DrLLPS - Data resource of LLPS

LLPS-Usm-0517
UMAG_04371

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Eukaryotic translation initiation factor 2A
Gene Name:	UMAG_04371
Ensembl Gene:	UMAG_04371
Ensembl Protein:	KIS67268
Organism:	Ustilago maydis
Taxa ID:	237631
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Arabidopsis thaliana	LLPS-Art-0842	Q9CAT3	Client	Nucleolus	34.03	1e-75	257
Homo sapiens	LLPS-Hos-1098	Q9BY44	Client	Nucleolus, Stress granule	33.97	8e-77	262

▼ FUNCTION

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	KIS67268	KIS67268
UniProt		A0A0D1CK95, A0A0D1CK95_USTMA
GeneBank	CM003153	KIS67268.1
RefSeq	XM_011392773.1	XP_011391075.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSEPSAVSVA VGEPTTQWAY RAQKSIGLNT GSPSYTSVSG FDQVTGATRV FQYSPDGSTF 60 61 AAAMDDFTRL VDTRAASTSS VKRDLPVPKV VDLQFSPRGA FLSTWERPSK LDDGSNARNL 120 121 KMWDTETGET VAAFERKSQE GCFFQFTANE QYCVRQVSTE LQIYEPRHIT DKGVIGRLRL 180 181 EGITSFEVGP GDKPSIAVFC GEKKGAPASV RVYSLASLIP CPESPPAPVS QKTFFKADKI 240 241 QIKWNKAGSA LLFMTSTDHD KTGKSYYGET NLYLMSVRGD FDCRVALDKE GPIHDFEWNP 300 301 NSKEFIVIYG YMPAKAVLFS HRVNVIAELG TQPRNFVAFN PQGRLFCIAG FGNLSGTVDV 360 361 WDRQELSKGK IFSMDASNSS VCQWSPDGHF LLTATLSPRL RVENGVKIWH CTGQLVHVDM 420 421 IDELYQAGWR PGSNAGLVAF PAQIPSAPAA SAAAASYLAT KAATKRPTGT YRPPGARGQG 480 481 TPDIYKRIDE GGSGASTPDL ARSGSQNGTY QAPGSGNRKR AIPGAPGSAP RTNGNAATNQ 540 541 KDGKKKGGKQ QQNGKNANAA SASVTVVEES AGTASSGAAE VGGNSSAANL EKKVRNLNKK 600 601 LKAIEELKLR QAGGEKLEAM QLAKIAAEQE VRRDLATLE 639

Protein Sequence (FASTA)

1     MSEPSAVSVA  VGEPTTQWAY  RAQKSIGLNT  GSPSYTSVSG  FDQVTGATRV  FQYSPDGSTF  60
61    AAAMDDFTRL  VDTRAASTSS  VKRDLPVPKV  VDLQFSPRGA  FLSTWERPSK  LDDGSNARNL  120
121   KMWDTETGET  VAAFERKSQE  GCFFQFTANE  QYCVRQVSTE  LQIYEPRHIT  DKGVIGRLRL  180
181   EGITSFEVGP  GDKPSIAVFC  GEKKGAPASV  RVYSLASLIP  CPESPPAPVS  QKTFFKADKI  240
241   QIKWNKAGSA  LLFMTSTDHD  KTGKSYYGET  NLYLMSVRGD  FDCRVALDKE  GPIHDFEWNP  300
301   NSKEFIVIYG  YMPAKAVLFS  HRVNVIAELG  TQPRNFVAFN  PQGRLFCIAG  FGNLSGTVDV  360
361   WDRQELSKGK  IFSMDASNSS  VCQWSPDGHF  LLTATLSPRL  RVENGVKIWH  CTGQLVHVDM  420
421   IDELYQAGWR  PGSNAGLVAF  PAQIPSAPAA  SAAAASYLAT  KAATKRPTGT  YRPPGARGQG  480
481   TPDIYKRIDE  GGSGASTPDL  ARSGSQNGTY  QAPGSGNRKR  AIPGAPGSAP  RTNGNAATNQ  540
541   KDGKKKGGKQ  QQNGKNANAA  SASVTVVEES  AGTASSGAAE  VGGNSSAANL  EKKVRNLNKK  600
601   LKAIEELKLR  QAGGEKLEAM  QLAKIAAEQE  VRRDLATLE  639

▼ KEYWORD

ID	Family
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-0396	Initiation factor
KW-0648	Protein biosynthesis
KW-1185	Reference proteome
KW-0810	Translation regulation

