• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ved-0455
VDAG_01134

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Methionine aminopeptidase
Gene Name: VDAG_01134
Ensembl Gene: VDAG_01134
Ensembl Protein: EGY17452
Organism: Verticillium dahliae
Taxa ID: 498257
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEGY17452EGY17452
UniProtG2WTL1, G2WTL1_VERDV
GeneBankDS572696EGY17452.1
RefSeqXM_009650020.1XP_009648315.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAEEPPAKRK  CMGEDCSNDA  GSLQCPTCLK  VGIKDSFFCS  QDCFKKNWGT  HKSMHKSQTS  60
61    ILHHILPPSV  VSKPDPETGY  FNPFPTYPYT  GSLRPVYPLS  AKRTVPKHIP  HPDWSEDGIP  120
121   KYSRSIINRN  KAEILDAKGI  AAMRKVCRLS  REVLDIAAAA  IKPGVTTDYI  DEVVHKACIE  180
181   RDAYPSPLNY  NHFPKSVCTS  PNEVICHGIP  DQRLLMDGDI  LNIDVSLFHG  GYHGDLNETY  240
241   YVGDRAKADP  DAVRVVETAR  ECLDLSIAAV  KPGTLIREFG  NIIEKHAKAK  NCSVIRTYCG  300
301   HGINKLFHGP  PNVPHYAKNK  AVGECKPGMT  FTIEPMIALG  KYRDVTWPDN  WTSTTIDGKR  360
361   TAQFEHTLLV  TEDGVEVLTA  RTADSPGGPI  PMPEVAANGS  A  401
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGAAG  AACCCCCCGC  GAAGCGCAAG  TGCATGGGCG  AGGACTGCTC  CAACGATGCC  60
61    GGCTCTTTGC  AATGTCCAAC  GTGCCTGAAG  GTCGGCATCA  AGGACAGCTT  CTTCTGCTCG  120
121   CAGGACTGCT  TCAAGAAGAA  CTGGGGAACC  CACAAGAGCA  TGCACAAGTC  GCAGACAAGT  180
181   ATACTCCACC  ACATCCTCCC  GCCGAGCGTA  GTCTCTAAAC  CTGACCCAGA  GACCGGTTAC  240
241   TTCAACCCCT  TCCCGACCTA  CCCTTACACC  GGCTCCCTGC  GCCCCGTCTA  CCCCCTCTCC  300
301   GCAAAGCGCA  CCGTCCCGAA  ACACATCCCG  CACCCCGACT  GGTCTGAGGA  TGGTATCCCC  360
361   AAGTACAGCA  GGTCCATCAT  CAACAGGAAC  AAGGCGGAGA  TTCTCGATGC  CAAGGGCATT  420
421   GCCGCCATGC  GCAAGGTGTG  CCGGTTGTCG  CGCGAGGTCC  TCGACATTGC  GGCTGCCGCG  480
481   ATCAAGCCTG  GCGTGACAAC  CGACTACATC  GACGAGGTCG  TCCACAAGGC  GTGCATTGAA  540
541   AGAGACGCTT  ACCCTTCGCC  GCTCAACTAC  AACCACTTCC  CCAAGTCCGT  CTGCACGTCG  600
601   CCCAACGAGG  TCATCTGCCA  CGGCATTCCC  GACCAGCGCC  TTCTGATGGA  CGGCGATATC  660
661   CTCAACATTG  ACGTGTCACT  CTTCCACGGC  GGCTACCATG  GCGATCTGAA  CGAGACATAC  720
721   TACGTCGGCG  ACAGGGCCAA  GGCGGACCCG  GATGCGGTCA  GGGTTGTCGA  GACGGCGCGC  780
781   GAGTGCCTCG  ATCTTTCCAT  CGCCGCCGTC  AAGCCAGGCA  CCCTGATCCG  CGAGTTTGGC  840
841   AACATCATCG  AGAAGCACGC  CAAGGCGAAG  AACTGCAGCG  TCATTCGCAC  ATACTGTGGC  900
901   CACGGCATCA  ACAAGCTCTT  CCACGGTCCG  CCCAACGTGC  CTCACTACGC  CAAGAACAAG  960
961   GCGGTGGGCG  AGTGCAAGCC  CGGCATGACG  TTTACGATTG  AGCCCATGAT  TGCGCTTGGC  1020
1021  AAGTACCGCG  ATGTGACCTG  GCCCGACAAC  TGGACGAGCA  CGACTATTGA  CGGCAAGAGA  1080
1081  ACGGCGCAGT  TTGAACACAC  CCTGCTCGTG  ACGGAAGACG  GAGTCGAGGT  CTTGACAGCC  1140
