DrLLPS - Data resource of LLPS

LLPS-Trr-1387
TRIREDRAFT_33207

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Gamma-glutamylcyclotransferase
Gene Name:	TRIREDRAFT_33207
Ensembl Gene:	TRIREDRAFT_33207
Ensembl Protein:	EGR50718
Organism:	Trichoderma reesei
Taxa ID:	431241
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0324	P32656	Client	Stress granule	40.29	7e-38	136

▼ FUNCTION

Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	EGR50718	EGR50718
UniProt		G0RDI6, G0RDI6_HYPJQ
GeneBank	GL985059	EGR50718.1
RefSeq	XM_006963027.1	XP_006963089.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 YRSLIWKPPP HFDRRIPGWV TGYVRRFWQD HRGTPEAPGR VVTLIERSHW EQLTDHHDSA 60 61 PDKVWGVAYR IHPDHVAEVK EYLDIREING YSIHYTPFHP ADGSPPIQTL VYIGTPDNEQ 120 121 FVGPQDPQQL AEHILRSRGP SGLNKDYLFG LEAALAELCP ESEDVHVSDL ARRVR 175
Nucleotide CDS Sequence (FASTA)
1 TATAGGAGCC TCATATGGAA GCCCCCGCCG CATTTCGACA GAAGAATCCC TGGCTGGGTG 60 61 ACGGGCTATG TTCGGCGCTT CTGGCAGGAT CATCGGGGAA CGCCAGAAGC CCCCGGGCGG 120 121 GTGGTCACGC TCATTGAACG CTCCCACTGG GAACAGCTCA CGGATCACCA TGACTCTGCC 180 181 CCTGACAAGG TATGGGGCGT AGCTTATCGG ATTCACCCCG ACCATGTCGC GGAGGTCAAG 240 241 GAGTATCTCG ATATCCGCGA GATCAACGGC TACTCCATCC ACTACACGCC TTTCCACCCC 300 301 GCCGATGGCT CCCCGCCTAT TCAGACACTC GTCTACATCG GCACGCCCGA TAACGAGCAG 360 361 TTTGTCGGCC CCCAAGATCC TCAGCAGCTC GCCGAGCACA TCTTGCGTAG TCGTGGACCC 420 421 AGTGGGCTGA ACAAGGATTA TCTCTTTGGC CTGGAGGCGG CCTTGGCTGA GCTGTGCCCA 480 481 GAGAGCGAAG ATGTCCACGT TAGCGATCTC GCACGCCGCG TGAGG 525

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0456	Lyase
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0003839	Molecular Function	Gamma-glutamylcyclotransferase activity
GO:0061928	Molecular Function	Glutathione specific gamma-glutamylcyclotransferase activity
GO:0006751	Biological Process	Glutathione catabolic process

