LLPS-Thc-2353
TCM_005037
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pyruvate dehydrogenase E1 component subunit alpha |
| Gene Name: | TCM_005037 |
| Ensembl Gene: | TCM_005037 |
| Ensembl Protein: | EOX95585 |
| Organism: | Theobroma cacao |
| Taxa ID: | 3641 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | EOX95585 | EOX95585 |
| UniProt | A0A061DS84, A0A061DS84_THECC | |
| GeneBank | CM001879 | EOX95585.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MALSMCRYVW WLSLSFPLHQ FLPTLPARRL FPRPFPRCFR PPFFFLSPPS SLLYLSQSIF 60 61 HSLLHLPFSL LSSSPANTPH QKPKGSRKVE RDRTMSSAFS AGKFTTQPFP LNTSSPRSHD 120 121 KPFNIPSATS PFFGSSRKLR LNSSSKLNLH RRSGTVVAVS DVVKEKKSKF APNLLITKEE 180 181 GLVLYEDMVL GRAFEDMCAQ MYYRGKMFGF VHLYNGQEAV STGFIKHLKK EDSVVSTYRD 240 241 HVHALSKGVP ARAVMSELFG KTTGCCRGQG GSMHMFSSEH NLLGGFAFIG EGIPVATGAA 300 301 FTSKYKREVL KEADCDHVTL AFFGDGTCNN GQFFECLNMA ALWKLPIVFV VENNLWAIGM 360 361 SHLRATSDPQ IYKKGPAFGM PGIHVDGMDV LKVREVAKEA IGRARRGEGP TLVECETYRF 420 421 RGHSLADPDE LRDPAEKAHY AARDPITALK KYLIENSLAS EAELKAIDKK IDEVVEDSVE 480 481 FADESPLPSR SQLLENVFAD PKGFGIGPDG QYRCEDPKFT EGTAHV 526 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCCTTAT CAATGTGTCG TTATGTTTGG TGGCTCTCCC TTTCTTTTCC ACTTCATCAA 60 61 TTCCTCCCGA CGCTCCCTGC CAGGCGATTA TTCCCACGCC CTTTCCCTCG TTGCTTCCGC 120 121 CCCCCATTTT TCTTTCTTTC CCCCCCTTCC TCTCTTTTAT ATCTTTCCCA ATCTATCTTT 180 181 CATTCCCTCC TTCACCTCCC ATTTTCCCTG CTTTCCTCCT CCCCCGCTAA CACTCCCCAT 240 241 CAGAAACCAA AAGGAAGCCG AAAAGTAGAA AGGGATAGAA CAATGTCTAG CGCTTTCTCC 300 301 GCAGGCAAGT TCACCACCCA GCCTTTCCCT CTCAACACCA GTTCCCCCAG ATCTCACGAC 360 361 AAGCCCTTCA ATATCCCCAG CGCCACCTCA CCTTTCTTCG GATCCTCCCG CAAACTCCGC 420 421 CTTAATTCTT CTTCCAAATT GAATCTCCAC CGTCGATCGG GGACCGTCGT CGCCGTCTCC 480 481 GATGTCGTCA AGGAAAAGAA ATCCAAATTC GCCCCCAATC TGTTAATTAC TAAAGAAGAA 540 541 GGATTGGTAT TGTACGAAGA TATGGTATTA GGAAGAGCAT TTGAAGATAT GTGTGCTCAG 600 601 ATGTATTACA GGGGCAAAAT GTTTGGCTTT GTTCATCTTT ACAACGGCCA AGAAGCCGTT 660 661 TCGACTGGTT TCATTAAGCA CTTAAAGAAG GAAGACTCTG TCGTAAGCAC TTACCGTGAT 720 721 CACGTGCACG CCTTAAGCAA AGGCGTCCCT GCACGTGCCG TCATGAGCGA ACTCTTCGGC 780 781 AAGACCACCG GCTGCTGCCG CGGCCAAGGT GGGTCGATGC ATATGTTTTC GAGCGAACAC 840 