• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-4388
Ppih

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Peptidyl-prolyl cis-trans isomerase
Gene Name: Ppih
Ensembl Gene: ENSDORG00000016152.2
Ensembl Protein: ENSDORP00000015193.2
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAVANSSPVN  PVVFFDVSIG  GQEVGRMKIE  LFADVVPKTA  ENFRQFCTGE  FRKDGVPIGY  60
61    KGSTFHRVIK  DFMIQGGDFV  NGDGTGVASI  YRGPFADENF  KLRHSAPGLL  SMANSGPSTN  120
121   GCQFFITCSK  CDWLDGKHVV  FGKIIDGLLV  MRKIENVPTG  PNNKPKLPVV  ISQCGEM  177
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGTGG  CAAATTCAAG  CCCCGTCAAC  CCCGTCGTGT  TCTTTGATGT  TAGCATTGGT  60
61    GGTCAGGAGG  TTGGACGCAT  GAAGATTGAG  CTGTTTGCAG  ACGTTGTGCC  TAAGACGGCC  120
121   GAGAACTTTA  GGCAGTTCTG  CACTGGAGAA  TTCAGAAAAG  ATGGGGTTCC  AATAGGATAC  180
181   AAAGGGAGCA  CTTTCCATAG  GGTCATAAAG  GATTTCATGA  TTCAGGGTGG  AGATTTTGTT  240
241   AATGGAGATG  GTACAGGAGT  TGCCAGTATT  TACCGGGGGC  CATTTGCAGA  TGAAAATTTC  300
301   AAACTTAGAC  ACTCTGCTCC  AGGCCTACTT  TCTATGGCAA  ACAGTGGTCC  CAGTACAAAT  360
361   GGCTGTCAGT  TCTTCATCAC  CTGCTCTAAA  TGTGATTGGC  TGGATGGGAA  GCATGTGGTG  420
421   TTTGGTAAGT  CCTACTCCTT  TCTTATTTTC  CAGAATGTTC  CCACAGGCCC  CAACAATAAG  480
481   CCCAAGTTGC  CTGTGGTAAT  CTCACAGTGT  GGGGAGATGT  AG  522

▼ KEYWORD

ID
Family
Complete proteome
Isomerase
Reference proteome
Rotamase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Peptidyl-prolyl cis-trans isomerase activity
Biological Process
Protein folding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Loa-1513Loxodonta africana100.08e-128 363
LLPS-Man-2158Macaca nemestrina100.08e-128 363
LLPS-Fec-0939Felis catus100.08e-128 363
LLPS-Urm-3010Ursus maritimus100.08e-128 363
LLPS-Pap-2401Pan paniscus100.08e-128 363
LLPS-Pat-1483Pan troglodytes100.08e-128 363
LLPS-Hos-0035Homo sapiens100.08e-128 363
LLPS-Rhb-1727Rhinopithecus bieti100.08e-128 363
LLPS-Orc-4221Oryctolagus cuniculus100.08e-128 363
LLPS-Otg-0721Otolemur garnettii100.08e-128 363
LLPS-Mam-2863Macaca mulatta100.08e-128 363
LLPS-Cap-2230Cavia porcellus100.08e-128 363
LLPS-Caf-1591Canis familiaris100.08e-128 363
LLPS-Poa-4258Pongo abelii100.08e-128 363
LLPS-Ict-3842Ictidomys tridecemlineatus100.08e-128 363
LLPS-Cas-4035Carlito syrichta100.08e-128 363
LLPS-Cea-0733Cercocebus atys100.08e-128 363
LLPS-Aon-1019Aotus nancymaae100.08e-128 363
LLPS-Sus-4057Sus scrofa100.08e-128 363
LLPS-Chs-2765Chlorocebus sabaeus100.08e-128 363
LLPS-Mea-3732Mesocricetus auratus100.08e-128 363
LLPS-Mum-4909Mus musculus100.08e-128 363
LLPS-Maf-3489Macaca fascicularis100.08e-128 363
LLPS-Caj-4638Callithrix jacchus100.08e-128 363
LLPS-Fud-2490Fukomys damarensis100.01e-110 320
LLPS-Gog-0249Gorilla gorilla100.08e-128 363
LLPS-Tut-0054Tursiops truncatus100.08e-128 363
LLPS-Ova-0469Ovis aries100.08e-128 363
