• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Myl-4475
PMM2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Phosphomannomutase
Gene Name: PMM2
Ensembl Gene: ENSMLUG00000009714.2
Ensembl Protein: ENSMLUP00000008846.2
Organism: Myotis lucifugus
Taxa ID: 59463
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSMLUT00000009706.2ENSMLUP00000008846.2
UniProtL7N1I8, L7N1I8_MYOLU
GeneBankAAPE02020906

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAPGPALCL  FDVDGTLTAP  RQKITKEMDD  FLQKLRQKVK  IGVVGGSDFE  KVQEQLGNDV  60
61    AVVEKYDYVF  PENGLVAYKD  GKFLCKQSIQ  GHLGEALIQD  LINYCLSYIA  KIQLPKKRGT  120
121   FIEFRNGMLN  VSPIGRSCSQ  EERIEFYELD  KKENIRQKFV  ADLQKEFAGK  GLTFSIGGQI  180
181   SIDVFPHGWD  KRYCLGHVEK  DGYKTIYFFG  DKTMPGGNDH  EIFTDQRTMG  YTVMAPEDTR  240
241   RICEELFS  248
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGCGC  CGGGCCCCGC  GCTCTGCCTC  TTCGACGTGG  ACGGGACCCT  GACGGCCCCG  60
61    CGGCAGAAAA  TTACCAAAGA  AATGGATGAC  TTTCTACAAA  AATTGAGGCA  GAAGGTCAAA  120
121   ATCGGAGTGG  TAGGCGGCTC  GGACTTTGAG  AAAGTGCAGG  AGCAGCTGGG  AAATGATGTT  180
181   GCAGTGGTTG  AAAAGTATGA  TTATGTGTTT  CCAGAAAATG  GCTTGGTGGC  GTACAAAGAT  240
241   GGGAAATTCT  TGTGTAAACA  GAGTATCCAA  GGTCACTTGG  GTGAGGCCCT  AATCCAAGAC  300
301   TTAATCAACT  ACTGTCTCAG  CTACATTGCA  AAAATTCAGC  TCCCAAAGAA  GAGGGGCACT  360
361   TTCATCGAAT  TCCGGAACGG  GATGTTAAAT  GTGTCTCCTA  TTGGACGAAG  CTGCAGCCAA  420
421   GAGGAACGCA  TTGAATTCTA  CGAGCTCGAT  AAAAAAGAAA  ACATACGACA  GAAATTTGTA  480
481   GCAGATCTGC  AGAAAGAGTT  CGCAGGAAAA  GGCCTCACGT  TTTCCATAGG  AGGCCAGATC  540
541   AGCATCGATG  TCTTTCCTCA  TGGATGGGAC  AAGAGGTACT  GCCTGGGACA  CGTGGAAAAG  600
601   GACGGCTATA  AGACCATTTA  TTTCTTTGGA  GACAAAACCA  TGCCAGGTGG  GAACGACCAT  660
661   GAGATCTTCA  CGGACCAGAG  GACCATGGGC  TACACCGTGA  TGGCCCCTGA  GGACACGCGC  720
721   AGGATCTGTG  AAGAGCTCTT  CTCCTAA  747

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Isomerase
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
Phosphomannomutase activity
Biological Process
GDP-mannose biosynthetic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Eqc-1465Equus caballus93.85e-165 466
LLPS-Paa-4064Papio anubis93.553e-170 477
LLPS-Chs-0461Chlorocebus sabaeus93.553e-170 477
LLPS-Cea-2427Cercocebus atys93.553e-170 477
LLPS-Nol-3370Nomascus leucogenys93.554e-170 476
LLPS-Pat-4559Pan troglodytes93.554e-170 477
LLPS-Pap-3166Pan paniscus93.552e-170 478
LLPS-Mea-1391Mesocricetus auratus93.392e-164 462
LLPS-Gog-0970Gorilla gorilla93.152e-169 475
LLPS-Mam-2662Macaca mulatta93.154e-170 476
LLPS-Hos-4391Homo sapiens93.151e-169 476
LLPS-Man-2536Macaca nemestrina93.154e-170 476
LLPS-Orc-3038Oryctolagus cuniculus93.124e-169 474
LLPS-Maf-3020Macaca fascicularis92.744e-169 474
LLPS-Ict-3072Ictidomys tridecemlineatus92.746e-169 474
LLPS-Rhb-2784Rhinopithecus bieti92.741e-168 473
LLPS-Aim-3481Ailuropoda melanoleuca92.372e-167 470
LLPS-Dio-2476Dipodomys ordii92.319e-167 468
LLPS-Urm-3732Ursus maritimus91.941e-165 465
LLPS-Fec-3257Felis catus91.945e-168 471
LLPS-Mup-2594Mustela putorius furo91.91e-165 465
LLPS-Ova-3595Ovis aries91.98e-167 468
LLPS-Bot-2171Bos taurus91.92e-166 468
LLPS-Loa-2550Loxodonta africana91.741e-164 462
LLPS-Fud-2608Fukomys damarensis91.532e-165 465