▼ KEGG

tre:TRIREDRAFT_33207

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Beb-1480	Beauveria bassiana	93.1	2e-11	61.2
LLPS-Trv-1622	Trichoderma virens	86.29	2e-103	303
LLPS-Cog-0723	Colletotrichum gloeosporioides	81.63	1e-84	254
LLPS-Mao-0817	Magnaporthe oryzae	79.21	2e-96	286
LLPS-Fuv-0371	Fusarium verticillioides	78.34	6e-84	253
LLPS-Gag-0501	Gaeumannomyces graminis	78.21	1e-93	280
LLPS-Cogr-0904	Colletotrichum graminicola	77.71	3e-82	249
LLPS-Coo-1626	Colletotrichum orbiculare	77.71	3e-83	251
LLPS-Fus-0802	Fusarium solani	76.1	8e-79	240
LLPS-Nec-0333	Neurospora crassa	76.06	8e-95	283
LLPS-Fuo-1580	Fusarium oxysporum	75.76	6e-85	256
LLPS-Map-0672	Magnaporthe poae	71.5	4e-85	259
LLPS-Zyt-1372	Zymoseptoria tritici	64.8	2e-77	237
LLPS-Ved-0195	Verticillium dahliae	63.89	1e-70	220
LLPS-Scs-0847	Sclerotinia sclerotiorum	61.05	1e-62	199
LLPS-Dos-1464	Dothistroma septosporum	61.0	4e-77	236
LLPS-Blg-0051	Blumeria graminis	60.68	3e-43	147
LLPS-Yal-1241	Yarrowia lipolytica	57.87	2e-67	212
LLPS-Phn-1520	Phaeosphaeria nodorum	57.49	1e-72	226
LLPS-Tum-1545	Tuber melanosporum	55.83	9e-51	168
LLPS-Asn-0617	Aspergillus nidulans	53.03	1e-61	198
LLPS-Asni-1587	Aspergillus niger	51.61	2e-52	174
LLPS-Aso-0968	Aspergillus oryzae	51.55	7e-43	148
LLPS-Lem-1045	Leptosphaeria maculans	49.74	6e-50	167
LLPS-Asf-1552	Aspergillus flavus	49.22	1e-29	113
LLPS-Asc-1645	Aspergillus clavatus	48.81	7e-42	145
LLPS-Scj-1532	Schizosaccharomyces japonicus	48.07	1e-48	163
LLPS-Icp-0121	Ictalurus punctatus	47.22	1e-40	141
LLPS-Dar-4182	Danio rerio	46.96	1e-40	141
LLPS-Scp-0551	Schizosaccharomyces pombe	46.7	4e-45	154
LLPS-Scc-1598	Schizosaccharomyces cryophilus	46.7	4e-43	148
LLPS-Mel-0184	Melampsora laricipopulina	46.11	2e-41	144
LLPS-Asm-0566	Astyanax mexicanus	45.81	1e-41	144
LLPS-Put-0455	Puccinia triticina	45.31	9e-09	58.2
LLPS-Xet-3827	Xenopus tropicalis	45.25	6e-39	137
LLPS-Pug-0256	Puccinia graminis	44.75	5e-40	140
LLPS-Cis-0175	Ciona savignyi	44.44	6e-38	134
LLPS-Pytr-1506	Pyrenophora triticirepentis	44.26	1e-39	139
LLPS-Drm-1355	Drosophila melanogaster	44.26	4e-34	128
LLPS-Ten-3112	Tetraodon nigroviridis	44.2	2e-34	125
LLPS-Tar-0676	Takifugu rubripes	44.2	7e-38	135
LLPS-Tag-1026	Taeniopygia guttata	44.13	2e-37	133
LLPS-Aon-0511	Aotus nancymaae	44.13	4e-38	135
LLPS-Cii-1386	Ciona intestinalis	44.13	3e-40	140
LLPS-Asfu-1613	Aspergillus fumigatus	44.12	1e-54	181
LLPS-Mod-1434	Monodelphis domestica	43.86	6e-36	130
LLPS-Aim-3048	Ailuropoda melanoleuca	43.68	2e-37	133
LLPS-Orn-4070	Oreochromis niloticus	43.65	3e-38	135
LLPS-Nol-0629	Nomascus leucogenys	43.58	6e-38	134
