DrLLPS - Data resource of LLPS

LLPS-Hov-0115

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Pyruvate dehydrogenase E1 component subunit alpha
Ensembl Gene:	HORVU7Hr1G040460
Ensembl Protein:	HORVU7Hr1G040460.2
Organism:	Hordeum vulgare
Taxa ID:	112509
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Arabidopsis thaliana	LLPS-Art-0953	Q8H1Y0	Client	Nucleolus	75.70	0.0	610

▼ FUNCTION

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	HORVU7Hr1G040460.2	HORVU7Hr1G040460.2
Ensembl	HORVU7Hr1G040460.6	HORVU7Hr1G040460.6
Ensembl	HORVU7Hr1G040460.8	HORVU7Hr1G040460.8
Ensembl	HORVU7Hr1G040460.10	HORVU7Hr1G040460.10
Ensembl	HORVU7Hr1G040460.4	HORVU7Hr1G040460.4
Ensembl	HORVU7Hr1G040460.12	HORVU7Hr1G040460.12
Ensembl	HORVU7Hr1G040460.14	HORVU7Hr1G040460.14
Ensembl	HORVU7Hr1G040460.5	HORVU7Hr1G040460.5
Ensembl	HORVU7Hr1G040460.13	HORVU7Hr1G040460.13
Ensembl	HORVU7Hr1G040460.9	HORVU7Hr1G040460.9
Ensembl	HORVU7Hr1G040460.11	HORVU7Hr1G040460.11
Ensembl	HORVU7Hr1G040460.15	HORVU7Hr1G040460.15
Ensembl	HORVU7Hr1G040460.1	HORVU7Hr1G040460.1
Ensembl	HORVU7Hr1G040460.7	HORVU7Hr1G040460.7
Ensembl	HORVU7Hr1G040460.3	HORVU7Hr1G040460.3
UniProt		A0A287W6W0, A0A287W6W0_HORVV

▼ SEQUENCE

Protein Sequence (FASTA)
1 TAARRRCGAV GADLDRRSLA HGGNAQPCTC LAPFPPSPRR STGHAARPAV PRHRAPANPR 60 61 HAPPPRPQLP LPNHLGDAPL RPRPLQPARC PCVPSQNPAD SLNPGSASNH AMAAAILRRL 120 121 SPAAAQRAPP RLLPLVRGVS DSTEPLTVET SIPFTSHIVD PPSREVTTTP RELAAAFRDM 180 181 ALMRRAEIAA DSLYKAKLIR GFCHLYDGQE AVAVGMEAAI TRRDAIITAY RDHCLYLARG 240 241 GDLVAAFAEL MGRVDGCSRG KGGSMHFYKK DANFYGGHGI VGAQVPLGCG LAFAQRYRKE 300 301 GTVTFDLYGD GAANQGQLFE ALNMAALWKL PVILVCENNH YGMGTAEWKA SKSPAYYKRG 360 361 DYVPGLKVDG MDFLAVKQAC KFAKEHVLEN GPIILEMDTY RYHGHSMSDP GSTYRTRDEI 420 421 AGIRQERDPI ERVRKLLLTH DLATAQELKD MEKEIRKEVD TAIAKAKESP MPDTSELFKN 480 481 VYVNDCGLES FGVDRKVVRT VLP 503
Nucleotide CDS Sequence (FASTA)
1 CGGGCCGAGA TCGCCGCCGA CTCGCTCTAC AAGGCGAAGC TCATCCGGGG CTTCTGCCAC 60 61 CTGTACGACG GCCAGGAGGC GGTCGCCGTG GGCATGGAGG CCGCCATCAC CCGCCGCGAC 120 121 GCCATCATCA CCGCCTACCG CGACCACTGC CTCTACCTCG CGCGCGGCGG GGACCTCGTG 180 181 GCCGCCTTCG CCGAGCTCAT GGGCCGCGTC GACGGATGCT CCAGGGGCAA GGGCGGCTCC 240 241 ATGCACTTCT ACAAGAAGGA CGCCAACTTC TACGGCGGCC ACGGCATCGT CGGCGCGCAG 300 301 GTGCCCCTCG GCTGCGGCCT CGCCTTCGCG CAGAGGTACC GGAAGGAGGG CACCGTCACC 360 361 TTCGACCTCT ACGGCGACGG CGCCGCCAAC CAGGGCCAGC TCTTCGAGGC GCTCAACATG 420 421 GCCGCGCTCT GGAAGCTGCC CGTCATACTC GTCTGCGAGA ACAACCACTA TGGGATGGGG 480 481 ACGGCCGAGT GGAAGGCCTC CAAGAGCCCG GCGTACTACA AGCGCGGGGA CTATGTGCCC 540 541 GGATTGAAGG TTGATGGTAT GGATTTTCTT GCGGTGAAGC AGGCTTGTAA ATTTGCCAAA 600 601 GAACATGTTC TGGAAAATGG ACCGATTATT CTTGAGATGG ACACATACAG ATACCATGGC 660 661 CATTCTATGT CGGATCCAGG CAGCACTTAC CGCACTAGAG ATGAGATTGC GGGAATAAGA 720 721 CAGGTCAACA TGGCTAATAA CACTCTGCTT AAAATTTGTG CTCTACCAAA GACTGACCTT 780 781 CTGAGCTTAG CTGTTTGTCA TGATATAACA GGAGCGTGA 819