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0022627	Cellular Component	Cytosolic small ribosomal subunit
GO:0043022	Molecular Function	Ribosome binding
GO:0003743	Molecular Function	Translation initiation factor activity
GO:0000049	Molecular Function	TRNA binding
GO:0006417	Biological Process	Regulation of translation

▼ KEGG

uma:UMAG_04371

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Spr-0395	Sporisorium reilianum	88.59	0.0	1073
LLPS-Zyt-1347	Zymoseptoria tritici	62.22	8e-09	62.8
LLPS-Aso-0917	Aspergillus oryzae	60.42	2e-08	61.6
LLPS-Asf-0741	Aspergillus flavus	60.42	2e-08	61.6
LLPS-Dos-1129	Dothistroma septosporum	60.42	5e-09	63.5
LLPS-Asc-0510	Aspergillus clavatus	58.33	1e-07	58.9
LLPS-Tum-1109	Tuber melanosporum	58.33	5e-07	57.0
LLPS-Scj-1014	Schizosaccharomyces japonicus	58.33	1e-06	55.5
LLPS-Nef-0610	Neosartorya fischeri	58.33	1e-07	58.9
LLPS-Asni-0305	Aspergillus niger	56.25	2e-07	58.5
LLPS-Asn-0664	Aspergillus nidulans	56.25	2e-07	58.2
LLPS-Lem-0526	Leptosphaeria maculans	56.25	2e-08	62.0
LLPS-Nec-1234	Neurospora crassa	56.25	3e-07	57.8
LLPS-Ast-0276	Aspergillus terreus	56.25	3e-07	58.2
LLPS-Phn-1209	Phaeosphaeria nodorum	56.25	8e-09	62.8
LLPS-Asfu-0529	Aspergillus fumigatus	56.25	1e-06	56.2
LLPS-Coo-0901	Colletotrichum orbiculare	54.17	2e-06	55.5
LLPS-Asg-1281	Ashbya gossypii	52.73	9e-07	56.2
LLPS-Pyt-1032	Pyrenophora teres	52.08	4e-07	57.4
LLPS-Pytr-0733	Pyrenophora triticirepentis	52.08	5e-07	57.4
LLPS-Cogr-0558	Colletotrichum graminicola	52.08	2e-06	55.1
LLPS-Ved-0585	Verticillium dahliae	52.08	2e-06	55.1
LLPS-Gag-1578	Gaeumannomyces graminis	51.85	3e-06	54.7
LLPS-Map-0999	Magnaporthe poae	51.85	2e-06	55.5
LLPS-Put-0485	Puccinia triticina	49.49	2e-154	466
LLPS-Pug-0773	Puccinia graminis	47.52	6e-161	484
LLPS-Poa-2392	Pongo abelii	46.35	4e-50	183
LLPS-Mae-1567	Manihot esculenta	45.9	1e-30	124
LLPS-Trr-0090	Trichoderma reesei	45.35	1e-139	430
LLPS-Miv-0311	Microbotryum violaceum	45.31	7e-163	488
LLPS-Trv-1305	Trichoderma virens	45.16	2e-139	430
LLPS-Scc-0194	Schizosaccharomyces cryophilus	44.73	7e-140	427
LLPS-Scp-0720	Schizosaccharomyces pombe	44.53	1e-139	426
LLPS-Beb-0118	Beauveria bassiana	44.51	7e-138	426
LLPS-Fus-1263	Fusarium solani	44.17	4e-137	424
LLPS-Blg-0290	Blumeria graminis	43.93	4e-138	427
LLPS-Mel-0714	Melampsora laricipopulina	43.91	6e-171	509
LLPS-Fuv-0728	Fusarium verticillioides	43.52	1e-136	422
LLPS-Mao-1005	Magnaporthe oryzae	43.02	9e-134	416
LLPS-Fuo-0394	Fusarium oxysporum	42.94	1e-135	419
LLPS-Sah-0156	Sarcophilus harrisii	41.32	3e-67	233
LLPS-Ora-2022	Ornithorhynchus anatinus	40.43	7e-75	254
LLPS-Kop-0043	Komagataella pastoris	39.16	6e-126	392
LLPS-Abg-0217	Absidia glauca	38.76	3e-137	419
LLPS-Cap-2093	Cavia porcellus	38.6	6e-72	248
