• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Tar-3024
ppih

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Peptidyl-prolyl cis-trans isomerase
Gene Name: ppih
Ensembl Gene: ENSTRUG00000015375.2
Ensembl Protein: ENSTRUP00000039289.1
Organism: Takifugu rubripes
Taxa ID: 31033
LLPS Type: Client


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION


PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

▼ CROSS REFERENCE


▼ SEQUENCE


Protein Sequence (FASTA)
1     MSILQSNPSN  PVVFFDITIG  GQDVGRMKIE  LFADVVPKTA  ENFRQFCTGE  FRKDGVPIGY  60
61    KGCTFHRVIK  DFMIQGGDFV  NGDGTGVCSI  YRGPFADENF  TLKHETPGLL  SMANSGPGTN  120
121   GCQFFITCTN  CHWLDAKHVV  FGKVIDGLLI  VRKIENVPVG  PNNKPKLPIV  IAQCGEM  177
Nucleotide CDS Sequence (FASTA)
1     ATGTCCATCC  TGCAGTCAAA  CCCCAGCAAC  CCAGTGGTAT  TCTTCGATAT  TACCATCGGA  60
61    GGACAGGACG  TGGGGCGGAT  GAAGATAGAA  CTGTTTGCTG  ACGTGGTTCC  AAAGACGGCA  120
121   GAGAATTTTC  GGCAGTTCTG  CACAGGGGAG  TTCAGGAAGG  ATGGCGTTCC  TATTGGATAT  180
181   AAAGGTTGCA  CCTTTCACAG  GGTGATAAAA  GACTTTATGA  TCCAAGGAGG  AGATTTTGTA  240
241   AATGGTGACG  GAACTGGAGT  CTGCAGCATT  TACAGGGGTC  CATTTGCAGA  TGAAAACTTC  300
301   ACTCTCAAGC  ATGAAACACC  TGGTCTTCTG  TCCATGGCAA  ACAGCGGTCC  GGGGACAAAC  360
361   GGCTGCCAGT  TCTTCATCAC  CTGCACTAAC  TGTCACTGGT  TGGATGCGAA  GCATGTTGTT  420
421   TTTGGAAAAG  TGATTGACGG  CTTGCTTATT  GTGAGAAAAA  TTGAGAATGT  TCCAGTAGGA  480
481   CCCAACAACA  AACCTAAACT  CCCCATCGTC  ATCGCACAGT  GTGGAGAGAT  GTGA  534

▼ KEYWORD


ID
Family
Complete proteome
Isomerase
Reference proteome
Rotamase

▼ GENE ONTOLOGY


ID
Classification
Description
Molecular Function
Peptidyl-prolyl cis-trans isomerase activity
Biological Process
Angiogenesis
Biological Process
Protein folding

