• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pug-1426
PGTG_19735

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Peptidyl-prolyl cis-trans isomerase
Gene Name: PGTG_19735
Ensembl Gene: PGTG_19735
Ensembl Protein: EFP93963
Organism: Puccinia graminis
Taxa ID: 418459
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEFP93963EFP93963
UniProtE3LBN8, E3LBN8_PUCGT
GeneBankDS178422EFP93963.2
RefSeqXM_003338334.2XP_003338382.2

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAKNANPVPG  AGTNGRPIVF  MDINIGETPA  GRIKFELFTD  IVPKTAENFR  QLCTGEHRPN  60
61    RQPVGYKHSI  FHRVIKDFMV  QGGDFLNSDG  TGSTSIYGQK  FEDENFKLKH  ESAGLLSMAN  120
121   SGPNTNGCQF  FITSAACDFL  DGKHVVFGKV  LDSDGLLVMR  KIENVPTGPN  NRPKLTVKVT  180
181   ECGEM  185
Nucleotide CDS Sequence (FASTA)
1     ATGGCCAAGA  ATGCGAATCC  GGTTCCAGGA  GCGGGAACTA  ATGGTAGACC  GATAGTCTTC  60
61    ATGGATATTA  ATATCGGGGA  AACCCCAGCT  GGACGAATCA  AGTTCGAATT  ATTCACGGAT  120
121   ATCGTCCCCA  AGACAGCCGA  AAACTTTCGA  CAACTTTGTA  CGGGCGAACA  TCGGCCCAAT  180
181   CGACAACCAG  TGGGTTATAA  ACACAGCATC  TTCCATCGTG  TCATCAAAGA  CTTTATGGTC  240
241   CAGGGTGGCG  ATTTCTTGAA  CTCGGATGGG  ACTGGCTCAA  CCTCTATCTA  CGGCCAAAAG  300
301   TTCGAAGACG  AAAACTTCAA  ACTTAAGCAC  GAATCCGCTG  GGCTACTGTC  GATGGCGAAC  360
361   TCGGGGCCAA  ACACGAATGG  ATGTCAATTC  TTTATTACCT  CAGCAGCATG  TGATTTCCTG  420
421   GATGGAAAAC  ACGTCGTCTT  TGGCAAAGTA  TTAGATTCCG  ATGGACTGTT  GGTCATGCGG  480
481   AAGATTGAGA  ACGTGCCCAC  GGGGCCGAAT  AACCGGCCTA  AACTGACCGT  CAAGGTCACT  540
541   GAATGCGGCG  AAATGTAG  558

▼ KEYWORD

ID
Family
Complete proteome
Isomerase
Reference proteome
Rotamase

▼ GENE ONTOLOGY

ID
Classification
Description
Molecular Function
Cyclosporin A binding
Molecular Function
Peptidyl-prolyl cis-trans isomerase activity
Molecular Function
Unfolded protein binding
Biological Process
Protein refolding

