LLPS-Sus-4652
PMM2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Phosphomannomutase |
| Gene Name: | PMM2 |
| Ensembl Gene: | ENSSSCG00000021236.2 |
| Ensembl Protein: | ENSSSCP00000024680.2 |
| Organism: | Sus scrofa |
| Taxa ID: | 9823 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSSSCT00000023055.2 | ENSSSCP00000024680.2 |
| UniProt | F1RKY8, F1RKY8_PIG | |
| GeneBank | AEMK02000018 | |
| RefSeq | XM_005662150.2 | XP_005662207.2 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAPGPALCL FDVDGTLTAP RQKITEDMDC FLQELRQKIK IGVVGGSDFE KVQEQLGNDV 60 61 VEKYDYVFPE NGLVAYKDGK LVSKQNIQGH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI 120 121 EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVED LRQEFAGKGL TFSIGGQISF 180 181 DVFPDGWDKR YCLGHVEKDG YKTIYFFGDK TMPGGNDHEI FEDPRTVSYT VTAPEDTRRI 240 241 CQELFC 246 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTGCTC CCGGCCCAGC GCTCTGCCTC TTCGACGTGG ACGGGACTCT GACCGCTCCC 60 61 AGGCAGAAAA TTACCGAAGA CATGGATTGC TTTCTACAAG AACTGAGGCA GAAGATCAAA 120 121 ATTGGCGTCG TGGGCGGGTC GGACTTTGAG AAAGTACAAG AGCAACTGGG AAACGACGTG 180 181 GTTGAAAAAT ACGATTACGT GTTTCCAGAA AATGGCTTGG TAGCATACAA AGATGGGAAA 240 241 CTCGTGTCTA AACAGAATAT TCAAGGTCAC CTGGGTGAGG CCCTGATTCA AGATTTAATC 300 301 AACTACTGTC TGAGCTACAT TGCGAAAATT AAGCTCCCAA AGAAGAGGGG TACCTTCATT 360 361 GAATTCCGAA ACGGGATGTT GAACGTGTCT CCCATCGGAA GGAGCTGCAG CCAAGAAGAA 420 421 CGCATTGAGT TCTACGAACT TGACAAAAAA GAAAATATCA GACAAAAATT CGTGGAGGAT 480 481 CTGCGGCAAG AGTTTGCAGG GAAAGGCCTC ACATTTTCCA TAGGAGGCCA GATCAGCTTT 540 541 GATGTCTTCC CCGACGGCTG GGACAAGAGG TACTGCCTGG GGCACGTGGA GAAGGACGGC 600 601 TATAAGACCA TTTATTTCTT TGGAGACAAA ACTATGCCTG GCGGGAACGA CCACGAGATC 660 661 TTTGAGGACC CCCGGACCGT GAGCTACACC GTGACGGCGC CCGAGGACAC CCGCAGGATC 720 721 TGCCAGGAGC TCTTCTGCTG A 741 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Molecular Function | Phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | Mannose metabolic process | |
Biological Process | Protein N-linked glycosylation | |
Biological Process | Protein targeting to ER |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Bot-2171 | Bos taurus | 94.31 | 2e-173 | 484 |
| LLPS-Ova-3595 | Ovis aries | 94.29 | 3e-172 | 482 |
| LLPS-Chs-0461 | Chlorocebus sabaeus | 93.88 | 1e-169 | 475 |
| LLPS-Cea-2427 | Cercocebus atys | 93.88 | 1e-169 | 475 |
| LLPS-Paa-4064 | Papio anubis | 93.88 | 1e-169 | 475 |