LLPS-Mup-3004Mustela putorius furo100.08e-128 363
LLPS-Aim-1869Ailuropoda melanoleuca100.08e-128 363
LLPS-Paa-3834Papio anubis100.08e-128 363
LLPS-Mal-4203Mandrillus leucophaeus100.08e-128 363
LLPS-Nol-4481Nomascus leucogenys99.443e-125 357
LLPS-Ran-4535Rattus norvegicus99.444e-125 357
LLPS-Ere-0931Erinaceus europaeus99.432e-124 355
LLPS-Mod-1965Monodelphis domestica98.872e-127 362
LLPS-Tag-3149Taeniopygia guttata98.711e-110 319
LLPS-Pes-2729Pelodiscus sinensis98.688e-108 312
LLPS-Anp-1729Anas platyrhynchos98.511e-94 278
LLPS-Ora-1235Ornithorhynchus anatinus98.19e-71 216
LLPS-Eqc-2554Equus caballus96.343e-110 323
LLPS-Gaga-2823Gallus gallus95.489e-123 351
LLPS-Fia-0044Ficedula albicollis94.358e-122 348
LLPS-Myl-2944Myotis lucifugus93.821e-119 343
LLPS-Leo-2041Lepisosteus oculatus92.951e-107 312
LLPS-Xet-3366Xenopus tropicalis91.537e-119 341
LLPS-Lac-3406Latimeria chalumnae91.236e-115 331
LLPS-Scf-1739Scleropages formosus89.836e-117 336
LLPS-Orn-2626Oreochromis niloticus89.11e-103 301
LLPS-Icp-1639Ictalurus punctatus88.74e-116 334
LLPS-Pof-1814Poecilia formosa87.018e-116 333
LLPS-Orl-4090Oryzias latipes87.012e-115 332
LLPS-Xim-3900Xiphophorus maculatus87.012e-116 334
LLPS-Tar-3024Takifugu rubripes85.311e-112 325
LLPS-Gaa-0648Gasterosteus aculeatus84.522e-98 288
LLPS-Ten-1541Tetraodon nigroviridis84.185e-111 321
LLPS-Scm-3804Scophthalmus maximus83.056e-109 315
LLPS-Dar-2876Danio rerio82.012e-112 325
LLPS-Drm-1431Drosophila melanogaster78.362e-99 291
LLPS-Asm-3531Astyanax mexicanus75.711e-91 271
LLPS-Cii-1719Ciona intestinalis75.158e-95 280
LLPS-Cis-0000Ciona savignyi74.561e-94 279
LLPS-Gas-1080Galdieria sulphuraria74.431e-95 282
LLPS-Met-0140Medicago truncatula73.846e-92 273
LLPS-Php-0190Physcomitrella patens73.372e-88 264
LLPS-Art-2319Arabidopsis thaliana73.265e-90 268
LLPS-Brr-1885Brassica rapa73.264e-89 266
LLPS-Prp-1185Prunus persica73.263e-91 271
LLPS-Brn-2458Brassica napus73.268e-89 266
LLPS-Arl-2197Arabidopsis lyrata73.269e-90 268
LLPS-Cus-1494Cucumis sativus73.265e-91 271
LLPS-Sem-1622Selaginella moellendorffii72.839e-90 267
LLPS-Phv-1524Phaseolus vulgaris72.675e-91 271
LLPS-Orbr-0050Oryza brachyantha72.671e-87 262
LLPS-Bro-2020Brassica oleracea72.672e-88 264
LLPS-Glm-2280Glycine max72.673e-90 269
LLPS-Hea-2174Helianthus annuus72.673e-92 274
LLPS-Lep-2049Leersia perrieri72.675e-85 265
LLPS-Viv-1787Vitis vinifera72.092e-90 269
LLPS-Mae-2282Manihot esculenta72.097e-91 270
LLPS-Tra-2086Triticum aestivum72.091e-88 265
LLPS-Sei-1820Setaria italica72.092e-87 268
LLPS-Hov-1420Hordeum vulgare72.092e-88 264
LLPS-Tru-2114Triticum urartu72.07e-77 233
LLPS-Orp-0958Oryza punctata71.514e-86 259
LLPS-Pot-0230Populus trichocarpa71.511e-90 270
LLPS-Gor-0942Gossypium raimondii71.512e-90 269
LLPS-Ors-2038Oryza sativa71.519e-87 260
LLPS-Sob-1317Sorghum bicolor71.512e-86 259
