DrLLPS - Data resource of LLPS

LLPS-Php-2123
PHYPA_011556

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Gamma-glutamylcyclotransferase
Gene Name:	PHYPA_011556
Ensembl Gene:	Pp3c8_14920
Ensembl Protein:	Pp3c8_14920V3.2
Organism:	Physcomitrella patens
Taxa ID:	3218
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0324	P32656	Client	Stress granule	32.60	3e-22	95.9

▼ FUNCTION

Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and plays a significant role in glutathione (GSH) homeostasis.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	Pp3c8_14920V3.2	Pp3c8_14920V3.2
Ensembl	Pp3c8_14920V3.3	Pp3c8_14920V3.3
Ensembl	Pp3c8_14920V3.4	Pp3c8_14920V3.4
Ensembl	Pp3c8_14920V3.1	Pp3c8_14920V3.1
UniProt		A0A2K1K7A3, A0A2K1K7A3_PHYPA
GeneBank	ABEU02000008	PNR49660.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MVLWVFGYGS LLWKAGFDYD ERLVGYIKGY RRVFYQANTD HRGTAAYPGR VVTLEAIEGA 60 61 ITWGAAYRVS GDDKEALVLS YLDLREQEYD QKEHVNFYTA DCLETPTVCN VLVYIGSSDK 120 121 FKNRFWAGPA PLDEMAKQIA RAVGPSGPNY EYLFRLEECL HELDCVDADI CELAEAVRKQ 180 181 MNSSKGVNVT SERPEINLTT EVYSCLENNH MIPATEHR 218
Nucleotide CDS Sequence (FASTA)
1 ATGGTACTTT GGGTGTTTGG TTACGGTTCA CTTTTATGGA AAGCAGGTTT CGATTACGAT 60 61 GAGAGGTTGG TGGGCTACAT TAAGGGCTAT CGCAGAGTGT TTTATCAAGC CAACACAGAT 120 121 CACCGAGGCA CAGCTGCATA TCCTGGACGT GTTGTGACGC TAGAGGCAAT CGAGGGGGCA 180 181 ATCACATGGG GTGCTGCATA CCGAGTATCC GGTGATGATA AGGAGGCACT TGTTCTATCT 240 241 TATTTGGATC TCAGAGAACA AGAATATGAT CAAAAAGAGC ATGTCAACTT TTATACGGCG 300 301 GATTGTTTAG AGACACCGAC CGTCTGCAAT GTTCTTGTGT ATATTGGTTC TTCTGACAAG 360 361 TTTAAGAATA GGTTCTGGGC GGGACCTGCA CCCTTGGACG AGATGGCAAA ACAAATTGCT 420 421 CGAGCAGTGG GTCCATCTGG ACCGAATTAT GAATACTTAT TTCGTCTGGA AGAGTGTCTG 480 481 CATGAACTTG ATTGTGTGGA TGCGGACATT TGTGAGCTTG CTGAGGCTGT CCGAAAGCAA 540 541 ATGAATTCAA GTAAAGGAGT CAATGTCACA TCTGAGAGGC CTGAAATAAA TTTAACAACT 600 601 GAAGTTTATT CATGTTTAGA AAATAACCAT ATGATACCTG CAACTGAGCA TAGGTAG 657

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0003839	Molecular Function	Gamma-glutamylcyclotransferase activity
GO:0006751	Biological Process	Glutathione catabolic process