| LLPS-Rhb-2784 | Rhinopithecus bieti | 93.88 | 1e-169 | 475 |
| LLPS-Tut-1974 | Tursiops truncatus | 93.5 | 4e-172 | 481 |
| LLPS-Gog-0970 | Gorilla gorilla | 93.47 | 1e-168 | 473 |
| LLPS-Man-2536 | Macaca nemestrina | 93.47 | 2e-169 | 475 |
| LLPS-Mam-2662 | Macaca mulatta | 93.47 | 2e-169 | 475 |
| LLPS-Eqc-1465 | Equus caballus | 93.33 | 7e-163 | 461 |
| LLPS-Orc-3038 | Oryctolagus cuniculus | 93.09 | 1e-167 | 471 |
| LLPS-Maf-3020 | Macaca fascicularis | 93.06 | 3e-168 | 472 |
| LLPS-Pat-4559 | Pan troglodytes | 93.06 | 3e-168 | 472 |
| LLPS-Nol-3370 | Nomascus leucogenys | 93.06 | 4e-168 | 471 |
| LLPS-Loa-2550 | Loxodonta africana | 93.0 | 2e-164 | 462 |
| LLPS-Hos-4391 | Homo sapiens | 92.65 | 1e-167 | 470 |
| LLPS-Pap-3166 | Pan paniscus | 92.65 | 2e-167 | 470 |
| LLPS-Otg-4430 | Otolemur garnettii | 92.24 | 4e-167 | 469 |
| LLPS-Fec-3257 | Felis catus | 92.24 | 1e-167 | 470 |
| LLPS-Ict-3072 | Ictidomys tridecemlineatus | 92.24 | 7e-167 | 468 |
| LLPS-Caf-4393 | Canis familiaris | 92.24 | 2e-166 | 467 |
| LLPS-Mea-1391 | Mesocricetus auratus | 92.05 | 5e-162 | 456 |
| LLPS-Ran-1769 | Rattus norvegicus | 91.21 | 2e-160 | 452 |
| LLPS-Caj-3877 | Callithrix jacchus | 91.02 | 3e-165 | 464 |
| LLPS-Aon-3742 | Aotus nancymaae | 91.02 | 2e-165 | 464 |
| LLPS-Dio-2476 | Dipodomys ordii | 91.02 | 3e-164 | 461 |
| LLPS-Urm-3732 | Ursus maritimus | 91.02 | 3e-163 | 459 |
| LLPS-Myl-4475 | Myotis lucifugus | 90.69 | 1e-163 | 460 |
| LLPS-Fud-2608 | Fukomys damarensis | 90.61 | 7e-163 | 458 |
| LLPS-Mup-2594 | Mustela putorius furo | 90.61 | 2e-163 | 459 |
| LLPS-Aim-3481 | Ailuropoda melanoleuca | 90.36 | 6e-163 | 459 |
| LLPS-Mum-3303 | Mus musculus | 89.54 | 1e-156 | 442 |
| LLPS-Cap-2344 | Cavia porcellus | 89.02 | 1e-161 | 455 |
| LLPS-Sah-3779 | Sarcophilus harrisii | 85.71 | 3e-155 | 439 |
| LLPS-Mod-0366 | Monodelphis domestica | 85.31 | 3e-155 | 439 |
| LLPS-Gaga-1499 | Gallus gallus | 84.15 | 4e-151 | 428 |
| LLPS-Anp-0165 | Anas platyrhynchos | 84.0 | 5e-137 | 392 |
| LLPS-Pes-1966 | Pelodiscus sinensis | 82.51 | 3e-127 | 367 |
| LLPS-Fia-0727 | Ficedula albicollis | 81.65 | 1e-131 | 378 |
| LLPS-Tag-1558 | Taeniopygia guttata | 81.22 | 3e-147 | 419 |
| LLPS-Ora-1651 | Ornithorhynchus anatinus | 79.08 | 2e-135 | 388 |
| LLPS-Lac-2489 | Latimeria chalumnae | 76.23 | 3e-131 | 378 |
| LLPS-Orl-1009 | Oryzias latipes | 74.48 | 9e-134 | 384 |
| LLPS-Asm-0601 | Astyanax mexicanus | 73.64 | 1e-131 | 379 |
