LLPS-Prp-1284
PRUPE_2G197700
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Pyruvate dehydrogenase E1 component subunit alpha |
| Gene Name: | PRUPE_2G197700, PRUPE_ppa006008mg |
| Ensembl Gene: | PRUPE_2G197700 |
| Ensembl Protein: | ONI23601 |
| Organism: | Prunus persica |
| Taxa ID: | 3760 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus | Predicted from orthologs | (View) |
▼ FUNCTION
| The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ONI23601 | ONI23601 |
| UniProt | M5XCJ6, M5XCJ6_PRUPE | |
| GeneBank | KB638974, CM007652 | ONI23601.1, EMJ19233.1 |
| RefSeq | XM_007217972.1 | XP_007218034.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSFSATNLAQ PLQLNTATPR SNDKPSLLLP KTSSFLGSTR NFRPTSLSAN PSHSNAHRRS 60 61 AVVAVSEAVK EKKLHASTNL LITKEEGLEL YEDMVLGRSF EDMCAQMYYR GKMFGFVHLY 120 121 NGQEAVSTGF IKLTKKEDSV VSTYRDHVHS LSKGVPAREV MSELFGKATG CCRGQGGSMH 180 181 MFSKEYNVLG GFAFIGEGIP VATGAAFSSR YRREVLKQAD CDHVTLAFFG DGTANNGQFF 240 241 ECLNMAALWK LPIVFVVENN LWAIGMSHLR ATSDPEIWKK GPAFGMPGVH VDGMDVLKVR 300 301 EVAKEAIGRA RRGEGPTLVE CETYRFRGHS LADPDELRDP AEKAHYAARD PITALKKYIL 360 361 ENNLATEQEL KAIHKKIDEL VEDAVEFADE SPLPPRSQLL ENVFADPKGF GIGPDGSYRC 420 421 EDPKFTQGTA HV 432 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCCTTCT CTGCCACCAA TTTGGCCCAG CCCCTCCAAC TCAACACCGC CACCCCCAGA 60 61 TCCAATGACA AGCCCTCCTT GTTGTTGCCC AAGACCTCAT CTTTTCTCGG ATCCACCCGC 120 121 AACTTCCGAC CCACTTCCTT ATCTGCTAAC CCCAGTCACT CGAATGCCCA CCGTCGATCC 180 181 GCTGTCGTTG CTGTCTCCGA AGCTGTGAAG GAGAAGAAGC TCCATGCATC CACCAATCTG 240 241 CTTATAACAA AAGAGGAAGG CTTGGAGCTG TATGAAGACA TGGTATTGGG TAGGTCTTTT 300 301 GAGGACATGT GTGCTCAGAT GTATTATAGA GGCAAGATGT TCGGGTTTGT TCATCTTTAC 360 361 AATGGCCAAG AAGCTGTGTC AACTGGGTTT ATCAAGCTTA CAAAGAAGGA AGATTCAGTG 420 421 GTGAGCACTT ATCGTGATCA CGTACACTCC TTGAGTAAGG GTGTACCTGC TCGTGAGGTG 480 481 ATGAGTGAGC TCTTTGGAAA GGCCACTGGT TGTTGCCGAG GCCAAGGTGG TTCAATGCAC 540 541 ATGTTTTCAA AAGAGTACAA TGTGCTTGGT GGGTTTGCAT TTATTGGTGA AGGGATACCA 600 601 GTAGCAACAG GTGCAGCATT CTCCTCTAGA TACAGGAGGG AAGTGCTGAA ACAAGCAGAC 660 661 TGTGATCACG TGACATTGGC CTTTTTCGGA GATGGGACTG CTAATAATGG CCAGTTCTTT 720 721 GAGTGTTTGA ACATGGCAGC ATTGTGGAAA TTGCCAATTG TTTTTGTTGT GGAGAACAAT 780 781 TTGTGGGCTA TTGGAATGTC ACATTTGAGG GCTACTTCTG ATCCAGAAAT TTGGAAGAAG 840 841 GGCCCTGCAT TTGGTATGCC TGGTGTTCAT GTGGATGGGA TGGATGTTTT GAAGGTGAGG 900 901 GAGGTGGCAA AGGAGGCGAT TGGAAGGGCC AGGAGAGGAG AAGGGCCAAC ATTGGTGGAA 960 961 TGTGAAACAT ACAGGTTCAG AGGACATTCA TTGGCTGATC CCGATGAGCT TCGTGACCCT 1020 1021 GCTGAGAAGG CACACTATGC TGCCAGAGAC CCCATCACAG CCTTAAAGAA ATACATACTT 1080 1081 GAGAACAATT TGGCCACTGA ACAAGAGTTG AAGGCCATAC ATAAGAAGAT TGATGAGTTG 1140 1141 GTTGAGGATG CCGTTGAGTT CGCAGATGAG AGCCCACTTC CACCTCGCAG CCAGCTGCTC 1200 1201 GAGAATGTGT TTGCCGATCC AAAGGGTTTT GGAATCGGCC CTGATGGCAG CTACAGATGT 1260 1261 GAAGATCCTA AGTTCACTCA GGGCACTGCT CATGTCTAA 1299 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Intracellular membrane-bounded organelle | |
