LLPS-Coo-0901
Cob_06040
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Eukaryotic translation initiation factor 2A |
| Gene Name: | Cob_06040 |
| Ensembl Gene: | Cob_06040 |
| Ensembl Protein: | ENH85820 |
| Organism: | Colletotrichum orbiculare |
| Taxa ID: | 1213857 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENH85820 | ENH85820 |
| UniProt | N4VTU1, N4VTU1_COLOR | |
| GeneBank | KB725767 | ENH85820.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MASSSLQFAY RTQKGIGLFD AAPAYQPLAG FNKPEGNLRC CAYSPCGRYF AWASPEVVTV 60 61 VDASTGSEVL ALPILNVYEL GFSPLGNFIV TWERPAKDEN GDATKNLKVW RTVEDGVAAA 120 121 DKLPVGKFVQ KNQRDWNLQY TDDEKFCARQ VTNEIQFYES HDLGTVWNKL RVEGVADFAL 180 181 APGKSHSVAV FVPERKGQPA AVKVFNVPQF TSPISQKTFF KGDKVQLKWN KLGTSILVLA 240 241 QTEVDKSNKS YYGETTLYLL SVNGAFDARI TLDKEGPIHD VSWSPNSKEF GVVYGYMPAK 300 301 ATIFNHRAVA THSFPLGPRN TIIFSPTGRF ALVAGFGNLA GQIDVYDLEK DFRKLHTIES 360 361 GNPSVCTWSP DSRYIMTATT SPRLRVDNGV KLWHVTGPLM YSEDMVELYT VLVRPQAAEK 420 421 VAGGDPLNPV PTPHASATTY LGSVKTPSKP AGAYRPPGAR GNATPLHFKR EDEGGAAHVS 480 481 MPNGTAPIGP NGFGRPRRAV PGAEPVPGSN PRVPGADTAD ADENLSKAAL KNKKKRNNKK 540 541 KEGDANPEGQ NGGGASLAPP PRDFGSGSGH EGRSPERRGG AGANNRHRSH SRNPGAPRNR 600 601 SNTHRQNGAP QLPNAHGQAA AVNNAAADNS QNPNAKKVRS LQKKVRAIED LEMRLAGGEK 660 661 LEETQMKKIN TKSSVLKELE VLEKEGH 687 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGTCCT CATCTTTGCA GTTTGCCTAC CGAACCCAGA AGGGCATCGG CCTGTTTGAT 60 61 GCTGCCCCGG CCTACCAGCC GCTCGCTGGG TTCAACAAGC CCGAAGGGAA CCTCCGGTGT 120 121 TGTGCCTACT CGCCCTGTGG CCGCTATTTT GCCTGGGCCA GCCCCGAGGT CGTCACTGTT 180 181 GTTGACGCCT CTACCGGCTC CGAGGTTCTT GCCCTGCCCA TCCTCAACGT CTACGAGCTC 240 241 GGTTTTTCTC CCCTAGGTAA CTTCATCGTC ACATGGGAGC GCCCCGCCAA GGACGAGAAT 300 301 GGAGACGCAA CCAAGAACCT GAAGGTATGG CGCACCGTCG AGGACGGTGT CGCCGCCGCC 360 361 GACAAGCTGC CTGTGGGCAA GTTTGTCCAG AAGAATCAGA GGGACTGGAA CCTTCAGTAC 420 421 ACGGACGACG AGAAGTTCTG CGCCCGCCAG GTCACCAACG AAATTCAGTT TTACGAGAGC 480 481 CACGATCTCG GTACCGTCTG GAACAAGTTG AGAGTCGAGG GTGTCGCCGA CTTTGCTCTG 540 541 GCCCCTGGCA AATCTCACTC TGTTGCCGTC TTCGTCCCCG AACGCAAGGG CCAACCCGCT 600 601 GCTGTCAAGG TCTTCAACGT CCCCCAGTTC ACCTCGCCCA TCTCTCAAAA GACATTCTTC 660 661 AAGGGTGACA AGGTCCAGCT CAAGTGGAAC AAGTTGGGGA CTAGCATCCT CGTCCTGGCT 720 721 CAGACCGAAG TGGACAAGTC