841 AATTTGCTTG GTGGGTTTGC ATTTATCGGT GAAGGGATCC CCGTTGCCAC GGGGGCGGCT 900 901 TTCACCTCCA AGTATAAGAG GGAGGTTCTG AAGGAAGCGG ATTGTGATCA TGTCACGTTG 960 961 GCGTTTTTCG GAGATGGGAC TTGTAATAAT GGGCAGTTCT TTGAGTGTTT GAATATGGCC 1020 1021 GCGTTGTGGA AGCTGCCCAT TGTGTTTGTC GTTGAGAATA ATTTGTGGGC TATAGGGATG 1080 1081 TCGCATTTGA GGGCTACTTC TGATCCTCAG ATTTATAAGA AAGGACCGGC TTTTGGGATG 1140 1141 CCCGGTATTC ATGTCGATGG GATGGATGTT TTGAAGGTGA GGGAAGTGGC CAAGGAGGCC 1200 1201 ATTGGCAGGG CTAGGAGAGG AGAAGGTCCA ACATTGGTGG AATGCGAGAC ATATAGGTTT 1260 1261 AGAGGACACT CTTTGGCTGA CCCTGATGAG CTTCGTGACC CTGCTGAGAA GGCTCACTAT 1320 1321 GCTGCAAGAG ATCCTATCAC AGCCCTGAAG AAGTATCTAA TTGAGAACAG TCTGGCCAGT 1380 1381 GAAGCAGAGT TAAAGGCCAT AGATAAGAAG ATAGATGAGG TGGTCGAGGA TTCTGTTGAG 1440 1441 TTTGCAGATG AAAGCCCCCT TCCTTCTCGG AGCCAGCTGC TCGAAAATGT GTTTGCCGAT 1500 1501 CCAAAAGGTT TTGGAATTGG ACCTGATGGC CAATATAGAT GTGAGGATCC AAAGTTCACC 1560 1561 GAAGGCACTG CTCATGTCTA A 1581 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Intracellular membrane-bounded organelle | |
Molecular Function | Pyruvate dehydrogenase (acetyl-transferring) activity | |
Biological Process | Acetyl-CoA biosynthetic process from pyruvate |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Coc-2049 | Corchorus capsularis | 92.89 | 0.0 | 808 |
| LLPS-Ori-2411 | Oryza indica | 85.84 | 0.0 | 641 |
| LLPS-Org-1261 | Oryza glaberrima | 85.84 | 0.0 | 639 |
| LLPS-Prp-1284 | Prunus persica | 82.64 | 0.0 | 729 |
| LLPS-Sei-2466 | Setaria italica | 82.23 | 0.0 | 639 |
| LLPS-Amt-1386 | Amborella trichopoda | 78.72 | 0.0 | 692 |
| LLPS-Chr-0990 | Chlamydomonas reinhardtii | 71.09 | 0.0 | 547 |
| LLPS-Cym-0832 | Cyanidioschyzon merolae | 65.79 | 6e-143 | 422 |
| LLPS-Chc-1157 | Chondrus crispus | 64.58 | 1e-148 | 437 |
| LLPS-Gas-1278 | Galdieria sulphuraria | 60.36 | 2e-141 | 418 |
| LLPS-Tag-0857 | Taeniopygia guttata | 51.52 | 9e-27 | 108 |
| LLPS-Zem-0520 | Zea mays | 40.52 | 9e-80 | 261 |
| LLPS-Orbr-2205 | Oryza brachyantha | 40.48 | 1e-75 | 250 |
| LLPS-Hea-1335 | Helianthus annuus | 40.35 | 1e-77 | 256 |
| LLPS-Osl-1061 | Ostreococcus lucimarinus | 40.2 | 2e-64 | 221 |
| LLPS-Viv-0174 | Vitis vinifera | 40.17 | 1e-77 | 256 |