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Sem-1534	Selaginella moellendorffii	68.71	1e-77	238
LLPS-Sot-2092	Solanum tuberosum	57.67	2e-65	207
LLPS-Mae-2676	Manihot esculenta	56.67	4e-73	226
LLPS-Amt-2246	Amborella trichopoda	56.59	4e-71	221
LLPS-Prp-0706	Prunus persica	56.35	4e-73	229
LLPS-Phv-2237	Phaseolus vulgaris	55.31	1e-68	215
LLPS-Viv-2493	Vitis vinifera	55.26	1e-71	223
LLPS-Dac-1858	Daucus carota	55.25	2e-70	219
LLPS-Sol-2429	Solanum lycopersicum	54.95	2e-71	223
LLPS-Glm-1604	Glycine max	54.75	1e-69	218
LLPS-Sob-0025	Sorghum bicolor	53.67	1e-65	207
LLPS-Coc-0560	Corchorus capsularis	53.23	1e-70	220
LLPS-Org-0939	Oryza glaberrima	53.07	2e-67	212
LLPS-Orni-2316	Oryza nivara	53.07	2e-67	212
LLPS-Ori-1265	Oryza indica	53.07	2e-67	212
LLPS-Orb-1117	Oryza barthii	53.07	2e-67	212
LLPS-Brd-1898	Brachypodium distachyon	53.07	4e-67	211
LLPS-Orgl-1373	Oryza glumaepatula	53.07	2e-67	212
LLPS-Nia-1411	Nicotiana attenuata	52.75	4e-69	216
LLPS-Ors-1462	Oryza sativa	52.51	1e-66	210
LLPS-Hea-0658	Helianthus annuus	52.46	3e-64	204
LLPS-Gor-1247	Gossypium raimondii	52.43	6e-69	218
LLPS-Thc-1736	Theobroma cacao	52.43	7e-69	216
LLPS-Met-2037	Medicago truncatula	51.89	2e-67	212
LLPS-Beb-1480	Beauveria bassiana	51.43	5e-06	47.0
LLPS-Tra-0465	Triticum aestivum	51.37	2e-66	209
LLPS-Via-1287	Vigna angularis	51.35	7e-68	213
LLPS-Vir-0820	Vigna radiata	51.1	3e-58	190
LLPS-Mua-2468	Musa acuminata	50.82	2e-62	199
LLPS-Cus-0763	Cucumis sativus	50.8	6e-65	206
LLPS-Brr-1014	Brassica rapa	50.27	9e-65	206
LLPS-Bro-1708	Brassica oleracea	50.27	6e-65	206
LLPS-Arl-2058	Arabidopsis lyrata	49.74	3e-66	209
LLPS-Brn-1421	Brassica napus	49.73	2e-63	202
LLPS-Caf-2942	Canis familiaris	49.4	1e-43	151
LLPS-Pot-0703	Populus trichocarpa	49.28	3e-66	212
LLPS-Art-2994	Arabidopsis thaliana	49.21	3e-65	207
LLPS-Tru-1001	Triticum urartu	49.21	3e-57	187
LLPS-Leo-2763	Lepisosteus oculatus	49.11	8e-40	141
LLPS-Aim-3048	Ailuropoda melanoleuca	49.1	4e-43	150
LLPS-Orp-2095	Oryza punctata	48.72	5e-58	189
LLPS-Orm-0479	Oryza meridionalis	48.72	7e-58	189
LLPS-Mod-1434	Monodelphis domestica	48.52	5e-42	147
LLPS-Orr-1295	Oryza rufipogon	48.47	5e-58	189
LLPS-Sei-1929	Setaria italica	48.28	2e-60	195
LLPS-Orbr-2120	Oryza brachyantha	48.21	4e-57	187
LLPS-Lep-0991	Leersia perrieri	48.21	1e-57	188
LLPS-Icp-0121	Ictalurus punctatus	47.62	2e-40	142
LLPS-Dar-4182	Danio rerio	47.34	5e-40	141
LLPS-Scf-3225	Scleropages formosus	47.02	8e-38	136
LLPS-Loa-3664	Loxodonta africana	46.96	5e-43	149
LLPS-Hov-0469	Hordeum vulgare	46.83	1e-55	182