TAACAAGAGC TACTACGGCG AGACGACGCT CTACCTGCTC 780 781 AGCGTCAACG GTGCTTTTGA CGCTCGCATC ACCCTTGACA AGGAGGGCCC CATTCACGAC 840 841 GTGTCCTGGT CTCCGAACTC GAAGGAGTTT GGTGTCGTGT ATGGATATAT GCCCGCCAAG 900 901 GCCACCATCT TCAACCACCG CGCCGTTGCG ACCCACTCGT TCCCCCTCGG GCCCCGTAAC 960 961 ACCATAATTT TCTCGCCTAC TGGCCGCTTC GCTCTGGTCG CCGGCTTTGG TAATCTGGCT 1020 1021 GGCCAGATTG ACGTTTACGA TCTCGAGAAG GATTTCCGCA AGCTGCACAC CATCGAGAGC 1080 1081 GGAAACCCCA GCGTTTGCAC CTGGAGCCCG GACAGCCGCT ATATCATGAC GGCCACCACG 1140 1141 TCTCCTCGTC TCCGCGTCGA TAACGGCGTC AAGCTGTGGC ACGTCACTGG CCCACTCATG 1200 1201 TACAGCGAAG ATATGGTTGA GTTGTACACG GTCCTTGTCA GACCCCAGGC CGCGGAAAAA 1260 1261 GTGGCCGGAG GTGATCCTCT GAACCCTGTG CCCACCCCGC ACGCATCTGC TACCACCTAT 1320 1321 CTTGGCTCTG TTAAGACGCC GAGCAAGCCA GCTGGAGCCT ACCGCCCCCC TGGTGCTCGT 1380 1381 GGCAACGCCA CACCTCTTCA CTTCAAGCGG GAGGATGAGG GCGGCGCAGC CCACGTGAGC 1440 1441 ATGCCCAACG GAACGGCGCC TATCGGACCT AACGGATTCG GCCGCCCCCG CCGTGCTGTG 1500 1501 CCCGGTGCCG AGCCTGTTCC CGGCTCCAAC CCGAGAGTTC CCGGAGCTGA CACCGCCGAT 1560 1561 GCCGATGAAA ACTTGTCAAA GGCGGCGCTC AAGAACAAGA AGAAACGTAA CAACAAAAAG 1620 1621 AAGGAGGGCG ACGCCAACCC CGAGGGCCAG AATGGCGGTG GTGCCTCGCT GGCCCCGCCC 1680 1681 CCGCGTGACT TTGGATCCGG ATCTGGCCAC GAAGGTCGTA GCCCTGAGCG TCGTGGCGGC 1740 1741 GCCGGAGCTA ACAACAGGCA CCGCAGCCAC TCTCGGAACC CGGGTGCGCC TCGTAACAGG 1800 1801 AGCAACACCC ACCGTCAGAA CGGGGCGCCC CAGCTGCCTA ATGCGCACGG TCAGGCCGCC 1860 1861 GCCGTCAACA ACGCCGCCGC CGACAACTCG CAGAACCCAA ACGCGAAGAA AGTTCGCAGC 1920 1921 CTGCAGAAGA AGGTGCGCGC CATTGAGGAT CTCGAGATGA GGCTCGCTGG CGGAGAGAAG 1980 1981 CTCGAAGAGA CCCAGATGAA GAAGATTAAC ACCAAGTCTT CTGTGCTCAA GGAGCTTGAA 2040 2041 GTCCTCGAGA AGGAGGGCCA CTGA 2064 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Molecular Function | Translation initiation factor activity | |
Biological Process | Regulation of translation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Cogr-0558 | Colletotrichum graminicola | 87.12 | 0.0 | 1129 |
| LLPS-Ved-0585 | Verticillium dahliae | 80.87 | 0.0 | 871 |
| LLPS-Fuo-0394 | Fusarium oxysporum | 75.78 | 0.0 | 974 |
| LLPS-Fus-1263 | Fusarium solani | 75.29 | 0.0 | 989 |
| LLPS-Asni-0305 | Aspergillus niger | 75.0 | 6e-08 | 60.1 |
| LLPS-Fuv-0728 | Fusarium verticillioides | 74.63 | 0.0 | 967 |