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Put-0612Puccinia triticina100.05e-135 382
LLPS-Mel-0910Melampsora laricipopulina93.487e-123 353
LLPS-Spr-1566Sporisorium reilianum76.81e-101 298
LLPS-Usm-0242Ustilago maydis76.582e-86 258
LLPS-Miv-0851Microbotryum violaceum76.475e-94 281
LLPS-Arl-2197Arabidopsis lyrata75.151e-88 265
LLPS-Crn-1486Cryptococcus neoformans74.587e-90 268
LLPS-Hea-2174Helianthus annuus74.569e-86 258
LLPS-Art-2319Arabidopsis thaliana74.564e-87 261
LLPS-Mae-2282Manihot esculenta74.562e-86 259
LLPS-Leo-2041Lepisosteus oculatus73.722e-79 241
LLPS-Tag-3149Taeniopygia guttata73.728e-81 244
LLPS-Eqc-2554Equus caballus73.552e-79 245
LLPS-Anp-1729Anas platyrhynchos73.532e-68 211
LLPS-Sei-1820Setaria italica73.371e-84 261
LLPS-Gor-0942Gossypium raimondii73.376e-85 256
LLPS-Cus-1494Cucumis sativus72.786e-85 256
LLPS-Mua-2500Musa acuminata72.783e-85 257
LLPS-Pot-0230Populus trichocarpa72.789e-85 255
LLPS-Orbr-0050Oryza brachyantha72.787e-85 256
LLPS-Pes-2729Pelodiscus sinensis72.553e-78 237
LLPS-Glm-2280Glycine max72.195e-84 253
LLPS-Php-0190Physcomitrella patens72.194e-85 256
LLPS-Viv-1787Vitis vinifera72.193e-84 253
LLPS-Mod-1965Monodelphis domestica72.194e-86 258
LLPS-Sob-1317Sorghum bicolor72.198e-84 253
LLPS-Phv-1524Phaseolus vulgaris72.199e-85 255
LLPS-Orn-2626Oreochromis niloticus71.791e-78 238
LLPS-Drm-1431Drosophila melanogaster71.64e-86 258
LLPS-Met-0140Medicago truncatula71.61e-84 254
LLPS-Brd-1217Brachypodium distachyon71.69e-85 255
LLPS-Sem-1622Selaginella moellendorffii71.63e-83 251
LLPS-Prp-1185Prunus persica71.63e-84 254
LLPS-Gaga-2823Gallus gallus71.61e-85 257
LLPS-Fia-0044Ficedula albicollis71.68e-86 257
LLPS-Xet-3366Xenopus tropicalis71.355e-86 258
LLPS-Zem-1210Zea mays71.321e-62 202
LLPS-Xim-3900Xiphophorus maculatus71.011e-83 252
LLPS-Tut-0054Tursiops truncatus71.019e-86 257
LLPS-Dio-4388Dipodomys ordii71.019e-86 257
LLPS-Scf-1739Scleropages formosus71.017e-84 252
LLPS-Paa-3834Papio anubis71.019e-86 257
LLPS-Mal-4203Mandrillus leucophaeus71.019e-86 257
LLPS-Mup-3004Mustela putorius furo71.019e-86 257
LLPS-Aim-1869Ailuropoda melanoleuca71.019e-86 257
LLPS-Ova-0469Ovis aries71.019e-86 257
LLPS-Maf-3489Macaca fascicularis71.019e-86 257
LLPS-Mum-4909Mus musculus71.019e-86 257
LLPS-Mea-3732Mesocricetus auratus71.019e-86 257
LLPS-Chs-2765Chlorocebus sabaeus71.019e-86 257
LLPS-Brn-2458Brassica napus71.012e-84 254
LLPS-Sus-4057Sus scrofa71.019e-86 257
LLPS-Cea-0733Cercocebus atys71.019e-86 257
LLPS-Aon-1019Aotus nancymaae71.019e-86 257
LLPS-Gog-0249Gorilla gorilla71.019e-86 257
LLPS-Caj-4638Callithrix jacchus71.019e-86 257
LLPS-Poa-4258Pongo abelii71.019e-86 257
LLPS-Caf-1591Canis familiaris71.019e-86 257
LLPS-Cap-2230Cavia porcellus71.019e-86 257
LLPS-Mam-2863Macaca mulatta71.019e-86 257
LLPS-Cas-4035Carlito syrichta71.019e-86 257
LLPS-Ict-3842Ictidomys tridecemlineatus71.019e-86 257
LLPS-Hos-0035Homo sapiens71.019e-86 257
LLPS-Pat-1483Pan troglodytes71.019e-86 257
LLPS-Urm-3010Ursus maritimus71.019e-86 257
LLPS-Pap-2401Pan paniscus71.019e-86 257
LLPS-Scm-3804Scophthalmus maximus71.011e-81 246
LLPS-Fec-0939Felis catus71.019e-86 257
LLPS-Brr-1885Brassica rapa71.013e-84 254
LLPS-Man-2158Macaca nemestrina71.019e-86 257
LLPS-Loa-1513Loxodonta africana71.019e-86 257
LLPS-Otg-0721Otolemur garnettii71.019e-86 257
LLPS-Orc-4221Oryctolagus cuniculus71.019e-86 257
LLPS-Nia-1205Nicotiana attenuata71.012e-83 251
LLPS-Rhb-1727Rhinopithecus bieti71.019e-86 257
LLPS-Ere-0931Erinaceus europaeus70.831e-82 249