| LLPS-Sol-2295 | Solanum lycopersicum | 40.0 | 2e-76 | 253 |
| LLPS-Sah-3862 | Sarcophilus harrisii | 40.0 | 6e-77 | 254 |
| LLPS-Nia-2260 | Nicotiana attenuata | 40.0 | 6e-76 | 251 |
| LLPS-Meg-1021 | Meleagris gallopavo | 39.94 | 2e-68 | 232 |
| LLPS-Anp-1089 | Anas platyrhynchos | 39.94 | 1e-68 | 231 |
| LLPS-Sot-1054 | Solanum tuberosum | 39.88 | 9e-77 | 253 |
| LLPS-Tru-0781 | Triticum urartu | 39.88 | 3e-30 | 120 |
| LLPS-Sob-1486 | Sorghum bicolor | 39.88 | 4e-74 | 246 |
| LLPS-Ors-2238 | Oryza sativa | 39.88 | 5e-74 | 246 |
| LLPS-Brd-1072 | Brachypodium distachyon | 39.77 | 5e-78 | 257 |
| LLPS-Gaga-3914 | Gallus gallus | 39.77 | 8e-69 | 233 |
| LLPS-Art-1136 | Arabidopsis thaliana | 39.71 | 4e-75 | 249 |
| LLPS-Tra-2229 | Triticum aestivum | 39.6 | 2e-77 | 255 |
| LLPS-Gor-2633 | Gossypium raimondii | 39.59 | 1e-76 | 253 |
| LLPS-Pot-0824 | Populus trichocarpa | 39.51 | 8e-66 | 224 |
| LLPS-Lep-2180 | Leersia perrieri | 39.48 | 8e-77 | 254 |
| LLPS-Cus-2318 | Cucumis sativus | 39.36 | 2e-75 | 250 |
| LLPS-Pap-4269 | Pan paniscus | 39.34 | 7e-52 | 187 |
| LLPS-Orm-0585 | Oryza meridionalis | 39.3 | 1e-74 | 248 |
| LLPS-Met-1234 | Medicago truncatula | 39.23 | 2e-72 | 242 |
| LLPS-Crn-0557 | Cryptococcus neoformans | 39.21 | 2e-71 | 240 |
| LLPS-Via-1760 | Vigna angularis | 39.14 | 9e-70 | 236 |
| LLPS-Dac-1792 | Daucus carota | 39.12 | 8e-76 | 251 |
| LLPS-Glm-2588 | Glycine max | 39.12 | 3e-72 | 241 |
| LLPS-Brn-3162 | Brassica napus | 39.07 | 7e-74 | 246 |
| LLPS-Brr-0719 | Brassica rapa | 39.07 | 7e-74 | 246 |
| LLPS-Orgl-1763 | Oryza glumaepatula | 38.99 | 8e-75 | 248 |
| LLPS-Orni-2110 | Oryza nivara | 38.99 | 7e-74 | 246 |
| LLPS-Orb-0647 | Oryza barthii | 38.99 | 2e-74 | 247 |
| LLPS-Orr-0889 | Oryza rufipogon | 38.91 | 2e-67 | 228 |
| LLPS-Pes-2339 | Pelodiscus sinensis | 38.89 | 2e-68 | 232 |
| LLPS-Phv-0217 | Phaseolus vulgaris | 38.83 | 2e-66 | 225 |
| LLPS-Arl-2732 | Arabidopsis lyrata | 38.82 | 2e-73 | 244 |
| LLPS-Ran-0802 | Rattus norvegicus | 38.81 | 9e-74 | 246 |
| LLPS-Mum-4676 | Mus musculus | 38.81 | 4e-74 | 246 |
| LLPS-Ora-2673 | Ornithorhynchus anatinus | 38.78 | 9e-69 | 232 |
| LLPS-Bro-0736 | Brassica oleracea | 38.78 | 2e-73 | 244 |