LLPS-Anc-0424	Anolis carolinensis	43.58	7e-36	132
LLPS-Gaga-2072	Gallus gallus	43.58	1e-38	136
LLPS-Mam-2059	Macaca mulatta	43.58	2e-37	133
LLPS-Caf-2942	Canis familiaris	43.58	2e-38	136
LLPS-Poa-3538	Pongo abelii	43.58	8e-38	134
LLPS-Rhb-2009	Rhinopithecus bieti	43.58	1e-37	134
LLPS-Pes-0492	Pelodiscus sinensis	43.58	3e-39	138
LLPS-Man-3659	Macaca nemestrina	43.58	2e-37	133
LLPS-Hos-4779	Homo sapiens	43.58	1e-37	134
LLPS-Pap-0470	Pan paniscus	43.58	1e-37	134
LLPS-Pat-2696	Pan troglodytes	43.58	1e-37	134
LLPS-Mal-2486	Mandrillus leucophaeus	43.58	1e-37	134
LLPS-Ova-4244	Ovis aries	43.58	8e-39	137
LLPS-Caj-3340	Callithrix jacchus	43.58	4e-38	135
LLPS-Gog-4288	Gorilla gorilla	43.58	1e-37	134
LLPS-Leo-2763	Lepisosteus oculatus	43.58	3e-39	138
LLPS-Cea-4217	Cercocebus atys	43.58	1e-37	134
LLPS-Maf-3874	Macaca fascicularis	43.58	2e-37	133
LLPS-Chs-4581	Chlorocebus sabaeus	43.58	1e-37	134
LLPS-Sol-2429	Solanum lycopersicum	43.24	1e-34	126
LLPS-Anp-2061	Anas platyrhynchos	43.23	2e-31	117
LLPS-Myl-1138	Myotis lucifugus	43.09	2e-36	130
LLPS-Scf-3225	Scleropages formosus	43.09	1e-35	129
LLPS-Urm-3930	Ursus maritimus	43.02	7e-39	137
LLPS-Mup-3589	Mustela putorius furo	43.02	2e-38	135
LLPS-Sah-3721	Sarcophilus harrisii	43.02	9e-38	134
LLPS-Pof-3207	Poecilia formosa	42.78	5e-35	127
LLPS-Fud-2425	Fukomys damarensis	42.78	4e-36	129
LLPS-Lac-1047	Latimeria chalumnae	42.54	7e-39	137
LLPS-Nef-1463	Neosartorya fischeri	42.53	4e-45	156
LLPS-Loa-3664	Loxodonta africana	42.46	1e-37	134
LLPS-Fec-0584	Felis catus	42.46	3e-38	135
LLPS-Ere-0251	Erinaceus europaeus	42.46	1e-37	134
LLPS-Sus-3902	Sus scrofa	42.46	8e-38	134
LLPS-Xim-2515	Xiphophorus maculatus	42.22	8e-35	126
LLPS-Gas-1263	Galdieria sulphuraria	42.21	2e-32	121
LLPS-Nia-1411	Nicotiana attenuata	42.16	6e-35	127
LLPS-Ict-0354	Ictidomys tridecemlineatus	41.9	9e-37	131
LLPS-Cas-2903	Carlito syrichta	41.9	1e-37	134
LLPS-Eqc-4316	Equus caballus	41.9	1e-37	134
LLPS-Orc-2357	Oryctolagus cuniculus	41.9	3e-36	132
LLPS-Otg-0545	Otolemur garnettii	41.9	1e-37	134
LLPS-Ran-2792	Rattus norvegicus	41.9	7e-38	134
LLPS-Dio-3476	Dipodomys ordii	41.9	7e-37	132
LLPS-Mum-3508	Mus musculus	41.9	9e-38	134
LLPS-Mea-1715	Mesocricetus auratus	41.9	3e-37	132
LLPS-Gaa-2843	Gasterosteus aculeatus	41.67	2e-34	125
LLPS-Sot-2092	Solanum tuberosum	41.42	1e-28	110
LLPS-Cap-3697	Cavia porcellus	41.34	1e-35	129
LLPS-Scm-0522	Scophthalmus maximus	41.11	4e-33	123
LLPS-Ast-1415	Aspergillus terreus	41.0	2e-32	122
LLPS-Asg-0650	Ashbya gossypii	40.78	1e-33	124
LLPS-Crn-1412	Cryptococcus neoformans	40.58	2e-36	132
LLPS-Prp-0706	Prunus persica	40.54	5e-31	118
LLPS-Art-2994	Arabidopsis thaliana	40.54	1e-28	110
