DrLLPS - Data resource of LLPS

LLPS-Crn-1449
CNH00170

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Phosphomannomutase
Gene Name:	CNH00170
Ensembl Gene:	CNH00170
Ensembl Protein:	AAW44905
Organism:	Cryptococcus neoformans
Taxa ID:	214684
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0556	P07283	Client	Stress granule, Others	62.95	8e-112	330

▼ FUNCTION

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	AAW44905	AAW44905
UniProt		Q5KC89, Q5KC89_CRYNJ, Q55JH0
GeneBank	AE017348	AAW44905.1
RefSeq	XM_572212.1	XP_572212.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MSAPQPASAT IFPPGVTPFA QRRLPKTICM FDVDGTLSLA RQSATPEMFA TLRKLRESCA 60 61 IAFVGGSDLT KILEQVGGDQ GLSNFDYGFA ENGLIAYKLG QQLESASFIK HVGEEEYKKL 120 121 VNWILRYLSE VDIPIKRGTF VEFRNGMINV SPIGRNASIQ ERIDFEKYDK EHGIRGDMVA 180 181 KLEREFLHLG LTFAIGGQIS FDIFPKGWDK TYSLRHIEGE GFEEIHFFGD KTYKGGNDYE 240 241 IFSDPRTIGH TVTSPEHTMQ LLDELFLTTA P 271
Nucleotide CDS Sequence (FASTA)
1 ATGTCCGCCC CTCAGCCCGC CTCTGCCACC ATCTTTCCCC CCGGCGTCAC CCCCTTCGCC 60 61 CAGCGAAGGC TCCCCAAGAC CATCTGCATG TTTGACGTCG ATGGCACCCT TTCTCTCGCC 120 121 CGTCAGAGCG CGACCCCCGA GATGTTTGCT ACCCTCCGCA AACTCCGTGA GAGCTGCGCC 180 181 ATCGCCTTTG TGGGTGGCTC CGACCTCACC AAGATCCTGG AGCAGGTCGG CGGGGACCAA 240 241 GGGCTGAGCA ATTTTGACTA TGGGTTTGCA GAGAATGGGT TGATCGCGTA CAAGTTGGGC 300 301 CAGCAGCTCG AGTCGGCGAG TTTTATCAAG CATGTAGGAG AGGAGGAGTA TAAGAAGCTT 360 361 GTCAATTGGA TTTTGAGGTA TCTCTCCGAA GTGGACATTC CCATCAAGCG AGGCACGTTT 420 421 GTCGAATTTC GAAACGGTAT GATCAACGTC TCCCCTATCG GCAGAAACGC ATCCATCCAG 480 481 GAGCGAATCG ATTTTGAAAA GTATGACAAG GAGCATGGTA TTCGGGGAGA CATGGTCGCC 540 541 AAGCTCGAGC GAGAGTTTTT GCATCTTGGA TTGACTTTTG CGATTGGCGG TCAGATTAGT 600 601 TTTGACATTT TCCCCAAGGG CTGGGACAAG ACATATTCGC TTAGGCATAT CGAGGGTGAA 660 661 GGCTTTGAAG AGATTCACTT TTTCGGCGAC AAGACCTACA AGGGCGGTAA TGATTATGAG 720 721 ATCTTTTCCG ACCCCCGAAC TATCGGTCAC ACCGTCACCA GCCCCGAGCA TACTATGCAG 780 781 CTCCTCGACG AGTTGTTTTT GACGACTGCT CCTTGA 816

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0963	Cytoplasm
KW-0413	Isomerase
KW-1185	Reference proteome

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005829	Cellular Component	Cytosol
GO:0004615	Molecular Function	Phosphomannomutase activity
GO:0009298	Biological Process	GDP-mannose biosynthetic process
GO:0006013	Biological Process	Mannose metabolic process
GO:0006487	Biological Process	Protein N-linked glycosylation
GO:0045047	Biological Process	Protein targeting to ER