| LLPS-Beb-0118 | Beauveria bassiana | 73.45 | 0.0 | 954 |
| LLPS-Nec-1234 | Neurospora crassa | 72.3 | 0.0 | 900 |
| LLPS-Trr-0090 | Trichoderma reesei | 71.7 | 0.0 | 931 |
| LLPS-Trv-1305 | Trichoderma virens | 71.51 | 0.0 | 938 |
| LLPS-Gag-1578 | Gaeumannomyces graminis | 69.55 | 0.0 | 889 |
| LLPS-Map-0999 | Magnaporthe poae | 69.02 | 0.0 | 885 |
| LLPS-Mao-1005 | Magnaporthe oryzae | 66.19 | 0.0 | 884 |
| LLPS-Blg-0290 | Blumeria graminis | 64.08 | 0.0 | 834 |
| LLPS-Asc-0510 | Aspergillus clavatus | 59.8 | 0.0 | 764 |
| LLPS-Asfu-0529 | Aspergillus fumigatus | 59.74 | 0.0 | 775 |
| LLPS-Nef-0610 | Neosartorya fischeri | 59.3 | 0.0 | 778 |
| LLPS-Phn-1209 | Phaeosphaeria nodorum | 58.37 | 0.0 | 776 |
| LLPS-Aso-0917 | Aspergillus oryzae | 58.27 | 0.0 | 762 |
| LLPS-Ast-0276 | Aspergillus terreus | 58.22 | 0.0 | 761 |
| LLPS-Asf-0741 | Aspergillus flavus | 57.99 | 0.0 | 724 |
| LLPS-Lem-0526 | Leptosphaeria maculans | 57.97 | 0.0 | 773 |
| LLPS-Pyt-1032 | Pyrenophora teres | 57.63 | 0.0 | 771 |
| LLPS-Asn-0664 | Aspergillus nidulans | 57.16 | 0.0 | 751 |
| LLPS-Pytr-0733 | Pyrenophora triticirepentis | 56.47 | 0.0 | 770 |
| LLPS-Scc-0194 | Schizosaccharomyces cryophilus | 52.85 | 0.0 | 537 |
| LLPS-Tum-1109 | Tuber melanosporum | 52.19 | 0.0 | 639 |
| LLPS-Scj-1014 | Schizosaccharomyces japonicus | 51.27 | 1e-174 | 518 |
| LLPS-Scp-0720 | Schizosaccharomyces pombe | 50.58 | 4e-174 | 517 |
| LLPS-Yal-0466 | Yarrowia lipolytica | 50.1 | 1e-155 | 469 |
| LLPS-Pug-0773 | Puccinia graminis | 48.17 | 1e-148 | 454 |
| LLPS-Put-0485 | Puccinia triticina | 47.24 | 3e-138 | 426 |
| LLPS-Mel-0714 | Melampsora laricipopulina | 46.76 | 7e-143 | 439 |
| LLPS-Miv-0311 | Microbotryum violaceum | 45.61 | 2e-143 | 439 |
| LLPS-Spr-0395 | Sporisorium reilianum | 45.47 | 2e-143 | 441 |
| LLPS-Usm-0517 | Ustilago maydis | 45.32 | 2e-144 | 442 |
| LLPS-Abg-0217 | Absidia glauca | 44.03 | 4e-125 | 389 |
| LLPS-Ora-2022 | Ornithorhynchus anatinus | 42.73 | 1e-83 | 279 |
| LLPS-Kop-0043 | Komagataella pastoris | 42.61 | 2e-137 | 424 |
| LLPS-Poa-2392 | Pongo abelii | 42.19 | 1e-49 | 182 |
| LLPS-Sah-0156 | Sarcophilus harrisii | 41.45 | 2e-78 | 264 |
| LLPS-Orn-0031 | Oreochromis niloticus | 40.42 | 7e-103 | 333 |
| LLPS-Dar-0056 | Danio rerio | 39.74 | 6e-100 | 325 |