LLPS-Glm-1604	Glycine max	40.54	4e-30	114
LLPS-Bro-1708	Brassica oleracea	40.32	1e-28	110
LLPS-Coc-0560	Corchorus capsularis	40.32	8e-30	114
LLPS-Sac-0324	Saccharomyces cerevisiae	40.29	5e-38	136
LLPS-Arl-2058	Arabidopsis lyrata	40.0	2e-27	107
LLPS-Via-1287	Vigna angularis	40.0	7e-31	116
LLPS-Cym-1147	Cyanidioschyzon merolae	39.89	2e-26	105
LLPS-Kop-0599	Komagataella pastoris	39.8	9e-35	128
LLPS-Brr-1014	Brassica rapa	39.78	2e-27	107
LLPS-Abg-1612	Absidia glauca	39.78	2e-35	129
LLPS-Brn-1421	Brassica napus	39.78	1e-27	108
LLPS-Php-2123	Physcomitrella patens	39.57	2e-25	102
LLPS-Chr-0454	Chlamydomonas reinhardtii	39.51	2e-22	95.9
LLPS-Amt-2246	Amborella trichopoda	39.46	2e-29	113
LLPS-Cus-0763	Cucumis sativus	39.25	1e-30	116
LLPS-Brd-1898	Brachypodium distachyon	39.04	7e-26	103
LLPS-Mae-2676	Manihot esculenta	38.92	2e-29	112
LLPS-Phv-2237	Phaseolus vulgaris	38.92	3e-29	112
LLPS-Sem-1534	Selaginella moellendorffii	38.82	2e-25	101
LLPS-Miv-1435	Microbotryum violaceum	38.76	3e-30	115
LLPS-Gor-1247	Gossypium raimondii	38.71	2e-27	108
LLPS-Sob-0025	Sorghum bicolor	38.38	6e-26	103
LLPS-Thc-1736	Theobroma cacao	38.38	7e-27	105
LLPS-Dac-1858	Daucus carota	38.38	5e-29	111
LLPS-Org-0939	Oryza glaberrima	38.17	2e-24	99.4
LLPS-Ors-1462	Oryza sativa	38.17	3e-24	99.4
LLPS-Sei-1929	Setaria italica	38.17	6e-25	101
LLPS-Tra-0465	Triticum aestivum	38.17	7e-26	103
LLPS-Orgl-1373	Oryza glumaepatula	38.17	2e-24	99.4
LLPS-Orni-2316	Oryza nivara	38.17	2e-24	99.4
LLPS-Hea-0658	Helianthus annuus	38.17	1e-28	110
LLPS-Orb-1117	Oryza barthii	38.17	2e-24	99.4
LLPS-Ori-1265	Oryza indica	38.17	2e-24	99.4
LLPS-Paa-4191	Papio anubis	38.12	1e-29	115
LLPS-Viv-2493	Vitis vinifera	37.84	1e-27	108
LLPS-Lep-0991	Leersia perrieri	37.63	4e-25	102
LLPS-Bot-0457	Bos taurus	37.43	2e-31	117
LLPS-Orr-1295	Oryza rufipogon	37.1	3e-24	99.8
LLPS-Orp-2095	Oryza punctata	37.1	5e-24	99.4
LLPS-Mua-2468	Musa acuminata	36.81	1e-21	92.0
LLPS-Met-2037	Medicago truncatula	36.76	2e-24	99.8
LLPS-Pot-0703	Populus trichocarpa	36.62	1e-27	110
LLPS-Orm-0479	Oryza meridionalis	36.56	1e-23	98.2
LLPS-Orl-3074	Oryzias latipes	36.11	2e-27	107
LLPS-Orbr-2120	Oryza brachyantha	36.02	1e-24	101
LLPS-Tut-1044	Tursiops truncatus	35.23	4e-27	107
LLPS-Osl-0717	Ostreococcus lucimarinus	35.16	2e-19	86.3
LLPS-Tru-1001	Triticum urartu	34.95	7e-22	93.2
LLPS-Vir-0820	Vigna radiata	34.41	5e-19	85.5
LLPS-Hov-0469	Hordeum vulgare	34.41	1e-21	92.8
LLPS-Zem-2283	Zea mays	32.33	1e-20	90.5
LLPS-Cae-1252	Caenorhabditis elegans	30.98	1e-18	84.3

LLPS-Trr-1387TRIREDRAFT_33207

Protein Sequence

Nucleotide Sequence

LLPS-Trr-1387
TRIREDRAFT_33207