| LLPS-Fia-1189 | Ficedula albicollis | 38.78 | 3e-67 | 229 |
| LLPS-Leo-0830 | Lepisosteus oculatus | 38.67 | 6e-74 | 246 |
| LLPS-Mea-3186 | Mesocricetus auratus | 38.51 | 2e-73 | 245 |
| LLPS-Mae-2057 | Manihot esculenta | 38.42 | 4e-65 | 223 |
| LLPS-Cae-2028 | Caenorhabditis elegans | 38.41 | 6e-66 | 226 |
| LLPS-Dar-3426 | Danio rerio | 38.37 | 3e-73 | 244 |
| LLPS-Anc-0122 | Anolis carolinensis | 38.33 | 4e-76 | 252 |
| LLPS-Ten-0221 | Tetraodon nigroviridis | 38.28 | 3e-72 | 242 |
| LLPS-Mod-4351 | Monodelphis domestica | 38.26 | 4e-75 | 249 |
| LLPS-Pof-0701 | Poecilia formosa | 38.25 | 5e-74 | 246 |
| LLPS-Fec-0524 | Felis catus | 38.24 | 1e-70 | 238 |
| LLPS-Mup-3057 | Mustela putorius furo | 38.21 | 6e-72 | 241 |
| LLPS-Dio-3942 | Dipodomys ordii | 38.21 | 4e-72 | 241 |
| LLPS-Tar-3150 | Takifugu rubripes | 38.18 | 3e-65 | 225 |
| LLPS-Asm-2302 | Astyanax mexicanus | 38.14 | 7e-74 | 246 |
| LLPS-Icp-1197 | Ictalurus punctatus | 38.14 | 5e-74 | 246 |
| LLPS-Hov-0115 | Hordeum vulgare | 38.08 | 6e-72 | 244 |
| LLPS-Loa-3946 | Loxodonta africana | 38.08 | 5e-75 | 249 |
| LLPS-Scf-1045 | Scleropages formosus | 38.07 | 4e-73 | 244 |
| LLPS-Myl-3586 | Myotis lucifugus | 38.02 | 8e-71 | 238 |
| LLPS-Blg-0670 | Blumeria graminis | 37.99 | 5e-63 | 218 |
| LLPS-Xim-0452 | Xiphophorus maculatus | 37.95 | 2e-73 | 247 |
| LLPS-Paa-2119 | Papio anubis | 37.91 | 1e-72 | 243 |
| LLPS-Tut-1755 | Tursiops truncatus | 37.91 | 5e-72 | 241 |
| LLPS-Php-1848 | Physcomitrella patens | 37.91 | 2e-69 | 237 |
| LLPS-Gog-3678 | Gorilla gorilla | 37.91 | 5e-73 | 243 |
| LLPS-Fud-3763 | Fukomys damarensis | 37.91 | 6e-72 | 241 |
| LLPS-Ict-4504 | Ictidomys tridecemlineatus | 37.91 | 8e-72 | 240 |
| LLPS-Nol-3197 | Nomascus leucogenys | 37.91 | 6e-71 | 238 |
| LLPS-Caf-2821 | Canis familiaris | 37.91 | 8e-72 | 240 |
| LLPS-Eqc-2160 | Equus caballus | 37.91 | 2e-71 | 239 |
| LLPS-Cap-0691 | Cavia porcellus | 37.91 | 5e-72 | 241 |
| LLPS-Pat-3430 | Pan troglodytes | 37.91 | 2e-72 | 243 |
| LLPS-Hos-0296 | Homo sapiens | 37.91 | 6e-73 | 243 |
| LLPS-Asni-0796 | Aspergillus niger | 37.88 | 2e-63 | 219 |
| LLPS-Ast-1231 | Aspergillus terreus | 37.88 | 4e-66 | 226 |