| LLPS-Pof-3456 | Poecilia formosa | 39.7 | 2e-97 | 318 |
| LLPS-Icp-2538 | Ictalurus punctatus | 39.67 | 2e-100 | 326 |
| LLPS-Cap-2093 | Cavia porcellus | 39.63 | 2e-82 | 277 |
| LLPS-Scm-3399 | Scophthalmus maximus | 39.42 | 1e-98 | 322 |
| LLPS-Gaa-0311 | Gasterosteus aculeatus | 39.41 | 1e-92 | 305 |
| LLPS-Via-1414 | Vigna angularis | 39.39 | 3e-75 | 259 |
| LLPS-Org-1053 | Oryza glaberrima | 39.03 | 3e-74 | 255 |
| LLPS-Lac-1244 | Latimeria chalumnae | 39.02 | 1e-96 | 316 |
| LLPS-Ten-2047 | Tetraodon nigroviridis | 39.01 | 2e-99 | 325 |
| LLPS-Chc-0787 | Chondrus crispus | 38.93 | 2e-40 | 155 |
| LLPS-Tar-0749 | Takifugu rubripes | 38.89 | 1e-95 | 313 |
| LLPS-Xim-1207 | Xiphophorus maculatus | 38.77 | 8e-96 | 314 |
| LLPS-Asm-2345 | Astyanax mexicanus | 38.51 | 1e-97 | 319 |
| LLPS-Scf-2026 | Scleropages formosus | 38.46 | 6e-96 | 314 |
| LLPS-Leo-1029 | Lepisosteus oculatus | 38.46 | 1e-93 | 308 |
| LLPS-Fia-2096 | Ficedula albicollis | 38.46 | 2e-91 | 302 |
| LLPS-Meg-0509 | Meleagris gallopavo | 38.43 | 3e-92 | 304 |
| LLPS-Ori-1721 | Oryza indica | 38.42 | 2e-75 | 258 |
| LLPS-Anc-2178 | Anolis carolinensis | 38.38 | 9e-97 | 317 |
| LLPS-Sac-1128 | Saccharomyces cerevisiae | 38.28 | 2e-91 | 304 |
| LLPS-Hea-0048 | Helianthus annuus | 38.18 | 3e-80 | 269 |
| LLPS-Dio-2357 | Dipodomys ordii | 38.1 | 7e-87 | 289 |
| LLPS-Orbr-1842 | Oryza brachyantha | 37.92 | 1e-74 | 256 |
| LLPS-Php-2179 | Physcomitrella patens | 37.72 | 9e-85 | 283 |
| LLPS-Tag-1469 | Taeniopygia guttata | 37.68 | 4e-94 | 310 |
| LLPS-Sei-0293 | Setaria italica | 37.59 | 2e-76 | 261 |
| LLPS-Anp-1931 | Anas platyrhynchos | 37.39 | 1e-95 | 313 |
| LLPS-Gaga-1450 | Gallus gallus | 37.34 | 8e-96 | 314 |
| LLPS-Pot-1788 | Populus trichocarpa | 37.32 | 1e-79 | 269 |
| LLPS-Hov-1140 | Hordeum vulgare | 37.3 | 1e-81 | 275 |
| LLPS-Glm-2197 | Glycine max | 37.21 | 2e-79 | 269 |
| LLPS-Xet-0103 | Xenopus tropicalis | 37.16 | 3e-96 | 315 |
| LLPS-Fud-1811 | Fukomys damarensis | 37.1 | 1e-89 | 298 |
| LLPS-Ict-1757 | Ictidomys tridecemlineatus | 37.03 | 4e-89 | 296 |
| LLPS-Prp-0644 | Prunus persica | 37.03 | 1e-78 | 266 |
| LLPS-Pes-2100 | Pelodiscus sinensis | 37.03 | 4e-86 | 288 |
| LLPS-Lep-1595 | Leersia perrieri | 37.0 | 8e-71 | 245 |
| LLPS-Aim-1128 | Ailuropoda melanoleuca | 36.82 | 5e-90 | 299 |