▼ KEGG



▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ten-1541Tetraodon nigroviridis95.484e-122 349
LLPS-Leo-2041Lepisosteus oculatus90.384e-103 301
LLPS-Orl-4090Oryzias latipes89.833e-116 334
LLPS-Icp-1639Ictalurus punctatus89.838e-117 336
LLPS-Xim-3900Xiphophorus maculatus89.832e-117 337
LLPS-Pof-1814Poecilia formosa89.837e-117 336
LLPS-Orn-2626Oreochromis niloticus89.15e-102 297
LLPS-Scf-1739Scleropages formosus88.78e-116 333
LLPS-Eqc-2554Equus caballus88.463e-99 295
LLPS-Tag-3149Taeniopygia guttata88.392e-100 293
LLPS-Pes-2729Pelodiscus sinensis87.423e-97 285
LLPS-Anp-1729Anas platyrhynchos87.315e-85 253
LLPS-Gaa-0648Gasterosteus aculeatus87.12e-99 291
LLPS-Fia-0044Ficedula albicollis87.012e-114 330
LLPS-Gaga-2823Gallus gallus86.442e-114 330
LLPS-Xet-3366Xenopus tropicalis86.444e-113 326
LLPS-Mum-4909Mus musculus85.311e-112 325
LLPS-Maf-3489Macaca fascicularis85.311e-112 325
LLPS-Mea-3732Mesocricetus auratus85.311e-112 325
LLPS-Chs-2765Chlorocebus sabaeus85.311e-112 325
LLPS-Sus-4057Sus scrofa85.311e-112 325
LLPS-Cea-0733Cercocebus atys85.311e-112 325
LLPS-Aon-1019Aotus nancymaae85.311e-112 325
LLPS-Gog-0249Gorilla gorilla85.311e-112 325
LLPS-Caj-4638Callithrix jacchus85.311e-112 325
LLPS-Tut-0054Tursiops truncatus85.311e-112 325
LLPS-Dio-4388Dipodomys ordii85.311e-112 325
LLPS-Paa-3834Papio anubis85.311e-112 325
LLPS-Mal-4203Mandrillus leucophaeus85.311e-112 325
LLPS-Ova-0469Ovis aries85.311e-112 325
LLPS-Mup-3004Mustela putorius furo85.311e-112 325
LLPS-Aim-1869Ailuropoda melanoleuca85.311e-112 325
LLPS-Hos-0035Homo sapiens85.311e-112 325
LLPS-Urm-3010Ursus maritimus85.311e-112 325
LLPS-Pap-2401Pan paniscus85.311e-112 325
LLPS-Pat-1483Pan troglodytes85.311e-112 325
LLPS-Fec-0939Felis catus85.311e-112 325
LLPS-Man-2158Macaca nemestrina85.311e-112 325
LLPS-Loa-1513Loxodonta africana85.311e-112 325
LLPS-Otg-0721Otolemur garnettii85.311e-112 325
LLPS-Orc-4221Oryctolagus cuniculus85.311e-112 325
LLPS-Rhb-1727Rhinopithecus bieti85.311e-112 325
LLPS-Caf-1591Canis familiaris85.311e-112 325
LLPS-Poa-4258Pongo abelii85.311e-112 325
LLPS-Cap-2230Cavia porcellus85.311e-112 325
LLPS-Mam-2863Macaca mulatta85.311e-112 325
LLPS-Cas-4035Carlito syrichta85.311e-112 325
LLPS-Ict-3842Ictidomys tridecemlineatus85.311e-112 325
LLPS-Fud-2490Fukomys damarensis85.167e-97 285
LLPS-Lac-3406Latimeria chalumnae84.83e-108 314
LLPS-Ran-4535Rattus norvegicus84.755e-110 318
LLPS-Scm-3804Scophthalmus maximus84.751e-109 318
LLPS-Nol-4481Nomascus leucogenys84.753e-110 319
LLPS-Ere-0931Erinaceus europaeus84.663e-109 317
LLPS-Mod-1965Monodelphis domestica84.184e-112 324
LLPS-Ora-1235Ornithorhynchus anatinus82.865e-61 191
LLPS-Myl-2944Myotis lucifugus81.461e-105 307
LLPS-Dar-2876Danio rerio79.892e-110 320
LLPS-Drm-1431Drosophila melanogaster76.142e-95 281
LLPS-Met-0140Medicago truncatula75.03e-91 271
LLPS-Cus-1494Cucumis sativus75.02e-91 272
LLPS-Glm-2280Glycine max74.424e-90 268
LLPS-Viv-1787Vitis vinifera74.422e-91 271
LLPS-Gor-0942Gossypium raimondii74.426e-91 270
LLPS-Mae-2282Manihot esculenta74.422e-90 270
LLPS-Phv-1524Phaseolus vulgaris74.426e-91 271
LLPS-Prp-1185Prunus persica74.425e-90 268
LLPS-Sem-1622Selaginella moellendorffii73.998e-89 265
LLPS-Hea-2174Helianthus annuus73.846e-91 270
LLPS-Sol-0600Solanum lycopersicum73.684e-88 263
LLPS-Sot-2180Solanum tuberosum73.683e-88 263
LLPS-Nia-1205Nicotiana attenuata73.538e-87 260
LLPS-Asm-3531Astyanax mexicanus73.457e-89 264
LLPS-Brn-2458Brassica napus73.269e-89 265
LLPS-Brr-1885Brassica rapa73.264e-89 266