Molecular Function | Pyruvate dehydrogenase (acetyl-transferring) activity | |
Biological Process | Acetyl-CoA biosynthetic process from pyruvate |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Org-1261 | Oryza glaberrima | 86.97 | 0.0 | 646 |
| LLPS-Ori-2411 | Oryza indica | 86.97 | 0.0 | 647 |
| LLPS-Sei-2466 | Setaria italica | 86.12 | 0.0 | 641 |
| LLPS-Coc-2049 | Corchorus capsularis | 83.75 | 0.0 | 735 |
| LLPS-Thc-2353 | Theobroma cacao | 82.22 | 0.0 | 721 |
| LLPS-Amt-1386 | Amborella trichopoda | 78.26 | 0.0 | 689 |
| LLPS-Chr-0990 | Chlamydomonas reinhardtii | 70.99 | 0.0 | 536 |
| LLPS-Cym-0832 | Cyanidioschyzon merolae | 65.79 | 1e-145 | 425 |
| LLPS-Chc-1157 | Chondrus crispus | 64.26 | 1e-148 | 434 |
| LLPS-Gas-1278 | Galdieria sulphuraria | 61.28 | 2e-141 | 415 |
| LLPS-Tag-0857 | Taeniopygia guttata | 50.51 | 6e-27 | 108 |
| LLPS-Sob-1486 | Sorghum bicolor | 41.67 | 3e-78 | 254 |
| LLPS-Hea-1335 | Helianthus annuus | 41.67 | 4e-83 | 267 |
| LLPS-Viv-0174 | Vitis vinifera | 41.38 | 8e-81 | 261 |
| LLPS-Orbr-2205 | Oryza brachyantha | 41.37 | 1e-78 | 254 |
| LLPS-Gor-2633 | Gossypium raimondii | 41.06 | 1e-80 | 261 |
| LLPS-Orm-0585 | Oryza meridionalis | 41.06 | 2e-79 | 258 |
| LLPS-Pot-0824 | Populus trichocarpa | 41.05 | 1e-69 | 232 |
| LLPS-Tru-0781 | Triticum urartu | 41.04 | 2e-31 | 123 |
| LLPS-Art-1136 | Arabidopsis thaliana | 40.88 | 9e-80 | 258 |
| LLPS-Met-1234 | Medicago truncatula | 40.88 | 2e-77 | 253 |
| LLPS-Orr-0889 | Oryza rufipogon | 40.84 | 3e-72 | 238 |
| LLPS-Orb-0647 | Oryza barthii | 40.77 | 6e-79 | 256 |
| LLPS-Orni-2110 | Oryza nivara | 40.77 | 2e-78 | 255 |
| LLPS-Orgl-1763 | Oryza glumaepatula | 40.77 | 2e-79 | 258 |
| LLPS-Ors-2238 | Oryza sativa | 40.76 | 7e-79 | 256 |
| LLPS-Osl-1061 | Ostreococcus lucimarinus | 40.51 | 1e-65 | 221 |
| LLPS-Brd-1072 | Brachypodium distachyon | 40.51 | 4e-81 | 262 |
| LLPS-Sol-2295 | Solanum lycopersicum | 40.41 | 3e-79 | 257 |
| LLPS-Nia-2260 | Nicotiana attenuata | 40.4 | 9e-80 | 258 |
| LLPS-Anp-1089 | Anas platyrhynchos | 40.35 | 1e-73 | 242 |
| LLPS-Zem-0520 | Zea mays | 40.29 | 3e-80 | 259 |
| LLPS-Sah-3862 | Sarcophilus harrisii | 40.24 | 5e-81 | 262 |
| LLPS-Brr-0719 | Brassica rapa | 40.23 | 2e-78 | 254 |
| LLPS-Brn-3162 | Brassica napus | 40.23 | 2e-78 | 254 |
| LLPS-Lep-2180 | Leersia perrieri | 40.23 | 8e-80 | 258 |
| LLPS-Tra-2675 | Triticum aestivum | 40.23 | 7e-80 | 258 |
