• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Put-0339
PTTG_01684

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Pyruvate dehydrogenase E1 component subunit alpha
Gene Name: PTTG_01684
Ensembl Gene: PTTG_01684
Ensembl Protein: PTTG_01684P0
Organism: Puccinia triticina
Taxa ID: 630390
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblPTTG_01684T0PTTG_01684P0
UniProtA0A180GG93, A0A180GG93_PUCT1
GeneBankADAS02000082OAV91342.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAHLTTNAFT  RRFLTATTRP  TVNKLNTSST  RALSSLAAQH  PQPRSLKAHS  SGSPLSTFNS  60
61    RLIQTAADSS  AVNPDKIPSN  DGDKFNITLD  ADYYQTYKCD  APSLELEMTK  AELVQMYRWM  120
121   VTMRRMEMAA  DALYKQKMIR  GFCHLAIGQE  AAARTGCRAG  NGIVGAQVPV  GAGIALAQKY  180
181   LNQDDKHATF  IMYGDGASNQ  GQVFEAFNMA  KLWNLPAVFV  CENNLYGMGT  SAERSSSNTK  240
241   YFTRGDQIPG  LQANGMDVLS  VHNACKYAKE  WTTSGKGPLL  LEFITYRYGG  HSMSDPGTTY  300
301   RSREEIQHMR  STNDPITGLR  NRLLEWNVIK  EADLKAIDKQ  AKAEVDVAVE  EAKKSPEPDP  360
361   ATDMWTDIYY  KGTAPKWMRG  REKEEVHRYK  PEECKGTHMP  VDNDT  405
Nucleotide CDS Sequence (FASTA)
1     ATGGCCCATC  TCACCACCAA  CGCCTTCACC  CGCCGGTTCC  TCACAGCCAC  CACTCGTCCG  60
61    ACAGTTAACA  AACTCAATAC  CTCGTCGACC  CGGGCACTTT  CCTCCCTGGC  TGCTCAACAC  120
121   CCTCAACCCC  GATCACTAAA  GGCTCATTCC  TCTGGATCAC  CTTTGAGTAC  CTTTAACTCT  180
181   CGTCTAATTC  AAACAGCTGC  GGACTCCTCG  GCCGTCAACC  CAGACAAAAT  ACCCTCGAAT  240
241   GATGGCGACA  AGTTCAACAT  CACTTTAGAC  GCTGATTATT  ATCAAACCTA  CAAGTGTGAT  300
301   GCCCCGTCGT  TGGAGCTAGA  AATGACCAAG  GCAGAACTAG  TGCAGATGTA  CCGATGGATG  360
361   GTCACCATGC  GACGGATGGA  GATGGCTGCA  GATGCGCTCT  ACAAGCAGAA  GATGATCCGA  420
421   GGATTCTGTC  ATCTGGCGAT  CGGTCAGGAG  GCCGCCGCAA  GGACGGGATG  TCGAGCGGGA  480
481   AATGGTATCG  TTGGTGCCCA  AGTACCCGTC  GGAGCAGGCA  TCGCGCTTGC  TCAGAAATAC  540
541   CTGAACCAAG  ACGACAAGCA  TGCCACCTTC  ATCATGTATG  GTGATGGAGC  GTCTAATCAA  600
601   GGGCAAGTCT  TTGAAGCATT  CAACATGGCC  AAACTGTGGA  ACCTTCCTGC  TGTTTTCGTG  660
661   TGCGAAAACA  ACCTTTACGG  AATGGGCACG  AGCGCAGAGC  GTTCGAGTTC  CAACACCAAG  720
721   TACTTCACCA  GAGGCGACCA  AATCCCCGGT  CTTCAGGCCA  ACGGGATGGA  TGTACTATCG  780
781   GTTCACAATG  CGTGCAAGTA  TGCCAAGGAA  TGGACAACGT  CAGGCAAAGG  GCCACTGTTG  840
841   CTTGAGTTCA  TCACCTACCG  ATACGGTGGA  CATTCGATGT  CTGACCCTGG  GACGACCTAC  900
901   CGAAGCCGAG  AGGAAATCCA  GCACATGCGT  AGCACCAACG  ACCCCATCAC  TGGTCTCCGT  960
961   AACCGATTGC  TCGAATGGAA  CGTCATCAAG  GAAGCCGACT  TGAAGGCTAT  CGACAAGCAG  1020
1021  GCCAAGGCCG  AAGTCGATGT  TGCCGTCGAG  GAAGCTAAGA  AGAGCCCCGA  GCCCGACCCA  1080
1081  GCTACTGATA  TGTGGACCGA  TATCTACTAC  AAAGGTACCG  CGCCCAAGTG  GATGCGTGGT  1140
1141  CGTGAAAAAG  AAGAGGTCCA  TCGCTACAAA  CCGGAAGAGT  GCAAAGGTAC  GCATATGCCT  1200
1201  GTCGACAATG  ATACG  1215

