
LLPS-Cus-0278	Cucumis sativus	55.05	1e-139	412
LLPS-Thc-0611	Theobroma cacao	55.03	1e-140	414
LLPS-Mae-0615	Manihot esculenta	54.89	5e-144	423
LLPS-Dac-0078	Daucus carota	54.83	1e-127	379
LLPS-Sem-0291	Selaginella moellendorffii	54.69	9e-141	414
LLPS-Php-1144	Physcomitrella patens	54.55	9e-142	417
LLPS-Hov-0818	Hordeum vulgare	54.36	3e-141	417
LLPS-Gor-0761	Gossypium raimondii	54.33	1e-142	419
LLPS-Brr-0510	Brassica rapa	54.04	7e-143	420
LLPS-Osl-0679	Ostreococcus lucimarinus	53.74	2e-103	315
LLPS-Art-0785	Arabidopsis thaliana	53.71	1e-140	414
LLPS-Arl-0179	Arabidopsis lyrata	53.69	8e-141	414
LLPS-Brn-0414	Brassica napus	53.63	3e-143	421
LLPS-Crn-0028	Cryptococcus neoformans	53.39	8e-137	405
LLPS-Via-1103	Vigna angularis	53.37	3e-127	382
LLPS-Usm-0427	Ustilago maydis	53.21	5e-116	351
LLPS-Anp-2549	Anas platyrhynchos	53.03	4e-117	352
LLPS-Sac-0088	Saccharomyces cerevisiae	52.91	1e-148	434
LLPS-Cap-2557	Cavia porcellus	52.11	8e-130	385
LLPS-Asg-0921	Ashbya gossypii	52.11	1e-145	426
LLPS-Lep-0747	Leersia perrieri	52.03	4e-125	376
LLPS-Spr-0292	Sporisorium reilianum	51.98	1e-113	345
LLPS-Cae-0853	Caenorhabditis elegans	51.7	5e-131	389
LLPS-Orp-0393	Oryza punctata	51.63	5e-121	366
LLPS-Miv-0608	Microbotryum violaceum	51.62	2e-127	380
LLPS-Cym-0199	Cyanidioschyzon merolae	51.17	1e-126	379
LLPS-Mel-0446	Melampsora laricipopulina	50.97	1e-134	400
LLPS-Pug-0119	Puccinia graminis	50.59	3e-137	406
LLPS-Put-0226	Puccinia triticina	48.32	4e-134	399
LLPS-Vir-0276	Vigna radiata	47.18	4e-111	338
LLPS-Ori-1186	Oryza indica	46.47	5e-104	318
LLPS-Bro-0841	Brassica oleracea	46.37	1e-109	334
LLPS-Viv-2457	Vitis vinifera	45.99	1e-79	255
LLPS-Orm-0288	Oryza meridionalis	45.92	2e-102	314
LLPS-Orb-1222	Oryza barthii	45.92	6e-103	316
LLPS-Orgl-0765	Oryza glumaepatula	45.92	2e-102	315
LLPS-Orr-0084	Oryza rufipogon	45.65	5e-101	311
LLPS-Orni-0589	Oryza nivara	45.65	4e-99	309
LLPS-Nia-1730	Nicotiana attenuata	45.39	2e-78	253
LLPS-Met-0176	Medicago truncatula	44.68	9e-76	246
LLPS-Org-2129	Oryza glaberrima	42.2	2e-71	234
LLPS-Lac-1881	Latimeria chalumnae	41.47	2e-75	244
LLPS-Ora-1953	Ornithorhynchus anatinus	41.46	5e-75	243

LLPS-Asc-1200ACLA_081470

Protein Sequence

Nucleotide Sequence

LLPS-Asc-1200
ACLA_081470