LLPS-Xet-3827	Xenopus tropicalis	46.81	7e-43	149
LLPS-Anc-0424	Anolis carolinensis	46.77	3e-41	147
LLPS-Chr-0454	Chlamydomonas reinhardtii	46.67	6e-46	161
LLPS-Pes-0492	Pelodiscus sinensis	46.56	5e-44	152
LLPS-Sus-3902	Sus scrofa	46.49	1e-44	153
LLPS-Asm-0566	Astyanax mexicanus	46.24	9e-41	143
LLPS-Lac-1047	Latimeria chalumnae	46.15	9e-39	139
LLPS-Gaga-2072	Gallus gallus	46.03	1e-42	148
LLPS-Otg-0545	Otolemur garnettii	45.86	2e-42	147
LLPS-Mum-3508	Mus musculus	45.86	7e-43	149
LLPS-Mea-1715	Mesocricetus auratus	45.86	8e-43	149
LLPS-Ran-2792	Rattus norvegicus	45.86	5e-43	149
LLPS-Dio-3476	Dipodomys ordii	45.86	1e-41	145
LLPS-Ten-3112	Tetraodon nigroviridis	45.83	8e-37	133
LLPS-Orc-2357	Oryctolagus cuniculus	45.74	2e-44	155
LLPS-Cas-2903	Carlito syrichta	45.74	1e-44	153
LLPS-Tag-1026	Taeniopygia guttata	45.5	1e-42	148
LLPS-Cap-3697	Cavia porcellus	45.3	1e-40	143
LLPS-Fud-2425	Fukomys damarensis	45.3	5e-41	144
LLPS-Fec-0584	Felis catus	45.21	2e-44	153
LLPS-Urm-3930	Ursus maritimus	45.21	2e-44	153
LLPS-Mup-3589	Mustela putorius furo	45.21	4e-44	152
LLPS-Ere-0251	Erinaceus europaeus	45.21	4e-43	149
LLPS-Ova-4244	Ovis aries	44.85	9e-45	154
LLPS-Pof-3207	Poecilia formosa	44.74	2e-39	140
LLPS-Myl-1138	Myotis lucifugus	44.74	6e-42	146
LLPS-Sah-3721	Sarcophilus harrisii	44.68	2e-42	148
LLPS-Xim-2515	Xiphophorus maculatus	44.68	9e-40	141
LLPS-Orn-4070	Oreochromis niloticus	44.62	2e-41	145
LLPS-Rhb-2009	Rhinopithecus bieti	44.21	3e-42	147
LLPS-Man-3659	Macaca nemestrina	44.15	1e-41	145
LLPS-Hos-4779	Homo sapiens	44.15	8e-42	146
LLPS-Pap-0470	Pan paniscus	44.15	8e-42	146
LLPS-Pat-2696	Pan troglodytes	44.15	8e-42	146
LLPS-Nol-0629	Nomascus leucogenys	44.15	4e-42	147
LLPS-Ict-0354	Ictidomys tridecemlineatus	44.15	5e-42	147
LLPS-Mam-2059	Macaca mulatta	44.15	1e-41	145
LLPS-Eqc-4316	Equus caballus	44.15	5e-43	149
LLPS-Poa-3538	Pongo abelii	44.15	6e-42	146
LLPS-Caj-3340	Callithrix jacchus	44.15	2e-42	147
LLPS-Gog-4288	Gorilla gorilla	44.15	8e-42	146
LLPS-Aon-0511	Aotus nancymaae	44.15	4e-41	144
LLPS-Cea-4217	Cercocebus atys	44.15	8e-42	146
LLPS-Chs-4581	Chlorocebus sabaeus	44.15	8e-42	146
LLPS-Maf-3874	Macaca fascicularis	44.15	1e-41	145
LLPS-Mal-2486	Mandrillus leucophaeus	44.15	8e-42	146
LLPS-Cii-1386	Ciona intestinalis	43.82	2e-37	135
LLPS-Orl-3074	Oryzias latipes	43.79	3e-30	116
LLPS-Anp-2061	Anas platyrhynchos	43.75	1e-27	108
LLPS-Osl-0717	Ostreococcus lucimarinus	43.58	3e-37	134
LLPS-Cis-0175	Ciona savignyi	43.33	6e-37	133
LLPS-Gaa-2843	Gasterosteus aculeatus	43.24	8e-41	144