LLPS-Orgl-2293Oryza glumaepatula70.412e-82 249
LLPS-Ran-4535Rattus norvegicus70.415e-83 250
LLPS-Cii-1719Ciona intestinalis70.413e-82 248
LLPS-Orl-4090Oryzias latipes70.412e-82 249
LLPS-Orb-1878Oryza barthii70.412e-82 249
LLPS-Orni-1307Oryza nivara70.415e-83 251
LLPS-Icp-1639Ictalurus punctatus70.414e-83 250
LLPS-Coc-1585Corchorus capsularis70.413e-77 236
LLPS-Orm-1283Oryza meridionalis70.415e-83 251
LLPS-Bro-2020Brassica oleracea70.412e-83 252
LLPS-Nol-4481Nomascus leucogenys70.413e-83 251
LLPS-Pof-1814Poecilia formosa70.415e-83 250
LLPS-Ors-2038Oryza sativa70.412e-82 249
LLPS-Gaa-0648Gasterosteus aculeatus70.077e-69 213
LLPS-Lep-2049Leersia perrieri69.826e-80 252
LLPS-Tra-2086Triticum aestivum69.824e-82 248
LLPS-Sol-0600Solanum lycopersicum69.825e-82 248
LLPS-Cis-0000Ciona savignyi69.822e-80 243
LLPS-Ten-1541Tetraodon nigroviridis69.823e-82 248
LLPS-Tru-2114Triticum urartu69.332e-70 217
LLPS-Sot-2180Solanum tuberosum69.232e-81 247
LLPS-Hov-1420Hordeum vulgare69.231e-81 248
LLPS-Lac-3406Latimeria chalumnae69.234e-81 245
LLPS-Orp-0958Oryza punctata69.235e-81 246
LLPS-Tar-3024Takifugu rubripes68.641e-80 244
LLPS-Chr-1024Chlamydomonas reinhardtii68.245e-80 243
LLPS-Gas-1080Galdieria sulphuraria66.867e-78 238
LLPS-Myl-2944Myotis lucifugus66.867e-79 239
LLPS-Dar-2876Danio rerio66.858e-80 242
LLPS-Blg-0382Blumeria graminis65.918e-70 217
LLPS-Scs-1129Sclerotinia sclerotiorum64.949e-72 221
LLPS-Fud-2490Fukomys damarensis64.634e-72 223
LLPS-Gag-0966Gaeumannomyces graminis64.61e-63 201
LLPS-Cae-1141Caenorhabditis elegans64.51e-75 231
LLPS-Nef-0900Neosartorya fischeri64.473e-61 194
LLPS-Asfu-1659Aspergillus fumigatus63.823e-61 194
LLPS-Map-0665Magnaporthe poae63.647e-69 214
LLPS-Mao-0246Magnaporthe oryzae63.648e-68 211
LLPS-Orr-2048Oryza rufipogon63.33e-78 239
LLPS-Scc-1624Schizosaccharomyces cryophilus63.221e-74 229
LLPS-Asni-0281Aspergillus niger63.168e-69 214
LLPS-Nec-0972Neurospora crassa63.074e-69 215
LLPS-Beb-0049Beauveria bassiana63.074e-70 218
LLPS-Fus-0830Fusarium solani63.076e-68 212
LLPS-Aso-0927Aspergillus oryzae62.572e-68 213
LLPS-Asf-1464Aspergillus flavus62.572e-68 213
LLPS-Chc-1182Chondrus crispus62.571e-76 234
LLPS-Dos-1014Dothistroma septosporum62.574e-66 207
LLPS-Osl-1435Ostreococcus lucimarinus61.931e-74 229
LLPS-Trr-1587Trichoderma reesei61.931e-67 211
LLPS-Zyt-1549Zymoseptoria tritici61.582e-64 202
LLPS-Ast-0926Aspergillus terreus61.585e-68 212
LLPS-Fuv-1587Fusarium verticillioides61.367e-68 212
LLPS-Fuo-0296Fusarium oxysporum61.369e-68 211
LLPS-Coo-1533Colletotrichum orbiculare60.89e-66 206
LLPS-Trv-0692Trichoderma virens60.81e-66 209
LLPS-Asc-0818Aspergillus clavatus60.533e-57 183
LLPS-Asm-3531Astyanax mexicanus60.363e-62 196
LLPS-Cogr-1062Colletotrichum graminicola60.232e-66 208
LLPS-Scp-1616Schizosaccharomyces pombe59.884e-69 214
LLPS-Pytr-0447Pyrenophora triticirepentis59.888e-63 200
LLPS-Ved-0640Verticillium dahliae59.436e-66 207
LLPS-Pyt-1025Pyrenophora teres59.221e-62 198
LLPS-Bot-2886Bos taurus58.332e-57 189
LLPS-Tum-0696Tuber melanosporum57.894e-62 197
LLPS-Asn-1099Aspergillus nidulans57.491e-58 189
LLPS-Abg-0987Absidia glauca56.85e-59 188
LLPS-Phn-0241Phaeosphaeria nodorum56.143e-58 187
LLPS-Vir-0950Vigna radiata56.073e-58 187
LLPS-Via-2009Vigna angularis55.926e-72 224
LLPS-Dac-1303Daucus carota55.887e-58 186
LLPS-Cog-0486Colletotrichum gloeosporioides55.695e-58 189
LLPS-Ori-1838Oryza indica55.563e-57 184
LLPS-Org-1037Oryza glaberrima55.563e-57 184
LLPS-Anc-0740Anolis carolinensis55.033e-57 185