| LLPS-Asf-0825 | Aspergillus flavus | 37.85 | 1e-63 | 219 |
| LLPS-Aso-0479 | Aspergillus oryzae | 37.85 | 5e-64 | 219 |
| LLPS-Caj-0693 | Callithrix jacchus | 37.76 | 1e-73 | 245 |
| LLPS-Cis-1386 | Ciona savignyi | 37.74 | 3e-63 | 216 |
| LLPS-Ere-0625 | Erinaceus europaeus | 37.68 | 2e-66 | 226 |
| LLPS-Mal-0013 | Mandrillus leucophaeus | 37.61 | 9e-72 | 240 |
| LLPS-Maf-0584 | Macaca fascicularis | 37.61 | 4e-72 | 241 |
| LLPS-Cea-1635 | Cercocebus atys | 37.61 | 6e-72 | 241 |
| LLPS-Poa-4210 | Pongo abelii | 37.61 | 8e-72 | 240 |
| LLPS-Rhb-2988 | Rhinopithecus bieti | 37.61 | 1e-71 | 240 |
| LLPS-Man-4632 | Macaca nemestrina | 37.61 | 6e-72 | 241 |
| LLPS-Scm-2702 | Scophthalmus maximus | 37.58 | 2e-65 | 225 |
| LLPS-Sem-1609 | Selaginella moellendorffii | 37.42 | 2e-66 | 226 |
| LLPS-Orl-3043 | Oryzias latipes | 37.39 | 2e-73 | 244 |
| LLPS-Nef-1039 | Neosartorya fischeri | 37.27 | 3e-66 | 226 |
| LLPS-Drm-1058 | Drosophila melanogaster | 37.16 | 1e-63 | 221 |
| LLPS-Ova-3461 | Ovis aries | 37.1 | 3e-72 | 241 |
| LLPS-Bot-1299 | Bos taurus | 37.1 | 2e-69 | 234 |
| LLPS-Aon-4581 | Aotus nancymaae | 37.1 | 4e-64 | 221 |
| LLPS-Sus-3185 | Sus scrofa | 37.1 | 4e-64 | 220 |
| LLPS-Otg-3185 | Otolemur garnettii | 37.1 | 2e-64 | 222 |
| LLPS-Mua-0794 | Musa acuminata | 37.07 | 2e-58 | 202 |
| LLPS-Urm-3344 | Ursus maritimus | 37.06 | 1e-68 | 232 |
| LLPS-Orc-0965 | Oryctolagus cuniculus | 36.95 | 4e-72 | 241 |
| LLPS-Xet-1836 | Xenopus tropicalis | 36.87 | 1e-73 | 246 |
| LLPS-Aim-0286 | Ailuropoda melanoleuca | 36.81 | 5e-72 | 241 |
| LLPS-Mam-4296 | Macaca mulatta | 36.81 | 1e-63 | 220 |
| LLPS-Gaa-2364 | Gasterosteus aculeatus | 36.78 | 5e-72 | 241 |
| LLPS-Lac-3750 | Latimeria chalumnae | 36.73 | 7e-72 | 241 |
| LLPS-Cii-0064 | Ciona intestinalis | 36.72 | 7e-66 | 224 |
| LLPS-Orn-1305 | Oreochromis niloticus | 36.56 | 6e-70 | 236 |
| LLPS-Cas-0515 | Carlito syrichta | 36.52 | 1e-62 | 217 |
| LLPS-Orp-0849 | Oryza punctata | 36.31 | 2e-57 | 201 |
| LLPS-Put-0339 | Puccinia triticina | 34.59 | 6e-43 | 163 |
| LLPS-Asc-0275 | Aspergillus clavatus | 32.52 | 2e-40 | 154 |
| LLPS-Asfu-0296 | Aspergillus fumigatus | 32.17 | 9e-41 | 155 |
| LLPS-Vir-0336 | Vigna radiata | 32.09 | 2e-54 | 195 |