LLPS-Paa-4191	Papio anubis	42.33	4e-31	120
LLPS-Tut-1044	Tursiops truncatus	42.33	1e-31	120
LLPS-Bot-0457	Bos taurus	42.27	4e-37	134
LLPS-Scm-0522	Scophthalmus maximus	42.25	1e-35	131
LLPS-Tar-0676	Takifugu rubripes	41.62	1e-36	133
LLPS-Cym-1147	Cyanidioschyzon merolae	41.53	1e-31	121
LLPS-Abg-1612	Absidia glauca	40.33	1e-29	114
LLPS-Trr-1387	Trichoderma reesei	39.57	3e-25	102
LLPS-Miv-1435	Microbotryum violaceum	39.31	7e-26	105
LLPS-Gag-0501	Gaeumannomyces graminis	39.29	2e-34	129
LLPS-Zem-2283	Zea mays	38.98	9e-51	171
LLPS-Drm-1355	Drosophila melanogaster	38.8	8e-29	115
LLPS-Fus-0802	Fusarium solani	38.73	9e-22	94.0
LLPS-Cog-0723	Colletotrichum gloeosporioides	38.61	3e-17	80.9
LLPS-Phn-1520	Phaeosphaeria nodorum	38.38	3e-26	107
LLPS-Fuv-0371	Fusarium verticillioides	38.12	5e-16	77.8
LLPS-Mel-0184	Melampsora laricipopulina	38.01	1e-28	112
LLPS-Asn-0617	Aspergillus nidulans	37.98	6e-28	112
LLPS-Scp-0551	Schizosaccharomyces pombe	37.88	8e-27	107
LLPS-Mao-0817	Magnaporthe oryzae	37.86	1e-30	118
LLPS-Gas-1263	Galdieria sulphuraria	37.82	7e-34	126
LLPS-Fuo-1580	Fusarium oxysporum	36.96	9e-17	79.7
LLPS-Zyt-1372	Zymoseptoria tritici	36.89	3e-26	106
LLPS-Cae-1252	Caenorhabditis elegans	36.69	5e-24	100
LLPS-Asf-1552	Aspergillus flavus	36.44	3e-06	49.7
LLPS-Nec-0333	Neurospora crassa	36.32	3e-31	120
LLPS-Cogr-0904	Colletotrichum graminicola	36.31	5e-17	80.9
LLPS-Yal-1241	Yarrowia lipolytica	35.98	1e-29	116
LLPS-Ved-0195	Verticillium dahliae	35.84	1e-13	71.2
LLPS-Coo-1626	Colletotrichum orbiculare	35.8	1e-16	79.7
LLPS-Dos-1464	Dothistroma septosporum	35.59	4e-28	111
LLPS-Asg-0650	Ashbya gossypii	35.45	1e-27	110
LLPS-Blg-0051	Blumeria graminis	35.38	5e-09	56.6
LLPS-Scs-0847	Sclerotinia sclerotiorum	35.06	3e-14	72.8
LLPS-Aso-0968	Aspergillus oryzae	35.03	6e-11	63.2
LLPS-Map-0672	Magnaporthe poae	34.69	8e-21	92.4
LLPS-Kop-0599	Komagataella pastoris	34.6	1e-20	91.7
LLPS-Scj-1532	Schizosaccharomyces japonicus	34.48	3e-22	95.9
LLPS-Pug-0256	Puccinia graminis	33.51	1e-21	93.6
LLPS-Trv-1622	Trichoderma virens	33.5	3e-19	87.4
LLPS-Crn-1412	Cryptococcus neoformans	33.49	1e-24	102
LLPS-Scc-1598	Schizosaccharomyces cryophilus	33.33	4e-22	94.7
LLPS-Asni-1587	Aspergillus niger	32.82	1e-17	83.2
LLPS-Sac-0324	Saccharomyces cerevisiae	32.6	3e-22	95.9
LLPS-Asc-1645	Aspergillus clavatus	32.57	4e-10	60.8
LLPS-Asfu-1613	Aspergillus fumigatus	31.71	8e-20	89.7
LLPS-Tum-1545	Tuber melanosporum	31.29	2e-12	67.4

LLPS-Php-2123PHYPA_011556

Protein Sequence

Nucleotide Sequence

LLPS-Php-2123
PHYPA_011556