1141  AGGACTGCGG  ACTCGCCCGG  TGGACCCATC  CCGATGCCCG  AAGTCGCGGC  AAATGGAAGC  1200
1201  GCATAG  1206

▼ KEYWORD

ID
Family
Aminopeptidase
Complete proteome
Hydrolase
Metal-binding
Protease
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Metal ion binding
Molecular Function
Metalloaminopeptidase activity
Biological Process
Protein initiator methionine removal

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cogr-0748Colletotrichum graminicola86.920.0 728
LLPS-Coo-0004Colletotrichum orbiculare85.210.0 724
LLPS-Cog-0084Colletotrichum gloeosporioides85.180.0 721
LLPS-Fus-0244Fusarium solani81.660.0 688
LLPS-Trv-1363Trichoderma virens80.550.0 695
LLPS-Trr-0555Trichoderma reesei80.050.0 694
LLPS-Beb-0556Beauveria bassiana80.050.0 661
LLPS-Mao-1044Magnaporthe oryzae78.370.0 668
LLPS-Fuo-0195Fusarium oxysporum77.860.0 655
LLPS-Fuv-0523Fusarium verticillioides77.350.0 651
LLPS-Gag-0143Gaeumannomyces graminis75.320.0 632
LLPS-Phn-0046Phaeosphaeria nodorum74.741e-160 462
LLPS-Nec-0021Neurospora crassa74.310.0 619
LLPS-Tum-0972Tuber melanosporum74.132e-142 413
LLPS-Map-0033Magnaporthe poae74.060.0 632
LLPS-Scs-0874Sclerotinia sclerotiorum73.670.0 623
LLPS-Pytr-0418Pyrenophora triticirepentis73.010.0 609
LLPS-Pyt-0572Pyrenophora teres72.660.0 611
LLPS-Asf-0343Aspergillus flavus71.980.0 607
LLPS-Aso-0501Aspergillus oryzae71.980.0 607
LLPS-Nef-0238Neosartorya fischeri71.830.0 605
LLPS-Ast-0847Aspergillus terreus71.580.0 597
LLPS-Asc-1200Aspergillus clavatus70.80.0 592
LLPS-Asn-0947Aspergillus nidulans70.740.0 597
LLPS-Zyt-0262Zymoseptoria tritici68.910.0 568
LLPS-Blg-0668Blumeria graminis68.260.0 586
LLPS-Asni-0419Aspergillus niger68.220.0 559
LLPS-Asfu-1037Aspergillus fumigatus68.140.0 595
LLPS-Lem-0193Leptosphaeria maculans67.980.0 587
LLPS-Dos-1172Dothistroma septosporum66.840.0 565
LLPS-Meg-0314Meleagris gallopavo60.982e-112 337
LLPS-Scp-0382Schizosaccharomyces pombe60.312e-163 471
LLPS-Amt-0117Amborella trichopoda59.896e-74 237
LLPS-Urm-1478Ursus maritimus59.272e-123 369
LLPS-Yal-0719Yarrowia lipolytica58.796e-159 459
LLPS-Scc-0849Schizosaccharomyces cryophilus58.666e-159 460
LLPS-Scj-0173Schizosaccharomyces japonicus58.597e-162 468
LLPS-Abg-0864Absidia glauca58.276e-147 428
LLPS-Orc-0077Oryctolagus cuniculus56.423e-139 409
LLPS-Tag-2049Taeniopygia guttata56.381e-146 429
LLPS-Gaga-0776Gallus gallus56.277e-145 424
LLPS-Dar-1374Danio rerio56.27e-149 435
LLPS-Xim-2979Xiphophorus maculatus56.175e-148 432
LLPS-Paa-0237Papio anubis56.02e-144 423
LLPS-Aim-1190Ailuropoda melanoleuca56.02e-144 423
LLPS-Dio-1198Dipodomys ordii56.03e-144 423