▼ KEGG

cne:CNH00170

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Put-0420	Puccinia triticina	65.99	7e-105	313
LLPS-Pug-1062	Puccinia graminis	65.22	7e-105	312
LLPS-Mel-0073	Melampsora laricipopulina	65.08	1e-104	311
LLPS-Kop-0143	Komagataella pastoris	64.52	4e-105	313
LLPS-Scj-0335	Schizosaccharomyces japonicus	64.43	6e-108	320
LLPS-Tum-1074	Tuber melanosporum	63.5	4e-105	313
LLPS-Scc-1595	Schizosaccharomyces cryophilus	62.99	2e-105	314
LLPS-Sac-0556	Saccharomyces cerevisiae	62.95	5e-100	300
LLPS-Scp-0397	Schizosaccharomyces pombe	61.81	2e-102	306
LLPS-Ten-2084	Tetraodon nigroviridis	61.64	3e-16	76.3
LLPS-Miv-0792	Microbotryum violaceum	60.73	4e-78	244
LLPS-Yal-1019	Yarrowia lipolytica	60.71	2e-94	285
LLPS-Trr-1259	Trichoderma reesei	60.08	1e-103	310
LLPS-Asg-1167	Ashbya gossypii	59.76	4e-99	297
LLPS-Map-1140	Magnaporthe poae	59.3	1e-96	291
LLPS-Brn-1325	Brassica napus	58.85	2e-87	268
LLPS-Nec-0520	Neurospora crassa	58.7	2e-105	314
LLPS-Bro-2824	Brassica oleracea	58.61	2e-87	267
LLPS-Amt-0104	Amborella trichopoda	58.51	2e-85	265
LLPS-Gag-1551	Gaeumannomyces graminis	58.43	1e-93	284
LLPS-Abg-1126	Absidia glauca	58.41	3e-32	120
LLPS-Ved-0529	Verticillium dahliae	58.3	2e-95	289
LLPS-Brr-1355	Brassica rapa	58.23	7e-90	274
LLPS-Ast-0171	Aspergillus terreus	57.94	1e-88	270
LLPS-Spr-1274	Sporisorium reilianum	57.89	8e-101	302
LLPS-Trv-0095	Trichoderma virens	57.79	3e-100	301
LLPS-Mao-0824	Magnaporthe oryzae	57.75	9e-93	281
LLPS-Dos-1611	Dothistroma septosporum	57.68	4e-97	293
LLPS-Mae-2506	Manihot esculenta	57.66	2e-84	260
LLPS-Scs-0639	Sclerotinia sclerotiorum	57.63	4e-64	206
LLPS-Cogr-1486	Colletotrichum graminicola	57.63	6e-99	298
LLPS-Fuv-0073	Fusarium verticillioides	57.58	2e-102	306
LLPS-Fuo-1336	Fusarium oxysporum	57.58	2e-102	306
LLPS-Hea-2445	Helianthus annuus	57.55	3e-83	257
LLPS-Asni-1324	Aspergillus niger	57.47	6e-95	287
LLPS-Arl-1609	Arabidopsis lyrata	57.38	6e-89	271
LLPS-Blg-1274	Blumeria graminis	57.36	2e-96	291
LLPS-Sei-1773	Setaria italica	57.2	5e-90	274
LLPS-Glm-2176	Glycine max	57.14	1e-82	255
LLPS-Beb-0801	Beauveria bassiana	57.14	2e-98	296
LLPS-Sob-2116	Sorghum bicolor	57.03	1e-89	273
LLPS-Chr-0675	Chlamydomonas reinhardtii	57.02	5e-87	266
LLPS-Nef-1289	Neosartorya fischeri	56.93	5e-99	298
LLPS-Usm-0838	Ustilago maydis	56.82	3e-100	301
LLPS-Met-1268	Medicago truncatula	56.79	6e-86	264
LLPS-Lep-0066	Leersia perrieri	56.68	2e-86	271
LLPS-Orbr-1923	Oryza brachyantha	56.63	2e-89	272
LLPS-Zem-1304	Zea mays	56.63	3e-89	272
LLPS-Hov-0713	Hordeum vulgare	56.61	4e-87	270
LLPS-Dac-0894	Daucus carota	56.59	4e-69	219
LLPS-Asc-1365	Aspergillus clavatus	56.55	3e-97	293
LLPS-Zyt-1513	Zymoseptoria tritici	56.54	2e-90	276
LLPS-Art-2469	Arabidopsis thaliana	56.5	5e-89	271