▼ KEYWORD

ID	Family
KW-0175	Coiled coil
KW-0181	Complete proteome
KW-0560	Oxidoreductase
KW-0670	Pyruvate
KW-1185	Reference proteome
KW-0786	Thiamine pyrophosphate

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0043231	Cellular Component	Intracellular membrane-bounded organelle
GO:0004739	Molecular Function	Pyruvate dehydrogenase (acetyl-transferring) activity
GO:0006086	Biological Process	Acetyl-CoA biosynthetic process from pyruvate

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Tru-0781	Triticum urartu	99.44	1e-127	377
LLPS-Sob-1486	Sorghum bicolor	91.83	0.0	687
LLPS-Orbr-2205	Oryza brachyantha	91.8	0.0	687
LLPS-Orm-0585	Oryza meridionalis	91.58	0.0	687
LLPS-Ors-2238	Oryza sativa	91.3	0.0	685
LLPS-Ori-0363	Oryza indica	91.3	0.0	685
LLPS-Orr-0889	Oryza rufipogon	90.96	0.0	615
LLPS-Orb-0647	Oryza barthii	90.7	0.0	659
LLPS-Orni-2110	Oryza nivara	90.42	0.0	657
LLPS-Orgl-1763	Oryza glumaepatula	90.42	0.0	660
LLPS-Sei-0325	Setaria italica	89.88	9e-162	468
LLPS-Lep-2180	Leersia perrieri	86.1	0.0	649
LLPS-Zem-2071	Zea mays	85.01	0.0	640
LLPS-Brd-1072	Brachypodium distachyon	85.01	0.0	647
LLPS-Tra-2675	Triticum aestivum	84.51	0.0	642
LLPS-Orp-0849	Oryza punctata	82.83	0.0	603
LLPS-Cus-2149	Cucumis sativus	82.4	0.0	605
LLPS-Phv-0217	Phaseolus vulgaris	82.12	0.0	558
LLPS-Coc-0057	Corchorus capsularis	81.47	0.0	620
LLPS-Nia-2260	Nicotiana attenuata	80.66	0.0	600
LLPS-Mae-2057	Manihot esculenta	80.65	0.0	592
LLPS-Gor-2633	Gossypium raimondii	80.65	0.0	611
LLPS-Via-1760	Vigna angularis	80.4	0.0	573
LLPS-Dac-1792	Daucus carota	80.11	0.0	601
LLPS-Hea-1335	Helianthus annuus	79.95	0.0	603
LLPS-Glm-2588	Glycine max	79.84	0.0	600
LLPS-Brr-0719	Brassica rapa	79.29	0.0	609
LLPS-Brn-3162	Brassica napus	79.29	0.0	609
LLPS-Viv-0174	Vitis vinifera	79.12	0.0	591
LLPS-Bro-0736	Brassica oleracea	79.02	0.0	608
LLPS-Sol-2295	Solanum lycopersicum	79.02	0.0	598
LLPS-Sot-1054	Solanum tuberosum	79.02	0.0	600
LLPS-Pot-2806	Populus trichocarpa	78.75	0.0	583
LLPS-Art-0953	Arabidopsis thaliana	78.75	0.0	607
LLPS-Arl-0506	Arabidopsis lyrata	78.75	0.0	606
LLPS-Met-1625	Medicago truncatula	78.12	0.0	582
LLPS-Mua-0794	Musa acuminata	76.23	4e-171	492
LLPS-Vir-0336	Vigna radiata	71.63	5e-171	496