| LLPS-Meg-1021 | Meleagris gallopavo | 40.17 | 7e-73 | 241 |
| LLPS-Leo-0830 | Lepisosteus oculatus | 40.12 | 8e-80 | 259 |
| LLPS-Cus-2318 | Cucumis sativus | 40.11 | 5e-80 | 259 |
| LLPS-Gaga-3914 | Gallus gallus | 40.06 | 4e-73 | 241 |
| LLPS-Glm-2588 | Glycine max | 40.0 | 2e-75 | 247 |
| LLPS-Arl-2732 | Arabidopsis lyrata | 40.0 | 3e-78 | 254 |
| LLPS-Bro-0736 | Brassica oleracea | 39.94 | 7e-78 | 253 |
| LLPS-Mae-2057 | Manihot esculenta | 39.88 | 3e-69 | 231 |
| LLPS-Dac-1792 | Daucus carota | 39.83 | 6e-80 | 259 |
| LLPS-Sot-1635 | Solanum tuberosum | 39.83 | 4e-78 | 254 |
| LLPS-Via-1760 | Vigna angularis | 39.58 | 2e-72 | 241 |
| LLPS-Scf-2665 | Scleropages formosus | 39.58 | 6e-78 | 255 |
| LLPS-Hov-0115 | Hordeum vulgare | 39.48 | 9e-76 | 251 |
| LLPS-Mod-4351 | Monodelphis domestica | 39.4 | 2e-79 | 258 |
| LLPS-Ere-0625 | Erinaceus europaeus | 39.4 | 5e-70 | 233 |
| LLPS-Ora-2673 | Ornithorhynchus anatinus | 39.36 | 2e-72 | 239 |
| LLPS-Fia-1189 | Ficedula albicollis | 39.31 | 6e-72 | 238 |
| LLPS-Phv-0217 | Phaseolus vulgaris | 39.3 | 2e-69 | 230 |
| LLPS-Pof-0701 | Poecilia formosa | 39.22 | 2e-78 | 255 |
| LLPS-Anc-0122 | Anolis carolinensis | 39.19 | 2e-81 | 263 |
| LLPS-Ten-0221 | Tetraodon nigroviridis | 39.1 | 7e-78 | 254 |
| LLPS-Crn-0557 | Cryptococcus neoformans | 39.08 | 1e-69 | 233 |
| LLPS-Asm-2302 | Astyanax mexicanus | 39.04 | 3e-78 | 254 |
| LLPS-Loa-3946 | Loxodonta africana | 38.99 | 7e-77 | 251 |
| LLPS-Pap-4269 | Pan paniscus | 38.97 | 1e-52 | 187 |
| LLPS-Fec-0524 | Felis catus | 38.92 | 9e-73 | 240 |
| LLPS-Pes-2339 | Pelodiscus sinensis | 38.89 | 3e-70 | 233 |
| LLPS-Dar-3426 | Danio rerio | 38.81 | 6e-78 | 254 |
| LLPS-Mea-3186 | Mesocricetus auratus | 38.81 | 3e-76 | 249 |
| LLPS-Mum-4676 | Mus musculus | 38.81 | 3e-76 | 249 |
| LLPS-Aon-4581 | Aotus nancymaae | 38.81 | 2e-67 | 227 |
| LLPS-Tar-3822 | Takifugu rubripes | 38.81 | 5e-77 | 251 |
| LLPS-Dio-3942 | Dipodomys ordii | 38.81 | 9e-76 | 248 |
| LLPS-Ran-0802 | Rattus norvegicus | 38.81 | 4e-76 | 249 |
| LLPS-Mup-3057 | Mustela putorius furo | 38.81 | 1e-75 | 248 |
| LLPS-Xim-0452 | Xiphophorus maculatus | 38.55 | 4e-78 | 256 |
| LLPS-Pat-1993 | Pan troglodytes | 38.51 | 3e-67 | 226 |
| LLPS-Hos-1031 | Homo sapiens | 38.51 | 3e-67 | 227 |
| LLPS-Man-3836 | Macaca nemestrina | 38.51 | 5e-67 | 226 |
| LLPS-Eqc-2160 | Equus caballus | 38.51 | 3e-75 | 246 |
| LLPS-Cap-0691 | Cavia porcellus | 38.51 | 9e-76 | 248 |
| LLPS-Caf-2821 | Canis familiaris | 38.51 | 2e-75 | 247 |
| LLPS-Poa-0582 | Pongo abelii | 38.51 | 1e-66 | 226 |
| LLPS-Mam-4296 | Macaca mulatta | 38.51 | 3e-67 | 227 |
| LLPS-Cas-0515 | Carlito syrichta | 38.51 | 1e-66 | 225 |