LLPS-Caj-2157Callithrix jacchus56.04e-144 422
LLPS-Sus-0156Sus scrofa56.02e-144 423
LLPS-Cea-0429Cercocebus atys56.02e-144 423
LLPS-Maf-0291Macaca fascicularis56.02e-144 423
LLPS-Chs-0063Chlorocebus sabaeus56.02e-144 423
LLPS-Ict-1599Ictidomys tridecemlineatus56.02e-144 423
LLPS-Mam-1056Macaca mulatta56.02e-144 423
LLPS-Eqc-0237Equus caballus56.02e-142 423
LLPS-Rhb-0262Rhinopithecus bieti56.02e-144 423
LLPS-Man-1586Macaca nemestrina56.02e-144 423
LLPS-Fec-0622Felis catus56.02e-144 423
LLPS-Myl-1774Myotis lucifugus55.915e-132 390
LLPS-Fia-0872Ficedula albicollis55.917e-133 392
LLPS-Mal-1006Mandrillus leucophaeus55.852e-128 381
LLPS-Ova-0293Ovis aries55.853e-129 383
LLPS-Poa-1572Pongo abelii55.738e-144 422
LLPS-Loa-2096Loxodonta africana55.734e-144 422
LLPS-Pat-2120Pan troglodytes55.738e-144 422
LLPS-Icp-0907Ictalurus punctatus55.75e-145 425
LLPS-Tut-0231Tursiops truncatus55.653e-128 380
LLPS-Gog-0921Gorilla gorilla55.564e-128 380
LLPS-Pap-0898Pan paniscus55.563e-128 380
LLPS-Sah-0473Sarcophilus harrisii55.493e-128 380
LLPS-Ran-0546Rattus norvegicus55.476e-143 419
LLPS-Aon-2134Aotus nancymaae55.472e-143 421
LLPS-Nol-0554Nomascus leucogenys55.471e-143 421
LLPS-Anc-1102Anolis carolinensis55.471e-144 424
LLPS-Otg-1342Otolemur garnettii55.472e-143 421
LLPS-Hos-1310Homo sapiens55.471e-143 421
LLPS-Asm-0090Astyanax mexicanus55.447e-147 430
LLPS-Mum-3460Mus musculus55.412e-143 421
LLPS-Gaa-1542Gasterosteus aculeatus55.383e-144 423
LLPS-Orl-3326Oryzias latipes55.383e-148 434
LLPS-Scm-2983Scophthalmus maximus55.148e-132 390
LLPS-Mod-1231Monodelphis domestica55.131e-128 381
LLPS-Kop-0430Komagataella pastoris54.972e-149 435
LLPS-Fud-1166Fukomys damarensis54.973e-127 379
LLPS-Leo-0587Lepisosteus oculatus54.952e-145 426
LLPS-Scf-1846Scleropages formosus54.884e-143 422
LLPS-Pof-0946Poecilia formosa54.833e-144 423
LLPS-Pes-0257Pelodiscus sinensis54.761e-129 384
LLPS-Ten-1674Tetraodon nigroviridis54.715e-145 424
LLPS-Bot-0190Bos taurus54.687e-120 360
LLPS-Orn-2085Oreochromis niloticus54.591e-144 425
LLPS-Mup-3273Mustela putorius furo54.493e-106 323
LLPS-Caf-1322Canis familiaris54.494e-132 392
LLPS-Tru-0409Triticum urartu54.425e-105 320
LLPS-Tar-0970Takifugu rubripes54.237e-102 310
LLPS-Chc-0445Chondrus crispus54.075e-134 396
LLPS-Asg-0921Ashbya gossypii53.786e-140 411
LLPS-Tra-2976Triticum aestivum53.644e-130 387
LLPS-Coc-0151Corchorus capsularis53.648e-130 391
LLPS-Cus-0278Cucumis sativus53.561e-130 388
LLPS-Xet-0450Xenopus tropicalis53.43e-137 405
LLPS-Gor-0761Gossypium raimondii53.265e-133 395
LLPS-Hea-0160Helianthus annuus53.194e-129 384
LLPS-Brn-0414Brassica napus53.193e-128 382