| LLPS-Mod-2475 | Monodelphis domestica | 36.76 | 3e-90 | 299 |
| LLPS-Tra-2438 | Triticum aestivum | 36.75 | 4e-80 | 270 |
| LLPS-Brd-0607 | Brachypodium distachyon | 36.7 | 3e-77 | 263 |
| LLPS-Caf-1937 | Canis familiaris | 36.67 | 2e-91 | 303 |
| LLPS-Hos-1098 | Homo sapiens | 36.67 | 5e-93 | 306 |
| LLPS-Met-1084 | Medicago truncatula | 36.66 | 2e-79 | 269 |
| LLPS-Mal-2407 | Mandrillus leucophaeus | 36.62 | 4e-89 | 296 |
| LLPS-Phv-0223 | Phaseolus vulgaris | 36.61 | 3e-81 | 274 |
| LLPS-Caj-1871 | Callithrix jacchus | 36.6 | 1e-89 | 298 |
| LLPS-Maf-1188 | Macaca fascicularis | 36.6 | 1e-88 | 295 |
| LLPS-Mam-0650 | Macaca mulatta | 36.6 | 9e-89 | 295 |
| LLPS-Loa-1647 | Loxodonta africana | 36.6 | 2e-89 | 297 |
| LLPS-Mup-1383 | Mustela putorius furo | 36.58 | 5e-90 | 299 |
| LLPS-Sob-1491 | Sorghum bicolor | 36.53 | 1e-73 | 253 |
| LLPS-Paa-2669 | Papio anubis | 36.52 | 1e-89 | 298 |
| LLPS-Chs-2297 | Chlorocebus sabaeus | 36.46 | 2e-90 | 300 |
| LLPS-Urm-0486 | Ursus maritimus | 36.46 | 9e-91 | 301 |
| LLPS-Sem-1001 | Selaginella moellendorffii | 36.41 | 6e-71 | 246 |
| LLPS-Gog-1431 | Gorilla gorilla | 36.38 | 1e-88 | 295 |
| LLPS-Pap-3474 | Pan paniscus | 36.38 | 8e-89 | 296 |
| LLPS-Pat-0227 | Pan troglodytes | 36.38 | 1e-88 | 295 |
| LLPS-Man-1256 | Macaca nemestrina | 36.38 | 2e-88 | 294 |
| LLPS-Cas-0128 | Carlito syrichta | 36.36 | 1e-89 | 298 |
| LLPS-Rhb-0761 | Rhinopithecus bieti | 36.25 | 5e-91 | 301 |
| LLPS-Fec-1285 | Felis catus | 36.25 | 7e-90 | 299 |
| LLPS-Asg-1281 | Ashbya gossypii | 36.2 | 4e-98 | 322 |
| LLPS-Aon-1320 | Aotus nancymaae | 36.17 | 2e-88 | 295 |
| LLPS-Orc-0232 | Oryctolagus cuniculus | 36.15 | 3e-88 | 294 |
| LLPS-Gor-1840 | Gossypium raimondii | 36.11 | 9e-79 | 268 |
| LLPS-Zem-1962 | Zea mays | 36.08 | 3e-74 | 255 |
| LLPS-Viv-1630 | Vitis vinifera | 36.01 | 2e-80 | 273 |
| LLPS-Chr-1218 | Chlamydomonas reinhardtii | 35.94 | 1e-59 | 217 |
| LLPS-Crn-0711 | Cryptococcus neoformans | 35.8 | 6e-93 | 308 |
| LLPS-Nol-4023 | Nomascus leucogenys | 35.76 | 2e-84 | 284 |
| LLPS-Coc-0757 | Corchorus capsularis | 35.65 | 1e-71 | 255 |
| LLPS-Sol-1593 | Solanum lycopersicum | 35.59 | 1e-77 | 264 |
| LLPS-Cea-0546 | Cercocebus atys | 35.51 | 2e-84 | 284 |