LLPS-Caj-3877Callithrix jacchus91.52e-166 467
LLPS-Aon-3742Aotus nancymaae91.51e-166 468
LLPS-Otg-4430Otolemur garnettii91.56e-166 466
LLPS-Caf-4393Canis familiaris91.133e-165 464
LLPS-Ran-1769Rattus norvegicus90.872e-159 449
LLPS-Sus-4652Sus scrofa90.691e-163 460
LLPS-Cap-2344Cavia porcellus90.322e-164 462
LLPS-Tut-1974Tursiops truncatus90.283e-164 462
LLPS-Mum-3303Mus musculus89.631e-156 442
LLPS-Sah-3779Sarcophilus harrisii87.457e-160 451
LLPS-Mod-0366Monodelphis domestica87.452e-159 450
LLPS-Pes-1966Pelodiscus sinensis84.894e-132 379
LLPS-Anp-0165Anas platyrhynchos84.444e-141 402
LLPS-Fia-0727Ficedula albicollis83.646e-134 384
LLPS-Gaga-1499Gallus gallus83.471e-150 427
LLPS-Tag-1558Taeniopygia guttata83.04e-150 426
LLPS-Ora-1651Ornithorhynchus anatinus80.914e-140 400
LLPS-Lac-2489Latimeria chalumnae75.612e-128 371
LLPS-Xet-3776Xenopus tropicalis74.199e-136 390
LLPS-Scf-2592Scleropages formosus73.865e-131 377
LLPS-Asm-0601Astyanax mexicanus73.442e-129 374
LLPS-Orl-1009Oryzias latipes73.034e-130 375
LLPS-Leo-1469Lepisosteus oculatus72.552e-132 381
LLPS-Icp-3469Ictalurus punctatus72.24e-126 365
LLPS-Orn-3130Oreochromis niloticus71.789e-128 369
LLPS-Dar-3836Danio rerio71.374e-126 365
LLPS-Pof-2953Poecilia formosa68.73e-124 360
LLPS-Gaa-3428Gasterosteus aculeatus68.336e-119 347
LLPS-Cii-1967Ciona intestinalis67.772e-120 350
LLPS-Mal-3908Mandrillus leucophaeus67.631e-118 347
LLPS-Tar-0239Takifugu rubripes67.631e-120 351
LLPS-Cas-0723Carlito syrichta67.631e-118 347
LLPS-Poa-2887Pongo abelii67.633e-118 345
LLPS-Scm-1068Scophthalmus maximus67.53e-117 343
LLPS-Cis-1921Ciona savignyi66.122e-115 338
LLPS-Meg-1448Meleagris gallopavo65.499e-105 310
LLPS-Anc-2624Anolis carolinensis64.683e-118 345
LLPS-Ere-0494Erinaceus europaeus63.95e-108 320
LLPS-Lep-0066Leersia perrieri61.112e-1373.2
LLPS-Php-2472Physcomitrella patens60.583e-99 297
LLPS-Ten-2084Tetraodon nigroviridis60.565e-25 100
LLPS-Mae-2506Manihot esculenta60.089e-93 280
LLPS-Chr-0675Chlamydomonas reinhardtii59.751e-99 298
LLPS-Amt-0104Amborella trichopoda59.755e-93 283
LLPS-Glm-2176Glycine max59.685e-94 283
LLPS-Sac-0556Saccharomyces cerevisiae59.51e-94 285
LLPS-Scc-1595Schizosaccharomyces cryophilus59.52e-95 287
LLPS-Met-1268Medicago truncatula59.272e-98 295
LLPS-Arl-1609Arabidopsis lyrata59.275e-97 291
LLPS-Sot-1670Solanum tuberosum59.275e-98 294
LLPS-Phv-2322Phaseolus vulgaris59.271e-92 280
LLPS-Art-2469Arabidopsis thaliana59.275e-97 291
LLPS-Xim-2624Xiphophorus maculatus59.268e-110 326
LLPS-Via-0283Vigna angularis59.266e-80 246
LLPS-Osl-0614Ostreococcus lucimarinus59.07e-96 288
LLPS-Brd-1778Brachypodium distachyon58.924e-98 294
LLPS-Orbr-1923Oryza brachyantha58.929e-97 290
LLPS-Cus-0928Cucumis sativus58.874e-93 281
LLPS-Hea-2445Helianthus annuus58.876e-91 276
LLPS-Thc-2312Theobroma cacao58.871e-91 277
LLPS-Brn-1325Brassica napus58.872e-95 287
LLPS-Bro-2824Brassica oleracea58.874e-95 286
LLPS-Gor-0236Gossypium raimondii58.871e-91 277
LLPS-Pot-2710Populus trichocarpa58.83e-92 279
LLPS-Scj-0335Schizosaccharomyces japonicus58.682e-91 277
LLPS-Pug-1062Puccinia graminis58.541e-95 288
LLPS-Asn-1633Aspergillus nidulans58.474e-91 277
LLPS-Prp-0792Prunus persica58.473e-98 294
LLPS-Viv-0775Vitis vinifera58.475e-97 291