LLPS-Php-0348	Physcomitrella patens	69.21	0.0	528
LLPS-Sem-1609	Selaginella moellendorffii	66.39	2e-172	499
LLPS-Tag-0857	Taeniopygia guttata	63.37	7e-39	142
LLPS-Chr-0340	Chlamydomonas reinhardtii	59.32	5e-146	432
LLPS-Leo-0830	Lepisosteus oculatus	55.39	1e-117	359
LLPS-Cis-1386	Ciona savignyi	55.02	1e-114	348
LLPS-Pof-0701	Poecilia formosa	54.93	1e-115	353
LLPS-Cae-2028	Caenorhabditis elegans	53.85	8e-114	350
LLPS-Scm-2702	Scophthalmus maximus	53.73	6e-104	325
LLPS-Urm-3344	Ursus maritimus	53.68	6e-110	339
LLPS-Xet-1836	Xenopus tropicalis	53.68	4e-113	348
LLPS-Scf-2665	Scleropages formosus	53.59	1e-116	358
LLPS-Myl-1649	Myotis lucifugus	53.55	6e-113	347
LLPS-Orn-1305	Oreochromis niloticus	53.29	3e-112	345
LLPS-Dar-3426	Danio rerio	53.29	2e-115	353
LLPS-Mum-4676	Mus musculus	53.25	2e-112	345
LLPS-Ova-3461	Ovis aries	53.25	1e-112	346
LLPS-Bot-1071	Bos taurus	53.25	9e-113	346
LLPS-Otg-0683	Otolemur garnettii	53.21	3e-105	326
LLPS-Pat-3430	Pan troglodytes	53.13	7e-112	345
LLPS-Hos-0296	Homo sapiens	53.13	2e-112	345
LLPS-Gog-3678	Gorilla gorilla	53.13	2e-112	345
LLPS-Fec-0524	Felis catus	52.96	5e-112	344
LLPS-Fud-3763	Fukomys damarensis	52.96	3e-112	345
LLPS-Mea-3186	Mesocricetus auratus	52.96	1e-111	343
LLPS-Aim-0286	Ailuropoda melanoleuca	52.96	3e-112	345
LLPS-Ere-0625	Erinaceus europaeus	52.96	4e-104	324
LLPS-Dio-3942	Dipodomys ordii	52.96	8e-112	343
LLPS-Crn-0557	Cryptococcus neoformans	52.92	2e-115	354
LLPS-Pes-2339	Pelodiscus sinensis	52.85	6e-102	318
LLPS-Poa-4210	Pongo abelii	52.84	2e-111	343
LLPS-Orl-0473	Oryzias latipes	52.84	9e-103	323
LLPS-Loa-3946	Loxodonta africana	52.8	7e-111	341
LLPS-Man-3836	Macaca nemestrina	52.66	5e-102	320
LLPS-Pap-3024	Pan paniscus	52.66	2e-101	320
LLPS-Meg-1021	Meleagris gallopavo	52.66	1e-104	325
LLPS-Ict-4504	Ictidomys tridecemlineatus	52.66	2e-111	342
LLPS-Nol-2006	Nomascus leucogenys	52.66	3e-102	320
LLPS-Mam-4296	Macaca mulatta	52.66	3e-102	320
LLPS-Eqc-2160	Equus caballus	52.66	4e-111	342
LLPS-Cap-0691	Cavia porcellus	52.66	1e-111	343
LLPS-Caf-2821	Canis familiaris	52.66	2e-111	342
LLPS-Caj-1340	Callithrix jacchus	52.66	3e-102	320
LLPS-Aon-4581	Aotus nancymaae	52.66	1e-101	319
LLPS-Cea-3575	Cercocebus atys	52.66	3e-102	320