LLPS-Brr-0510Brassica rapa53.194e-128 382
LLPS-Sol-1004Solanum lycopersicum53.052e-127 393
LLPS-Thc-0611Theobroma cacao52.934e-130 387
LLPS-Sot-1223Solanum tuberosum52.868e-132 392
LLPS-Art-0785Arabidopsis thaliana52.832e-126 378
LLPS-Sob-0072Sorghum bicolor52.722e-130 388
LLPS-Orbr-0931Oryza brachyantha52.729e-130 386
LLPS-Ors-0426Oryza sativa52.722e-129 385
LLPS-Sei-0819Setaria italica52.532e-128 382
LLPS-Sac-0088Saccharomyces cerevisiae52.471e-143 421
LLPS-Zem-0045Zea mays52.451e-129 386
LLPS-Gas-0287Galdieria sulphuraria52.324e-135 399
LLPS-Sem-1451Selaginella moellendorffii52.22e-129 385
LLPS-Brd-1685Brachypodium distachyon52.179e-128 381
LLPS-Chr-0269Chlamydomonas reinhardtii52.162e-123 370
LLPS-Mua-0381Musa acuminata52.133e-127 380
LLPS-Via-1103Vigna angularis52.16e-122 368
LLPS-Arl-0179Arabidopsis lyrata52.018e-126 376
LLPS-Usm-0427Ustilago maydis51.93e-104 320
LLPS-Pot-1474Populus trichocarpa51.882e-125 375
LLPS-Osl-0679Ostreococcus lucimarinus51.61e-93 289
LLPS-Mae-0615Manihot esculenta51.577e-130 387
LLPS-Cap-2557Cavia porcellus51.471e-125 374
LLPS-Hov-0818Hordeum vulgare51.462e-125 377
LLPS-Dac-0078Daucus carota51.421e-117 353
LLPS-Anp-2549Anas platyrhynchos51.169e-110 333
LLPS-Prp-0695Prunus persica51.157e-131 389
LLPS-Phv-1362Phaseolus vulgaris51.063e-129 385
LLPS-Miv-0608Microbotryum violaceum50.933e-116 352
LLPS-Php-2266Physcomitrella patens50.91e-129 386
LLPS-Glm-0246Glycine max50.793e-130 387
LLPS-Lep-0747Leersia perrieri50.721e-111 341
LLPS-Crn-0028Cryptococcus neoformans50.673e-126 378
LLPS-Spr-0292Sporisorium reilianum50.313e-103 318
LLPS-Cae-0853Caenorhabditis elegans50.03e-123 369
LLPS-Mel-0446Melampsora laricipopulina49.043e-125 375
LLPS-Drm-0528Drosophila melanogaster48.971e-125 375
LLPS-Pug-0119Puccinia graminis48.565e-125 375
LLPS-Cym-0199Cyanidioschyzon merolae48.212e-116 353
LLPS-Orp-0393Oryza punctata47.553e-108 333
LLPS-Met-0176Medicago truncatula46.963e-73 239
LLPS-Put-0226Puccinia triticina46.171e-120 365
LLPS-Nia-1730Nicotiana attenuata46.11e-77 251
LLPS-Bro-0841Brassica oleracea45.744e-97 302
LLPS-Ori-1186Oryza indica44.573e-95 296
LLPS-Viv-2015Vitis vinifera44.334e-76 247
LLPS-Cii-0531Ciona intestinalis44.02e-70 229
LLPS-Ora-1953Ornithorhynchus anatinus43.973e-73 238
LLPS-Orgl-0607Oryza glumaepatula43.124e-71 233
LLPS-Orb-0206Oryza barthii43.127e-71 233
LLPS-Org-2129Oryza glaberrima43.124e-71 233
LLPS-Orm-1323Oryza meridionalis43.122e-70 233
LLPS-Vir-0276Vigna radiata43.04e-100 310
LLPS-Cas-3474Carlito syrichta42.914e-69 228
LLPS-Orni-0589Oryza nivara42.396e-87 278
LLPS-Orr-0084Oryza rufipogon42.392e-88 279
LLPS-Lac-1881Latimeria chalumnae41.941e-73 239