LLPS-Meg-0509	Meleagris gallopavo	38.3	2e-83	280
LLPS-Glm-1418	Glycine max	37.6	4e-80	270
LLPS-Scf-2026	Scleropages formosus	37.53	4e-86	287
LLPS-Yal-0466	Yarrowia lipolytica	37.38	9e-118	369
LLPS-Scm-3399	Scophthalmus maximus	37.32	1e-83	281
LLPS-Lac-1244	Latimeria chalumnae	37.23	2e-83	280
LLPS-Sem-1001	Selaginella moellendorffii	37.17	2e-78	266
LLPS-Met-1084	Medicago truncatula	37.14	1e-82	276
LLPS-Viv-1630	Vitis vinifera	37.14	2e-81	275
LLPS-Phv-0223	Phaseolus vulgaris	37.14	2e-78	265
LLPS-Mal-2407	Mandrillus leucophaeus	37.01	1e-83	280
LLPS-Ere-0360	Erinaceus europaeus	37.01	9e-84	281
LLPS-Anc-2178	Anolis carolinensis	36.98	1e-89	296
LLPS-Gaga-1450	Gallus gallus	36.92	7e-88	292
LLPS-Leo-1029	Lepisosteus oculatus	36.85	8e-86	286
LLPS-Tar-0749	Takifugu rubripes	36.85	3e-85	283
LLPS-Gaa-0311	Gasterosteus aculeatus	36.82	7e-81	273
LLPS-Via-1414	Vigna angularis	36.77	2e-74	256
LLPS-Man-1256	Macaca nemestrina	36.75	3e-83	279
LLPS-Hea-0048	Helianthus annuus	36.72	1e-78	264
LLPS-Fud-1811	Fukomys damarensis	36.6	2e-83	280
LLPS-Ict-1757	Ictidomys tridecemlineatus	36.6	1e-83	280
LLPS-Drm-0549	Drosophila melanogaster	36.55	3e-72	251
LLPS-Xet-0103	Xenopus tropicalis	36.45	2e-85	285
LLPS-Mod-2475	Monodelphis domestica	36.43	8e-84	281
LLPS-Pes-2100	Pelodiscus sinensis	36.43	2e-80	272
LLPS-Dar-0056	Danio rerio	36.41	5e-83	279
LLPS-Crn-0711	Cryptococcus neoformans	36.36	3e-116	368
LLPS-Chs-2297	Chlorocebus sabaeus	36.36	4e-84	282
LLPS-Maf-1188	Macaca fascicularis	36.36	3e-83	280
LLPS-Myl-0740	Myotis lucifugus	36.36	5e-84	281
LLPS-Fec-1285	Felis catus	36.36	6e-85	284
LLPS-Orc-0232	Oryctolagus cuniculus	36.36	3e-82	277
LLPS-Otg-2228	Otolemur garnettii	36.36	8e-84	281
LLPS-Mam-0650	Macaca mulatta	36.36	2e-83	280
LLPS-Caf-1937	Canis familiaris	36.36	5e-84	281
LLPS-Ten-2047	Tetraodon nigroviridis	36.36	3e-85	285
LLPS-Tag-1469	Taeniopygia guttata	36.34	2e-81	275
LLPS-Paa-2669	Papio anubis	36.28	2e-84	283
LLPS-Php-2179	Physcomitrella patens	36.15	4e-82	275
LLPS-Sus-1732	Sus scrofa	36.12	2e-83	280
LLPS-Gog-1431	Gorilla gorilla	36.12	1e-83	280
LLPS-Ova-1414	Ovis aries	36.12	8e-84	281
LLPS-Aim-1128	Ailuropoda melanoleuca	36.12	9e-84	281
LLPS-Mup-1383	Mustela putorius furo	36.12	9e-84	281
LLPS-Pap-3474	Pan paniscus	36.12	1e-83	280
LLPS-Pat-0227	Pan troglodytes	36.12	2e-83	280
LLPS-Cas-0128	Carlito syrichta	36.12	6e-84	281
LLPS-Anp-1931	Anas platyrhynchos	36.02	1e-84	283
LLPS-Icp-2538	Ictalurus punctatus	35.93	6e-82	276
LLPS-Bot-0575	Bos taurus	35.93	1e-83	281
LLPS-Nol-4023	Nomascus leucogenys	35.93	9e-82	276
LLPS-Aon-1320	Aotus nancymaae	35.89	4e-83	279
LLPS-Caj-1871	Callithrix jacchus	35.89	3e-83	280
LLPS-Ran-4017	Rattus norvegicus	35.89	7e-83	279
LLPS-Loa-1647	Loxodonta africana	35.89	2e-82	277
LLPS-Urm-0486	Ursus maritimus	35.89	2e-83	280