LLPS-Sus-3185	Sus scrofa	52.66	2e-103	322
LLPS-Ora-2673	Ornithorhynchus anatinus	52.66	2e-103	322
LLPS-Maf-0137	Macaca fascicularis	52.66	6e-102	320
LLPS-Mup-3057	Mustela putorius furo	52.66	4e-111	342
LLPS-Ran-0802	Rattus norvegicus	52.66	1e-110	340
LLPS-Asni-1516	Aspergillus niger	52.62	5e-112	345
LLPS-Cii-0064	Ciona intestinalis	52.6	4e-121	367
LLPS-Rhb-2988	Rhinopithecus bieti	52.54	8e-111	341
LLPS-Ast-1231	Aspergillus terreus	52.45	1e-113	349
LLPS-Orc-0567	Oryctolagus cuniculus	52.37	6e-111	341
LLPS-Cas-0515	Carlito syrichta	52.37	2e-101	318
LLPS-Tut-1755	Tursiops truncatus	52.37	3e-111	342
LLPS-Nef-1039	Neosartorya fischeri	52.33	9e-113	347
LLPS-Blg-0670	Blumeria graminis	52.25	1e-107	333
LLPS-Sah-3031	Sarcophilus harrisii	52.07	3e-111	342
LLPS-Aso-0479	Aspergillus oryzae	51.95	2e-108	334
LLPS-Fia-1189	Ficedula albicollis	51.93	2e-102	320
LLPS-Paa-2119	Papio anubis	51.91	7e-111	341
LLPS-Mal-0013	Mandrillus leucophaeus	51.61	4e-110	339
LLPS-Mod-4351	Monodelphis domestica	51.48	3e-111	342
LLPS-Tar-3150	Takifugu rubripes	51.4	1e-106	332
LLPS-Asm-2833	Astyanax mexicanus	51.34	1e-99	312
LLPS-Ten-0221	Tetraodon nigroviridis	51.12	8e-115	352
LLPS-Gaa-2364	Gasterosteus aculeatus	50.97	1e-117	359
LLPS-Xim-0452	Xiphophorus maculatus	50.7	2e-114	353
LLPS-Asf-0825	Aspergillus flavus	50.57	3e-108	335
LLPS-Lac-3750	Latimeria chalumnae	50.14	1e-113	349
LLPS-Anp-1089	Anas platyrhynchos	50.0	6e-106	328
LLPS-Icp-1197	Ictalurus punctatus	49.86	5e-114	350
LLPS-Anc-0122	Anolis carolinensis	49.72	3e-115	352
LLPS-Gaga-3914	Gallus gallus	49.72	1e-104	326
LLPS-Drm-1058	Drosophila melanogaster	49.41	4e-103	324
LLPS-Asfu-0296	Aspergillus fumigatus	45.21	5e-72	239
LLPS-Put-0339	Puccinia triticina	42.64	6e-81	264
LLPS-Asc-0275	Aspergillus clavatus	40.47	6e-67	226
LLPS-Prp-1284	Prunus persica	40.35	1e-72	243
LLPS-Org-1261	Oryza glaberrima	39.82	2e-70	235
LLPS-Thc-2353	Theobroma cacao	38.94	1e-68	235
LLPS-Amt-1386	Amborella trichopoda	37.74	3e-71	239
LLPS-Cym-0832	Cyanidioschyzon merolae	37.03	3e-59	204
LLPS-Chc-1157	Chondrus crispus	36.64	1e-63	217
LLPS-Gas-1278	Galdieria sulphuraria	36.34	1e-55	195
LLPS-Osl-1061	Ostreococcus lucimarinus	35.16	4e-41	157

LLPS-Hov-0115

Protein Sequence

Nucleotide Sequence