| LLPS-Orn-3130 | Oreochromis niloticus | 73.64 | 6e-132 | 380 |
| LLPS-Dar-3836 | Danio rerio | 73.64 | 2e-131 | 378 |
| LLPS-Scf-2592 | Scleropages formosus | 73.22 | 6e-132 | 380 |
| LLPS-Icp-3469 | Ictalurus punctatus | 72.8 | 3e-128 | 370 |
| LLPS-Xet-3776 | Xenopus tropicalis | 72.76 | 7e-133 | 382 |
| LLPS-Leo-1469 | Lepisosteus oculatus | 72.33 | 1e-133 | 384 |
| LLPS-Gaa-3428 | Gasterosteus aculeatus | 70.59 | 1e-124 | 361 |
| LLPS-Pof-2953 | Poecilia formosa | 69.67 | 1e-128 | 371 |
| LLPS-Scm-1068 | Scophthalmus maximus | 68.33 | 3e-117 | 343 |
| LLPS-Mal-3908 | Mandrillus leucophaeus | 68.05 | 5e-120 | 350 |
| LLPS-Cas-0723 | Carlito syrichta | 68.05 | 6e-120 | 350 |
| LLPS-Poa-2887 | Pongo abelii | 68.05 | 3e-119 | 348 |
| LLPS-Tar-0239 | Takifugu rubripes | 67.36 | 3e-123 | 358 |
| LLPS-Cii-1967 | Ciona intestinalis | 66.94 | 3e-120 | 350 |
| LLPS-Meg-1448 | Meleagris gallopavo | 66.37 | 2e-105 | 311 |
| LLPS-Cis-1921 | Ciona savignyi | 66.12 | 1e-116 | 341 |
| LLPS-Anc-2624 | Anolis carolinensis | 65.87 | 1e-118 | 347 |
| LLPS-Ere-0494 | Erinaceus europaeus | 64.73 | 4e-110 | 325 |
| LLPS-Ten-2084 | Tetraodon nigroviridis | 61.97 | 7e-27 | 104 |
| LLPS-Php-2472 | Physcomitrella patens | 61.92 | 6e-104 | 309 |
| LLPS-Via-0283 | Vigna angularis | 61.68 | 1e-84 | 258 |
| LLPS-Hea-2445 | Helianthus annuus | 61.54 | 8e-97 | 291 |
| LLPS-Sot-1670 | Solanum tuberosum | 61.38 | 3e-102 | 305 |
| LLPS-Pot-2710 | Populus trichocarpa | 61.04 | 5e-96 | 288 |
| LLPS-Thc-2312 | Theobroma cacao | 60.98 | 1e-95 | 287 |
| LLPS-Glm-2176 | Glycine max | 60.98 | 4e-98 | 294 |
| LLPS-Mae-2506 | Manihot esculenta | 60.98 | 4e-95 | 286 |
| LLPS-Cus-0928 | Cucumis sativus | 60.57 | 5e-96 | 288 |
| LLPS-Phv-2322 | Phaseolus vulgaris | 60.57 | 7e-97 | 290 |
| LLPS-Nia-1746 | Nicotiana attenuata | 60.57 | 5e-99 | 296 |
| LLPS-Viv-0775 | Vitis vinifera | 60.57 | 8e-100 | 298 |
| LLPS-Gor-0236 | Gossypium raimondii | 60.57 | 3e-95 | 286 |
| LLPS-Osl-0614 | Ostreococcus lucimarinus | 60.34 | 2e-101 | 302 |
| LLPS-Brd-1778 | Brachypodium distachyon | 60.25 | 5e-101 | 301 |
| LLPS-Amt-0104 | Amborella trichopoda | 60.25 | 2e-94 | 287 |
| LLPS-Met-1268 | Medicago truncatula | 60.16 | 6e-102 | 303 |
| LLPS-Prp-0792 | Prunus persica | 60.16 | 2e-102 | 304 |
| LLPS-Chr-0675 | Chlamydomonas reinhardtii | 59.83 | 3e-101 | 301 |
| LLPS-Arl-1609 | Arabidopsis lyrata | 59.76 | 2e-100 | 299 |