▼ KEYWORD

ID
Family
Complete proteome
Oxidoreductase
Pyruvate
Reference proteome
Thiamine pyrophosphate

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Intracellular membrane-bounded organelle
Molecular Function
Pyruvate dehydrogenase (acetyl-transferring) activity
Biological Process
Acetyl-CoA biosynthetic process from pyruvate

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tag-0857Taeniopygia guttata62.382e-40 145
LLPS-Crn-0557Cryptococcus neoformans57.361e-140 414
LLPS-Nef-1039Neosartorya fischeri49.63e-118 357
LLPS-Asni-1516Aspergillus niger49.362e-118 358
LLPS-Ast-1231Aspergillus terreus48.941e-115 351
LLPS-Blg-0670Blumeria graminis48.581e-114 348
LLPS-Tru-0781Triticum urartu48.455e-42 152
LLPS-Asf-0825Aspergillus flavus46.884e-102 315
LLPS-Aso-0479Aspergillus oryzae46.833e-100 310
LLPS-Dar-3426Danio rerio46.431e-90 286
LLPS-Pof-0701Poecilia formosa46.291e-87 278
LLPS-Ten-0221Tetraodon nigroviridis45.991e-88 281
LLPS-Anc-0122Anolis carolinensis45.561e-89 283
LLPS-Sei-1164Setaria italica45.521e-31 123
LLPS-Tar-3822Takifugu rubripes45.47e-90 283
LLPS-Sol-2389Solanum lycopersicum45.41e-89 283
LLPS-Phv-0217Phaseolus vulgaris45.393e-84 268
LLPS-Scm-2702Scophthalmus maximus45.242e-85 274
LLPS-Leo-0830Lepisosteus oculatus45.223e-91 287
LLPS-Xet-1836Xenopus tropicalis45.053e-86 275
LLPS-Cis-1386Ciona savignyi44.981e-78 252
LLPS-Dac-1792Daucus carota44.942e-88 280
LLPS-Sah-3031Sarcophilus harrisii44.921e-84 270
LLPS-Gaa-2364Gasterosteus aculeatus44.861e-88 280
LLPS-Otg-0683Otolemur garnettii44.851e-75 246
LLPS-Zem-0520Zea mays44.645e-83 266
LLPS-Xim-0452Xiphophorus maculatus44.544e-85 273
LLPS-Sot-1635Solanum tuberosum44.546e-89 281
LLPS-Icp-1197Ictalurus punctatus44.542e-86 275
LLPS-Myl-1649Myotis lucifugus44.517e-87 276
LLPS-Ova-3461Ovis aries44.518e-88 278
LLPS-Mup-3057Mustela putorius furo44.511e-87 278
LLPS-Dio-3942Dipodomys ordii44.518e-88 278
LLPS-Bot-1071Bos taurus44.519e-88 278
LLPS-Mum-4676Mus musculus44.519e-88 278
LLPS-Fia-1189Ficedula albicollis44.482e-83 267
LLPS-Art-0953Arabidopsis thaliana44.483e-86 275
LLPS-Arl-0506Arabidopsis lyrata44.481e-86 275
LLPS-Via-1760Vigna angularis44.482e-86 276
LLPS-Ora-2673Ornithorhynchus anatinus44.488e-85 271
LLPS-Php-0348Physcomitrella patens44.311e-81 263
LLPS-Anp-1089Anas platyrhynchos44.253e-86 274
LLPS-Scf-2665Scleropages formosus44.253e-85 273
LLPS-Cas-0515Carlito syrichta44.212e-84 270
LLPS-Ict-4504Ictidomys tridecemlineatus44.212e-87 277
LLPS-Caf-2821Canis familiaris44.212e-87 277
LLPS-Eqc-2160Equus caballus44.213e-88 279
LLPS-Cap-0691Cavia porcellus44.212e-87 278
LLPS-Fec-3128Felis catus44.212e-87 277
LLPS-Aim-0286Ailuropoda melanoleuca44.218e-87 276
LLPS-Tut-1755Tursiops truncatus44.212e-86 275
LLPS-Fud-3763Fukomys damarensis44.217e-87 276
LLPS-Mea-3186Mesocricetus auratus44.212e-87 277
LLPS-Sus-3185Sus scrofa44.211e-84 270
LLPS-Orr-0889Oryza rufipogon44.084e-77 250
LLPS-Cii-0064Ciona intestinalis44.072e-85 272
LLPS-Brd-1072Brachypodium distachyon44.058e-85 270
LLPS-Tra-2675Triticum aestivum44.052e-83 267
LLPS-Sem-1609Selaginella moellendorffii44.053e-80 259