LLPS-Hos-1098	Homo sapiens	35.89	4e-81	274
LLPS-Rhb-0761	Rhinopithecus bieti	35.89	3e-82	277
LLPS-Eqc-2604	Equus caballus	35.89	2e-83	280
LLPS-Fia-2096	Ficedula albicollis	35.87	9e-83	278
LLPS-Org-1053	Oryza glaberrima	35.85	5e-74	253
LLPS-Pot-1788	Populus trichocarpa	35.84	6e-81	271
LLPS-Mea-0574	Mesocricetus auratus	35.65	2e-82	277
LLPS-Mum-3758	Mus musculus	35.65	4e-82	276
LLPS-Prp-0644	Prunus persica	35.58	1e-79	268
LLPS-Orn-0031	Oreochromis niloticus	35.53	3e-80	271
LLPS-Sei-0293	Setaria italica	35.51	3e-76	259
LLPS-Pof-3456	Poecilia formosa	35.45	1e-77	265
LLPS-Gor-1840	Gossypium raimondii	35.32	9e-76	258
LLPS-Ori-1721	Oryza indica	35.25	9e-75	255
LLPS-Xim-1207	Xiphophorus maculatus	35.21	6e-79	268
LLPS-Gas-0192	Galdieria sulphuraria	35.16	1e-58	213
LLPS-Orbr-1842	Oryza brachyantha	35.16	1e-73	252
LLPS-Osl-0862	Ostreococcus lucimarinus	35.09	1e-75	258
LLPS-Brr-1916	Brassica rapa	35.06	1e-76	260
LLPS-Cea-0546	Cercocebus atys	35.01	5e-77	263
LLPS-Sob-1491	Sorghum bicolor	35.01	3e-73	251
LLPS-Coc-0757	Corchorus capsularis	35.01	5e-73	258
LLPS-Tra-0596	Triticum aestivum	34.9	8e-74	253
LLPS-Zem-1962	Zea mays	34.75	8e-72	247
LLPS-Amt-0662	Amborella trichopoda	34.64	4e-77	261
LLPS-Chr-1218	Chlamydomonas reinhardtii	34.57	2e-61	221
LLPS-Dio-2357	Dipodomys ordii	34.49	1e-70	244
LLPS-Sol-1593	Solanum lycopersicum	34.42	1e-78	266
LLPS-Hov-1140	Hordeum vulgare	34.38	2e-71	246
LLPS-Brn-2169	Brassica napus	34.29	4e-76	258
LLPS-Bro-1206	Brassica oleracea	34.29	6e-76	259
LLPS-Lep-1595	Leersia perrieri	34.2	1e-69	241
LLPS-Mua-0159	Musa acuminata	34.03	1e-75	257
LLPS-Art-0842	Arabidopsis thaliana	34.03	1e-75	257
LLPS-Asm-2345	Astyanax mexicanus	34.02	9e-87	289
LLPS-Arl-0622	Arabidopsis lyrata	33.77	3e-76	259
LLPS-Cus-1816	Cucumis sativus	33.72	4e-79	267
LLPS-Brd-0607	Brachypodium distachyon	33.48	1e-75	258
LLPS-Cis-1391	Ciona savignyi	33.33	4e-60	216
LLPS-Chc-0787	Chondrus crispus	33.07	2e-34	139
LLPS-Cae-2015	Caenorhabditis elegans	32.91	1e-63	226
LLPS-Dac-2298	Daucus carota	32.91	2e-36	143
LLPS-Sac-1128	Saccharomyces cerevisiae	32.9	1e-82	280
LLPS-Cym-0683	Cyanidioschyzon merolae	32.55	2e-52	196
LLPS-Orb-0661	Oryza barthii	32.49	1e-55	202
LLPS-Orgl-1272	Oryza glumaepatula	32.11	4e-55	201
LLPS-Cii-0146	Ciona intestinalis	32.1	2e-67	237
LLPS-Orni-0922	Oryza nivara	31.85	1e-54	199
LLPS-Vir-0445	Vigna radiata	31.85	8e-58	211
LLPS-Orr-0132	Oryza rufipogon	31.85	2e-54	199
LLPS-Orm-0391	Oryza meridionalis	31.85	2e-54	199
LLPS-Thc-0940	Theobroma cacao	31.62	7e-68	237
LLPS-Orp-0387	Oryza punctata	31.59	9e-54	197
LLPS-Tru-0970	Triticum urartu	28.61	5e-40	157
LLPS-Sot-0194	Solanum tuberosum	25.81	2e-18	94.0
LLPS-Orl-0631	Oryzias latipes	23.28	1e-18	94.4

LLPS-Usm-0517UMAG_04371

Protein Sequence

Nucleotide Sequence

LLPS-Usm-0517
UMAG_04371