| LLPS-Art-2469 | Arabidopsis thaliana | 59.76 | 3e-100 | 299 |
| LLPS-Coc-2217 | Corchorus capsularis | 59.76 | 2e-94 | 285 |
| LLPS-Sei-1773 | Setaria italica | 59.68 | 1e-100 | 300 |
| LLPS-Sob-2116 | Sorghum bicolor | 59.68 | 8e-102 | 303 |
| LLPS-Scc-1595 | Schizosaccharomyces cryophilus | 59.67 | 6e-98 | 293 |
| LLPS-Xim-2624 | Xiphophorus maculatus | 59.63 | 1e-109 | 325 |
| LLPS-Lep-0066 | Leersia perrieri | 59.44 | 4e-98 | 300 |
| LLPS-Hov-0713 | Hordeum vulgare | 59.27 | 5e-101 | 305 |
| LLPS-Orbr-1923 | Oryza brachyantha | 59.27 | 9e-101 | 300 |
| LLPS-Zem-1304 | Zea mays | 59.27 | 2e-101 | 302 |
| LLPS-Scj-0335 | Schizosaccharomyces japonicus | 59.09 | 3e-94 | 284 |
| LLPS-Sol-1925 | Solanum lycopersicum | 59.02 | 3e-98 | 294 |
| LLPS-Sac-0556 | Saccharomyces cerevisiae | 59.0 | 4e-94 | 284 |
| LLPS-Bro-2824 | Brassica oleracea | 58.94 | 2e-98 | 294 |
| LLPS-Orp-2386 | Oryza punctata | 58.82 | 3e-94 | 298 |
| LLPS-Orni-2222 | Oryza nivara | 58.7 | 1e-98 | 295 |
| LLPS-Orb-0231 | Oryza barthii | 58.7 | 9e-99 | 295 |
| LLPS-Ors-1382 | Oryza sativa | 58.7 | 1e-98 | 295 |
| LLPS-Org-2136 | Oryza glaberrima | 58.7 | 1e-98 | 295 |
| LLPS-Orm-1169 | Oryza meridionalis | 58.7 | 6e-99 | 296 |
| LLPS-Orr-0929 | Oryza rufipogon | 58.7 | 1e-98 | 295 |
| LLPS-Mel-0073 | Melampsora laricipopulina | 58.61 | 3e-96 | 289 |
| LLPS-Sem-1232 | Selaginella moellendorffii | 58.58 | 3e-95 | 286 |
| LLPS-Chc-0769 | Chondrus crispus | 58.58 | 4e-95 | 286 |
| LLPS-Brn-1325 | Brassica napus | 58.54 | 2e-97 | 292 |
| LLPS-Abg-1126 | Absidia glauca | 58.41 | 2e-40 | 141 |
| LLPS-Orgl-2193 | Oryza glumaepatula | 58.3 | 1e-97 | 292 |
| LLPS-Dac-0894 | Daucus carota | 58.06 | 1e-81 | 251 |
| LLPS-Brr-1355 | Brassica rapa | 58.06 | 1e-96 | 290 |
| LLPS-Put-0420 | Puccinia triticina | 57.87 | 1e-91 | 278 |
| LLPS-Pug-1062 | Puccinia graminis | 57.72 | 2e-96 | 290 |
| LLPS-Asn-1633 | Aspergillus nidulans | 57.66 | 2e-91 | 277 |
| LLPS-Mua-0992 | Musa acuminata | 57.33 | 2e-48 | 164 |
| LLPS-Ori-2268 | Oryza indica | 56.47 | 5e-94 | 283 |
| LLPS-Tra-1951 | Triticum aestivum | 56.45 | 1e-97 | 293 |
| LLPS-Tum-1074 | Tuber melanosporum | 56.38 | 3e-91 | 277 |
| LLPS-Gas-0833 | Galdieria sulphuraria | 56.33 | 1e-92 | 280 |
| LLPS-Scp-0397 | Schizosaccharomyces pombe | 56.2 | 4e-92 | 279 |
| LLPS-Yal-1019 | Yarrowia lipolytica | 55.65 | 5e-93 | 281 |
| LLPS-Drm-2311 | Drosophila melanogaster | 55.6 | 3e-91 | 276 |