LLPS-Fus-0853	Fusarium solani	56.44	5e-101	303
LLPS-Lac-2489	Latimeria chalumnae	56.43	4e-81	251
LLPS-Nia-1746	Nicotiana attenuata	56.33	1e-84	260
LLPS-Thc-2312	Theobroma cacao	56.28	9e-84	258
LLPS-Orp-2386	Oryza punctata	56.28	2e-84	273
LLPS-Coo-1602	Colletotrichum orbiculare	56.2	2e-94	286
LLPS-Scf-2592	Scleropages formosus	56.2	1e-85	263
LLPS-Coc-2217	Corchorus capsularis	56.15	4e-83	256
LLPS-Sem-1232	Selaginella moellendorffii	56.1	4e-85	261
LLPS-Via-0283	Vigna angularis	56.02	5e-70	222
LLPS-Phv-2322	Phaseolus vulgaris	55.97	5e-81	251
LLPS-Viv-0775	Vitis vinifera	55.97	4e-86	264
LLPS-Gor-0236	Gossypium raimondii	55.87	4e-83	256
LLPS-Caj-3877	Callithrix jacchus	55.83	1e-83	258
LLPS-Aon-3742	Aotus nancymaae	55.83	9e-84	258
LLPS-Orc-3038	Oryctolagus cuniculus	55.83	9e-84	258
LLPS-Orni-2222	Oryza nivara	55.82	4e-88	269
LLPS-Brd-1778	Brachypodium distachyon	55.82	1e-88	270
LLPS-Orgl-2193	Oryza glumaepatula	55.82	9e-88	268
LLPS-Ors-1382	Oryza sativa	55.82	4e-88	269
LLPS-Org-2136	Oryza glaberrima	55.82	4e-88	269
LLPS-Orr-0929	Oryza rufipogon	55.82	4e-88	269
LLPS-Orm-1169	Oryza meridionalis	55.82	2e-88	270
LLPS-Prp-0792	Prunus persica	55.69	3e-86	264
LLPS-Gas-0833	Galdieria sulphuraria	55.65	1e-83	258
LLPS-Cus-0928	Cucumis sativus	55.51	2e-82	254
LLPS-Sot-1670	Solanum tuberosum	55.51	1e-84	261
LLPS-Asn-1633	Aspergillus nidulans	55.43	9e-94	285
LLPS-Orb-0231	Oryza barthii	55.42	1e-87	268
LLPS-Tra-1951	Triticum aestivum	55.42	2e-89	273
LLPS-Chc-0769	Chondrus crispus	55.42	9e-87	266
LLPS-Dio-2476	Dipodomys ordii	55.42	6e-83	256
LLPS-Asm-0601	Astyanax mexicanus	55.37	2e-84	260
LLPS-Xet-3776	Xenopus tropicalis	55.37	7e-80	248
LLPS-Pot-2710	Populus trichocarpa	55.36	8e-80	248
LLPS-Asf-1285	Aspergillus flavus	55.17	6e-91	277
LLPS-Aso-1531	Aspergillus oryzae	55.17	6e-91	277
LLPS-Icp-3469	Ictalurus punctatus	55.14	1e-83	258
LLPS-Sol-1925	Solanum lycopersicum	55.1	1e-81	253
LLPS-Maf-3020	Macaca fascicularis	55.0	3e-82	254
LLPS-Ran-1769	Rattus norvegicus	55.0	3e-82	254
LLPS-Man-2536	Macaca nemestrina	55.0	3e-82	254
LLPS-Ict-3072	Ictidomys tridecemlineatus	55.0	7e-83	256
LLPS-Mam-2662	Macaca mulatta	55.0	3e-82	254
LLPS-Orn-3130	Oreochromis niloticus	54.96	4e-83	256
LLPS-Pof-2953	Poecilia formosa	54.96	4e-83	256
LLPS-Cii-1967	Ciona intestinalis	54.92	2e-84	260
LLPS-Pyt-1481	Pyrenophora teres	54.85	2e-94	286
LLPS-Pytr-0726	Pyrenophora triticirepentis	54.85	3e-94	286
LLPS-Otg-4430	Otolemur garnettii	54.77	4e-80	249
LLPS-Mea-1391	Mesocricetus auratus	54.58	1e-81	253
LLPS-Chs-0461	Chlorocebus sabaeus	54.58	5e-82	253
LLPS-Cea-2427	Cercocebus atys	54.58	5e-82	253
LLPS-Paa-4064	Papio anubis	54.58	5e-82	253
LLPS-Mup-2594	Mustela putorius furo	54.58	1e-81	253
LLPS-Cap-2344	Cavia porcellus	54.58	2e-82	255