LLPS-Sei-1773Setaria italica58.41e-97 292
LLPS-Hov-0713Hordeum vulgare58.47e-99 300
LLPS-Sob-2116Sorghum bicolor58.41e-98 295
LLPS-Mel-0073Melampsora laricipopulina58.22e-92 280
LLPS-Coc-2217Corchorus capsularis58.064e-91 276
LLPS-Nia-1746Nicotiana attenuata58.064e-95 286
LLPS-Zem-1304Zea mays58.04e-98 294
LLPS-Brr-1355Brassica rapa58.03e-93 281
LLPS-Orp-2386Oryza punctata57.921e-90 288
LLPS-Put-0420Puccinia triticina57.875e-89 271
LLPS-Orni-2222Oryza nivara57.833e-95 286
LLPS-Orb-0231Oryza barthii57.833e-95 286
LLPS-Org-2136Oryza glaberrima57.833e-95 286
LLPS-Orm-1169Oryza meridionalis57.831e-95 287
LLPS-Orr-0929Oryza rufipogon57.833e-95 286
LLPS-Ors-1382Oryza sativa57.833e-95 286
LLPS-Sem-1232Selaginella moellendorffii57.688e-93 280
LLPS-Tum-1074Tuber melanosporum57.615e-91 276
LLPS-Abg-1126Absidia glauca57.527e-39 137
LLPS-Orgl-2193Oryza glumaepatula57.434e-94 284
LLPS-Sol-1925Solanum lycopersicum57.322e-94 285
LLPS-Chc-0769Chondrus crispus57.263e-90 274
LLPS-Mua-0992Musa acuminata57.242e-47 161
LLPS-Dac-0894Daucus carota56.622e-78 243
LLPS-Ori-2268Oryza indica56.474e-93 281
LLPS-Yal-1019Yarrowia lipolytica56.436e-92 278
LLPS-Trv-0095Trichoderma virens56.41e-90 275
LLPS-Scp-0397Schizosaccharomyces pombe56.381e-90 275
LLPS-Asni-1324Aspergillus niger56.053e-89 272
LLPS-Nef-1289Neosartorya fischeri56.052e-89 272
LLPS-Asg-1167Ashbya gossypii56.029e-89 270
LLPS-Kop-0143Komagataella pastoris55.798e-92 278
LLPS-Gas-0833Galdieria sulphuraria55.654e-90 273
LLPS-Asf-1285Aspergillus flavus55.652e-93 283
LLPS-Aso-1531Aspergillus oryzae55.652e-93 283
LLPS-Trr-1259Trichoderma reesei55.65e-91 276
LLPS-Ast-0171Aspergillus terreus55.568e-84 257
LLPS-Cae-0546Caenorhabditis elegans55.386e-95 286
LLPS-Tra-1951Triticum aestivum55.24e-95 286
LLPS-Fuv-0073Fusarium verticillioides55.22e-89 272
LLPS-Fuo-1336Fusarium oxysporum55.22e-89 272
LLPS-Gag-1551Gaeumannomyces graminis55.022e-90 275
LLPS-Blg-1274Blumeria graminis54.621e-86 265
LLPS-Spr-1274Sporisorium reilianum54.473e-88 270
LLPS-Asc-1365Aspergillus clavatus54.448e-88 268
LLPS-Usm-0838Ustilago maydis54.35e-88 269
LLPS-Coo-1602Colletotrichum orbiculare54.222e-86 265
LLPS-Map-1140Magnaporthe poae53.822e-87 267
LLPS-Drm-2311Drosophila melanogaster53.725e-89 271
LLPS-Crn-1449Cryptococcus neoformans53.535e-88 269
LLPS-Cogr-1486Colletotrichum graminicola53.413e-88 269
LLPS-Lem-1146Leptosphaeria maculans53.232e-81 252
LLPS-Beb-0801Beauveria bassiana53.28e-86 263
LLPS-Mao-0824Magnaporthe oryzae53.014e-89 271
LLPS-Tru-0138Triticum urartu52.997e-93 281
LLPS-Ved-0529Verticillium dahliae52.81e-86 266
LLPS-Fus-0853Fusarium solani52.245e-88 269
LLPS-Dos-1611Dothistroma septosporum52.214e-85 261
LLPS-Asfu-0786Aspergillus fumigatus52.021e-76 239
LLPS-Pyt-1481Pyrenophora teres51.631e-80 250
LLPS-Pytr-0726Pyrenophora triticirepentis51.631e-80 250
LLPS-Zyt-1513Zymoseptoria tritici51.313e-84 259
LLPS-Nec-0520Neurospora crassa50.03e-84 259
LLPS-Miv-0792Microbotryum violaceum50.01e-51 175
LLPS-Scs-0639Sclerotinia sclerotiorum49.71e-47 162
LLPS-Cym-0317Cyanidioschyzon merolae47.38e-75 235
LLPS-Vir-1480Vigna radiata43.499e-61 199
LLPS-Cog-0919Colletotrichum gloeosporioides43.441e-55 184
LLPS-Phn-0938Phaeosphaeria nodorum41.445e-1884.3