| LLPS-Osl-0862 | Ostreococcus lucimarinus | 35.45 | 2e-74 | 256 |
| LLPS-Arl-0622 | Arabidopsis lyrata | 35.36 | 5e-71 | 246 |
| LLPS-Art-0842 | Arabidopsis thaliana | 35.36 | 3e-72 | 249 |
| LLPS-Mua-0159 | Musa acuminata | 35.33 | 6e-80 | 270 |
| LLPS-Gas-0192 | Galdieria sulphuraria | 35.25 | 3e-62 | 223 |
| LLPS-Amt-0662 | Amborella trichopoda | 35.14 | 4e-77 | 262 |
| LLPS-Mae-1567 | Manihot esculenta | 35.03 | 3e-25 | 109 |
| LLPS-Sus-1732 | Sus scrofa | 34.9 | 3e-91 | 302 |
| LLPS-Ran-4017 | Rattus norvegicus | 34.81 | 4e-93 | 307 |
| LLPS-Myl-0740 | Myotis lucifugus | 34.81 | 9e-90 | 298 |
| LLPS-Vir-0445 | Vigna radiata | 34.78 | 6e-60 | 218 |
| LLPS-Orp-0387 | Oryza punctata | 34.75 | 1e-55 | 203 |
| LLPS-Drm-0549 | Drosophila melanogaster | 34.54 | 3e-67 | 239 |
| LLPS-Eqc-2604 | Equus caballus | 34.52 | 1e-88 | 296 |
| LLPS-Cae-2015 | Caenorhabditis elegans | 34.43 | 9e-82 | 276 |
| LLPS-Ere-0360 | Erinaceus europaeus | 34.26 | 1e-91 | 304 |
| LLPS-Mum-3758 | Mus musculus | 34.25 | 1e-91 | 303 |
| LLPS-Mea-0574 | Mesocricetus auratus | 34.25 | 9e-92 | 303 |
| LLPS-Dac-2298 | Daucus carota | 34.15 | 5e-42 | 159 |
| LLPS-Otg-2228 | Otolemur garnettii | 34.12 | 2e-91 | 302 |
| LLPS-Ova-1414 | Ovis aries | 34.05 | 2e-88 | 295 |
| LLPS-Bot-0575 | Bos taurus | 34.0 | 2e-87 | 292 |
| LLPS-Brn-2169 | Brassica napus | 33.95 | 2e-72 | 250 |
| LLPS-Orb-0661 | Oryza barthii | 33.89 | 1e-54 | 200 |
| LLPS-Orm-0391 | Oryza meridionalis | 33.86 | 5e-55 | 201 |
| LLPS-Orr-0132 | Oryza rufipogon | 33.86 | 9e-55 | 200 |
| LLPS-Bro-1206 | Brassica oleracea | 33.72 | 2e-72 | 251 |
| LLPS-Brr-1916 | Brassica rapa | 33.72 | 3e-72 | 249 |
| LLPS-Orgl-1272 | Oryza glumaepatula | 33.49 | 3e-55 | 202 |
| LLPS-Orni-0922 | Oryza nivara | 33.26 | 8e-55 | 201 |
| LLPS-Thc-0940 | Theobroma cacao | 33.12 | 2e-69 | 243 |
| LLPS-Cis-1391 | Ciona savignyi | 33.03 | 1e-69 | 243 |
| LLPS-Cus-1816 | Cucumis sativus | 32.86 | 4e-76 | 260 |
| LLPS-Cii-0146 | Ciona intestinalis | 32.77 | 4e-73 | 253 |
| LLPS-Tru-0970 | Triticum urartu | 29.34 | 1e-41 | 162 |
| LLPS-Ors-0106 | Oryza sativa | 28.37 | 7e-20 | 98.6 |
| LLPS-Cym-0683 | Cyanidioschyzon merolae | 28.1 | 2e-40 | 160 |
| LLPS-Sot-0194 | Solanum tuberosum | 24.41 | 6e-21 | 101 |
| LLPS-Orl-0631 | Oryzias latipes | 24.08 | 3e-20 | 99.8 |