LLPS-Orm-1283Oryza meridionalis71.513e-87 261
LLPS-Orb-1878Oryza barthii71.519e-87 260
LLPS-Orni-1307Oryza nivara71.513e-87 261
LLPS-Orgl-2293Oryza glumaepatula71.519e-87 260
LLPS-Sol-0600Solanum lycopersicum71.353e-87 261
LLPS-Sot-2180Solanum tuberosum71.353e-87 261
LLPS-Osl-1435Ostreococcus lucimarinus71.187e-84 252
LLPS-Pug-1426Puccinia graminis71.019e-86 257
LLPS-Nia-1205Nicotiana attenuata71.011e-86 259
LLPS-Put-0612Puccinia triticina71.019e-86 257
LLPS-Mua-2500Musa acuminata70.935e-89 266
LLPS-Brd-1217Brachypodium distachyon70.932e-86 259
LLPS-Zem-1210Zea mays70.712e-66 212
LLPS-Cae-1141Caenorhabditis elegans70.598e-89 265
LLPS-Usm-0242Ustilago maydis70.132e-77 235
LLPS-Mel-0910Melampsora laricipopulina69.517e-80 243
LLPS-Crn-1486Cryptococcus neoformans68.646e-83 249
LLPS-Chr-1024Chlamydomonas reinhardtii68.392e-84 254
LLPS-Spr-1566Sporisorium reilianum68.261e-83 252
LLPS-Miv-0851Microbotryum violaceum67.431e-81 249
LLPS-Dos-1014Dothistroma septosporum67.243e-78 238
LLPS-Coc-1585Corchorus capsularis66.866e-81 244
LLPS-Scs-1129Sclerotinia sclerotiorum66.475e-76 232
LLPS-Asni-0281Aspergillus niger65.887e-74 227
LLPS-Blg-0382Blumeria graminis65.75e-73 224
LLPS-Nef-0900Neosartorya fischeri65.565e-63 198
LLPS-Asfu-1659Aspergillus fumigatus65.561e-63 199
LLPS-Scc-1624Schizosaccharomyces cryophilus65.096e-74 226
LLPS-Chc-1182Chondrus crispus65.01e-83 252
LLPS-Gag-0966Gaeumannomyces graminis64.565e-65 204
LLPS-Orr-2048Oryza rufipogon64.41e-82 251
LLPS-Aso-0927Aspergillus oryzae64.121e-72 224
LLPS-Asf-1464Aspergillus flavus64.121e-72 224
LLPS-Map-0665Magnaporthe poae63.955e-72 222
LLPS-Nec-0972Neurospora crassa63.951e-71 221
LLPS-Lem-1448Leptosphaeria maculans63.915e-63 200
LLPS-Beb-0049Beauveria bassiana63.583e-70 217
LLPS-Ast-0926Aspergillus terreus63.531e-71 221
LLPS-Mao-0246Magnaporthe oryzae63.373e-70 218
LLPS-Fus-0830Fusarium solani62.796e-68 211
LLPS-Coo-1533Colletotrichum orbiculare62.791e-68 213
LLPS-Thc-1649Theobroma cacao62.297e-63 211
LLPS-Trr-1587Trichoderma reesei61.638e-67 209
LLPS-Zyt-1549Zymoseptoria tritici61.453e-70 217
LLPS-Ved-0640Verticillium dahliae61.46e-69 214
LLPS-Scp-1616Schizosaccharomyces pombe61.44e-71 219
LLPS-Tum-0696Tuber melanosporum61.181e-67 211
LLPS-Fuo-0296Fusarium oxysporum61.051e-67 211
LLPS-Trv-0692Trichoderma virens61.055e-67 209
LLPS-Cogr-1062Colletotrichum graminicola61.053e-67 210
LLPS-Fuv-1587Fusarium verticillioides61.051e-67 211
LLPS-Pyt-1025Pyrenophora teres60.774e-69 214
LLPS-Pytr-0975Pyrenophora triticirepentis60.225e-70 217
LLPS-Via-0507Vigna angularis59.413e-66 207
LLPS-Abg-1657Absidia glauca59.396e-64 204
LLPS-Org-1037Oryza glaberrima58.824e-65 204
LLPS-Ori-1838Oryza indica58.824e-65 204
LLPS-Dac-1303Daucus carota58.248e-66 206
LLPS-Vir-0950Vigna radiata57.657e-65 203
LLPS-Phn-0241Phaeosphaeria nodorum57.062e-62 197