| LLPS-Ast-0171 | Aspergillus terreus | 55.36 | 7e-84 | 257 |
| LLPS-Gag-1551 | Gaeumannomyces graminis | 55.02 | 8e-92 | 278 |
| LLPS-Asni-1324 | Aspergillus niger | 54.84 | 2e-89 | 273 |
| LLPS-Nef-1289 | Neosartorya fischeri | 54.84 | 1e-89 | 273 |
| LLPS-Asg-1167 | Ashbya gossypii | 54.81 | 1e-90 | 275 |
| LLPS-Trr-1259 | Trichoderma reesei | 54.8 | 8e-91 | 276 |
| LLPS-Cae-0546 | Caenorhabditis elegans | 54.58 | 2e-93 | 282 |
| LLPS-Spr-1274 | Sporisorium reilianum | 54.51 | 2e-90 | 275 |
| LLPS-Usm-0838 | Ustilago maydis | 54.3 | 1e-89 | 273 |
| LLPS-Trv-0095 | Trichoderma virens | 54.0 | 2e-86 | 265 |
| LLPS-Map-1140 | Magnaporthe poae | 53.82 | 1e-89 | 272 |
| LLPS-Asf-1285 | Aspergillus flavus | 53.63 | 5e-90 | 274 |
| LLPS-Aso-1531 | Aspergillus oryzae | 53.63 | 5e-90 | 274 |
| LLPS-Tru-0138 | Triticum urartu | 53.45 | 1e-95 | 288 |
| LLPS-Kop-0143 | Komagataella pastoris | 53.33 | 2e-90 | 275 |
| LLPS-Blg-1274 | Blumeria graminis | 53.01 | 2e-85 | 262 |
| LLPS-Asc-1365 | Aspergillus clavatus | 52.82 | 1e-86 | 265 |
| LLPS-Fuv-0073 | Fusarium verticillioides | 52.8 | 3e-85 | 262 |
| LLPS-Fuo-1336 | Fusarium oxysporum | 52.8 | 3e-85 | 262 |
| LLPS-Coo-1602 | Colletotrichum orbiculare | 52.61 | 2e-83 | 257 |
| LLPS-Crn-1449 | Cryptococcus neoformans | 52.28 | 3e-87 | 266 |
| LLPS-Fus-0853 | Fusarium solani | 52.24 | 5e-88 | 269 |
| LLPS-Mao-0824 | Magnaporthe oryzae | 52.21 | 3e-86 | 264 |
| LLPS-Cogr-1486 | Colletotrichum graminicola | 52.21 | 5e-85 | 261 |
| LLPS-Beb-0801 | Beauveria bassiana | 52.0 | 6e-86 | 263 |
| LLPS-Ved-0529 | Verticillium dahliae | 52.0 | 2e-86 | 265 |
| LLPS-Pyt-1481 | Pyrenophora teres | 51.63 | 2e-79 | 247 |
| LLPS-Lem-1146 | Leptosphaeria maculans | 51.61 | 7e-79 | 245 |
| LLPS-Nec-0520 | Neurospora crassa | 51.29 | 3e-88 | 270 |
| LLPS-Asfu-0786 | Aspergillus fumigatus | 51.21 | 5e-77 | 239 |
| LLPS-Pytr-0726 | Pyrenophora triticirepentis | 50.81 | 3e-78 | 243 |
| LLPS-Dos-1611 | Dothistroma septosporum | 50.6 | 1e-83 | 258 |
| LLPS-Miv-0792 | Microbotryum violaceum | 49.45 | 2e-52 | 177 |
| LLPS-Zyt-1513 | Zymoseptoria tritici | 49.44 | 1e-80 | 250 |
| LLPS-Cym-0317 | Cyanidioschyzon merolae | 48.54 | 1e-79 | 247 |
| LLPS-Scs-0639 | Sclerotinia sclerotiorum | 48.5 | 2e-46 | 159 |
| LLPS-Vir-1480 | Vigna radiata | 44.03 | 5e-62 | 202 |
| LLPS-Cog-0919 | Colletotrichum gloeosporioides | 41.74 | 8e-52 | 174 |
| LLPS-Phn-0938 | Phaeosphaeria nodorum | 37.84 | 1e-16 | 80.1 |