LLPS-Orl-1009	Oryzias latipes	54.55	8e-84	258
LLPS-Dar-3836	Danio rerio	54.55	3e-81	252
LLPS-Eqc-1465	Equus caballus	54.43	3e-79	249
LLPS-Pes-1966	Pelodiscus sinensis	54.26	3e-68	218
LLPS-Gog-0970	Gorilla gorilla	54.17	7e-81	251
LLPS-Fud-2608	Fukomys damarensis	54.17	2e-81	252
LLPS-Mum-3303	Mus musculus	54.17	2e-80	249
LLPS-Rhb-2784	Rhinopithecus bieti	54.17	5e-81	251
LLPS-Pat-4559	Pan troglodytes	54.17	1e-80	250
LLPS-Hos-4391	Homo sapiens	54.17	2e-80	249
LLPS-Nol-3370	Nomascus leucogenys	54.17	1e-80	250
LLPS-Php-2472	Physcomitrella patens	54.03	2e-83	257
LLPS-Gaga-1499	Gallus gallus	53.94	8e-81	250
LLPS-Ori-2268	Oryza indica	53.91	5e-86	264
LLPS-Pap-3166	Pan paniscus	53.75	9e-80	248
LLPS-Caf-4393	Canis familiaris	53.75	2e-80	249
LLPS-Leo-1469	Lepisosteus oculatus	53.66	1e-80	250
LLPS-Gaa-3428	Gasterosteus aculeatus	53.56	9e-79	245
LLPS-Anp-0165	Anas platyrhynchos	53.54	7e-71	224
LLPS-Sah-3779	Sarcophilus harrisii	53.53	1e-80	250
LLPS-Myl-4475	Myotis lucifugus	53.53	2e-78	244
LLPS-Urm-3732	Ursus maritimus	53.53	3e-80	249
LLPS-Cis-1921	Ciona savignyi	53.44	2e-84	260
LLPS-Lem-1146	Leptosphaeria maculans	53.36	8e-89	272
LLPS-Loa-2550	Loxodonta africana	53.31	2e-79	247
LLPS-Fia-0727	Ficedula albicollis	53.18	5e-71	224
LLPS-Tut-1974	Tursiops truncatus	53.11	2e-79	247
LLPS-Fec-3257	Felis catus	52.92	1e-78	245
LLPS-Aim-3481	Ailuropoda melanoleuca	52.87	1e-80	250
LLPS-Ova-3595	Ovis aries	52.5	2e-78	244
LLPS-Tar-0239	Takifugu rubripes	52.46	9e-82	253
LLPS-Asfu-0786	Aspergillus fumigatus	52.43	7e-82	253
LLPS-Tag-1558	Taeniopygia guttata	52.4	9e-82	253
LLPS-Sus-4652	Sus scrofa	52.28	1e-77	243
LLPS-Bot-2171	Bos taurus	52.28	3e-78	244
LLPS-Mod-0366	Monodelphis domestica	52.28	9e-80	248
LLPS-Osl-0614	Ostreococcus lucimarinus	52.05	2e-78	244
LLPS-Scm-1068	Scophthalmus maximus	51.84	3e-74	234
LLPS-Cae-0546	Caenorhabditis elegans	51.82	3e-73	231
LLPS-Meg-1448	Meleagris gallopavo	50.89	4e-66	213
LLPS-Mal-3908	Mandrillus leucophaeus	50.79	2e-80	250
LLPS-Cas-0723	Carlito syrichta	50.79	2e-80	250
LLPS-Tru-0138	Triticum urartu	50.72	1e-83	259
LLPS-Mua-0992	Musa acuminata	50.68	2e-41	146
LLPS-Anc-2624	Anolis carolinensis	50.62	2e-77	242
LLPS-Poa-2887	Pongo abelii	50.39	9e-80	248
LLPS-Drm-2311	Drosophila melanogaster	50.21	2e-77	242
LLPS-Ora-1651	Ornithorhynchus anatinus	49.79	1e-69	221
LLPS-Ere-0494	Erinaceus europaeus	49.21	2e-73	232
LLPS-Phn-0938	Phaeosphaeria nodorum	48.74	4e-26	107
LLPS-Cym-0317	Cyanidioschyzon merolae	48.13	2e-73	232
LLPS-Xim-2624	Xiphophorus maculatus	46.91	1e-70	227
LLPS-Cog-0919	Colletotrichum gloeosporioides	45.2	1e-62	203
LLPS-Vir-1480	Vigna radiata	41.72	3e-52	178

LLPS-Crn-1449CNH00170

Protein Sequence

Nucleotide Sequence

LLPS-Crn-1449
CNH00170