LLPS-Nol-3197Nomascus leucogenys43.992e-83 267
LLPS-Cae-2028Caenorhabditis elegans43.991e-85 273
LLPS-Poa-0582Pongo abelii43.925e-83 268
LLPS-Mam-4296Macaca mulatta43.925e-84 270
LLPS-Pap-3024Pan paniscus43.924e-83 268
LLPS-Pat-1993Pan troglodytes43.924e-84 270
LLPS-Hos-1031Homo sapiens43.925e-84 270
LLPS-Man-3836Macaca nemestrina43.926e-84 270
LLPS-Ran-0802Rattus norvegicus43.924e-86 274
LLPS-Ere-0625Erinaceus europaeus43.925e-84 268
LLPS-Gog-2378Gorilla gorilla43.924e-84 270
LLPS-Caj-1340Callithrix jacchus43.924e-84 270
LLPS-Maf-0137Macaca fascicularis43.921e-83 269
LLPS-Aon-4581Aotus nancymaae43.921e-83 269
LLPS-Cea-3575Cercocebus atys43.925e-84 270
LLPS-Orm-0585Oryza meridionalis43.841e-81 263
LLPS-Urm-3344Ursus maritimus43.846e-82 263
LLPS-Ors-2238Oryza sativa43.843e-81 262
LLPS-Orgl-1763Oryza glumaepatula43.844e-79 256
LLPS-Orb-0647Oryza barthii43.842e-81 261
LLPS-Ori-0363Oryza indica43.843e-81 262
LLPS-Gaga-3914Gallus gallus43.752e-84 270
LLPS-Meg-1021Meleagris gallopavo43.752e-84 270
LLPS-Pes-2339Pelodiscus sinensis43.684e-85 271
LLPS-Orc-0567Oryctolagus cuniculus43.682e-87 278
LLPS-Orn-1305Oreochromis niloticus43.686e-86 274
LLPS-Asm-2833Astyanax mexicanus43.688e-81 260
LLPS-Glm-2588Glycine max43.665e-88 279
LLPS-Orbr-2205Oryza brachyantha43.548e-82 262
LLPS-Mod-4351Monodelphis domestica43.543e-85 272
LLPS-Orni-2110Oryza nivara43.548e-81 260
LLPS-Orl-3043Oryzias latipes43.391e-87 278
LLPS-Nia-2260Nicotiana attenuata43.381e-86 275
LLPS-Lac-3750Latimeria chalumnae43.322e-85 272
LLPS-Mal-0043Mandrillus leucophaeus43.287e-70 232
LLPS-Hov-0115Hordeum vulgare43.249e-76 250
LLPS-Hea-1335Helianthus annuus43.211e-87 278
LLPS-Viv-0174Vitis vinifera43.186e-87 276
LLPS-Loa-3946Loxodonta africana43.16e-85 271
LLPS-Cus-2318Cucumis sativus43.17e-88 279
LLPS-Paa-2119Papio anubis42.931e-85 273
LLPS-Lep-2180Leersia perrieri42.828e-83 265
LLPS-Rhb-2988Rhinopithecus bieti42.662e-84 270
LLPS-Sob-1486Sorghum bicolor42.639e-83 265
LLPS-Coc-0057Corchorus capsularis42.545e-86 274
LLPS-Chr-0340Chlamydomonas reinhardtii42.394e-81 261
LLPS-Bro-2446Brassica oleracea42.332e-88 280
LLPS-Brn-1136Brassica napus42.332e-88 280
LLPS-Met-1234Medicago truncatula42.252e-79 256
LLPS-Brr-1329Brassica rapa42.061e-89 283
LLPS-Mae-2057Manihot esculenta41.971e-84 270
LLPS-Pot-2806Populus trichocarpa41.975e-84 268
LLPS-Gor-2633Gossypium raimondii41.851e-86 275
LLPS-Drm-1058Drosophila melanogaster40.992e-75 248
LLPS-Vir-0336Vigna radiata39.833e-73 242
LLPS-Mua-0794Musa acuminata39.213e-63 212
LLPS-Asfu-0296Aspergillus fumigatus39.061e-57 199
LLPS-Asc-0275Aspergillus clavatus37.949e-65 217
LLPS-Orp-0849Oryza punctata37.545e-58 200
LLPS-Thc-2353Theobroma cacao34.594e-40 154
LLPS-Prp-1284Prunus persica34.042e-40 154
LLPS-Org-1261Oryza glaberrima33.434e-41 154
LLPS-Amt-1386Amborella trichopoda32.324e-38 147
LLPS-Chc-1157Chondrus crispus30.874e-32 129
LLPS-Gas-1278Galdieria sulphuraria30.74e-31 126
LLPS-Usm-0276Ustilago maydis30.077e-0755.8
LLPS-Cym-0832Cyanidioschyzon merolae29.876e-34 134
LLPS-Osl-1061Ostreococcus lucimarinus29.324e-1580.5