LLPS-Gas-1080Galdieria sulphuraria73.033e-93 276
LLPS-Orb-1878Oryza barthii72.672e-86 259
LLPS-Orni-1307Oryza nivara72.673e-87 261
LLPS-Orgl-2293Oryza glumaepatula72.672e-86 259
LLPS-Ors-2038Oryza sativa72.672e-86 259
LLPS-Orp-0958Oryza punctata72.676e-86 258
LLPS-Pot-0230Populus trichocarpa72.673e-90 268
LLPS-Orbr-0050Oryza brachyantha72.678e-87 260
LLPS-Orm-1283Oryza meridionalis72.673e-87 261
LLPS-Bro-2020Brassica oleracea72.673e-88 264
LLPS-Php-0190Physcomitrella patens72.092e-85 257
LLPS-Hov-1420Hordeum vulgare72.091e-87 263
LLPS-Sei-1820Setaria italica72.092e-86 266
LLPS-Tra-2086Triticum aestivum72.097e-88 263
LLPS-Arl-2197Arabidopsis lyrata72.092e-88 264
LLPS-Art-2319Arabidopsis thaliana72.091e-88 265
LLPS-Lep-2049Leersia perrieri71.595e-85 265
LLPS-Sob-1317Sorghum bicolor71.514e-85 256
LLPS-Zem-1210Zea mays71.432e-66 212
LLPS-Cae-1141Caenorhabditis elegans71.351e-87 262
LLPS-Tru-2114Triticum urartu71.336e-75 228
LLPS-Mua-2500Musa acuminata70.931e-87 263
LLPS-Brd-1217Brachypodium distachyon70.938e-86 258
LLPS-Cii-1719Ciona intestinalis70.628e-93 275
LLPS-Cis-0000Ciona savignyi70.522e-90 268
LLPS-Osl-1435Ostreococcus lucimarinus70.181e-82 249
LLPS-Usm-0242Ustilago maydis70.137e-76 231
LLPS-Chr-1024Chlamydomonas reinhardtii70.061e-84 254
LLPS-Coc-1585Corchorus capsularis69.778e-82 247
LLPS-Mel-0910Melampsora laricipopulina68.95e-77 236
LLPS-Crn-1486Cryptococcus neoformans68.641e-79 241
LLPS-Pug-1426Puccinia graminis68.641e-80 244
LLPS-Put-0612Puccinia triticina68.641e-80 244
LLPS-Spr-1566Sporisorium reilianum68.262e-81 246
LLPS-Dos-1014Dothistroma septosporum67.251e-76 233
LLPS-Scs-1129Sclerotinia sclerotiorum67.067e-75 229
LLPS-Nef-0900Neosartorya fischeri66.892e-63 199
LLPS-Asfu-1659Aspergillus fumigatus66.895e-64 201
LLPS-Ast-0926Aspergillus terreus66.675e-74 227
LLPS-Asni-0281Aspergillus niger66.478e-74 226
LLPS-Pytr-0975Pyrenophora triticirepentis66.095e-70 217
LLPS-Blg-0382Blumeria graminis65.76e-71 219
LLPS-Scc-1624Schizosaccharomyces cryophilus65.51e-73 226
LLPS-Orr-2048Oryza rufipogon65.451e-82 250
LLPS-Aso-0927Aspergillus oryzae65.299e-73 224
LLPS-Asf-1464Aspergillus flavus65.299e-73 224
LLPS-Nec-0972Neurospora crassa65.122e-71 221
LLPS-Pyt-1025Pyrenophora teres64.943e-69 215
LLPS-Asc-0818Aspergillus clavatus64.95e-62 195
LLPS-Miv-0851Microbotryum violaceum64.772e-78 241
LLPS-Mao-0246Magnaporthe oryzae64.535e-70 217
LLPS-Fus-0830Fusarium solani64.532e-68 213
LLPS-Coo-1533Colletotrichum orbiculare63.955e-69 214
LLPS-Beb-0049Beauveria bassiana63.951e-69 216
LLPS-Gag-0966Gaeumannomyces graminis63.924e-64 202
LLPS-Zyt-1549Zymoseptoria tritici63.539e-69 213
LLPS-Map-0665Magnaporthe poae63.371e-70 218
LLPS-Cogr-1062Colletotrichum graminicola63.371e-67 211
LLPS-Lem-1122Leptosphaeria maculans63.096e-60 191
LLPS-Scp-1616Schizosaccharomyces pombe62.571e-70 218
LLPS-Trr-1587Trichoderma reesei62.214e-66 207
LLPS-Ved-0640Verticillium dahliae61.994e-68 212
LLPS-Chc-1182Chondrus crispus61.673e-78 238
LLPS-Fuv-1587Fusarium verticillioides61.631e-67 211
LLPS-Trv-0692Trichoderma virens61.633e-66 207
LLPS-Fuo-0296Fusarium oxysporum61.632e-67 210
LLPS-Abg-1657Absidia glauca60.619e-62 198
LLPS-Tum-0696Tuber melanosporum60.343e-69 214
LLPS-Dac-1303Daucus carota58.827e-64 201
LLPS-Via-1475Vigna angularis58.826e-64 201
LLPS-Vir-0950Vigna radiata58.824e-64 201
LLPS-Thc-1933Theobroma cacao58.484e-61 194
LLPS-Phn-1567Phaeosphaeria nodorum58.12e-62 197
LLPS-Ori-1838Oryza indica57.652e-60 192
LLPS-Org-1037Oryza glaberrima57.652e-60 192