| LLPS-Ict-4504 | Ictidomys tridecemlineatus | 38.51 | 2e-75 | 247 |
| LLPS-Nol-3197 | Nomascus leucogenys | 38.51 | 2e-73 | 241 |
| LLPS-Maf-0137 | Macaca fascicularis | 38.51 | 5e-67 | 226 |
| LLPS-Cea-3575 | Cercocebus atys | 38.51 | 3e-67 | 227 |
| LLPS-Gog-2378 | Gorilla gorilla | 38.51 | 3e-67 | 226 |
| LLPS-Caj-1340 | Callithrix jacchus | 38.51 | 2e-67 | 227 |
| LLPS-Fud-3763 | Fukomys damarensis | 38.51 | 1e-75 | 248 |
| LLPS-Aim-0286 | Ailuropoda melanoleuca | 38.51 | 8e-76 | 248 |
| LLPS-Scm-2702 | Scophthalmus maximus | 38.48 | 6e-71 | 237 |
| LLPS-Icp-1197 | Ictalurus punctatus | 38.44 | 9e-78 | 253 |
| LLPS-Orp-0849 | Oryza punctata | 38.39 | 2e-62 | 213 |
| LLPS-Myl-1649 | Myotis lucifugus | 38.35 | 6e-76 | 248 |
| LLPS-Ast-1273 | Aspergillus terreus | 38.34 | 6e-66 | 223 |
| LLPS-Rhb-2988 | Rhinopithecus bieti | 38.21 | 6e-73 | 241 |
| LLPS-Paa-2119 | Papio anubis | 38.21 | 3e-74 | 244 |
| LLPS-Cae-2028 | Caenorhabditis elegans | 38.14 | 8e-71 | 236 |
| LLPS-Otg-3185 | Otolemur garnettii | 38.05 | 7e-68 | 228 |
| LLPS-Sus-3185 | Sus scrofa | 38.05 | 1e-67 | 227 |
| LLPS-Bot-1071 | Bos taurus | 38.05 | 7e-76 | 248 |
| LLPS-Ova-3461 | Ovis aries | 38.05 | 7e-76 | 248 |
| LLPS-Xet-1836 | Xenopus tropicalis | 38.01 | 5e-79 | 257 |
| LLPS-Mua-0794 | Musa acuminata | 37.99 | 2e-60 | 205 |
| LLPS-Php-1848 | Physcomitrella patens | 37.93 | 1e-72 | 243 |
| LLPS-Gaa-2364 | Gasterosteus aculeatus | 37.93 | 5e-77 | 251 |
| LLPS-Tut-1755 | Tursiops truncatus | 37.91 | 3e-74 | 244 |
| LLPS-Mal-0013 | Mandrillus leucophaeus | 37.91 | 2e-73 | 242 |
| LLPS-Nef-1039 | Neosartorya fischeri | 37.76 | 1e-67 | 227 |
| LLPS-Orc-0567 | Oryctolagus cuniculus | 37.76 | 2e-75 | 247 |
| LLPS-Cis-1386 | Ciona savignyi | 37.74 | 5e-64 | 215 |
| LLPS-Urm-3344 | Ursus maritimus | 37.72 | 2e-70 | 234 |
| LLPS-Orl-3043 | Oryzias latipes | 37.69 | 2e-77 | 252 |
| LLPS-Lac-3750 | Latimeria chalumnae | 37.46 | 1e-76 | 251 |
| LLPS-Orn-1305 | Oreochromis niloticus | 37.46 | 1e-74 | 245 |
| LLPS-Asni-0796 | Aspergillus niger | 36.97 | 2e-64 | 218 |
| LLPS-Cii-0064 | Ciona intestinalis | 36.9 | 2e-68 | 228 |
| LLPS-Drm-1058 | Drosophila melanogaster | 36.9 | 3e-65 | 223 |
| LLPS-Sem-1609 | Selaginella moellendorffii | 36.61 | 3e-68 | 229 |
| LLPS-Aso-0479 | Aspergillus oryzae | 36.5 | 2e-63 | 215 |
| LLPS-Asf-0825 | Aspergillus flavus | 36.5 | 8e-63 | 214 |
| LLPS-Blg-0670 | Blumeria graminis | 36.14 | 3e-61 | 210 |
| LLPS-Put-0339 | Puccinia triticina | 34.04 | 4e-44 | 164 |
| LLPS-Vir-0336 | Vigna radiata | 33.07 | 5e-57 | 200 |
| LLPS-Asfu-0296 | Aspergillus fumigatus | 32.06 | 8e-40 | 151 |
| LLPS-Asc-0275 | Aspergillus clavatus | 30.46 | 7e-40 | 151 |